**Selected for 2025 Doody’s Core Titles® in Psychiatry**
Offering today’s most authoritative, comprehensive coverage of sleep disorders, Kryger’s Principles and Practice of Sleep Medicine, 7th Edition, is a must-have resource for sleep medicine specialists, fellows, trainees, and technicians, as well as pulmonologists, neurologists, and other clinicians who see patients with sleep-related issues. It provides a solid understanding of underlying basic science as well as complete coverage of emerging advances in management and treatment for a widely diverse patient population. Evidence-based content, hundreds of full-color illustrations, and a wealth of additional resources online help you make well-informed clinical decisions and offer your patients the best possible care.
1. Chapter 6: Introduction/Defining Sleep - p. 52 2. Chapter 7: Neural Control of Sleep in Mammals - p. 54 3. Chapter 8: Rapid Eye Movement Sleep Control and Function - p. 68 4. Chapter 9: Deep-Brain Imaging of Brain Neurons and Glia during Sleep - p. 87 5. Chapter 10: Evolution of Mammalian Sleep - p. 93 6. Chapter 11: Sleep in Nonmammalian Vertebrates - p. 106 7. Section 3. Genetics and Genomic Basis of Sleep - p. 120.e5 8. Chapter 12: Introduction - p. 121 9. Chapter 13: Genetics and Genomics of Circadian Clocks - p. 123 10. Chapter 14: Genetics and Genomic Basis of Sleep in Simple Model Organisms - p. 133 11. Chapter 15: Genetic and Genomic Basis of Sleep in Rodents - p. 148 12. Chapter 16: Genetics and Genomic Basis of Sleep in Healthy Humans - p. 164 13. Chapter 17: Genetics and Genomic Basis of Sleep Disorders in Humans - p. 175 14. Section 4. Physiology in Sleep - p. 192.e8 15. Chapter 18: Introduction to Physiology in Sleep - p. 193 16. Chapter 19: What Neuroimaging Reveals about the Brain Areas Generating, Maintaining, and Regulating Sleep - p. 195 17. Chapter 20: Cardiovascular Physiology and Coupling with Respiration - p. 209 18. Chapter 21: Cardiovascular Physiology - p. 221 19. Chapter 22: Respiratory Physiology - p. 233 20. Chapter 23: Respiratory Physiology - p. 245 21. Chapter 24: Physiology of Upper and Lower Airways - p. 252 22. Chapter 25: Respiratory Physiology - p. 260 23. Chapter 26: Sleep and Host Defense - p. 274 24. Chapter 27: Endocrine Physiology in Relation to Sleep and Sleep Disturbances - p. 284 25. Chapter 28: Thermoregulation in Sleep and Hibernation - p. 301 26. Chapter 29: Memory Processing in Relation to Sleep - p. 311 27. Chapter 30: Sensory and Motor Processing during Sleep and Wakefulness - p. 321 28. Chapter 31: Local and Use-Dependent Aspects of Sleep - p. 333 29. Chapter 32: Pathophysiology of Sleep-Wake Disturbances after Traumatic Brain Injury - p. 339 30. Section 5. Chronobiology - p. 348.e5 31. Chapter 33: Introduction - p. 349 32. Chapter 34: Master Circadian Clock and Master Circadian Rhythm - p. 351 33. Chapter 35: Anatomy of the Mammalian Circadian System - p. 354 34. Chapter 36: Physiology of the Mammalian Circadian System - p. 362 35. Chapter 37: Human Circadian Timing System and Sleep-Wake Regulation - p. 375 36. Chapter 38: Sleep Homeostasis and Models of Sleep Regulation - p. 390 37. Chapter 39: Circadian Rhythms in Sleepiness, Alertness, and Performance - p. 407 38. Chapter 40: Central and Peripheral Circadian Clocks - p. 415 39. Chapter 41: Circadian Dysregulation and Cardiometabolic and Immune Health - p. 423 40. Chapter 42: Circadian Dysregulation in Brain Aging and Neuropsychiatric Health - p. 433 41. Chapter 43: Circadian Disorders of the Sleep-Wake Cycle - p. 441 42. Section 6. Pharmacology - p. 450.e6 43. Chapter 44: Introduction - p. 451 44. Chapter 45: Adenosinergic