With the improvements in formulation science and certain transdermal delivery technologies, the non-invasive mode of drug delivery is now ready to compete with traditional methods of oral and injectible routes of drug delivery. The Handbook of Non-Invasive Drug Delivery Systems encompasses the broad field of non-invasive drug delivery systems that include drug delivery via topical, transdermal-passive, transdermal-active (device- aided enhanced penetration), trans-mucosal membrane, trans-ocular membrane as well as delivery via alveolar membrane from inhaled medication. Patient compliance has been found to be much higher when administrated by non-invasive routes and therefore they are considered to be a preferred mode of drug delivery.
The book includes both science and technological aspects of new drug delivery systems. Its unique focus is that it is on new drug delivery systems that are considered to be "non-invasive". Other unique features include a chapter on Regulatory Aspects of non-invasive systems and one on FDA guidance for topical nano-drug delivery. Two chapters covering market trends and perspectives, as well as providing guidance to those marketing such systems are also included.
1. Cover image 2. Title page 3. Table of Contents 4. Copyright 5. Preface 6. List of Contributors 7. Part 1: Materials and Fabrication Methods 8. Chapter 1. Microfluidic Cell Culture Platforms with Embedded Nanoscale Features 9. Chapter 2. Microvascular Networks for Tissue Engineering 10. Chapter 3. Microfluidics for Engineering 3D Tissues and Cellular Microenvironments 11. Chapter 4. Fabrication of Advanced Microcontainer Arrays for Perfused 3D Cell Culture in Microfluidic Bioreactors 12. Chapter 5. Mechanobiological Approaches for the Control of Cell Motility 13. Chapter 6. Transport Models for Three-Dimensional Cell Culture Systems 14. Part 2: Tissue Engineering Strategies 15. Chapter 7. Microfluidic Systems for Controlling Stem Cells Microenvironments 16. Chapter 8. Vascularization of Microfluidic Hydrogels 17. Chapter 9. Microfluidic Vascular Networks for Engineered Tissues 18. Chapter 10. Microfluidic Approaches Toward Pulmonary Tissue Constructs 19. Chapter 11. Microfabricated Kidney Tissue Models 20. Chapter 12. Microfluidic Cell Culture Techniques 21. Part 3: In Vitro Models 22. Chapter 13. Functionalized Microfluidic Devices for Separation of Cell Phenotypes 23. Chapter 14. Microfluidic Hepatotoxicity Platform 24. Chapter 15. Live Cell Analysis Under Shear Flow 25. Chapter 16. Microfluidic Platforms for Evaluating Angiogenesis and Vasculogenesis 26. Chapter 17. Cardiovascular Disease/Discovery Models 27. Index
With the improvements in formulation science and certain transdermal delivery technologies, the non-invasive mode of drug delivery is now ready to compete with traditional methods of oral and injectible routes of drug delivery. The Handbook of Non-Invasive Drug Delivery Systems encompasses the broad field of non-invasive drug delivery systems that include drug delivery via topical, transdermal-passive, transdermal-active (device- aided enhanced penetration), trans-mucosal membrane, trans-ocular membrane as well as delivery via alveolar membrane from inhaled medication. Patient compliance has been found to be much higher when administrated by non-invasive routes and therefore they are considered to be a preferred mode of drug delivery.
The book includes both science and technological aspects of new drug delivery systems. Its unique focus is that it is on new drug delivery systems that are considered to be "non-invasive". Other unique features include a chapter on Regulatory Aspects of non-invasive systems and one on FDA guidance for topical nano-drug delivery. Two chapters covering market trends and perspectives, as well as providing guidance to those marketing such systems are also included.
1. Cover image 2. Title page 3. Table of Contents 4. Copyright 5. Preface 6. List of Contributors 7. Part 1: Materials and Fabrication Methods 8. Chapter 1. Microfluidic Cell Culture Platforms with Embedded Nanoscale Features 9. Chapter 2. Microvascular Networks for Tissue Engineering 10. Chapter 3. Microfluidics for Engineering 3D Tissues and Cellular Microenvironments 11. Chapter 4. Fabrication of Advanced Microcontainer Arrays for Perfused 3D Cell Culture in Microfluidic Bioreactors 12. Chapter 5. Mechanobiological Approaches for the Control of Cell Motility 13. Chapter 6. Transport Models for Three-Dimensional Cell Culture Systems 14. Part 2: Tissue Engineering Strategies 15. Chapter 7. Microfluidic Systems for Controlling Stem Cells Microenvironments 16. Chapter 8. Vascularization of Microfluidic Hydrogels 17. Chapter 9. Microfluidic Vascular Networks for Engineered Tissues 18. Chapter 10. Microfluidic Approaches Toward Pulmonary Tissue Constructs 19. Chapter 11. Microfabricated Kidney Tissue Models 20. Chapter 12. Microfluidic Cell Culture Techniques 21. Part 3: In Vitro Models 22. Chapter 13. Functionalized Microfluidic Devices for Separation of Cell Phenotypes 23. Chapter 14. Microfluidic Hepatotoxicity Platform 24. Chapter 15. Live Cell Analysis Under Shear Flow 25. Chapter 16. Microfluidic Platforms for Evaluating Angiogenesis and Vasculogenesis 26. Chapter 17. Cardiovascular Disease/Discovery Models 27. Index
