Epigenetic Regulation of Cancer in Response to Chemotherapy, Volume 158 of the Advances in Cancer Research series, highlights new advances in the field, with this new volume presenting chapters on timely topics, including Epigenetically Programmed Resistance to Chemotherapy and Promotion of Immune Evasion in Cancer, A Role for the Epigenome in Cancer Cell Drug Tolerance, Histone Methylation and X Chromosomal Genes in Metastasis of Breast Cancer, Targeting Epigenetic Regulation Using Small Molecule Inhibitors, Histone Deacetylase Inhibitors as Sanguine Epigenetic Therapeutics against Pugnacious Lung Cancer, From ecology to oncology: To understand cancer stem cell dormancy, ask a Brine shrimp (Artemia), and more.
Additional chapters cover Predictive Models of Chemoresistance Generated by Crunching the Public Drug Screen, Epigenomic and Genomic Profiling Datasets via Regression-, Machine Learning, and Knowledge-Based Methods, Probing on the Mechanisms of lncRNAs on Cancer Drug Resistance, Drug Tolerant Persister Cells in Cancer: Current Knowledge and Therapeutic Perspectives, and much more.
1. 1 Introduction - p. 76 2. 2 DNA methylation - p. 78 3. 3 Histone modifications - p. 87 4. 4 Combination epigenetic therapy - p. 125 5. 5 Conclusions - p. 130 6. References - p. 132 7. Further reading - p. 161 8. Chapter Four: Histone deacetylase inhibitors as sanguine epitherapeutics against the deadliest lung cancer - p. 186 9. Chapter Five: From ecology to oncology: To understand cancer stem cell dormancy, ask a Brine shrimp (Artemia) - p. 206 10. Chapter Six: Multi-CpG linear regression models to accurately predict paclitaxel and docetaxel activity in cancer cell lines - p. 244 11. Chapter Seven: Epigenetic adaptations in drug-tolerant tumor cells - p. 293 12. Chapter Eight: The epigenetic regulation of cancer cell recovery from therapy exposure and its implications as a novel therapeutic strategy for preventing disease recurrence - p. 337 13. Chapter Nine: Targeting the super elongation complex for oncogenic transcription driven tumor malignancies: Progress in structure, mechanisms and small molecular inhibitor discovery - p. 387
Epigenetic Regulation of Cancer in Response to Chemotherapy, Volume 158 of the Advances in Cancer Research series, highlights new advances in the field, with this new volume presenting chapters on timely topics, including Epigenetically Programmed Resistance to Chemotherapy and Promotion of Immune Evasion in Cancer, A Role for the Epigenome in Cancer Cell Drug Tolerance, Histone Methylation and X Chromosomal Genes in Metastasis of Breast Cancer, Targeting Epigenetic Regulation Using Small Molecule Inhibitors, Histone Deacetylase Inhibitors as Sanguine Epigenetic Therapeutics against Pugnacious Lung Cancer, From ecology to oncology: To understand cancer stem cell dormancy, ask a Brine shrimp (Artemia), and more.
Additional chapters cover Predictive Models of Chemoresistance Generated by Crunching the Public Drug Screen, Epigenomic and Genomic Profiling Datasets via Regression-, Machine Learning, and Knowledge-Based Methods, Probing on the Mechanisms of lncRNAs on Cancer Drug Resistance, Drug Tolerant Persister Cells in Cancer: Current Knowledge and Therapeutic Perspectives, and much more.
1. 1 Introduction - p. 76 2. 2 DNA methylation - p. 78 3. 3 Histone modifications - p. 87 4. 4 Combination epigenetic therapy - p. 125 5. 5 Conclusions - p. 130 6. References - p. 132 7. Further reading - p. 161 8. Chapter Four: Histone deacetylase inhibitors as sanguine epitherapeutics against the deadliest lung cancer - p. 186 9. Chapter Five: From ecology to oncology: To understand cancer stem cell dormancy, ask a Brine shrimp (Artemia) - p. 206 10. Chapter Six: Multi-CpG linear regression models to accurately predict paclitaxel and docetaxel activity in cancer cell lines - p. 244 11. Chapter Seven: Epigenetic adaptations in drug-tolerant tumor cells - p. 293 12. Chapter Eight: The epigenetic regulation of cancer cell recovery from therapy exposure and its implications as a novel therapeutic strategy for preventing disease recurrence - p. 337 13. Chapter Nine: Targeting the super elongation complex for oncogenic transcription driven tumor malignancies: Progress in structure, mechanisms and small molecular inhibitor discovery - p. 387