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Enzinger and Weiss's Soft Tissue Tumors

1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iv 5. Dedication - p. v 6. Preface - p. vii 7. Preface to the First Edition - p. viii 8. Image Collection - p. xi 9. Contributors - p. vi 10. 1 General Considerations - p. vi 11. 2 Clinical Evaluation and Treatment of Soft Tissue Tumors - p. 14 12. 3 Radiologic Evaluation of Soft Tissue Tumors - p. 31 13. 4 Molecular Genetic Pathology of Soft Tissue Tumors - p. 83 14. Organization of the Human Genome: Implications for Molecular Genetic Pathology - p. 83 15. Constitutional Mutations Predisposing to Soft Tissue Tumors - p. 85 16. Somatic Mutations in Soft Tissue Tumors: General Concepts - p. 87 17. Genetic Techniques - p. 93 18. Characteristic Genetic Changes in Soft Tissue Tumors - p. 99 19. Conclusion - p. 110 20. Acknowledgments - p. 110 21. 5 Approach to the Diagnosis of Soft Tissue Tumors - p. 120 22. 6 Immunohistochemistry for Analysis of Soft Tissue Tumors - p. 128 23. Intermediate Filaments - p. 128 24. Epithelial Membrane Antigen - p. 137 25. Markers of Muscle Differentiation - p. 138 26. Markers of Nerve Sheath Differentiation - p. 145 27. “Neuroectodermal” Markers - p. 149 28. Markers of Melanocytic Differentiation - p. 154 29. Markers of Endothelial Differentiation - p. 155 30. Markers of Gastrointestinal Stromal Tumors - p. 163 31. Immunohistochemistry as Surrogate for Tumor-Specific Molecular Alterations - p. 163 32. Other Markers - p. 174 33. Prognostic Markers - p. 182 34. Application of Immunohistochemistry to Sarcoma Diagnosis: Clinical Scenarios - p. 184 35. Conclusion - p. 186 36. 7 Benign Fibroblastic/Myofibroblastic Proliferations, Including Superficial Fibromatoses - p. 201 37. Classification of Benign Fibroblastic/Myofibroblastic Proliferations - p. 203 38. Nodular Fasciitis - p. 203 39. Proliferative Fasciitis - p. 214 40. Proliferative Myositis - p. 218 41. Organ-Associated Pseudosarcomatous Myofibroblastic Proliferations - p. 219 42. Ischemic Fasciitis (Atypical Decubital Fibroplasia) - p. 225 43. Fibroma of Tendon Sheath - p. 227 44. Pleomorphic Fibroma of The Skin - p. 231 45. Nuchal-Type Fibroma - p. 232 46. Gardner-Associated Fibroma - p. 234 47. Elastofibroma - p. 235 48. Nasopharyngeal Angiofibroma - p. 237 49. Keloid - p. 240 50. Desmoplastic Fibroblastoma (Collagenous Fibroma) - p. 244 51. Intranodal Palisaded Myofibroblastoma - p. 246 52. Mammary-Type Myofibroblastoma - p. 248 53. Superficial Acral Fibromyxoma (Digital Fibromyxoma) - p. 253 54. Soft Tissue Angiofibroma - p. 254 55. Superficial Fibromatoses - p. 256 56. Palmar Fibromatosis (Dupuytren Disease) - p. 257 57. Plantar Fibromatosis (Ledderhose Disease) - p. 260 58. Penile Fibromatosis (Peyronie Disease) - p. 263 59. Knuckle Pads - p. 265 60. 8 Fibrous Tumors of Infancy and Childhood - p. 274 61. 9 Borderline and Malignant Fibroblastic/Myofibroblastic Tumors - p. 305 62. Deep (Desmoid-Type) Fibromatoses - p. 305 63. Congenital/Infantile Fibrosarcoma - p. 318 64. Inflammatory Myofibroblastic Tumor - p. 322 65. Adult-Type Fibrosarcoma - p. 330 66. Fibrosarcoma Variants - p. 336 67. 10 Benign Fibrohistiocytic Tumors - p. 374 68. 11 Fibrohistiocytic Tumors of Intermediate Malignancy - p. 423 69. 12 Undifferentiated Pleomorphic Sarcoma - p. 451 70. 