Fundamentals of Molecular Structural Biology reviews the mathematical and physical foundations of molecular structural biology. Based on these fundamental concepts, it then describes molecular structure and explains basic genetic mechanisms. Given the increasingly interdisciplinary nature of research, early career researchers and those shifting into an adjacent field often require a "fundamentals" book to get them up-to-speed on the foundations of a particular field. This book fills that niche.
1. Chapter 1: Introduction—A historical perspective - p. xxi 2. Chapter 2: Mathematical tools - p. 10 3. Chapter 3: Physical basis of chemistry - p. 32 4. Chapter 4: Chemical basis of biology - p. 57 5. Chapter 5: Biomacromolecules - p. 82 6. Chapter 6: Structure analysis and visualization - p. 117 7. Chapter 7: Protein folding - p. 146 8. Chapter 8: DNA synthesis: Replication - p. 169 9. Chapter 9: Transcription - p. 216 10. Chapter 10: RNA processing - p. 276 11. Chapter 11: Translation - p. 309 12. Chapter 12: DNA damage and repair - p. 346 13. Chapter 13: Recombination - p. 376 14. Chapter 14: Membrane structure and function - p. 404 15. Chapter 15: Fundamentals of structural genomics - p. 420 16. Chapter 16: Cell signaling and systems biology - p. 431 17. Chapter 17: Macromolecular assemblies - p. 448 18. Chapter 18: Computational molecular biology - p. 463 19. Index - p. 481
Fundamentals of Molecular Structural Biology reviews the mathematical and physical foundations of molecular structural biology. Based on these fundamental concepts, it then describes molecular structure and explains basic genetic mechanisms. Given the increasingly interdisciplinary nature of research, early career researchers and those shifting into an adjacent field often require a "fundamentals" book to get them up-to-speed on the foundations of a particular field. This book fills that niche.
1. Chapter 1: Introduction—A historical perspective - p. xxi 2. Chapter 2: Mathematical tools - p. 10 3. Chapter 3: Physical basis of chemistry - p. 32 4. Chapter 4: Chemical basis of biology - p. 57 5. Chapter 5: Biomacromolecules - p. 82 6. Chapter 6: Structure analysis and visualization - p. 117 7. Chapter 7: Protein folding - p. 146 8. Chapter 8: DNA synthesis: Replication - p. 169 9. Chapter 9: Transcription - p. 216 10. Chapter 10: RNA processing - p. 276 11. Chapter 11: Translation - p. 309 12. Chapter 12: DNA damage and repair - p. 346 13. Chapter 13: Recombination - p. 376 14. Chapter 14: Membrane structure and function - p. 404 15. Chapter 15: Fundamentals of structural genomics - p. 420 16. Chapter 16: Cell signaling and systems biology - p. 431 17. Chapter 17: Macromolecular assemblies - p. 448 18. Chapter 18: Computational molecular biology - p. 463 19. Index - p. 481
