Building on a solid foundation of knowledge and skills, this classic text from trusted author Mary Louise Turgeon clearly explains everything from basic immunologic mechanisms and serologic concepts to the theory behind procedures performed in the lab.This go-to resource prepares you for everything from mastering automated techniques to understanding immunoassay instrumentation and disorders of infectious and immunologic origin. Packed with learning objectives, review questions, step-by-step procedures, and case studies, this text is the key to your success in today’s modern laboratory environment.
1. Cover image - p. iii 2. Title page - p. iii 3. Table of Contents - p. iii 4. Quick Reference - p. i 5. Quick Reference—cont’d - p. ii 6. Copyright - p. iv 7. Dedication - p. v 8. Reviewers - p. vi 9. Preface - p. vii 10. About the Author - p. x 11. PART I. Basic Immunologic Mechanisms - p. P1 12. 1. Highlights of Innate and Adaptive Immune Systems - p. 2 13. 2. Soluble Mediators of the Immune System - p. 27 14. 3. Antigens and Antibodies - p. 46 15. 4. Cellular Activities and Clinical Disorders of Innate and Adaptive Immunity - p. 66 16. PART II. The Theory of Immunologic and Serologic Procedures - p. P2 17. 5. Basic Safety in the Immunology-Serology Laboratory - p. 98 18. 6. Basic Quality Control and Quality Assurance Practices - p. 106 19. 7. Basic Serologic Laboratory: Techniques and Clinical Applications - p. 116 20. 8. Precipitation and Particle Agglutination Methods - p. 130 21. 9. Electrophoresis Techniques and Chromatography - p. 146 22. 10. Labeling Techniques in Immunoassay - p. 153 23. 11. Flow Cytometry - p. 163 24. 12. Molecular Laboratory Techniques - p. 172 25. PART III. Immunologic Manifestations of Infectious Diseases - p. P3 26. 13. Infectious Diseases: Overview and TORCH Diseases - p. 193 27. 14. Streptococcal Infections - p. 225 28. 15. Syphilis - p. 233 29. 16. Vector-Borne Diseases - p. 246 30. 17. Infectious Mononucleosis - p. 264 31. 18. Viral Hepatitis - p. 271 32. PART IV. Immune Disorders - p. P4 33. 19. Primary and Acquired Immunodeficiency Syndromes - p. 298 34. 20. Hypersensitivity Reactions - p. 338 35. 21. Immunoproliferative Disorders - p. 355 36. 22. Tolerance, Autoimmunity, and Autoimmune Disorders - p. 369 37. 23. Systemic Lupus Erythematosus - p. 396 38. 24. Rheumatoid Arthritis - p. 415 39. PART V. Transplantation & Tumor Immunology - p. P5 40. 25. Transplantation: Human Leukocyte Antigens, Solid Organ, and Hematopoietic Stem Cells - p. 429 41. 26. Tumor Immunology and Applications of Massive Parallel Sequencing/Next-Generation Sequencing - p. 456 42. PART VI. Vaccines - p. P6 43. 27. Primer on Vaccines - p. 480 44. Appendix A. Answers to Case Study Multiple Choice Questions - p. 502 45. Appendix B. Answers to Review Questions - p. 505 46. Appendix C. Origin and Immunoregulatory Activity of Cytokines - p. 508 47. Appendix D. Coronavirus Disease 2019 (COVID-19) - p. 512 48. Appendix E. Vaccines Licensed in the United States by the Federal Drug Administration - p. 514 49. Bibliography - p. 516 50. Glossary - p. 528 51. Index - p. 550
Building on a solid foundation of knowledge and skills, this classic text from trusted author Mary Louise Turgeon clearly explains everything from basic immunologic mechanisms and serologic concepts to the theory behind procedures performed in the lab.This go-to resource prepares you for everything from mastering automated techniques to understanding immunoassay instrumentation and disorders of infectious and immunologic origin. Packed with learning objectives, review questions, step-by-step procedures, and case studies, this text is the key to your success in today’s modern laboratory environment.
1. Cover image - p. iii 2. Title page - p. iii 3. Table of Contents - p. iii 4. Quick Reference - p. i 5. Quick Reference—cont’d - p. ii 6. Copyright - p. iv 7. Dedication - p. v 8. Reviewers - p. vi 9. Preface - p. vii 10. About the Author - p. x 11. PART I. Basic Immunologic Mechanisms - p. P1 12. 1. Highlights of Innate and Adaptive Immune Systems - p. 2 13. 2. Soluble Mediators of the Immune System - p. 27 14. 3. Antigens and Antibodies - p. 46 15. 4. Cellular Activities and Clinical Disorders of Innate and Adaptive Immunity - p. 66 16. PART II. The Theory of Immunologic and Serologic Procedures - p. P2 17. 5. Basic Safety in the Immunology-Serology Laboratory - p. 98 18. 6. Basic Quality Control and Quality Assurance Practices - p. 106 19. 7. Basic Serologic Laboratory: Techniques and Clinical Applications - p. 116 20. 8. Precipitation and Particle Agglutination Methods - p. 130 21. 9. Electrophoresis Techniques and Chromatography - p. 146 22. 10. Labeling Techniques in Immunoassay - p. 153 23. 11. Flow Cytometry - p. 163 24. 12. Molecular Laboratory Techniques - p. 172 25. PART III. Immunologic Manifestations of Infectious Diseases - p. P3 26. 13. Infectious Diseases: Overview and TORCH Diseases - p. 193 27. 14. Streptococcal Infections - p. 225 28. 15. Syphilis - p. 233 29. 16. Vector-Borne Diseases - p. 246 30. 17. Infectious Mononucleosis - p. 264 31. 18. Viral Hepatitis - p. 271 32. PART IV. Immune Disorders - p. P4 33. 19. Primary and Acquired Immunodeficiency Syndromes - p. 298 34. 20. Hypersensitivity Reactions - p. 338 35. 21. Immunoproliferative Disorders - p. 355 36. 22. Tolerance, Autoimmunity, and Autoimmune Disorders - p. 369 37. 23. Systemic Lupus Erythematosus - p. 396 38. 24. Rheumatoid Arthritis - p. 415 39. PART V. Transplantation & Tumor Immunology - p. P5 40. 25. Transplantation: Human Leukocyte Antigens, Solid Organ, and Hematopoietic Stem Cells - p. 429 41. 26. Tumor Immunology and Applications of Massive Parallel Sequencing/Next-Generation Sequencing - p. 456 42. PART VI. Vaccines - p. P6 43. 27. Primer on Vaccines - p. 480 44. Appendix A. Answers to Case Study Multiple Choice Questions - p. 502 45. Appendix B. Answers to Review Questions - p. 505 46. Appendix C. Origin and Immunoregulatory Activity of Cytokines - p. 508 47. Appendix D. Coronavirus Disease 2019 (COVID-19) - p. 512 48. Appendix E. Vaccines Licensed in the United States by the Federal Drug Administration - p. 514 49. Bibliography - p. 516 50. Glossary - p. 528 51. Index - p. 550
