Genetic Testing in Breast Cancer: Innovations in Diagnosis and Treatment addresses the urgent need for novel, minimally invasive diagnostic techniques to accurately identify breast cancer early and monitor treatment efficacy, focusing particularly on triple-negative breast cancer (TNBC). This comprehensive volume analyzes the latest research and developments in genetic testing, covering strategies like next-generation sequencing and the Sanger method. It highlights their potential to revolutionize early diagnosis and personalized treatment plans. The book also discusses challenges and opportunities, providing insights into hereditary mutations, genetic counseling, and clinical practice integration.
Serving as a valuable resource for students, researchers, oncologists, pharmacologists, and healthcare professionals, it includes preclinical and clinical case studies that illustrate the practical applications of genetic testing for various breast cancer subtypes, including TNBC and HER2-positive breast cancer. The editors aim to advance treatment and improve patient outcomes through cutting-edge genetic testing techniques.
1. Chapter 1 Introduction to breast cancer and genetic testing - p. xxix 2. Chapter 2 The genetic basis of breast cancer - p. 24 3. Chapter 3 Prognostic and predictive variables in early breast cancer genetic analysis - p. 43 4. Chapter 4 Genetic testing: An innovative approach to treat hereditary breast cancer - p. 63 5. Chapter 5 Overview of genetic testing techniques - p. 84 6. Chapter 6 Tools for breast cancer prediction and prognosis based on gene expression - p. 103 7. Chapter 7 Genetic risk assessment and screening - p. 120 8. Chapter 8 Genetic testing and personalized breast cancer treatment - p. 147 9. Chapter 9 Impact of genetic testing on prognosis and survival rates - p. 166 10. Chapter 10 Understanding the genetic test report - p. 181 11. Chapter 11 The role of genetic counseling in breast cancer - p. 199 12. Chapter 12 Genetics and clinical concerns related to breast cancer research - p. 216 13. Chapter 13 Empowerment and support after genetic testing - p. 258 14. Chapter 14 Ethical, legal, and social implications of genetic testing - p. 279 15. Chapter 15 Case studies in genetic testing and breast cancer treatment - p. 298 16. Chapter 16 Clinical applications of genetic testing in breast cancer diagnosis - p. 322 17. Chapter 17 Applications of AI and machine learning in breast cancer diagnosis and treatment - p. 336 18. Chapter 18 Emerging advancements in genetic research and testing - p. 355 19. Chapter 19 Integrative role of genetics and epigenetics in breast cancer - p. 370 20. Chapter 20 The potential for epigenetic-based therapies in breast cancer - p. 402 21. Index - p. 419
Genetic Testing in Breast Cancer: Innovations in Diagnosis and Treatment addresses the urgent need for novel, minimally invasive diagnostic techniques to accurately identify breast cancer early and monitor treatment efficacy, focusing particularly on triple-negative breast cancer (TNBC). This comprehensive volume analyzes the latest research and developments in genetic testing, covering strategies like next-generation sequencing and the Sanger method. It highlights their potential to revolutionize early diagnosis and personalized treatment plans. The book also discusses challenges and opportunities, providing insights into hereditary mutations, genetic counseling, and clinical practice integration.
Serving as a valuable resource for students, researchers, oncologists, pharmacologists, and healthcare professionals, it includes preclinical and clinical case studies that illustrate the practical applications of genetic testing for various breast cancer subtypes, including TNBC and HER2-positive breast cancer. The editors aim to advance treatment and improve patient outcomes through cutting-edge genetic testing techniques.
1. Chapter 1 Introduction to breast cancer and genetic testing - p. xxix 2. Chapter 2 The genetic basis of breast cancer - p. 24 3. Chapter 3 Prognostic and predictive variables in early breast cancer genetic analysis - p. 43 4. Chapter 4 Genetic testing: An innovative approach to treat hereditary breast cancer - p. 63 5. Chapter 5 Overview of genetic testing techniques - p. 84 6. Chapter 6 Tools for breast cancer prediction and prognosis based on gene expression - p. 103 7. Chapter 7 Genetic risk assessment and screening - p. 120 8. Chapter 8 Genetic testing and personalized breast cancer treatment - p. 147 9. Chapter 9 Impact of genetic testing on prognosis and survival rates - p. 166 10. Chapter 10 Understanding the genetic test report - p. 181 11. Chapter 11 The role of genetic counseling in breast cancer - p. 199 12. Chapter 12 Genetics and clinical concerns related to breast cancer research - p. 216 13. Chapter 13 Empowerment and support after genetic testing - p. 258 14. Chapter 14 Ethical, legal, and social implications of genetic testing - p. 279 15. Chapter 15 Case studies in genetic testing and breast cancer treatment - p. 298 16. Chapter 16 Clinical applications of genetic testing in breast cancer diagnosis - p. 322 17. Chapter 17 Applications of AI and machine learning in breast cancer diagnosis and treatment - p. 336 18. Chapter 18 Emerging advancements in genetic research and testing - p. 355 19. Chapter 19 Integrative role of genetics and epigenetics in breast cancer - p. 370 20. Chapter 20 The potential for epigenetic-based therapies in breast cancer - p. 402 21. Index - p. 419