Control of Sleep - p. 452 45. Chapter 46: Catecholamines - p. 460 46. Chapter 47: GABA - p. 472 47. Chapter 48: Histamine - p. 483 48. Chapter 49: Orexin/Hypocretin - p. 488 49. Chapter 50: Serotonin and Sleep - p. 497 50. Chapter 51: Melatonin - p. 506 51. Chapter 52: Opioid Actions on Sleep and Breathing - p. 510 52. Chapter 53: Clinical Pharmacology of Drugs that Affect Sleep and Wake - p. 519 53. Section 7. Psychobiology and Dreaming - p. 547.e9 54. Chapter 54: Introduction - p. 548 55. Chapter 55: Why We Dream - p. 551 56. Chapter 56: Dream Content - p. 557 57. Chapter 57: Neural Correlates of Dreaming - p. 564 58. Chapter 58: The Neurobiology of Dreaming - p. 569 59. Chapter 59: Lucid Dreaming - p. 579 60. Chapter 60: What Is the Function of Nightmares? - p. 586 61. Chapter 61: Dreams and Nightmares in Posttraumatic Stress Disorder - p. 594 62. Chapter 62: Incorporation of Waking Experiences into Dreams - p. 600 63. Chapter 63: Emotion, Motivation, and Reward in Relation to Dreaming - p. 606 64. Chapter 64: Dreaming during Pregnancy - p. 610 65. Practice of Sleep Medicine - p. 618.e4 66. Section 8. Impact, Presentation, and Diagnosis - p. 618.e4 67. Chapter 65: Approach to the Patient with Disordered Sleep - p. 622 68. Chapter 66: Cardinal Manifestations of Sleep Disorders - p. 625 69. Chapter 67: Physical Examination in Sleep Medicine - p. 636 70. Chapter 68: Clinical Tools and Tests in Sleep Medicine - p. 666 71. Chapter 69: Classification of Sleep Disorders - p. 678 72. Chapter 70: Epidemiology of Sleep Medicine - p. 689 73. Chapter 71: Sleep Medicine, Public Policy, and Public Health - p. 699 74. Section 9. Legal Aspects of Sleep Medicine - p. 707.e4 75. Chapter 72: Introduction - p. 708 76. Chapter 73: Sleep Forensics - p. 709 77. Chapter 74: Legal Obligations of Persons Who Have Sleep Disorders or Who Treat or Hire Them - p. 717 78. Chapter 75: Legal Aspects of Fatigue- and Safety-Sensitive Professions - p. 723 79. Chapter 76: Sleep Medicine Clinical Practice and Compliance—United States - p. 727 80. Chapter 77: Sleep Medicine Clinical Practice and Compliance—Europe - p. 734 81. Section 10. Occupational Sleep Medicine - p. 738 82. Chapter 78: Introduction - p. 739 83. Chapter 79: Performance Deficits During Sleep Loss and Their Operational Consequences - p. 742 84. Chapter 80: Sleep and Sleep Disorders in Operational Settings - p. 750 85. Chapter 81: Shift Work, Shift-Work Disorder, Jet Lag, and Jet Lag Disorder - p. 761 86. Chapter 82: Fatigue Countermeasures - p. 774 87. Chapter 83: Sleep, Sleepiness, and Performance Prediction Modeling - p. 780 88. Chapter 84: Fatigue Risk Management Systems - p. 788 89. Chapter 85: Safety Cases and Assessing Alternative Means of Regulatory Compliance in Fatigue Risk Management - p. 796 90. Chapter 86: Fatigue Proofing - p. 804 91. Chapter 87: Sleep Health in Athlete Populations - p. 809 92. Chapter 88: Assessment of the Occupational Sleep Medicine Field - p. 814 93. Section 11. Insomnia - p. 820.e3 94. Chapter 89: Advances in Insomnia Pathophysiology and Treatment - p. 821 95. Chapter 90: Insomnia - p. 825 96. Chapter 91: Etiology and Pathophysiology of Insomnia - p. 835 97. Chapter 92: Pediatric Insomnia and Its Developmental Trajectories - p. 850 98. Chapter 93: Insomnia Diagnosis, Assessment, and Evaluation - p. 858 99. Chapter 94: Insomnia with Short Sleep Duration and Multidimensional Sleep Health - p. 867 100. Chapter 95: Behavioral Treatment I - p. 883 101. Chapter 96: Behavioral Treatment II - p. 890 102. Chapter 97: Behavioral Treatment III - p. 896 103. Chapter 98: Pharmacologic Treatment I - p. 902 104. Chapter 99: Pharmacologic Treatment II - p. 911 105. Chapter 100: Pharmacologic Treatment III - p. 922 106. Section 12. Neurologic Disorders - p. 934.e4 107. Chapter 101: Introduction - p. 935 108. Chapter 102: Parkinsonism - p. 937 109. Chapter 103: Sleep-Wake Disturbances and Stroke - p. 949 110. Chapter 104: Sleep and Neuromuscular Diseases - p. 959 111. Chapter 105: Alzheimer Disease and Other Dementias - p. 968 112. Chapter 106: Epilepsy, Sleep, and Sleep Disorders - p. 977 113. Chapter 107: Sleep and Headache - p. 985 114. Chapter 108: Sleep Disorders after Traumatic Brain Injury - p. 995 115. 109: Autoimmune Disorders (Autoimmune Encephalitides and Multiple Sclerosis) - p. 1006 116. Section 13. Hypersomnias - p. 1017.e4 117. Chapter 110: Central Disorders of Hypersomnolence - p. 1018 118. Chapter 111: Narcolepsy - p. 1020 119. Chapter 112: Narcolepsy - p. 1038 120. Chapter 113: Idiopathic Hypersomnia - p. 1048 121. Chapter 114: Kleine-Levin Syndrome - p. 1057 122. Section 14. Parasomnias - p. 1065.e4 123. Chapter 115: Parasomnias and Sleep-Related Movement Disorders - p. 1066 124. Chapter 116: Disorders of Arousal - p. 1071 125. Chapter 117: Sleep-Related Eating Disorder - p. 1087 126. Chapter 118: Rapid Eye Movement Sleep Parasomnias - p. 1093 127. Chapter 119: Nightmares and Dream Disturbances - p. 1102 128. Chapter 120: Other Parasomnias - p. 1110 129. Chapter 121: Restless Legs Syndrome (Willis-Ekbom Disease) and Periodic Limb Movements during Sleep - p. 1119 130. Chapter 122: Sleep-Related Movement Disorders and Their Unique Motor Manifestations - p. 1132 131. Section 15. Sleep Breathing Disorders - p. 1139.e3 132. Chapter 123: Introduction - p. 1140 133. Chapter 124: Central Sleep Apnea - p. 1144 134. Chapter 125: Central Sleep Apnea - p. 1154 135. Chapter 126: Anatomy and Physiology of Upper Airway Obstruction - p. 1170 136. Chapter 127: Snoring and Pathologic Upper Airway Resistance Syndromes - p. 1184 137. Chapter 128: Obstructive Sleep Apnea - p. 1197 138. Chapter 129: Deep Phenotyping of Sleep Apnea - p. 1209 139. Chapter 130: Clinical and Physiologic Heterogeneity of Obstructive Sleep Apnea - p. 1238 140. Chapter 131: Obstructive Sleep Apnea - p. 1244 141. Chapter 132: Positive Airway Pressure Treatment for Obstructive Sleep Apnea - p. 1260 142. Chapter 133: Pharmacologic Treatments for Obstructive Sleep Apnea - p. 1284 143. Chapter 134: Alternative Strategies to Management of Sleep-Disordered Breathing - p. 1294 144. Chapter 135: Brain Health in Sleep Apnea - p. 1304 145. Chapter 136: Obstructive Sleep Apnea and Metabolic Disorders - p. 1318 146. Chapter 137: Overlap Syndromes of Sleep and Breathing Disorders - p. 1326 147. Chapter 138: Obesity-Hypoventilation Syndrome - p. 1337 148. Chapter 139: Obstructive Sleep Apnea, Obesity, and Bariatric Surgery - p. 1349 149. Chapter 140: Advanced Modes of Positive Pressure Therapy for Sleep-Disordered Breathing - p. 1363 150. Chapter 141: Sleep and Breathing at High Altitude - p. 1389 151. Chapter 142: Evolution of Sleep-Disordered Breathing across the Adult Years - p. 1401 152. Section 16. Cardiovascular Disorders - p. 1404.e5 153. Chapter 143: Introduction - p. 1405 154. Chapter 144: Sleep-Related Cardiac Risk - p. 1410 155. Chapter 145: Cardiac Arrhythmogenesis during Sleep - p. 1421 156. Chapter 146: Cardiovascular Effects of Sleep-Related Breathing Disorders - p. 1430 157. Chapter 147: Systemic and Pulmonary Hypertension in Obstructive Sleep Apnea - p. 1440 158. Chapter 148: Coronary Artery Disease and Obstructive Sleep Apnea - p. 1453 159. Chapter 149: Heart Failure - p. 1462 160. Chapter 150: Sleep-Disordered Breathing and Stroke - p. 1477 161. Chapter 151: Insomnia and