Fundamentals and Applications of Fourier Transform Mass Spectrometry is the first book to delve into the underlying principles on the topic and their linkage to industrial applications. Drs. Schmitt-Kopplin and Kanawati have brought together a team of leading experts in their respective fields to present this technique from many different perspectives, describing, at length, the pros and cons of FT-ICR and Orbitrap. Numerous examples help researchers decide which instruments to use for their particular scientific problem and which data analysis methods should be applied to get the most out of their data.
1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. Contributors - p. xiii 6. Foreword - p. xvii 7. Preface - p. xix 8. Acknowledgments - p. xxiii 9. Section A: Historical chapters - p. xxiii 10. Chapter 1: Historical developments in Fourier transform ion cyclotron resonance mass spectrometry - p. xxiii 11. Section B: Fundamental/technology chapters - p. 33 12. Chapter 2: Fundamentals of Orbitrap analyzer - p. 33 13. Chapter 3: Fundamentals, strengths, and future directions for Fourier transform ion cyclotron resonance mass spectrometry - p. 61 14. Chapter 4: Fundamentals and simulations in FT-ICR-MS - p. 88 15. Chapter 5: Advanced fundamentals in Fourier transform mass spectrometry - p. 111 16. Chapter 6: Data processing and automation in Fourier transform mass spectrometry - p. 132 17. Chapter 7: Fundamentals of two dimensional Fourier transform mass spectrometry - p. 185 18. Chapter 8: Trapped ion mobility spectrometry coupled to FT-ICR MS: Fundamentals and applications - p. 232 19. Chapter 9: In situ metabolomics in cancer tissue by high-resolution mass spectrometry imaging - p. 251 20. Chapter 10: Fourier transform ion cyclotron resonance mass spectrometry and laser: A versatile tool - p. 279 21. Section C: Applications chapters - p. 322 22. Chapter 11: Metabolomics using Fourier transform mass spectrometry - p. 322 23. Chapter 12: Mass differences in metabolome analyses of untargeted direct infusion ultra-high resolution MS data - p. 356 24. Chapter 13: FT-ICR MS and Orbitrap mass spectrometry approaches in environmental chemistry - p. 405 25. Chapter 14: Identification of biologically active peptides by means of Fourier transform mass spectrometry - p. 423 26. Chapter 15: Fourier transform mass spectrometry applied to Forensic Chemistry - p. 468 27. Chapter 16: Fourier transform mass spectrometry applied to petroleomics - p. 508 28. Chapter 17: Proteomics and proteoforms: Bottom-up or top-down, how to use high-resolution mass spectrometry to reach the Grail - p. 528 29. Chapter 18: Gas phase ion-molecule reactions of inorganic compounds in FT-ICR-MS - p. 567 30. Chapter 19: Cryo trapping by FT-MS for kinetics and spectroscopy - p. 591 31. Chapter 20: Application of FTMS to the analysis of glycosaminoglycans - p. 621 32. Chapter 21: Foodomics assessed by Fourier transform mass spectrometry - p. 649 33. Chapter 22: Contribution of Fourier transform mass spectrometry to bio-oil study - p. 677 34. Index - p. 735
Fundamentals and Applications of Fourier Transform Mass Spectrometry is the first book to delve into the underlying principles on the topic and their linkage to industrial applications. Drs. Schmitt-Kopplin and Kanawati have brought together a team of leading experts in their respective fields to present this technique from many different perspectives, describing, at length, the pros and cons of FT-ICR and Orbitrap. Numerous examples help researchers decide which instruments to use for their particular scientific problem and which data analysis methods should be applied to get the most out of their data.
1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. Contributors - p. xiii 6. Foreword - p. xvii 7. Preface - p. xix 8. Acknowledgments - p. xxiii 9. Section A: Historical chapters - p. xxiii 10. Chapter 1: Historical developments in Fourier transform ion cyclotron resonance mass spectrometry - p. xxiii 11. Section B: Fundamental/technology chapters - p. 33 12. Chapter 2: Fundamentals of Orbitrap analyzer - p. 33 13. Chapter 3: Fundamentals, strengths, and future directions for Fourier transform ion cyclotron resonance mass spectrometry - p. 61 14. Chapter 4: Fundamentals and simulations in FT-ICR-MS - p. 88 15. Chapter 5: Advanced fundamentals in Fourier transform mass spectrometry - p. 111 16. Chapter 6: Data processing and automation in Fourier transform mass spectrometry - p. 132 17. Chapter 7: Fundamentals of two dimensional Fourier transform mass spectrometry - p. 185 18. Chapter 8: Trapped ion mobility spectrometry coupled to FT-ICR MS: Fundamentals and applications - p. 232 19. Chapter 9: In situ metabolomics in cancer tissue by high-resolution mass spectrometry imaging - p. 251 20. Chapter 10: Fourier transform ion cyclotron resonance mass spectrometry and laser: A versatile tool - p. 279 21. Section C: Applications chapters - p. 322 22. Chapter 11: Metabolomics using Fourier transform mass spectrometry - p. 322 23. Chapter 12: Mass differences in metabolome analyses of untargeted direct infusion ultra-high resolution MS data - p. 356 24. Chapter 13: FT-ICR MS and Orbitrap mass spectrometry approaches in environmental chemistry - p. 405 25. Chapter 14: Identification of biologically active peptides by means of Fourier transform mass spectrometry - p. 423 26. Chapter 15: Fourier transform mass spectrometry applied to Forensic Chemistry - p. 468 27. Chapter 16: Fourier transform mass spectrometry applied to petroleomics - p. 508 28. Chapter 17: Proteomics and proteoforms: Bottom-up or top-down, how to use high-resolution mass spectrometry to reach the Grail - p. 528 29. Chapter 18: Gas phase ion-molecule reactions of inorganic compounds in FT-ICR-MS - p. 567 30. Chapter 19: Cryo trapping by FT-MS for kinetics and spectroscopy - p. 591 31. Chapter 20: Application of FTMS to the analysis of glycosaminoglycans - p. 621 32. Chapter 21: Foodomics assessed by Fourier transform mass spectrometry - p. 649 33. Chapter 22: Contribution of Fourier transform mass spectrometry to bio-oil study - p. 677 34. Index - p. 735
