Engineering Strategies for Regenerative Medicine considers how engineering strategies can be applied to accelerate advances in regenerative medicine. The book provides relevant and up-to-date content on key topics, including the interdisciplinary integration of different aspects of stem cell biology and technology, diverse technologies, and their applications. By providing massive amounts of data on each individual, recent scientific advances are rapidly accelerating medicine. Cellular, molecular and genetic parameters from biological samples combined with clinical information can now provide valuable data to scientists, clinicians and ultimately patients, leading to the development of precision medicine.
Equally noteworthy are the contributions of stem cell biology, bioengineering and tissue engineering that unravel the mechanisms of disease, regeneration and development.
1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. Contributors - p. vii 6. Engineering strategies for regenerative medicine - p. ix 7. Chapter 1: Pluripotent stem cell biology and engineering - p. xii 8. Chapter 2: Process development and manufacturing approaches for mesenchymal stem cell therapies - p. 31 9. Chapter 3: Bioinspired materials and tissue engineering approaches applied to the regeneration of musculoskeletal tissues - p. 71 10. Chapter 4: Bioengineering strategies for gene delivery - p. 105 11. Chapter 5: Advanced microtechnologies for high-throughput screening - p. 148 12. Chapter 6: Inductive factors for generation of pluripotent stem cell-derived cardiomyocytes - p. 175 13. Chapter 7: Pluripotent cells for the assessment of chemically induced teratogenesis and developmental toxicology - p. 242 14. Chapter 8: Conclusions and closing remarks - p. 258 15. Index - p. 263
Engineering Strategies for Regenerative Medicine considers how engineering strategies can be applied to accelerate advances in regenerative medicine. The book provides relevant and up-to-date content on key topics, including the interdisciplinary integration of different aspects of stem cell biology and technology, diverse technologies, and their applications. By providing massive amounts of data on each individual, recent scientific advances are rapidly accelerating medicine. Cellular, molecular and genetic parameters from biological samples combined with clinical information can now provide valuable data to scientists, clinicians and ultimately patients, leading to the development of precision medicine.
Equally noteworthy are the contributions of stem cell biology, bioengineering and tissue engineering that unravel the mechanisms of disease, regeneration and development.
1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. Contributors - p. vii 6. Engineering strategies for regenerative medicine - p. ix 7. Chapter 1: Pluripotent stem cell biology and engineering - p. xii 8. Chapter 2: Process development and manufacturing approaches for mesenchymal stem cell therapies - p. 31 9. Chapter 3: Bioinspired materials and tissue engineering approaches applied to the regeneration of musculoskeletal tissues - p. 71 10. Chapter 4: Bioengineering strategies for gene delivery - p. 105 11. Chapter 5: Advanced microtechnologies for high-throughput screening - p. 148 12. Chapter 6: Inductive factors for generation of pluripotent stem cell-derived cardiomyocytes - p. 175 13. Chapter 7: Pluripotent cells for the assessment of chemically induced teratogenesis and developmental toxicology - p. 242 14. Chapter 8: Conclusions and closing remarks - p. 258 15. Index - p. 263