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Descripción

Intracellular Signalling Proteins, Volume 116, presents an overview of the current developments in mechanisms of intracellular signaling and involvement of these mechanisms in the development of a number of disorders and diseases. Opportunities for targeting the intracellular signaling cascades for benefiting patients are also discussed, along with chapters that focus on Voices from the Dead: The Complex Language of Dead Cells, Nucleobindins and Encoded Peptides: From Cell Signalling to Physiology, Estrogen Receptor Signaling Mechanisms, Intracellular Signaling of the AMP-Activating Protein Kinase, the Relationship between Mitofusin 2 and Cancer, Molecular Signaling in Bone Cells: Regulation Cell Differentiation and Survival, and more.

  • Describes advances in the discovery and application of therapeutics that target intracellular signaling mechanisms
  • Targeted to a very wide audience of specialists, researchers and students
  • Contains timely chapters written by well-renowned authorities in their field
  • Includes a number of high quality illustrations, figures and tables

1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. Contributors - p. xi 6. Chapter One: Voices from the dead: The complex vocabulary and intricate grammar of dead cells - p. xi 7. Chapter Two: Nucleobindins and encoded peptides: From cell signaling to physiology - p. 90 8. Chapter Three: Estrogen receptor signaling mechanisms - p. 133 9. Chapter Four: Intracellular signaling of the AMP-activated protein kinase - p. 170 10. Chapter Five: Relationship between mitofusin 2 and cancer - p. 207 11. Chapter Six: Molecular signaling in bone cells: Regulation of cell differentiation and survival - p. 236 12. Chapter Seven: Activating mutations of the gp130/JAK/STAT pathway in human diseases - p. 281 13. Chapter Eight: Aquaporin water channels: New perspectives on the potential role in inflammation - p. 309 14. Chapter Nine: Intracellular protein complexes involved in synapse assembly in presynaptic neurons - p. 345 15. Chapter Ten: Dopamine signaling in the striatum - p. 373 16. Chapter Eleven: Recent advances in computational studies of GPCR-G protein interactions - p. 396 17. Chapter Twelve: From traveler to homebody: Which signaling mechanisms sponge larvae use to become adult sponges? - p. 419

Descripcion
Descripción

Intracellular Signalling Proteins, Volume 116, presents an overview of the current developments in mechanisms of intracellular signaling and involvement of these mechanisms in the development of a number of disorders and diseases. Opportunities for targeting the intracellular signaling cascades for benefiting patients are also discussed, along with chapters that focus on Voices from the Dead: The Complex Language of Dead Cells, Nucleobindins and Encoded Peptides: From Cell Signalling to Physiology, Estrogen Receptor Signaling Mechanisms, Intracellular Signaling of the AMP-Activating Protein Kinase, the Relationship between Mitofusin 2 and Cancer, Molecular Signaling in Bone Cells: Regulation Cell Differentiation and Survival, and more.

  • Describes advances in the discovery and application of therapeutics that target intracellular signaling mechanisms
  • Targeted to a very wide audience of specialists, researchers and students
  • Contains timely chapters written by well-renowned authorities in their field
  • Includes a number of high quality illustrations, figures and tables

1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. Contributors - p. xi 6. Chapter One: Voices from the dead: The complex vocabulary and intricate grammar of dead cells - p. xi 7. Chapter Two: Nucleobindins and encoded peptides: From cell signaling to physiology - p. 90 8. Chapter Three: Estrogen receptor signaling mechanisms - p. 133 9. Chapter Four: Intracellular signaling of the AMP-activated protein kinase - p. 170 10. Chapter Five: Relationship between mitofusin 2 and cancer - p. 207 11. Chapter Six: Molecular signaling in bone cells: Regulation of cell differentiation and survival - p. 236 12. Chapter Seven: Activating mutations of the gp130/JAK/STAT pathway in human diseases - p. 281 13. Chapter Eight: Aquaporin water channels: New perspectives on the potential role in inflammation - p. 309 14. Chapter Nine: Intracellular protein complexes involved in synapse assembly in presynaptic neurons - p. 345 15. Chapter Ten: Dopamine signaling in the striatum - p. 373 16. Chapter Eleven: Recent advances in computational studies of GPCR-G protein interactions - p. 396 17. Chapter Twelve: From traveler to homebody: Which signaling mechanisms sponge larvae use to become adult sponges? - p. 419

Indice
Autores
Muestra
Ficha Técnica