13 Benign Lipomatous Tumors - p. 475 71. 14 Liposarcoma - p. 519 72. 15 Benign Tumors of Smooth Muscle - p. 563 73. 16 Leiomyosarcoma - p. 590 74. 17 Gastrointestinal Stromal Tumor (GIST) and Extragastrointestinal GIST - p. 613 75. 18 Rhabdomyoma - p. 638 76. 19 Rhabdomyosarcoma - p. 651 77. 20 Benign Vascular Tumors and Malformations - p. 696 78. 21 Hemangioendothelioma - p. 756 79. 22 Malignant Vascular Tumors - p. 784 80. 23 Tumors and Malformations of Lymphatic Vessels - p. 816 81. 24 Perivascular Tumors - p. 836 82. 25 Benign Tumors and Tumorlike Lesions of Synovial Tissue - p. 862 83. 26 Benign Tumors of Peripheral Nerves - p. 884 84. 27 Malignant Peripheral Nerve Sheath Tumors - p. 958 85. 28 Peripheral Neuroblastic Tumors - p. 990 86. 29 Soft Tissue Tumors Showing Melanocytic Differentiation - p. 1008 87. 30 Cartilaginous and Osseous Soft Tissue Tumors - p. 1051 88. 31 Miscellaneous Benign Soft Tissue Tumors and Pseudotumors - p. 1084 89. 32 Soft Tissue Tumors of Intermediate Malignancy of Uncertain Type - p. 1106 90. 33 Other Malignant Soft Tissue Tumors, Including Those of Uncertain Type - p. 1174 91. Ewing Sarcoma - p. 1174 92. CIC-Rearranged Sarcoma - p. 1186 93. BCOR-Rearranged Sarcoma - p. 1191 94. Extraskeletal Myxoid Chondrosarcoma - p. 1194 95. Synovial Sarcoma - p. 1200 96. Alveolar Soft Part Sarcoma - p. 1218 97. Desmoplastic Small Round Cell Tumor - p. 1227 98. Epithelioid Sarcoma - p. 1231 99. Malignant Extrarenal Rhabdoid Tumor - p. 1242 100. Follicular Dendritic Cell Sarcoma - p. 1247 101. GLI1-Rearranged Malignant Epithelioid Neoplasm - p. 1249 102. Index - p. 1270

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Enzinger and Weiss's Soft Tissue Tumors

1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iv 5. Dedication - p. v 6. Preface - p. vii 7. Preface to the First Edition - p. viii 8. Image Collection - p. xi 9. Contributors - p. vi 10. 1 General Considerations - p. vi 11. 2 Clinical Evaluation and Treatment of Soft Tissue Tumors - p. 14 12. 3 Radiologic Evaluation of Soft Tissue Tumors - p. 31 13. 4 Molecular Genetic Pathology of Soft Tissue Tumors - p. 83 14. Organization of the Human Genome: Implications for Molecular Genetic Pathology - p. 83 15. Constitutional Mutations Predisposing to Soft Tissue Tumors - p. 85 16. Somatic Mutations in Soft Tissue Tumors: General Concepts - p. 87 17. Genetic Techniques - p. 93 18. Characteristic Genetic Changes in Soft Tissue Tumors - p. 99 19. Conclusion - p. 110 20. Acknowledgments - p. 110 21. 5 Approach to the Diagnosis of Soft Tissue Tumors - p. 120 22. 6 Immunohistochemistry for Analysis of Soft Tissue Tumors - p. 128 23. Intermediate Filaments - p. 128 24. Epithelial Membrane Antigen - p. 137 25. Markers of Muscle Differentiation - p. 138 26. Markers of Nerve Sheath Differentiation - p. 145 27. “Neuroectodermal” Markers - p. 149 28. Markers of Melanocytic Differentiation - p. 154 29. Markers of Endothelial Differentiation - p. 155 30. Markers of Gastrointestinal Stromal Tumors - p. 163 31. Immunohistochemistry as Surrogate for Tumor-Specific Molecular Alterations - p. 163 32. Other Markers - p. 174 33. Prognostic Markers - p. 182 34. Application of Immunohistochemistry to Sarcoma Diagnosis: Clinical Scenarios - p. 184 35. Conclusion - p. 186 36. 