Immunology, Volume 1: Immunotoxicology, Immunopathology, and Immunotherapy discusses the investment of time, effort and finance that go into making progress in preventing and/or curing serious diseases by using standard treatments (chemotherapy, radiotherapy, surgery, and hormone therapy). The use of these treatments is accompanied by unavoidable, devastating side effects. At the cost of being repetitious, it has to be emphasized that an improved understanding of the immune system, avoidance of unhealthy habits (e.g., smoking, intake of alcohol, perpetual stress, and lack of exercise) and early detection (using biomarkers) are the only three friends we have to at least delay the onset of serious diseases.
1. Chapter 1. Introduction to Immunology - p. 3 2. Chapter 2. Cytomegalovirus and Autophagy - p. 9 3. Chapter 3. The Role of Macroautophagy in T Cells - p. 23 4. Chapter 4. Increased Immunogenicity Through Autophagy - p. 35 5. Chapter 5. Regulation of Humoral Immunity by CD1d-Restricted Natural Killer T Cells - p. 55 6. Chapter 6. Signaling by the Toll-Like Receptors Induces Autophagy Through Modification of Beclin 1: Molecular Mechanism - p. 75 7. Chapter 7. Molecular Mechanisms Underlying the Action of Ipilimumab Against Metastatic Melanoma - p. 85 8. Chapter 8. To Help or To Harm: Dynamic Roles of CD4+ T Helper Cells in Solid Tumor Microenvironments - p. 97 9. Chapter 9. Development and Function of Natural Killer Cells and Its Importance in Cancer Immunotherapy - p. 117 10. Part II: Role in Disease and Treatment - p. 134 11. Chapter 10. Varicella Zoster Vaccine Experience in HIV-Infected Children and Adolescents - p. 143 12. Chapter 11. Development of an Effective Alzheimer’s Vaccine - p. 149 13. Chapter 12. Obesity-Induced Defects in Dendritic Cell and T Cell Functions: Implications for Immunotherapeutic Efficacy in Cancer - p. 171 14. Chapter 13. Redox-Dependent Circuits Regulating B Lymphocyte Physiology - p. 183 15. Chapter 14. Immunomodulatory Attributes of Aged Garlic Extract and Its Components - p. 203 16. Chapter 15. MUC1 and Cancer Immunotherapy - p. 225 17. Index - p. 241
Immunology, Volume 1: Immunotoxicology, Immunopathology, and Immunotherapy discusses the investment of time, effort and finance that go into making progress in preventing and/or curing serious diseases by using standard treatments (chemotherapy, radiotherapy, surgery, and hormone therapy). The use of these treatments is accompanied by unavoidable, devastating side effects. At the cost of being repetitious, it has to be emphasized that an improved understanding of the immune system, avoidance of unhealthy habits (e.g., smoking, intake of alcohol, perpetual stress, and lack of exercise) and early detection (using biomarkers) are the only three friends we have to at least delay the onset of serious diseases.
1. Chapter 1. Introduction to Immunology - p. 3 2. Chapter 2. Cytomegalovirus and Autophagy - p. 9 3. Chapter 3. The Role of Macroautophagy in T Cells - p. 23 4. Chapter 4. Increased Immunogenicity Through Autophagy - p. 35 5. Chapter 5. Regulation of Humoral Immunity by CD1d-Restricted Natural Killer T Cells - p. 55 6. Chapter 6. Signaling by the Toll-Like Receptors Induces Autophagy Through Modification of Beclin 1: Molecular Mechanism - p. 75 7. Chapter 7. Molecular Mechanisms Underlying the Action of Ipilimumab Against Metastatic Melanoma - p. 85 8. Chapter 8. To Help or To Harm: Dynamic Roles of CD4+ T Helper Cells in Solid Tumor Microenvironments - p. 97 9. Chapter 9. Development and Function of Natural Killer Cells and Its Importance in Cancer Immunotherapy - p. 117 10. Part II: Role in Disease and Treatment - p. 134 11. Chapter 10. Varicella Zoster Vaccine Experience in HIV-Infected Children and Adolescents - p. 143 12. Chapter 11. Development of an Effective Alzheimer’s Vaccine - p. 149 13. Chapter 12. Obesity-Induced Defects in Dendritic Cell and T Cell Functions: Implications for Immunotherapeutic Efficacy in Cancer - p. 171 14. Chapter 13. Redox-Dependent Circuits Regulating B Lymphocyte Physiology - p. 183 15. Chapter 14. Immunomodulatory Attributes of Aged Garlic Extract and Its Components - p. 203 16. Chapter 15. MUC1 and Cancer Immunotherapy - p. 225 17. Index - p. 241
