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Covering the broad range of benign and malignant disorders that affect the hematopoietic system, Hematopathology, 3rd Edition, remains your #1 source of authoritative information in this fast-changing field. Edited by Dr. Elaine Jaffe and a team of globally renowned, expert co-editors, it offers a wealth of up-to-date information in an easily accessible format, equipping you to deliver more accurate and actionable pathology reports. Comprehensive in scope, this highly illustrated, practical text is a must-have resource for residents and practicing pathologists alike.

  • Helps you navigate the latest changes in the classification of hematolymphoid neoplasms, providing guidance for use of both the International Consensus Classification (ICC) and 5th edition of the WHO classification.
  • Incorporates the latest molecular/cytogenetic information, regarding newly recognized entities and the latest diagnostic criteria.
  • Provides you with today's most effective guidance in evaluating specimens from the lymph nodes, bone marrow, peripheral blood, and more, with authoritative information on the pathogenesis, clinical and pathologic diagnosis, and treatment for each.
  • Details the latest insights on the molecular biology of benign and malignant hematologic disorders.
  • Features more than 1,100 high-quality color images that mirror the findings you encounter in practice.
  • Uses an easy-to-navigate, templated format with standard headings in each chapter.
  • Includes information on disease progression and prognosis, helping you better understand the clinical implications of diagnosis.
  • Shares the knowledge and expertise of new editors, Drs. Lisa Rimsza, Attilio Orazi, and Steven Swerdlow, providing expertise in molecular diagnostics, bone marrow and lymph node biopsies.

1. INTRODUCTION - p. 65 2. BIOLOGICAL AND TECHNOLOGIC ISSUES - p. 65 3. LYMPHOID NEOPLASMS - p. 77 4. MYELOID NEOPLASMS - p. 91 5. POTENTIAL PITFALLS OF MOLECULAR TESTING - p. 105 6. SUMMARY AND CONCLUSIONS - p. 107 7. Acknowledgments - p. 107 8. Pearls and Pitfalls - p. 107 9. Chapter 6. Important Chromosomal Aberrations in Hematologic Neoplasms and Key Techniques to Diagnose Them - p. 108 10. TYPES OF CHROMOSOMAL ABERRATIONS IN HEMATOLOGIC MALIGNANCIES - p. 108 11. CONVENTIONAL CYTOGENETIC METHODS - p. 111 12. MOLECULAR CYTOGENETIC METHODS - p. 112 13. CLINICAL RELEVANCE OF CHROMOSOMAL ABNORMALITIES IN HEMATOLOGIC MALIGNANCIES - p. 118 14. CONCLUSION - p. 132 15. Pearls and Pitfalls - p. 132 16. Acknowledgments - p. 132 17. Part II. Normal and Reactive Conditions of Hematopoietic Tissues - p. 133 18. Chapter 7. Normal Lymphoid Organs and Tissues - p. 135 19. Chapter 8. Reactive Lymphadenopathies - p. 159 20. Chapter 9. The Normal Bone Marrow - p. 185 21. Chapter 10. Evaluation of Anemia, Leukopenia, and Thrombocytopenia - p. 205 22. EVALUATION OF ANEMIA - p. 205 23. EVALUATION OF LEUKOPENIA - p. 228 24. EVALUATION OF THROMBOCYTOPENIA - p. 237 25. EVALUATION OF SPECIFIC BONE MARROW FAILURE SYNDROMES - p. 245 26. Pearls and Pitfalls - p. 249 27. Chapter 11. Bone Marrow Findings in Inflammatory, Infectious, and Metabolic Disorders - p. 250 28. Part III. Lymphoid Neoplasms - p. 267 29. Chapter 12. Principles of Classification of Lymphoid Neoplasms - p. 269 30. Section 1. MATURE B-CELL NEOPLASMS - p. 279.e3 31. Chapter 13. Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Monoclonal B-Cell Lymphocytosis, and B-Cell Prolymphocytic Leukemia - p. 280 32. Chapter 14. Lymphoplasmacytic Lymphoma and Waldenström Macroglobulinemia - p. 310 33. Chapter 15. Hairy Cell Leukemia - p. 327 34. Chapter 16. Splenic Marginal Zone Lymphoma and Other Small B-Cell Neoplasms in the Spleen - p. 338 35. Chapter 17. Follicular Lymphoma - p. 352 36. Chapter 18. Extranodal Marginal Zone Lymphoma: MALT Lymphoma - p. 383 37. Chapter 19. Primary Cutaneous B-Cell Lymphomas - p. 399 38. Chapter 20. Nodal Marginal Zone Lymphoma - p. 412 39. Chapter 21. Mantle Cell Lymphoma - p. 427 40. Chapter 22. Aggressive B-Cell Lymphomas Including Diffuse Large B-Cell Lymphoma, Not Otherwise Specified and Other Nodal and Extranodal Large B-Cell Lymphomas - p. 446 41. INTRODUCTION - p. 446 42. DEFINITIONS, SYNONYMS, AND TERMS - p. 446 43. DIFFUSE LARGE B-CELL LYMPHOMA, NOT OTHERWISE SPECIFIED - p. 446 44. T-CELL/HISTIOCYTE–RICH LARGE B-CELL LYMPHOMA - p. 468 45. PRIMARY MEDIASTINAL LARGE B-CELL LYMPHOMA - p. 472 46. INTRAVASCULAR LARGE B-CELL LYMPHOMA - p. 476 47. Pearls and Pitfalls - p. 479 48. Chapter 23. Burkitt Lymphoma, High-Grade B-Cell Lymphoma Not Otherwise Specified, High-Grade B-Cell Lymphoma With MYC and BCL2/BCL6 Rearrangements, Large B-Cell Lymphoma With 11q Aberration, and Provisional Entity High-Grade B-Cell Lymphoma With MYC and BCL6 Rearrangements - p. 482 49. Chapter 24. Plasmablastic Neoplasms Other Than Plasma Cell Myeloma - p. 499 50. Chapter 25. Plasma Cell Neoplasms - p. 507 51. Classification Of Plasma Cell Neoplasms - p. 507 52. Pathogenesis of Plasma Cell Neoplasms - p. 507 53. Multiple Myeloma - p. 509 54. Monoclonal Gammopathy Of Undetermined Significance - p. 527 55. Plasmacytoma - p. 530 56. Immunoglobulin Deposition Diseases - p. 534 57. Plasma Cell Neoplasms With Associated Paraneoplastic Syndrome - p. 539 58. Pearls and Pitfalls - p. 542 59. Chapter 26. Nodular Lymphocyte-Predominant B-Cell Lymphoma - p. 544 60. Chapter 27. Classic Hodgkin Lymphoma - p. 563 61. Chapter 28. Virally Associated B-Cell Lymphoproliferative Disease - p. 585 62. Section 2. MATURE T-CELL AND NK-CELL NEOPLASMS - p. 608.e8 63. Chapter 29. Epstein-Barr Virus–Associated T-Cell and Natural Killer–Cell Lymphoproliferative Disorders - p. 610 64. INTRODUCTION - p. 610 65. Epstein-Barr Virus–Associated Hemophagocytic Lymphohistiocytosis - p. 611 66. Chronic Active Epstein-Barr Virus Disease - p. 613 67. Severe Mosquito Bite Allergy - p. 616 68. Hydroa Vacciniforme Lymphoproliferative Disorder - p. 618 69. Systemic Epstein-Barr Virus–Positive T-Cell Lymphoma of Childhood - p. 620 70. Extranodal NK/T-Cell Lymphoma, Nasal Type - p. 624 71. Extranasal NK/T-Cell Lymphoma - p. 625 72. Aggressive Nk-Cell Leukemia - p. 634 73. Primary Nodal Epstein-Barr Virus–Positive T/Nk-Cell Lymphoma - p. 640 74. Pearls and Pitfalls - p. 642 75. Chapter 30. T-Cell and NK-Cell Large Granular Lymphocyte Proliferations - p. 644 76. Chapter 31. T-Cell Prolymphocytic Leukemia - p. 655 77. Chapter 32. Adult T-Cell Leukemia/Lymphoma - p. 663 78. Chapter 33. Hepatosplenic T-Cell Lymphoma - p. 675 79. Chapter 34. Peripheral T-Cell Lymphoma, Not Otherwise Specified - p. 685 80. Chapter 35. Follicular Helper T-Cell Lymphoma - p. 701 