Human Aging: From Cellular Mechanisms to Therapeutic Strategies offers an exhaustive picture of all the biological aspects of human aging by describing the key mechanisms associated with human aging and covering events that could disrupt the normal course of aging. Each chapter includes a summary of the salient points covered, along with futures prospects. The book provides readers with the information they need to gain or deepen the skills needed to evaluate the mechanisms of aging and age-related diseases and to monitor the effectiveness of therapies aimed at slowing aging.
The book encourages PhD and Postdoc students, researchers, health professionals and others interested in the biology of aging to explore the fascinating and challenging questions about why and how we age as well as what can and cannot be done about it.
1. Chapter 3. Pathobiology of aging: An introduction to age-related diseases - p. 35 2. Chapter 4. Cellular senescence and senescence-associated secretory phenotype (SASP) in aging process - p. 75 3. Chapter 5. The role of inflammaging in the development of chronic diseases of older people - p. 89 4. Chapter 6. A new perspective on ROS in aging with an integrated view of the gut microbiota - p. 105 5. Chapter 7. Aging of immune system - p. 113 6. Chapter 8. Vaccination in old age: Challenges and promises - p. 131 7. Chapter 9. Resilience signaling and hormesis in brain health and disease - p. 155 8. Chapter 10. Different components of frailty in the aging subjects—The role of sarcopenia - p. 175 9. Chapter 11. Hormones in aging - p. 207 10. Chapter 12. Chronobiology and chrononutrition: Relevance for aging - p. 219 11. Chapter 13. Nutraceutical approach to age-related diseases—The clinical evidence on cognitive decline - p. 255 12. Chapter 14. Ways to become old: Role of lifestyle in modulation of the hallmarks of aging - p. 273 13. Chapter 15. Nutritional biomarkers in aging research - p. 295 14. Chapter 16. The role of cytomegalovirus in organismal and immune aging - p. 319 15. Chapter 17. Ethics of aging - p. 329 16. Chapter 18. Conclusions. Slowing aging and fighting age-related diseases, from bench to bedside? - p. 341 17. Index - p. 355
Human Aging: From Cellular Mechanisms to Therapeutic Strategies offers an exhaustive picture of all the biological aspects of human aging by describing the key mechanisms associated with human aging and covering events that could disrupt the normal course of aging. Each chapter includes a summary of the salient points covered, along with futures prospects. The book provides readers with the information they need to gain or deepen the skills needed to evaluate the mechanisms of aging and age-related diseases and to monitor the effectiveness of therapies aimed at slowing aging.
The book encourages PhD and Postdoc students, researchers, health professionals and others interested in the biology of aging to explore the fascinating and challenging questions about why and how we age as well as what can and cannot be done about it.
1. Chapter 3. Pathobiology of aging: An introduction to age-related diseases - p. 35 2. Chapter 4. Cellular senescence and senescence-associated secretory phenotype (SASP) in aging process - p. 75 3. Chapter 5. The role of inflammaging in the development of chronic diseases of older people - p. 89 4. Chapter 6. A new perspective on ROS in aging with an integrated view of the gut microbiota - p. 105 5. Chapter 7. Aging of immune system - p. 113 6. Chapter 8. Vaccination in old age: Challenges and promises - p. 131 7. Chapter 9. Resilience signaling and hormesis in brain health and disease - p. 155 8. Chapter 10. Different components of frailty in the aging subjects—The role of sarcopenia - p. 175 9. Chapter 11. Hormones in aging - p. 207 10. Chapter 12. Chronobiology and chrononutrition: Relevance for aging - p. 219 11. Chapter 13. Nutraceutical approach to age-related diseases—The clinical evidence on cognitive decline - p. 255 12. Chapter 14. Ways to become old: Role of lifestyle in modulation of the hallmarks of aging - p. 273 13. Chapter 15. Nutritional biomarkers in aging research - p. 295 14. Chapter 16. The role of cytomegalovirus in organismal and immune aging - p. 319 15. Chapter 17. Ethics of aging - p. 329 16. Chapter 18. Conclusions. Slowing aging and fighting age-related diseases, from bench to bedside? - p. 341 17. Index - p. 355
