Infections of the liver and biliary system are not uncommon, while most of the infections are viral in nature. Globally, viral hepatitis is a major public health problem and parallels infections such as HIV and tuberculosis and is associated with significant morbidity and mortality. Rapid advances have been made with HCV therapy at a time when the community focus has shifted to global elimination. This issue highlights some of the areas of considerable advances and challenges in viral hepatitis B and C. In addition, Hepatitis E is resurfacing as an infection of significance, particularly in the Western World where there is a prevalence of chronic infections. Gastroenterologists and hepatologists often think of viral hepatitis as the sole cause of hepatic infections, but there are other infections caused to bacteria, fungi and parasites; this issue highlights these infections as well. Articles are devoted to the following topics: Global epidemiology of viral hepatitis; Update on diagnostics in viral hapatitis; Heptatitis B: Immunization and impact on natural history and cancer incidence; Heptatitis B: Current status of therapy and future therapies; Hepatitis Delta: Prevalence, natural history, and treatment options; Hepatitis C: How good is real-life data and do generics work: Hepatitis C: Does successful treatment alter the natural history and quality of life; Hepatitis E: Epidemiology,clinical course, prevention, and treatment; CMV and EBV infections of the liver; Extrahepatic manifestations of viral hepatitis; Pyogenic and amebic infections of the liver; and Fungal and parasitic infections of the liver.
1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. Gastroenterology Clinics of North America - p. xi 7. Global Epidemiology of Viral Hepatitis - p. 179 8. Hepatitis A: Epidemiology, Natural History, Unusual Clinical Manifestations, and Prevention - p. 191 9. Hepatitis B: Immunization and Impact on Natural History and Cancer Incidence - p. 201 10. Hepatitis B: Current Status of Therapy and Future Therapies - p. 215 11. Hepatitis Delta: Prevalence, Natural History, and Treatment Options - p. 239 12. Progress Toward Hepatitis C Virus Elimination: Therapy and Implementation - p. 253 13. Hepatitis C: How Good Are Real-Life Data and Do Generics Work - p. 279 14. Hepatitis C: Does Successful Treatment Alter the Natural History and Quality of Life? - p. 301 15. Hepatitis E: Epidemiology, Clinical Course, Prevention, and Treatment - p. 315 16. Epstein-Barr Virus and Cytomegalovirus Infections of the Liver - p. 331 17. Extrahepatic Manifestations of Chronic Viral C Hepatitis - p. 347 18. Pyogenic and Amebic Infections of the Liver - p. 361 19. Fungal and Parasitic Infections of the Liver - p. 379
Infections of the liver and biliary system are not uncommon, while most of the infections are viral in nature. Globally, viral hepatitis is a major public health problem and parallels infections such as HIV and tuberculosis and is associated with significant morbidity and mortality. Rapid advances have been made with HCV therapy at a time when the community focus has shifted to global elimination. This issue highlights some of the areas of considerable advances and challenges in viral hepatitis B and C. In addition, Hepatitis E is resurfacing as an infection of significance, particularly in the Western World where there is a prevalence of chronic infections. Gastroenterologists and hepatologists often think of viral hepatitis as the sole cause of hepatic infections, but there are other infections caused to bacteria, fungi and parasites; this issue highlights these infections as well. Articles are devoted to the following topics: Global epidemiology of viral hepatitis; Update on diagnostics in viral hapatitis; Heptatitis B: Immunization and impact on natural history and cancer incidence; Heptatitis B: Current status of therapy and future therapies; Hepatitis Delta: Prevalence, natural history, and treatment options; Hepatitis C: How good is real-life data and do generics work: Hepatitis C: Does successful treatment alter the natural history and quality of life; Hepatitis E: Epidemiology,clinical course, prevention, and treatment; CMV and EBV infections of the liver; Extrahepatic manifestations of viral hepatitis; Pyogenic and amebic infections of the liver; and Fungal and parasitic infections of the liver.
1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. Gastroenterology Clinics of North America - p. xi 7. Global Epidemiology of Viral Hepatitis - p. 179 8. Hepatitis A: Epidemiology, Natural History, Unusual Clinical Manifestations, and Prevention - p. 191 9. Hepatitis B: Immunization and Impact on Natural History and Cancer Incidence - p. 201 10. Hepatitis B: Current Status of Therapy and Future Therapies - p. 215 11. Hepatitis Delta: Prevalence, Natural History, and Treatment Options - p. 239 12. Progress Toward Hepatitis C Virus Elimination: Therapy and Implementation - p. 253 13. Hepatitis C: How Good Are Real-Life Data and Do Generics Work - p. 279 14. Hepatitis C: Does Successful Treatment Alter the Natural History and Quality of Life? - p. 301 15. Hepatitis E: Epidemiology, Clinical Course, Prevention, and Treatment - p. 315 16. Epstein-Barr Virus and Cytomegalovirus Infections of the Liver - p. 331 17. Extrahepatic Manifestations of Chronic Viral C Hepatitis - p. 347 18. Pyogenic and Amebic Infections of the Liver - p. 361 19. Fungal and Parasitic Infections of the Liver - p. 379