81. Chapter 36. Anaplastic Large Cell Lymphoma, ALK Positive and ALK Negative - p. 716 82. Chapter 37. Enteropathy-Associated T-Cell Lymphoma and Other Primary Intestinal T-Cell Lymphomas - p. 736 83. Chapter 38. Mycosis Fungoides and Sézary Syndrome - p. 758 84. Chapter 39. Primary Cutaneous CD30-Positive T-Cell Lymphoproliferative Disorders - p. 776 85. Chapter 40. Primary Cutaneous T-Cell Lymphomas: Rare Subtypes - p. 792 86. Section 3. PRECURSOR B-AND T-CELL NEOPLASMS - p. 805.e4 87. Chapter 41. Precursor B-Cell and T-Cell Neoplasms - p. 806 88. Chapter 42. Acute Leukemias of Ambiguous Lineage - p. 821 89. Part IV. Myeloid, Histiocytic, and Related Proliferations - p. 829 90. Chapter 43. Principles of Classification of Myeloid Neoplasms - p. 831 91. Chapter 44. The Myelodysplastic Syndromes - p. 840 92. Incidence - p. 840 93. Synonyms and Related Terms - p. 840 94. Clinical Features - p. 840 95. Laboratory Features - p. 841 96. Diagnosis - p. 849 97. Classification - p. 850 98. Differential Diagnosis - p. 860 99. Etiology and Pathogenesis - p. 865 100. Conclusion - p. 865 101. Pearls and Pitfalls - p. 866 102. Chapter 45. Myeloid and Hematologic Neoplasms With Germline Predisposition - p. 867 103. Chapter 46. Acute Myeloid Leukemia - p. 889 104. Chapter 47. Myeloproliferative Neoplasms - p. 916 105. Introduction - p. 916 106. Etiology and Pathogenesis - p. 917 107. Chronic Myeloid Leukemia (CML) - p. 920 108. Chronic Neutrophilic Leukemia (CNL) - p. 929 109. Classic Bcr::Abl1-Negative Myeloproliferative Neoplasms - p. 932 110. Essential Thrombocythemia (ET) - p. 933 111. Primary Myelofibrosis (PMF) - p. 938 112. Polycythemia Vera - p. 944 113. Chronic Eosinophilic Leukemia, Not Otherwise Specified (CEL, NOS) - p. 950 114. Myeloproliferative Neoplasms, Unclassifiable (MPN-U) - p. 951 115. Conclusion - p. 951 116. Acknowledgments - p. 952 117. Pearls and Pitfalls - p. 952 118. Chapter 48. Myelodysplastic/Myeloproliferative Neoplasms and Premalignant Conditions - p. 953 119. Chapter 49. Mastocytosis - p. 975 120. Chapter 50. Eosinophilia, Chronic Eosinophilic Leukemia, Not Otherwise Specified, and Myeloid/Lymphoid Neoplasms With Eosinophilia and Tyrosine Kinase Gene Fusions - p. 999 121. Chapter 51. Blastic Plasmacytoid Dendritic Cell Neoplasm - p. 1022 122. Chapter 52. Histiocytic and Dendritic Cell Proliferations—Systemic and Neoplastic - p. 1034 123. Non-Neoplastic Histiocytic Disorders - p. 1034 124. Histiocytic and Dendritic Cell Neoplasms - p. 1048 125. Acknowledgment - p. 1081 126. Pearls and Pitfalls - p. 1081 127. Part V. Immunodeficiency Disorders - p. 1083 128. Chapter 53. The Pathology of Primary Immunodeficiencies - p. 1085 129. Chapter 54. Iatrogenic Immunodeficiency-Associated Lymphoproliferative Disorders - p. 1104 130. Part VI. Site-Specific Issues in the Diagnosis of Lymphoma and Leukemia - p. 1123 131. Chapter 55. Bone Marrow Evaluation for Lymphoma - p. 1125 132. Chapter 56. Evaluation of the Bone Marrow After Therapy - p. 1158 133. Effects of Selected Therapies and Bone Marrow Transplantation - p. 1159 134. Acute Leukemia or Myelodysplastic Syndrome - p. 1163 135. Chronic Myeloid Leukemia - p. 1171 136. BCR::ABL1-Negative Myeloproliferative Neoplasms - p. 1175 137. Chronic Lymphoproliferative and Plasma Cell Disorders - p. 1177 138. Other Bone Marrow Changes after Therapy - p. 1181 139. Pearls and Pitfalls - p. 1186 140. Chapter 57. Non-hematopoietic Neoplasms and Other Lesions of the Bone Marrow and Lymph Nodes - p. 1188 141. Chapter 58. Spleen: Normal Architecture and Neoplastic and Non-neoplastic Lesions - p. 1210 142. Chapter 59. Diagnosis of Lymphoma in Extranodal Sites Other Than Skin - p. 1228 143. Lymphomas of Immune-Privileged Sites - p. 1228 144. Lymphoma of The Nervous System and Meninges - p. 1228 145. Ocular Adnexal Lymphoma - p. 1233 146. Lymphomas of Waldeyer’s Ring - p. 1235 147. Lymphomas of The Nasal Cavity and Paranasal Sinuses - p. 1236 148. Salivary Gland Lymphomas - p. 1237 149. Lymphomas of The Oral Cavity - p. 1238 150. Thyroid Lymphomas - p. 1239 151. Laryngeal Lymphomas - p. 1240 152. Pulmonary Lymphomas - p. 1241 153. Lymphomas of The Pleura and Pleural Cavity - p. 1242 154. Lymphomas of The Thymus - p. 1242 155. Cardiac Lymphomas - p. 1242 156. Lymphomas of The Breast - p. 1243 157. Gastrointestinal Lymphomas - p. 1246 158. Gastric Lymphoma - p. 1246 159. Small and Large Intestinal Lymphomas - p. 1247 160. Lymphomas of The Liver and Pancreatobiliary Tract - p. 1248 161. Adrenal Lymphomas - p. 1249 162. Urinary Tract Lymphomas - p. 1249 163. Male Genital Tract Lymphomas - p. 1251 164. Lymphomas of The Female Genital Tract - p. 1253 165. Lymphomas of Bone - p. 1255 166. Pearls and Pitfalls - p. 1257 167. Appendix A. The International Consensus Classification of Myeloid, Lymphoid, and Histiocytic Neoplasms - p. 1258 168. Index - p. 1261

Descripcion
Descripción

Covering the broad range of benign and malignant disorders that affect the hematopoietic system, Hematopathology, 3rd Edition, remains your #1 source of authoritative information in this fast-changing field. Edited by Dr. Elaine Jaffe and a team of globally renowned, expert co-editors, it offers a wealth of up-to-date information in an easily accessible format, equipping you to deliver more accurate and actionable pathology reports. Comprehensive in scope, this highly illustrated, practical text is a must-have resource for residents and practicing pathologists alike.

  • Helps you navigate the latest changes in the classification of hematolymphoid neoplasms, providing guidance for use of both the International Consensus Classification (ICC) and 5th edition of the WHO classification.
  • Incorporates the latest molecular/cytogenetic information, regarding newly recognized entities and the latest diagnostic criteria.
  • Provides you with today's most effective guidance in evaluating specimens from the lymph nodes, bone marrow, peripheral blood, and more, with authoritative information on the pathogenesis, clinical and pathologic diagnosis, and treatment for each.
  • Details the latest insights on the molecular biology of benign and malignant hematologic disorders.
  • Features more than 1,100 high-quality color images that mirror the findings you encounter in practice.
  • Uses an easy-to-navigate, templated format with standard headings in each chapter.
  • Includes information on disease progression and prognosis, helping you better understand the clinical implications of diagnosis.
  • Shares the knowledge and expertise of new editors, Drs. Lisa Rimsza, Attilio Orazi, and Steven Swerdlow, providing expertise in molecular diagnostics, bone marrow and lymph node biopsies.

