Extracellular Vesicle-Based Biovectors for Diagnostic and Biomedical Applications provides comprehensive coverage on not only the biosynthesis, isolation, purification, and functionalization of extracellular vesicles for therapeutic and diagnostic applications, but also current trends in functionalized extracellular vesicles for biomedical research and commercial-scale opportunities. Sections focus on the fundamental aspects of extracellular vesicles, covering their origin, classification, biosynthesis, isolation techniques, purification challenges, and functionalization for biomedical applications, while also delving into the therapeutic applications of extracellular vesicles and their role in treating diseases.
Content also address biocompatibility, safety, translation challenges, biocompatibility, and translation challenges. Final sections explore the diagnostic potential of extracellular vesicles in biomedical research, highlighting their role as diagnostic biomarkers in various diseases. Emerging technologies and future directions in extracellular vesicle research round out the content, making it a valuable reference for researchers and clinicians seeking an in-depth understanding of extracellular vesicles and their potential biomedical applications.
1. Introduction - p. xv 2. Part I: Introduction: Extracellular vesicles origin, classifications and biosynthesis, isolation approaches, purification, and functionalization of extracellular vesicles for biomedical applications and new perspectives - p. P1 3. Chapter 1 Introduction to extracellular vesicles: Origin, classification, and biosynthesis - p. 3 4. Chapter 2 Isolation, purification, and challenges in extracellular vesicles - p. 25 5. Chapter 3 Characterization of extracellular vesicles: Techniques and technologies - p. 55 6. Chapter 4 Drug loading techniques for extracellular vesicles for biomedical applications - p. 85 7. Chapter 5 Functionalization of extracellular vesicles for biomedical applications - p. 119 8. Part II: Therapeutic applications of extracellular vesicles - p. P2 9. Chapter 6 Extracellular vesicles in musculoskeletal and cardiovascular applications - p. 143 10. Chapter 7 Extracellular vesicles in neurodegenerative diseases - p. 173 11. Chapter 8 Extracellular vesicles in autoimmune diseases and immunotherapy - p. 219 12. Chapter 9 Extracellular vesicles in the diagnosis of diabetes mellitus and associated complications - p. 241 13. Chapter 10 Extracellular vesicles in cancer therapy - p. 261 14. Chapter 11 Emerging applications of extracellular vesicles in regenerative medicine and tissue engineering - p. 289 15. Chapter 12 Biocompatibility, safety, and challenges in commercial, regulatory, and clinical translation - p. 313 16. Part III: Diagnostic applications of extracellular vesicles in biomedical research - p. P3 17. Chapter 13 Extracellular vesicles as diagnostic biomarkers in cancer research - p. 339 18. Chapter 14 Extracellular vesicles in the diagnosis of diabetes mellitus and associated complications - p. 363 19. Chapter 15 Diagnostic application of extracellular vesicles as biomarkers in neurological disorders - p. 389 20. Chapter 16 Prognostic and diagnostic applications of extracellular vesicles in cardiovascular diseases - p. 411 21. Chapter 17 Extracellular vesicles in the diagnosis of autoimmune diseases - p. 429 22. Chapter 18 Emerging technologies and future directions in extracellular vesicle research - p. 457 23. Index - p. 495
Extracellular Vesicle-Based Biovectors for Diagnostic and Biomedical Applications provides comprehensive coverage on not only the biosynthesis, isolation, purification, and functionalization of extracellular vesicles for therapeutic and diagnostic applications, but also current trends in functionalized extracellular vesicles for biomedical research and commercial-scale opportunities. Sections focus on the fundamental aspects of extracellular vesicles, covering their origin, classification, biosynthesis, isolation techniques, purification challenges, and functionalization for biomedical applications, while also delving into the therapeutic applications of extracellular vesicles and their role in treating diseases.
Content also address biocompatibility, safety, translation challenges, biocompatibility, and translation challenges. Final sections explore the diagnostic potential of extracellular vesicles in biomedical research, highlighting their role as diagnostic biomarkers in various diseases. Emerging technologies and future directions in extracellular vesicle research round out the content, making it a valuable reference for researchers and clinicians seeking an in-depth understanding of extracellular vesicles and their potential biomedical applications.
1. Introduction - p. xv 2. Part I: Introduction: Extracellular vesicles origin, classifications and biosynthesis, isolation approaches, purification, and functionalization of extracellular vesicles for biomedical applications and new perspectives - p. P1 3. Chapter 1 Introduction to extracellular vesicles: Origin, classification, and biosynthesis - p. 3 4. Chapter 2 Isolation, purification, and challenges in extracellular vesicles - p. 25 5. Chapter 3 Characterization of extracellular vesicles: Techniques and technologies - p. 55 6. Chapter 4 Drug loading techniques for extracellular vesicles for biomedical applications - p. 85 7. Chapter 5 Functionalization of extracellular vesicles for biomedical applications - p. 119 8. Part II: Therapeutic applications of extracellular vesicles - p. P2 9. Chapter 6 Extracellular vesicles in musculoskeletal and cardiovascular applications - p. 143 10. Chapter 7 Extracellular vesicles in neurodegenerative diseases - p. 173 11. Chapter 8 Extracellular vesicles in autoimmune diseases and immunotherapy - p. 219 12. Chapter 9 Extracellular vesicles in the diagnosis of diabetes mellitus and associated complications - p. 241 13. Chapter 10 Extracellular vesicles in cancer therapy - p. 261 14. Chapter 11 Emerging applications of extracellular vesicles in regenerative medicine and tissue engineering - p. 289 15. Chapter 12 Biocompatibility, safety, and challenges in commercial, regulatory, and clinical translation - p. 313 16. Part III: Diagnostic applications of extracellular vesicles in biomedical research - p. P3 17. Chapter 13 Extracellular vesicles as diagnostic biomarkers in cancer research - p. 339 18. Chapter 14 Extracellular vesicles in the diagnosis of diabetes mellitus and associated complications - p. 363 19. Chapter 15 Diagnostic application of extracellular vesicles as biomarkers in neurological disorders - p. 389 20. Chapter 16 Prognostic and diagnostic applications of extracellular vesicles in cardiovascular diseases - p. 411 21. Chapter 17 Extracellular vesicles in the diagnosis of autoimmune diseases - p. 429 22. Chapter 18 Emerging technologies and future directions in extracellular vesicle research - p. 457 23. Index - p. 495
