Immunomodulatory Biomaterials and Nano-immunotherapies reviews the general cellular and biochemical barriers of the tumor microenvironment and other immune diseases, the ways they are addressed by modern immunotherapies, and the specific barriers facing particular immunotherapeutic approaches. The latest research on immunomodulatory biomaterials is examined, providing a perspective on their future opportunities in modulating disease treatment strategies. Translational considerations and lessons learned from the various components of nanotechnology-enabled immunotherapies, including conventional immunotherapies, nucleic acids, nanotechnology, and biotechnology-based therapeutics are assessed. Finally, a framework for the development of the next generation of nanotechnology-enabled immunotherapies is detailed, providing guidance and suggestions for those interested in the development of novel immunomodulatory nanobiomaterials. Immunomodulatory Biomaterials and Nano-immunotherapies is a key reference for researchers and developers working in biomaterials, nanotechnology, immunology, biomedical engineering and pharmaceutical sciences.
1. Cover image - p. c 2. Title page - p. iii 3. Copyright - p. iv 4. Dedication - p. v 5. Table of Contents - p. vii 6. Contributors - p. xiii 7. Chapter 1 What is immunoengineering? - p. 1 8. Chapter 2 Immunoengineering - drug delivery - p. 21 9. Chapter 3 Immunoengineering-gene delivery - p. 39 10. Chapter 4 Nanoimmunotherapy and nanomedicine - p. 59 11. Chapter 5 Cancer immunotherapy - p. 117 12. Chapter 6 Nanotechnology-based CAR strategies for tumor immunotherapy - p. 135 13. Chapter 7 Nano-immunoimaging - p. 161 14. Chapter 8 Biomaterials-based strategies for cancer vaccines - p. 197 15. Chapter 9 Biomaterials for immuno-engineering - p. 259 16. Chapter 10 Chemistry of immunoengineering biomaterials - p. 313 17. Chapter 11 Cytokine engineering for targeted immunotherapy - p. 335 18. Chapter 12 Commercialization of nanoimmunoengineering - p. 371 19. Chapter 13 Impacts of material surface properties on immunomodulation of bone regeneration - p. 391 20. Index - p. 431
Immunomodulatory Biomaterials and Nano-immunotherapies reviews the general cellular and biochemical barriers of the tumor microenvironment and other immune diseases, the ways they are addressed by modern immunotherapies, and the specific barriers facing particular immunotherapeutic approaches. The latest research on immunomodulatory biomaterials is examined, providing a perspective on their future opportunities in modulating disease treatment strategies. Translational considerations and lessons learned from the various components of nanotechnology-enabled immunotherapies, including conventional immunotherapies, nucleic acids, nanotechnology, and biotechnology-based therapeutics are assessed. Finally, a framework for the development of the next generation of nanotechnology-enabled immunotherapies is detailed, providing guidance and suggestions for those interested in the development of novel immunomodulatory nanobiomaterials. Immunomodulatory Biomaterials and Nano-immunotherapies is a key reference for researchers and developers working in biomaterials, nanotechnology, immunology, biomedical engineering and pharmaceutical sciences.
1. Cover image - p. c 2. Title page - p. iii 3. Copyright - p. iv 4. Dedication - p. v 5. Table of Contents - p. vii 6. Contributors - p. xiii 7. Chapter 1 What is immunoengineering? - p. 1 8. Chapter 2 Immunoengineering - drug delivery - p. 21 9. Chapter 3 Immunoengineering-gene delivery - p. 39 10. Chapter 4 Nanoimmunotherapy and nanomedicine - p. 59 11. Chapter 5 Cancer immunotherapy - p. 117 12. Chapter 6 Nanotechnology-based CAR strategies for tumor immunotherapy - p. 135 13. Chapter 7 Nano-immunoimaging - p. 161 14. Chapter 8 Biomaterials-based strategies for cancer vaccines - p. 197 15. Chapter 9 Biomaterials for immuno-engineering - p. 259 16. Chapter 10 Chemistry of immunoengineering biomaterials - p. 313 17. Chapter 11 Cytokine engineering for targeted immunotherapy - p. 335 18. Chapter 12 Commercialization of nanoimmunoengineering - p. 371 19. Chapter 13 Impacts of material surface properties on immunomodulation of bone regeneration - p. 391 20. Index - p. 431
