G Protein-Coupled Receptors, Part B, Volume 195 represents the largest class of cell H103 surface proteins that have intricate involvement in nearly every physiological process in our body. Approximately one third of the clinically prescribed medicines target GPCRs and the quest to improve the exiting GPCR-targeting therapeutics continues. Sections in this volume include Adhesion G protein-coupled receptors: Structure and functions, Molecular and cellular mechanisms underlying brain region-specific cannabinoid receptor modulation by estradiol across the rodent estrus cycle, Probing the orphan receptors: Tools and directions, Asymmetric activation of Class C GPCRs, Common and selective signal transduction mechanisms of GPCRs, and much more.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Contributors - p. iii 6. Preface - p. iii 7. Chapter One: Adhesion G protein-coupled receptors—Structure and functions - p. 1 8. Chapter Two: Molecular and cellular mechanisms underlying brain region-specific endocannabinoid system modulation by estradiol across the rodent estrus cycle - p. 30 9. Chapter Three: Probing the orphan receptors: Tools and directions - p. 54 10. Chapter Four: Asymmetric activation of class C GPCRs - p. 77 11. Chapter Five: Common and selective signal transduction mechanisms of GPCRs - p. 89 12. Chapter Six: Appreciating the potential for GPCR crosstalk with ion channels - p. 101 13. Chapter Seven: Recent advances in calcium-sensing receptor structures and signaling pathways - p. 123 14. Chapter Eight: Structural insights into promiscuous GPCR-G protein coupling - p. 137 15. Chapter Nine: Opioid signaling and design of analgesics - p. 153 16. Index - p. 176
G Protein-Coupled Receptors, Part B, Volume 195 represents the largest class of cell H103 surface proteins that have intricate involvement in nearly every physiological process in our body. Approximately one third of the clinically prescribed medicines target GPCRs and the quest to improve the exiting GPCR-targeting therapeutics continues. Sections in this volume include Adhesion G protein-coupled receptors: Structure and functions, Molecular and cellular mechanisms underlying brain region-specific cannabinoid receptor modulation by estradiol across the rodent estrus cycle, Probing the orphan receptors: Tools and directions, Asymmetric activation of Class C GPCRs, Common and selective signal transduction mechanisms of GPCRs, and much more.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Contributors - p. iii 6. Preface - p. iii 7. Chapter One: Adhesion G protein-coupled receptors—Structure and functions - p. 1 8. Chapter Two: Molecular and cellular mechanisms underlying brain region-specific endocannabinoid system modulation by estradiol across the rodent estrus cycle - p. 30 9. Chapter Three: Probing the orphan receptors: Tools and directions - p. 54 10. Chapter Four: Asymmetric activation of class C GPCRs - p. 77 11. Chapter Five: Common and selective signal transduction mechanisms of GPCRs - p. 89 12. Chapter Six: Appreciating the potential for GPCR crosstalk with ion channels - p. 101 13. Chapter Seven: Recent advances in calcium-sensing receptor structures and signaling pathways - p. 123 14. Chapter Eight: Structural insights into promiscuous GPCR-G protein coupling - p. 137 15. Chapter Nine: Opioid signaling and design of analgesics - p. 153 16. Index - p. 176