1. INTRODUCTION - p. 65 2. BIOLOGICAL AND TECHNOLOGIC ISSUES - p. 65 3. LYMPHOID NEOPLASMS - p. 77 4. MYELOID NEOPLASMS - p. 91 5. POTENTIAL PITFALLS OF MOLECULAR TESTING - p. 105 6. SUMMARY AND CONCLUSIONS - p. 107 7. Acknowledgments - p. 107 8. Pearls and Pitfalls - p. 107 9. Chapter 6. Important Chromosomal Aberrations in Hematologic Neoplasms and Key Techniques to Diagnose Them - p. 108 10. TYPES OF CHROMOSOMAL ABERRATIONS IN HEMATOLOGIC MALIGNANCIES - p. 108 11. CONVENTIONAL CYTOGENETIC METHODS - p. 111 12. MOLECULAR CYTOGENETIC METHODS - p. 112 13. CLINICAL RELEVANCE OF CHROMOSOMAL ABNORMALITIES IN HEMATOLOGIC MALIGNANCIES - p. 118 14. CONCLUSION - p. 132 15. Pearls and Pitfalls - p. 132 16. Acknowledgments - p. 132 17. Part II. Normal and Reactive Conditions of Hematopoietic Tissues - p. 133 18. Chapter 7. Normal Lymphoid Organs and Tissues - p. 135 19. Chapter 8. Reactive Lymphadenopathies - p. 159 20. Chapter 9. The Normal Bone Marrow - p. 185 21. Chapter 10. Evaluation of Anemia, Leukopenia, and Thrombocytopenia - p. 205 22. EVALUATION OF ANEMIA - p. 205 23. EVALUATION OF LEUKOPENIA - p. 228 24. EVALUATION OF THROMBOCYTOPENIA - p. 237 25. EVALUATION OF SPECIFIC BONE MARROW FAILURE SYNDROMES - p. 245 26. Pearls and Pitfalls - p. 249 27. Chapter 11. Bone Marrow Findings in Inflammatory, Infectious, and Metabolic Disorders - p. 250 28. Part III. Lymphoid Neoplasms - p. 267 29. Chapter 12. Principles of Classification of Lymphoid Neoplasms - p. 269 30. Section 1. MATURE B-CELL NEOPLASMS - p. 279.e3 31. Chapter 13. Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Monoclonal B-Cell Lymphocytosis, and B-Cell Prolymphocytic Leukemia - p. 280 32. Chapter 14. Lymphoplasmacytic Lymphoma and Waldenström Macroglobulinemia - p. 310 33. Chapter 15. Hairy Cell Leukemia - p. 327 34. Chapter 16. Splenic Marginal Zone Lymphoma and Other Small B-Cell Neoplasms in the Spleen - p. 338 35. Chapter 17. Follicular Lymphoma - p. 352 36. Chapter 18. Extranodal Marginal Zone Lymphoma: MALT Lymphoma - p. 383 37. Chapter 19. Primary Cutaneous B-Cell Lymphomas - p. 399 38. Chapter 20. Nodal Marginal Zone Lymphoma - p. 412 39. Chapter 21. Mantle Cell Lymphoma - p. 427 40. Chapter 22. Aggressive B-Cell Lymphomas Including Diffuse Large B-Cell Lymphoma, Not Otherwise Specified and Other Nodal and Extranodal Large B-Cell Lymphomas - p. 446 41. INTRODUCTION - p. 446 42. DEFINITIONS, SYNONYMS, AND TERMS - p. 446 43. DIFFUSE LARGE B-CELL LYMPHOMA, NOT OTHERWISE SPECIFIED - p. 446 44. T-CELL/HISTIOCYTE–RICH LARGE B-CELL LYMPHOMA - p. 468 45. PRIMARY MEDIASTINAL LARGE B-CELL LYMPHOMA - p. 472 46. INTRAVASCULAR LARGE B-CELL LYMPHOMA - p. 476 47. Pearls and Pitfalls - p. 479 48. Chapter 23. Burkitt Lymphoma, High-Grade B-Cell Lymphoma Not Otherwise Specified, High-Grade B-Cell Lymphoma With MYC and BCL2/BCL6 Rearrangements, Large B-Cell Lymphoma With 11q Aberration, and Provisional Entity High-Grade B-Cell Lymphoma With MYC and BCL6 Rearrangements - p. 482 49. Chapter 24. Plasmablastic Neoplasms Other Than Plasma Cell Myeloma - p. 499 50. Chapter 25. Plasma Cell Neoplasms - p. 507 51. Classification Of Plasma Cell Neoplasms - p. 507 52. Pathogenesis of Plasma Cell Neoplasms - p. 507 53. Multiple Myeloma - p. 509 54. Monoclonal