Pharmacology of Ketamine: Fundamentals, Applications, Delivery Systems and Clinical Aspects explores the multifaceted properties of ketamine for diverse applications, delving into dosing strategies, routes of administration, and their pharmacological implications. The book begins with an introduction that underscores the need to bridge research and practice. It then delves into the pharmacological intricacies of ketamine, dissecting mechanisms and dosing strategies and exploring the diverse routes of administration and their impact on ketamine's metabolites.
The book then explores the PK and PD characteristics of ketamine, followed by a deep dive into clinical applications emphasizing anesthesia, psychiatric therapy, and emerging treatments. The final part of the book covers addiction, toxicity, and future research perspectives. It will serve as a comprehensive reference tailored to the needs of both researchers and clinicians involved in the administration and study of ketamine.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. Contributors - p. xiii 7. Preface - p. xv 8. Chapter 1. Ketamine and its metabolites—Mechanism of action - p. 1 9. Chapter 2. Ketamine pharmacokinetics and pharmacodynamics - p. 11 10. Chapter 3. Ketamine effects on brain dynamics - p. 37 11. Chapter 4. Ketamine for depression and other psychiatric diseases - p. 57 12. Chapter 5. Understanding ketamine subjective effects - p. 83 13. Chapter 6. Ketamine for acute and chronic pain - p. 119 14. Chapter 7. Ketamine for neuropathic pain: Animal and human studies - p. 141 15. Chapter 8. Ketamine for addiction treatment - p. 177 16. Chapter 9. Cardiorespiratory effects of ketamine - p. 197 17. Chapter 10. Ketamine toxicity: Translating preclinical findings to adverse effects in humans - p. 207 18. Chapter 11. Recreational use of ketamine - p. 245 19. Chapter 12. Ketamine in the era of the opioid crisis - p. 279 20. Chapter 13. Future perspectives - p. 299 21. Index - p. 315
Pharmacology of Ketamine: Fundamentals, Applications, Delivery Systems and Clinical Aspects explores the multifaceted properties of ketamine for diverse applications, delving into dosing strategies, routes of administration, and their pharmacological implications. The book begins with an introduction that underscores the need to bridge research and practice. It then delves into the pharmacological intricacies of ketamine, dissecting mechanisms and dosing strategies and exploring the diverse routes of administration and their impact on ketamine's metabolites.
The book then explores the PK and PD characteristics of ketamine, followed by a deep dive into clinical applications emphasizing anesthesia, psychiatric therapy, and emerging treatments. The final part of the book covers addiction, toxicity, and future research perspectives. It will serve as a comprehensive reference tailored to the needs of both researchers and clinicians involved in the administration and study of ketamine.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. Contributors - p. xiii 7. Preface - p. xv 8. Chapter 1. Ketamine and its metabolites—Mechanism of action - p. 1 9. Chapter 2. Ketamine pharmacokinetics and pharmacodynamics - p. 11 10. Chapter 3. Ketamine effects on brain dynamics - p. 37 11. Chapter 4. Ketamine for depression and other psychiatric diseases - p. 57 12. Chapter 5. Understanding ketamine subjective effects - p. 83 13. Chapter 6. Ketamine for acute and chronic pain - p. 119 14. Chapter 7. Ketamine for neuropathic pain: Animal and human studies - p. 141 15. Chapter 8. Ketamine for addiction treatment - p. 177 16. Chapter 9. Cardiorespiratory effects of ketamine - p. 197 17. Chapter 10. Ketamine toxicity: Translating preclinical findings to adverse effects in humans - p. 207 18. Chapter 11. Recreational use of ketamine - p. 245 19. Chapter 12. Ketamine in the era of the opioid crisis - p. 279 20. Chapter 13. Future perspectives - p. 299 21. Index - p. 315
