Fungal and Protozoan Carbonic Anhydrases, Volume 57 in The Enzymes series, explores recent advancements in the study of fungal and protozoan carbonic anhydrases (CAs). This volume presents a comprehensive collection of chapters covering various aspects of these enzymes, including an overview of fungal and protozoan CAs (genetics, molecular biology, and phylogenetics), the structure and function of fungal α-carbonic anhydrases, and an in-depth look at β-carbonic anhydrases in Saccharomyces cerevisiae, Candida spp., and Cryptococcus neoformans.
Additional chapters delve into the Malassezia spp. and Sordaria macrospora CAs, as well as protozoan CAs from Plasmodium falciparum, Trypanosoma cruzi, Leishmania spp., Toxoplasma gondii, and Entamoeba histolytica. The volume also addresses the challenges in developing selective fungal and protozoal CA inhibitors as anti-infective agents, providing insights into their potential biomedical applications.
1. Cover image - p. i 2. Fungal and Protozoan Carbonic Anhydrases - p. ii 3. Title page - p. iii 4. Copyright - p. iv 5. Table of Contents - p. v 6. Contributors - p. ix 7. Preface - p. xi 8. 1 Overview on fungal and protozoan carbonic anhydrases - p. 1 9. 2 Fungal α-carbonic anhydrases - p. 21 10. 3 Saccharomyces cerevesiae, Candida spp. and Cryptococcus neoformans β-CAs - p. 33 11. 4 Malassezia spp. carbonic anhydrases - p. 65 12. 5 Sordaria macrospora carbonic anhydrases - p. 91 13. 6 Plasmodium falciparum η-carbonic anhydrase - p. 113 14. 7 Trypanosoma cruzi and Leishmania spp. CAs - p. 129 15. 8 Toxoplasma gondii, babesia, and other protozoan carbonic anhydrases - p. 183 16. 9 Trichomonas vaginalis carbonic anhydrase - p. 207 17. 10 Entamoeba histolytica carbonic anhydrase - p. 219 18. 11 Challenges for developing selective fungal/protozoal carbonic anhydrase inhibitors as anti-infectives - p. 229
Fungal and Protozoan Carbonic Anhydrases, Volume 57 in The Enzymes series, explores recent advancements in the study of fungal and protozoan carbonic anhydrases (CAs). This volume presents a comprehensive collection of chapters covering various aspects of these enzymes, including an overview of fungal and protozoan CAs (genetics, molecular biology, and phylogenetics), the structure and function of fungal α-carbonic anhydrases, and an in-depth look at β-carbonic anhydrases in Saccharomyces cerevisiae, Candida spp., and Cryptococcus neoformans.
Additional chapters delve into the Malassezia spp. and Sordaria macrospora CAs, as well as protozoan CAs from Plasmodium falciparum, Trypanosoma cruzi, Leishmania spp., Toxoplasma gondii, and Entamoeba histolytica. The volume also addresses the challenges in developing selective fungal and protozoal CA inhibitors as anti-infective agents, providing insights into their potential biomedical applications.
1. Cover image - p. i 2. Fungal and Protozoan Carbonic Anhydrases - p. ii 3. Title page - p. iii 4. Copyright - p. iv 5. Table of Contents - p. v 6. Contributors - p. ix 7. Preface - p. xi 8. 1 Overview on fungal and protozoan carbonic anhydrases - p. 1 9. 2 Fungal α-carbonic anhydrases - p. 21 10. 3 Saccharomyces cerevesiae, Candida spp. and Cryptococcus neoformans β-CAs - p. 33 11. 4 Malassezia spp. carbonic anhydrases - p. 65 12. 5 Sordaria macrospora carbonic anhydrases - p. 91 13. 6 Plasmodium falciparum η-carbonic anhydrase - p. 113 14. 7 Trypanosoma cruzi and Leishmania spp. CAs - p. 129 15. 8 Toxoplasma gondii, babesia, and other protozoan carbonic anhydrases - p. 183 16. 9 Trichomonas vaginalis carbonic anhydrase - p. 207 17. 10 Entamoeba histolytica carbonic anhydrase - p. 219 18. 11 Challenges for developing selective fungal/protozoal carbonic anhydrase inhibitors as anti-infectives - p. 229
