Forkhead FOXO Transcription Factors in Development and Disease, Volume 127, the latest release in the Current Topics in Developmental Biology series, provides a comprehensive set of reviews on transcription factors FOXO and their various functions in health and disease. Each chapter is contributed by a leading expert in the field, with specific sections covering Exceptional Longevity: Insights from Hydra to Humans, FOXO in neural cells and diseases of the nervous system, maintaining the equilibrium for better or for worse, and The Role of FoxOs in Bone Health and Disease, amongst other topics.
This compilation provides a unique, up-to-date view of this enigmatic, highly evolutionary conserved family of transcription factors with a diverse array of functions in aging and longevity, cancer, and metabolism.
1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. Contributors - p. ix 6. Preface - p. xi 7. Chapter One: DAF-16: FOXO in the Context of C. elegans - p. xii 8. Chapter Two: Stem Cells Seen Through the FOXO Lens: An Evolving Paradigm - p. 21 9. Chapter Three: FOXOs Maintaining the Equilibrium for Better or for Worse - p. 47 10. Chapter Four: FOXO in Neural Cells and Diseases of the Nervous System - p. 103 11. Chapter Five: Regulation of Hepatic Glucose Metabolism by FoxO Proteins, an Integrated Approach - p. 118 12. Chapter Six: The Role of FoxOs in Bone Health and Disease - p. 147 13. Chapter Seven: Regulation of FOXO Factors in Mammalian Cells - p. 163 14. Chapter Eight: FOXO3 and Exceptional Longevity: Insights From Hydra to Humans - p. 192
Forkhead FOXO Transcription Factors in Development and Disease, Volume 127, the latest release in the Current Topics in Developmental Biology series, provides a comprehensive set of reviews on transcription factors FOXO and their various functions in health and disease. Each chapter is contributed by a leading expert in the field, with specific sections covering Exceptional Longevity: Insights from Hydra to Humans, FOXO in neural cells and diseases of the nervous system, maintaining the equilibrium for better or for worse, and The Role of FoxOs in Bone Health and Disease, amongst other topics.
This compilation provides a unique, up-to-date view of this enigmatic, highly evolutionary conserved family of transcription factors with a diverse array of functions in aging and longevity, cancer, and metabolism.
1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. Contributors - p. ix 6. Preface - p. xi 7. Chapter One: DAF-16: FOXO in the Context of C. elegans - p. xii 8. Chapter Two: Stem Cells Seen Through the FOXO Lens: An Evolving Paradigm - p. 21 9. Chapter Three: FOXOs Maintaining the Equilibrium for Better or for Worse - p. 47 10. Chapter Four: FOXO in Neural Cells and Diseases of the Nervous System - p. 103 11. Chapter Five: Regulation of Hepatic Glucose Metabolism by FoxO Proteins, an Integrated Approach - p. 118 12. Chapter Six: The Role of FoxOs in Bone Health and Disease - p. 147 13. Chapter Seven: Regulation of FOXO Factors in Mammalian Cells - p. 163 14. Chapter Eight: FOXO3 and Exceptional Longevity: Insights From Hydra to Humans - p. 192