7 Benign Fibroblastic/Myofibroblastic Proliferations, Including Superficial Fibromatoses - p. 201 37. Classification of Benign Fibroblastic/Myofibroblastic Proliferations - p. 203 38. Nodular Fasciitis - p. 203 39. Proliferative Fasciitis - p. 214 40. Proliferative Myositis - p. 218 41. Organ-Associated Pseudosarcomatous Myofibroblastic Proliferations - p. 219 42. Ischemic Fasciitis (Atypical Decubital Fibroplasia) - p. 225 43. Fibroma of Tendon Sheath - p. 227 44. Pleomorphic Fibroma of The Skin - p. 231 45. Nuchal-Type Fibroma - p. 232 46. Gardner-Associated Fibroma - p. 234 47. Elastofibroma - p. 235 48. Nasopharyngeal Angiofibroma - p. 237 49. Keloid - p. 240 50. Desmoplastic Fibroblastoma (Collagenous Fibroma) - p. 244 51. Intranodal Palisaded Myofibroblastoma - p. 246 52. Mammary-Type Myofibroblastoma - p. 248 53. Superficial Acral Fibromyxoma (Digital Fibromyxoma) - p. 253 54. Soft Tissue Angiofibroma - p. 254 55. Superficial Fibromatoses - p. 256 56. Palmar Fibromatosis (Dupuytren Disease) - p. 257 57. Plantar Fibromatosis (Ledderhose Disease) - p. 260 58. Penile Fibromatosis (Peyronie Disease) - p. 263 59. Knuckle Pads - p. 265 60. 8 Fibrous Tumors of Infancy and Childhood - p. 274 61. 9 Borderline and Malignant Fibroblastic/Myofibroblastic Tumors - p. 305 62. Deep (Desmoid-Type) Fibromatoses - p. 305 63. Congenital/Infantile Fibrosarcoma - p. 318 64. Inflammatory Myofibroblastic Tumor - p. 322 65. Adult-Type Fibrosarcoma - p. 330 66. Fibrosarcoma Variants - p. 336 67. 10 Benign Fibrohistiocytic Tumors - p. 374 68. 11 Fibrohistiocytic Tumors of Intermediate Malignancy - p. 423 69. 12 Undifferentiated Pleomorphic Sarcoma - p. 451 70. 13 Benign Lipomatous Tumors - p. 475 71. 14 Liposarcoma - p. 519 72. 15 Benign Tumors of Smooth Muscle - p. 563 73. 16 Leiomyosarcoma - p. 590 74. 17 Gastrointestinal Stromal Tumor (GIST) and Extragastrointestinal GIST - p. 613 75. 18 Rhabdomyoma - p. 638 76. 19 Rhabdomyosarcoma - p. 651 77. 20 Benign Vascular Tumors and Malformations - p. 696 78. 21 Hemangioendothelioma - p. 756 79. 22 Malignant Vascular Tumors - p. 784 80. 23 Tumors and Malformations of Lymphatic Vessels - p. 816 81. 24 Perivascular Tumors - p. 836 82. 25 Benign Tumors and Tumorlike Lesions of Synovial Tissue - p. 862 83. 26 Benign Tumors of Peripheral Nerves - p. 884 84. 27 Malignant Peripheral Nerve Sheath Tumors - p. 958 85. 28 Peripheral Neuroblastic Tumors - p. 990 86. 29 Soft Tissue Tumors Showing Melanocytic Differentiation - p. 1008 87. 30 Cartilaginous and Osseous Soft Tissue Tumors - p. 1051 88. 31 Miscellaneous Benign Soft Tissue Tumors and Pseudotumors - p. 1084 89. 32 Soft Tissue Tumors of Intermediate Malignancy of Uncertain Type - p. 1106 90. 33 Other Malignant Soft Tissue Tumors, Including Those of Uncertain Type - p. 1174 91. Ewing Sarcoma - p. 1174 92. CIC-Rearranged Sarcoma - p. 1186 93. BCOR-Rearranged Sarcoma - p. 1191 94. Extraskeletal Myxoid Chondrosarcoma - p. 1194 95. Synovial Sarcoma - p. 1200 96. Alveolar Soft Part Sarcoma - p. 1218 97. Desmoplastic Small Round Cell Tumor - p. 1227 98. Epithelioid Sarcoma - p. 1231 99. Malignant Extrarenal Rhabdoid Tumor - p. 1242 100. Follicular Dendritic Cell Sarcoma - p. 1247 101. GLI1-Rearranged Malignant Epithelioid Neoplasm - p. 1249 102. Index - p. 1270

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