Gammopathy Of Undetermined Significance - p. 527 55. Plasmacytoma - p. 530 56. Immunoglobulin Deposition Diseases - p. 534 57. Plasma Cell Neoplasms With Associated Paraneoplastic Syndrome - p. 539 58. Pearls and Pitfalls - p. 542 59. Chapter 26. Nodular Lymphocyte-Predominant B-Cell Lymphoma - p. 544 60. Chapter 27. Classic Hodgkin Lymphoma - p. 563 61. Chapter 28. Virally Associated B-Cell Lymphoproliferative Disease - p. 585 62. Section 2. MATURE T-CELL AND NK-CELL NEOPLASMS - p. 608.e8 63. Chapter 29. Epstein-Barr Virus–Associated T-Cell and Natural Killer–Cell Lymphoproliferative Disorders - p. 610 64. INTRODUCTION - p. 610 65. Epstein-Barr Virus–Associated Hemophagocytic Lymphohistiocytosis - p. 611 66. Chronic Active Epstein-Barr Virus Disease - p. 613 67. Severe Mosquito Bite Allergy - p. 616 68. Hydroa Vacciniforme Lymphoproliferative Disorder - p. 618 69. Systemic Epstein-Barr Virus–Positive T-Cell Lymphoma of Childhood - p. 620 70. Extranodal NK/T-Cell Lymphoma, Nasal Type - p. 624 71. Extranasal NK/T-Cell Lymphoma - p. 625 72. Aggressive Nk-Cell Leukemia - p. 634 73. Primary Nodal Epstein-Barr Virus–Positive T/Nk-Cell Lymphoma - p. 640 74. Pearls and Pitfalls - p. 642 75. Chapter 30. T-Cell and NK-Cell Large Granular Lymphocyte Proliferations - p. 644 76. Chapter 31. T-Cell Prolymphocytic Leukemia - p. 655 77. Chapter 32. Adult T-Cell Leukemia/Lymphoma - p. 663 78. Chapter 33. Hepatosplenic T-Cell Lymphoma - p. 675 79. Chapter 34. Peripheral T-Cell Lymphoma, Not Otherwise Specified - p. 685 80. Chapter 35. Follicular Helper T-Cell Lymphoma - p. 701 81. Chapter 36. Anaplastic Large Cell Lymphoma, ALK Positive and ALK Negative - p. 716 82. Chapter 37. Enteropathy-Associated T-Cell Lymphoma and Other Primary Intestinal T-Cell Lymphomas - p. 736 83. Chapter 38. Mycosis Fungoides and Sézary Syndrome - p. 758 84. Chapter 39. Primary Cutaneous CD30-Positive T-Cell Lymphoproliferative Disorders - p. 776 85. Chapter 40. Primary Cutaneous T-Cell Lymphomas: Rare Subtypes - p. 792 86. Section 3. PRECURSOR B-AND T-CELL NEOPLASMS - p. 805.e4 87. Chapter 41. Precursor B-Cell and T-Cell Neoplasms - p. 806 88. Chapter 42. Acute Leukemias of Ambiguous Lineage - p. 821 89. Part IV. Myeloid, Histiocytic, and Related Proliferations - p. 829 90. Chapter 43. Principles of Classification of Myeloid Neoplasms - p. 831 91. Chapter 44. The Myelodysplastic Syndromes - p. 840 92. Incidence - p. 840 93. Synonyms and Related Terms - p. 840 94. Clinical Features - p. 840 95. Laboratory Features - p. 841 96. Diagnosis - p. 849 97. Classification - p. 850 98. Differential Diagnosis - p. 860 99. Etiology and Pathogenesis - p. 865 100. Conclusion - p. 865 101. Pearls and Pitfalls - p. 866 102. Chapter 45. Myeloid and Hematologic Neoplasms With Germline Predisposition - p. 867 103. Chapter 46. Acute Myeloid Leukemia - p. 889 104. Chapter 47. Myeloproliferative Neoplasms - p. 916 105. Introduction - p. 916 106. Etiology and Pathogenesis - p. 917 107. Chronic Myeloid Leukemia (CML) - p. 920 108. Chronic Neutrophilic Leukemia (CNL) - p. 929 109. Classic Bcr::Abl1-Negative Myeloproliferative Neoplasms - p. 932 110. Essential Thrombocythemia (ET) - p. 933 111. Primary Myelofibrosis (PMF) - p. 938 112. Polycythemia Vera - p. 944 113. Chronic