Immunology for Medical Students provides concise yet comprehensive information for medical students about the basic science of the human immune system, and how to apply this to clinical practice.
The book provides a detailed overview of how the immune system works, covers physiology, innate and adaptive immunity and the immune system in health and disease. Readers will learn how to assess a patient with an immune problem and understand from first principles the diagnosis and management of immune disorders.
This popular book is an ideal companion for medical school courses and has been fully updated to include the latest science on immunotherapies.
1. Section 1: Introduction - p. 1 2. 1. Introduction to the Immune System - p. 2 3. 2. Basic Concepts and Components of the Immune System - p. 7 4. Section 2: Antigen-Recognition Molecules - p. 15 5. 3. Introduction to Antigen Recognition - p. 16 6. 4. Antigens and Antibody Structure - p. 20 7. 5. Antibody-Antigen Interaction - p. 27 8. 6. Antibody Diversity - p. 37 9. 7. The T-Cell Receptor - p. 47 10. 8. Major Histocompatibility Complex - p. 54 11. 9. Review of Antigen Recognition - p. 62 12. Section 3: Physiology - p. 65 13. 10. Antigen Processing and Presentation - p. 66 14. 11. Lymphocyte Activation - p. 72 15. 12. Hematopoiesis - p. 80 16. 13. Organs and Tissues of the Immune System - p. 86 17. 14. B-Cell Development - p. 96 18. 15. T-Cell Development - p. 103 19. 16. T-Cell Interactions and T-Cell Help - p. 113 20. 17. Immunologic Memory and Homeostasis - p. 124 21. 18. Regulation of the Immune System - p. 130 22. 19. Brief Review of Immune Physiology - p. 136 23. Section 4: Innate Immunity - p. 140 24. 20. Constitutive Defenses Including Complement - p. 141 25. 21. Phagocytes - p. 152 26. 22. Killing in the Immune System - p. 164 27. 23. Inflammation - p. 174 28. 24. Cytokines in the Immune System - p. 184 29. Section 5: Immune System in Health and Disease - p. 192 30. 25. Infections and Vaccines - p. 193 31. 26. Hypersensitivity Reactions - p. 202 32. 27. Immediate Hypersensitivity (Type I): Allergy - p. 208 33. 28. How Autoimmune Disease Develops - p. 219 34. 29. Antibody-Mediated Hypersensitivity (Type II) - p. 233 35. 30. Immune Complex Disease (Type III Hypersensitivity) - p. 240 36. 31. Delayed Hypersensitivity (Type IV) and Review of Hypersensitivity Reactions - p. 247 37. 32. Primary Immunodeficiency - p. 255 38. 33. Secondary Immunodeficiency - p. 265 39. 34. Transplantation - p. 274 40. 35. Tumor Immunology - p. 284 41. 36. Biopharmaceuticals - p. 294 42. Glossary - p. 303 43. Index - p. 307 44. Confidence is ClinicalKey - p. 314
Immunology for Medical Students provides concise yet comprehensive information for medical students about the basic science of the human immune system, and how to apply this to clinical practice.
The book provides a detailed overview of how the immune system works, covers physiology, innate and adaptive immunity and the immune system in health and disease. Readers will learn how to assess a patient with an immune problem and understand from first principles the diagnosis and management of immune disorders.
This popular book is an ideal companion for medical school courses and has been fully updated to include the latest science on immunotherapies.
1. Section 1: Introduction - p. 1 2. 1. Introduction to the Immune System - p. 2 3. 2. Basic Concepts and Components of the Immune System - p. 7 4. Section 2: Antigen-Recognition Molecules - p. 15 5. 3. Introduction to Antigen Recognition - p. 16 6. 4. Antigens and Antibody Structure - p. 20 7. 5. Antibody-Antigen Interaction - p. 27 8. 6. Antibody Diversity - p. 37 9. 7. The T-Cell Receptor - p. 47 10. 8. Major Histocompatibility Complex - p. 54 11. 9. Review of Antigen Recognition - p. 62 12. Section 3: Physiology - p. 65 13. 10. Antigen Processing and Presentation - p. 66 14. 11. Lymphocyte Activation - p. 72 15. 12. Hematopoiesis - p. 80 16. 13. Organs and Tissues of the Immune System - p. 86 17. 14. B-Cell Development - p. 96 18. 15. T-Cell Development - p. 103 19. 16. T-Cell Interactions and T-Cell Help - p. 113 20. 17. Immunologic Memory and Homeostasis - p. 124 21. 18. Regulation of the Immune System - p. 130 22. 19. Brief Review of Immune Physiology - p. 136 23. Section 4: Innate Immunity - p. 140 24. 20. Constitutive Defenses Including Complement - p. 141 25. 21. Phagocytes - p. 152 26. 22. Killing in the Immune System - p. 164 27. 23. Inflammation - p. 174 28. 24. Cytokines in the Immune System - p. 184 29. Section 5: Immune System in Health and Disease - p. 192 30. 25. Infections and Vaccines - p. 193 31. 26. Hypersensitivity Reactions - p. 202 32. 27. Immediate Hypersensitivity (Type I): Allergy - p. 208 33. 28. How Autoimmune Disease Develops - p. 219 34. 29. Antibody-Mediated Hypersensitivity (Type II) - p. 233 35. 30. Immune Complex Disease (Type III Hypersensitivity) - p. 240 36. 31. Delayed Hypersensitivity (Type IV) and Review of Hypersensitivity Reactions - p. 247 37. 32. Primary Immunodeficiency - p. 255 38. 33. Secondary Immunodeficiency - p. 265 39. 34. Transplantation - p. 274 40. 35. Tumor Immunology - p. 284 41. 36. Biopharmaceuticals - p. 294 42. Glossary - p. 303 43. Index - p. 307 44. Confidence is ClinicalKey - p. 314