Imaging mass spectrometry (MS) techniques are often utilized without an understanding of their underlying principles, making it difficult for scientists to determine when and how they can exploit MS to visualize their biomolecules of interest. Introduction to Spatial Mapping of Biomolecules by Imaging Mass Spectrometry is an essential reference to help scientists determine the status and strategies of biomolecule analysis, describing its many applications for diverse classes of biomolecules.
The book builds a foundation of imaging MS knowledge by introducing ionization sources, sample preparation, visualization guidelines, molecule identification, quantification, data analysis, etc. The second section contains chapters focused on case studies on analyzing a biomolecule class of molecules. Case studies include an introduction/background, and a summary of successful imaging MS studies with illustrative figures and future directions.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iii 6. Contents - p. iii 7. Preface - p. iii 8. Chapter 1. Fundamentals of imaging mass spectrometry - p. iii 9. Chapter 2. Ionization sources for imaging mass spectrometry - p. iii 10. Chapter 3. Sample preparation for imaging mass spectrometry - p. iii 11. Chapter 4. Tissue sectioning for imaging mass spectrometry - p. iii 12. Chapter 5. Matrix for matrix-assisted laser desorption/ionization (MALDI) - p. iii 13. Chapter 6. Molecule identification approaches in imaging mass spectrometry - p. iii 14. Chapter 7. Strategies for quantitative imaging mass spectrometry - p. iii 15. Chapter 8. Spatial resolution of imaging mass spectrometry - p. iii 16. Chapter 9. Visualization in imaging mass spectrometry - p. iii 17. Chapter 10. Data analysis and computation for imaging mass spectrometry - p. iii 18. Chapter 11. Multimodal imaging mass spectrometry - p. iii 19. Chapter 12. Validation and standardization of imaging mass spectrometry - p. iii 20. Chapter 13. Toward clinical imaging mass spectrometry - p. iii 21. Chapter 14. Imaging mass spectrometry: endogenous mammalian metabolites - p. iii 22. Chapter 15. Imaging mass spectrometry: Glycans - p. iii 23. Chapter 16. Imaging mass spectrometry: steroids mapping using on-tissue chemical derivatization - p. iii 24. Chapter 17. Imaging mass spectrometry: neurotransmitter distribution using reactive matrix and chemical derivatization - p. iii 25. Chapter 18. Imaging mass spectrometry: small drugs and metabolites in tissue - p. iii 26. Chapter 19. Imaging mass spectrometry: gangliosides in brain tissue - p. iii 27. Index - p. iii
Imaging mass spectrometry (MS) techniques are often utilized without an understanding of their underlying principles, making it difficult for scientists to determine when and how they can exploit MS to visualize their biomolecules of interest. Introduction to Spatial Mapping of Biomolecules by Imaging Mass Spectrometry is an essential reference to help scientists determine the status and strategies of biomolecule analysis, describing its many applications for diverse classes of biomolecules.
The book builds a foundation of imaging MS knowledge by introducing ionization sources, sample preparation, visualization guidelines, molecule identification, quantification, data analysis, etc. The second section contains chapters focused on case studies on analyzing a biomolecule class of molecules. Case studies include an introduction/background, and a summary of successful imaging MS studies with illustrative figures and future directions.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iii 6. Contents - p. iii 7. Preface - p. iii 8. Chapter 1. Fundamentals of imaging mass spectrometry - p. iii 9. Chapter 2. Ionization sources for imaging mass spectrometry - p. iii 10. Chapter 3. Sample preparation for imaging mass spectrometry - p. iii 11. Chapter 4. Tissue sectioning for imaging mass spectrometry - p. iii 12. Chapter 5. Matrix for matrix-assisted laser desorption/ionization (MALDI) - p. iii 13. Chapter 6. Molecule identification approaches in imaging mass spectrometry - p. iii 14. Chapter 7. Strategies for quantitative imaging mass spectrometry - p. iii 15. Chapter 8. Spatial resolution of imaging mass spectrometry - p. iii 16. Chapter 9. Visualization in imaging mass spectrometry - p. iii 17. Chapter 10. Data analysis and computation for imaging mass spectrometry - p. iii 18. Chapter 11. Multimodal imaging mass spectrometry - p. iii 19. Chapter 12. Validation and standardization of imaging mass spectrometry - p. iii 20. Chapter 13. Toward clinical imaging mass spectrometry - p. iii 21. Chapter 14. Imaging mass spectrometry: endogenous mammalian metabolites - p. iii 22. Chapter 15. Imaging mass spectrometry: Glycans - p. iii 23. Chapter 16. Imaging mass spectrometry: steroids mapping using on-tissue chemical derivatization - p. iii 24. Chapter 17. Imaging mass spectrometry: neurotransmitter distribution using reactive matrix and chemical derivatization - p. iii 25. Chapter 18. Imaging mass spectrometry: small drugs and metabolites in tissue - p. iii 26. Chapter 19. Imaging mass spectrometry: gangliosides in brain tissue - p. iii 27. Index - p. iii