Eosinophilic Leukemia, Not Otherwise Specified (CEL, NOS) - p. 950 114. Myeloproliferative Neoplasms, Unclassifiable (MPN-U) - p. 951 115. Conclusion - p. 951 116. Acknowledgments - p. 952 117. Pearls and Pitfalls - p. 952 118. Chapter 48. Myelodysplastic/Myeloproliferative Neoplasms and Premalignant Conditions - p. 953 119. Chapter 49. Mastocytosis - p. 975 120. Chapter 50. Eosinophilia, Chronic Eosinophilic Leukemia, Not Otherwise Specified, and Myeloid/Lymphoid Neoplasms With Eosinophilia and Tyrosine Kinase Gene Fusions - p. 999 121. Chapter 51. Blastic Plasmacytoid Dendritic Cell Neoplasm - p. 1022 122. Chapter 52. Histiocytic and Dendritic Cell Proliferations—Systemic and Neoplastic - p. 1034 123. Non-Neoplastic Histiocytic Disorders - p. 1034 124. Histiocytic and Dendritic Cell Neoplasms - p. 1048 125. Acknowledgment - p. 1081 126. Pearls and Pitfalls - p. 1081 127. Part V. Immunodeficiency Disorders - p. 1083 128. Chapter 53. The Pathology of Primary Immunodeficiencies - p. 1085 129. Chapter 54. Iatrogenic Immunodeficiency-Associated Lymphoproliferative Disorders - p. 1104 130. Part VI. Site-Specific Issues in the Diagnosis of Lymphoma and Leukemia - p. 1123 131. Chapter 55. Bone Marrow Evaluation for Lymphoma - p. 1125 132. Chapter 56. Evaluation of the Bone Marrow After Therapy - p. 1158 133. Effects of Selected Therapies and Bone Marrow Transplantation - p. 1159 134. Acute Leukemia or Myelodysplastic Syndrome - p. 1163 135. Chronic Myeloid Leukemia - p. 1171 136. BCR::ABL1-Negative Myeloproliferative Neoplasms - p. 1175 137. Chronic Lymphoproliferative and Plasma Cell Disorders - p. 1177 138. Other Bone Marrow Changes after Therapy - p. 1181 139. Pearls and Pitfalls - p. 1186 140. Chapter 57. Non-hematopoietic Neoplasms and Other Lesions of the Bone Marrow and Lymph Nodes - p. 1188 141. Chapter 58. Spleen: Normal Architecture and Neoplastic and Non-neoplastic Lesions - p. 1210 142. Chapter 59. Diagnosis of Lymphoma in Extranodal Sites Other Than Skin - p. 1228 143. Lymphomas of Immune-Privileged Sites - p. 1228 144. Lymphoma of The Nervous System and Meninges - p. 1228 145. Ocular Adnexal Lymphoma - p. 1233 146. Lymphomas of Waldeyer’s Ring - p. 1235 147. Lymphomas of The Nasal Cavity and Paranasal Sinuses - p. 1236 148. Salivary Gland Lymphomas - p. 1237 149. Lymphomas of The Oral Cavity - p. 1238 150. Thyroid Lymphomas - p. 1239 151. Laryngeal Lymphomas - p. 1240 152. Pulmonary Lymphomas - p. 1241 153. Lymphomas of The Pleura and Pleural Cavity - p. 1242 154. Lymphomas of The Thymus - p. 1242 155. Cardiac Lymphomas - p. 1242 156. Lymphomas of The Breast - p. 1243 157. Gastrointestinal Lymphomas - p. 1246 158. Gastric Lymphoma - p. 1246 159. Small and Large Intestinal Lymphomas - p. 1247 160. Lymphomas of The Liver and Pancreatobiliary Tract - p. 1248 161. Adrenal Lymphomas - p. 1249 162. Urinary Tract Lymphomas - p. 1249 163. Male Genital Tract Lymphomas - p. 1251 164. Lymphomas of The Female Genital Tract - p. 1253 165. Lymphomas of Bone - p. 1255 166. Pearls and Pitfalls - p. 1257 167. Appendix A. The International Consensus Classification of Myeloid, Lymphoid, and Histiocytic Neoplasms - p. 1258 168. Index - p. 1261

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Ficha Técnica