Cholinergic Involvement in Neurodegenerative Diseases, Volume 211 reviews cholinergic function in the brain as it relates to Neurodegenerative disorders. Coverage includes Alzheimer’s, dementia, Down Syndrome, Parkinson’s, Huntington’s, ALS, and more. In addition, the anatomy of the cholinergic system is described as well as the distribution and function of receptors.
1. Cholinergic Involvement in Neurodegenerative Diseases - p. i 2. Cover image - p. i 3. Title page - p. i 4. Table of Contents - p. i 5. Series Page - p. ii 6. Copyright - p. iv 7. Handbook of Clinical Neurology 3rd Series - p. v 8. Foreword - p. ix 9. Preface - p. xi 10. Contributors - p. xiii 11. Chapter 1 A brief history of the CNS cholinergic transmission - p. 1 12. Chapter 2 Organization of the basal forebrain cholinergic system in the human brain - p. 11 13. Chapter 3 The cholinergic synapses - p. 23 14. Chapter 4 Nicotinic acetylcholine receptors in the brain - p. 37 15. Chapter 5 Cognition and modulation of the cholinergic system - p. 55 16. Chapter 6 The involvement of the cholinergic system in Alzheimer disease - p. 63 17. Chapter 7 Structural changes to the basal forebrain cholinergic system in the continuum of Alzheimer disease - p. 81 18. Chapter 8 The dependence of basal forebrain cholinergic neurons on NGF: The case in Alzheimer pathology - p. 95 19. Chapter 9 NGF-based cholinergic therapies in Alzheimer disease - p. 123 20. Chapter 10 Memory network and cognitive reserve are associated with preserved and stimulated cholinergic neurotransmission - p. 137 21. Chapter 11 Cholinergic therapy in Alzheimer disease - p. 155 22. Chapter 12 CNS muscarinic receptors and muscarinic receptor agonists in Alzheimer disease treatment - p. 161 23. Chapter 13 The cholinotrophic system in Down syndrome - p. 185 24. Chapter 14 The involvement of the cholinergic system in Parkinson disease - p. 215 25. Chapter 15 The cholinergic system in dementia with Lewy bodies - p. 231 26. Chapter 16 Epilogue: Standing on the shoulders of giants—charting the future of cholinergic research - p. 247 27. Index - p. 249
Cholinergic Involvement in Neurodegenerative Diseases, Volume 211 reviews cholinergic function in the brain as it relates to Neurodegenerative disorders. Coverage includes Alzheimer’s, dementia, Down Syndrome, Parkinson’s, Huntington’s, ALS, and more. In addition, the anatomy of the cholinergic system is described as well as the distribution and function of receptors.
1. Cholinergic Involvement in Neurodegenerative Diseases - p. i 2. Cover image - p. i 3. Title page - p. i 4. Table of Contents - p. i 5. Series Page - p. ii 6. Copyright - p. iv 7. Handbook of Clinical Neurology 3rd Series - p. v 8. Foreword - p. ix 9. Preface - p. xi 10. Contributors - p. xiii 11. Chapter 1 A brief history of the CNS cholinergic transmission - p. 1 12. Chapter 2 Organization of the basal forebrain cholinergic system in the human brain - p. 11 13. Chapter 3 The cholinergic synapses - p. 23 14. Chapter 4 Nicotinic acetylcholine receptors in the brain - p. 37 15. Chapter 5 Cognition and modulation of the cholinergic system - p. 55 16. Chapter 6 The involvement of the cholinergic system in Alzheimer disease - p. 63 17. Chapter 7 Structural changes to the basal forebrain cholinergic system in the continuum of Alzheimer disease - p. 81 18. Chapter 8 The dependence of basal forebrain cholinergic neurons on NGF: The case in Alzheimer pathology - p. 95 19. Chapter 9 NGF-based cholinergic therapies in Alzheimer disease - p. 123 20. Chapter 10 Memory network and cognitive reserve are associated with preserved and stimulated cholinergic neurotransmission - p. 137 21. Chapter 11 Cholinergic therapy in Alzheimer disease - p. 155 22. Chapter 12 CNS muscarinic receptors and muscarinic receptor agonists in Alzheimer disease treatment - p. 161 23. Chapter 13 The cholinotrophic system in Down syndrome - p. 185 24. Chapter 14 The involvement of the cholinergic system in Parkinson disease - p. 215 25. Chapter 15 The cholinergic system in dementia with Lewy bodies - p. 231 26. Chapter 16 Epilogue: Standing on the shoulders of giants—charting the future of cholinergic research - p. 247 27. Index - p. 249
