This issue of Progress in Brain Research is split over 2 volumes, bringing together cutting-edge research on functional neural transplantation. The 2 volumes review current knowledge and understanding, provide a starting point for researchers and practitioners entering the field, and build a platform for further research and discovery.
Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future research
Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered
All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist
1. Chapter 1. Introduction (Part I) 2. Chapter 2. Transplantation in the future 3. Chapter 3. Ethical challenges for using human cells in clinical cell therapy 4. Chapter 4. Banking stem cells for research and clinical applications 5. Chapter 5. Survival, differentiation, and connectivity of ventral mesencephalic dopamine neurons following transplantation 6. Chapter 6. Electrophysiological investigations of synaptic connectivity between host and graft neurons 7. Chapter 7. Nigral grafts in animal models of Parkinson’s disease. Is recovery beyond motor function possible? 8. Chapter 8. L-DOPA- and graft-induced dyskinesia following transplantation 9. Chapter 9. Current status of clinical trials of neural transplantation in Parkinson’s disease 10. Chapter 10. In vivo imaging of the integration and function of nigral grafts in clinical trials 11. Chapter 11. Neuropathology in transplants in Parkinson’s disease 12. Chapter 12. Derivation of dopaminergic neurons from pluripotent stem cells 13. Chapter 13. Characterization and criteria of embryonic stem and induced pluripotent stem cells for a dopamine replacement therapy 14. Chapter 14. Skilled motor control for the preclinical assessment of functional deficits and recovery following nigral and striatal cell transplantation 15. Chapter 15. Role of experience, training, and plasticity in the functional efficacy of striatal transplants 16. Chapter 16. In vivo imaging of integration and function of striatal grafts in rodent and nonhuman primate animal models 17. Chapter 17. Clinical trials of neural transplantation in Huntington’s disease 18. Chapter 18. Derivation of striatal neurons from human stem cells 19. Combined Index 20. Other volumes in PROGRESS IN BRAIN RESEARCH
This issue of Progress in Brain Research is split over 2 volumes, bringing together cutting-edge research on functional neural transplantation. The 2 volumes review current knowledge and understanding, provide a starting point for researchers and practitioners entering the field, and build a platform for further research and discovery.
Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future research
Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered
All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist
1. Chapter 1. Introduction (Part I) 2. Chapter 2. Transplantation in the future 3. Chapter 3. Ethical challenges for using human cells in clinical cell therapy 4. Chapter 4. Banking stem cells for research and clinical applications 5. Chapter 5. Survival, differentiation, and connectivity of ventral mesencephalic dopamine neurons following transplantation 6. Chapter 6. Electrophysiological investigations of synaptic connectivity between host and graft neurons 7. Chapter 7. Nigral grafts in animal models of Parkinson’s disease. Is recovery beyond motor function possible? 8. Chapter 8. L-DOPA- and graft-induced dyskinesia following transplantation 9. Chapter 9. Current status of clinical trials of neural transplantation in Parkinson’s disease 10. Chapter 10. In vivo imaging of the integration and function of nigral grafts in clinical trials 11. Chapter 11. Neuropathology in transplants in Parkinson’s disease 12. Chapter 12. Derivation of dopaminergic neurons from pluripotent stem cells 13. Chapter 13. Characterization and criteria of embryonic stem and induced pluripotent stem cells for a dopamine replacement therapy 14. Chapter 14. Skilled motor control for the preclinical assessment of functional deficits and recovery following nigral and striatal cell transplantation 15. Chapter 15. Role of experience, training, and plasticity in the functional efficacy of striatal transplants 16. Chapter 16. In vivo imaging of integration and function of striatal grafts in rodent and nonhuman primate animal models 17. Chapter 17. Clinical trials of neural transplantation in Huntington’s disease 18. Chapter 18. Derivation of striatal neurons from human stem cells 19. Combined Index 20. Other volumes in PROGRESS IN BRAIN RESEARCH
