Gold Nanoparticles for Drug Delivery discusses the synthesis and characterization of gold nanoparticles (AuNPs), presenting an historical introduction to the developments in the area, discussing methods and characterization parameters, covering targeted delivery strategies, treatment of cancer, CNS conditions, infectious diseases, HIV/AIDS infection, wound healing and tissue regeneration, dentistry, gene delivery, and its photo properties used in diagnostic and therapies, and finally presenting regulatory aspects such as theranostic applications, vaccine development, toxicity, and the translation of research to marketable products.
This book is a complete reference for researchers in nanotechnology drug delivery and pharmaceutical disciplines. Researchers in pharmaceutical industries, especially those involved in the use of gold nanoparticles in the field of drug delivery, diagnosis, targeted and early therapies will also benefit from this book.
1. Chapter 1 : History, introduction, and physiochemical properties of gold nanoparticles - p. Page xiv 2. Chapter 2 : Green synthesis and characterization parameters of gold nanoparticles - p. Page 25 3. Chapter 3 : Cellular interactions and design principles of glyco-gold nanoparticles for drug delivery applications - p. Page 61 4. Chapter 4 : Targeting strategies using gold nanoparticles for efficient drug delivery - p. Page 106 5. Chapter 5 : Gold nanoparticles for delivery of nucleic acid constructs for cancer treatment - p. Page 136 6. Chapter 6 : Theranostic gold nanoparticle-assisted tumor radiosensitization and imaging - p. Page 162 7. Chapter 7 : Potential therapeutic role of gold nanoparticles in inflammatory diseases - p. Page 189 8. Chapter 8 : The use of gold nanoparticles in the treatment of neurodegenerative diseases - p. Page 219 9. Chapter 9 : Gold nanoparticles for treatment of cerebral diseases - p. Page 246 10. Chapter 10 : Gold nanoparticles for treatment of infectious diseases - p. Page 270 11. Chapter 11 : Gold nanoparticles as a recent nanocarrier against HIV/AIDS - p. Page 298 12. Chapter 12 : Gold nanoparticles in tissue engineering and regeneration - p. Page 324 13. Chapter 13 : Applications of gold nanoparticle in regenerative medicine - p. Page 348 14. Chapter 14 : Gold nanoparticles in photodynamic and photothermal therapy - p. Page 361 15. Chapter 15 : Polymeric gold nanoparticles for gene therapy - p. Page 385 16. Chapter 16 : Hybrid gold nanoparticles as advanced drug delivery and theranostics application - p. Page 414 17. Chapter 17 : Application of gold nanoparticles in vaccine development - p. Page 441 18. Chapter 18 : Clinical translation of gold nanoparticles: obstacles and perspectives - p. Page 486 19. Chapter 19 : Conclusion and future perspective of gold nanoparticles - p. Page 507 20. Index - p. Page 523
Gold Nanoparticles for Drug Delivery discusses the synthesis and characterization of gold nanoparticles (AuNPs), presenting an historical introduction to the developments in the area, discussing methods and characterization parameters, covering targeted delivery strategies, treatment of cancer, CNS conditions, infectious diseases, HIV/AIDS infection, wound healing and tissue regeneration, dentistry, gene delivery, and its photo properties used in diagnostic and therapies, and finally presenting regulatory aspects such as theranostic applications, vaccine development, toxicity, and the translation of research to marketable products.
This book is a complete reference for researchers in nanotechnology drug delivery and pharmaceutical disciplines. Researchers in pharmaceutical industries, especially those involved in the use of gold nanoparticles in the field of drug delivery, diagnosis, targeted and early therapies will also benefit from this book.
1. Chapter 1 : History, introduction, and physiochemical properties of gold nanoparticles - p. Page xiv 2. Chapter 2 : Green synthesis and characterization parameters of gold nanoparticles - p. Page 25 3. Chapter 3 : Cellular interactions and design principles of glyco-gold nanoparticles for drug delivery applications - p. Page 61 4. Chapter 4 : Targeting strategies using gold nanoparticles for efficient drug delivery - p. Page 106 5. Chapter 5 : Gold nanoparticles for delivery of nucleic acid constructs for cancer treatment - p. Page 136 6. Chapter 6 : Theranostic gold nanoparticle-assisted tumor radiosensitization and imaging - p. Page 162 7. Chapter 7 : Potential therapeutic role of gold nanoparticles in inflammatory diseases - p. Page 189 8. Chapter 8 : The use of gold nanoparticles in the treatment of neurodegenerative diseases - p. Page 219 9. Chapter 9 : Gold nanoparticles for treatment of cerebral diseases - p. Page 246 10. Chapter 10 : Gold nanoparticles for treatment of infectious diseases - p. Page 270 11. Chapter 11 : Gold nanoparticles as a recent nanocarrier against HIV/AIDS - p. Page 298 12. Chapter 12 : Gold nanoparticles in tissue engineering and regeneration - p. Page 324 13. Chapter 13 : Applications of gold nanoparticle in regenerative medicine - p. Page 348 14. Chapter 14 : Gold nanoparticles in photodynamic and photothermal therapy - p. Page 361 15. Chapter 15 : Polymeric gold nanoparticles for gene therapy - p. Page 385 16. Chapter 16 : Hybrid gold nanoparticles as advanced drug delivery and theranostics application - p. Page 414 17. Chapter 17 : Application of gold nanoparticles in vaccine development - p. Page 441 18. Chapter 18 : Clinical translation of gold nanoparticles: obstacles and perspectives - p. Page 486 19. Chapter 19 : Conclusion and future perspective of gold nanoparticles - p. Page 507 20. Index - p. Page 523