Cardiovascular Disease - p. 1484 162. Section 17. Other Medical Disorders - p. 1489.e4 163. Chapter 152: Introduction - p. 1490 164. Chapter 153: Sleep and Cancer across the Life Span - p. 1492 165. Chapter 154: Fibromyalgia and Chronic Fatigue Syndromes - p. 1501 166. Chapter 155: Endocrine Disorders - p. 1507 167. Chapter 156: Pain and Sleep - p. 1519 168. Chapter 157: Sleep and Chronic Kidney Disease - p. 1533 169. Chapter 158: Sleep in the Critically Ill Patient - p. 1540 170. Chapter 159: Perioperative Sleep Medicine - p. 1552 171. Chapter 160: Sleep and Gastrointestinal Health - p. 1557 172. Section 18. Psychiatric Disorders - p. 1564.e7 173. Chapter 161: Introduction - p. 1565 174. Chapter 162: Emotion and Sleep - p. 1567 175. Chapter 163: Anxiety Disorders and Posttraumatic Stress Disorder - p. 1573 176. Chapter 164: Affective Disorders - p. 1584 177. Chapter 165: Schizophrenia and Sleep - p. 1591 178. Chapter 166: Substance Abuse - p. 1600 179. Section 19. Dentistry and Otorhinolaryngology - p. 1607.e5 180. Chapter 167: Dentistry and Otorhinolaryngology in Sleep Medicine - p. 1608 181. Chapter 168: Oronasopharyngeal Growth and Malformations with Orthodontic Management - p. 1610 182. Chapter 169: Sleep Bruxism - p. 1631 183. Chapter 170: Assessment of Sleep Bruxism - p. 1636 184. Chapter 171: Management of Sleep Bruxism - p. 1645 185. Chapter 172: Orofacial Pain/Temporomandibular Disorders in Relation to Sleep Bruxism and Breathing Disorders - p. 1651 186. Chapter 173: Oral Appliances for the Treatment of Sleep-Disordered Breathing - p. 1657 187. Chapter 174: Anesthesia in Upper Airway Surgery - p. 1671 188. Chapter 175: Upper Airway Surgery to Treat Obstructive Sleep-Disordered Breathing - p. 1677 189. Chapter 176: Pharmacotherapy and Behavioral, Complementary, and Alternative Medicine for Sleep Bruxism - p. 1692 190. Section 20. From Childhood to Adulthood - p. 1698.e5 191. Chapter 177: Overview - p. 1699 192. Chapter 178: Sleep-Related Breathing Disorders in Children - p. 1702 193. Chapter 179: Neuromuscular and Neurological Disorders - p. 1707 194. Chapter 180: Transitional Care for Adolescents with Narcolepsy and Other Central Disorders of Hypersomnolence - p. 1714 195. Chapter 181: Congenital Heart Disease - p. 1722 196. Chapter 182: Sleep in Intersex and Transgender Individuals - p. 1727 197. Section 21. Sleep in Women - p. 1730.e3 198. Chapter 183: Introduction - p. 1731 199. Chapter 184: Sex Effects and Differences in Circadian Rhythms and Sleep - p. 1734 200. Chapter 185: The Menstrual Cycle, Sleep, and Circadian Rhythms - p. 1742 201. Chapter 186: Sleep and Sleep Disorders Associated with Pregnancy - p. 1751 202. Chapter 187: Sleep-Disordered Breathing in Pregnancy - p. 1764 203. Chapter 188: Postpartum Period and Early Parenthood - p. 1773 204. Chapter 189: Sleep and Menopause - p. 1781 205. Section 22. Sleep Medicine in the Elderly - p. 1792.e6 206. Chapter 190: Introduction - p. 1793 207. Chapter 191: Psychiatric and Medical Comorbidities and Effects of Medications in Older Adults - p. 1795 208. Chapter 192: Obstructive Sleep Apnea in Older Adults - p. 1807 209. Chapter 193: Insomnia in Older Adults - p. 1814 210. Chapter 194: Circadian Rhythms in Older Adults - p. 1821 211. Chapter 195: Sleep in Long-Term Care Settings - p. 1825 212. Section 23. Methodology - p. 1834.e6 213. Chapter 196: Section Introduction - p. 1835 214. Chapter 197: Sleep Stage Scoring - p. 1839 215. Chapter 198: Central Nervous System Arousals and the Cyclic Alternating Pattern - p. 1848 216. Chapter 199: Neurologic Monitoring Techniques - p. 1857 217. Chapter 200: Monitoring Techniques for Evaluating Suspected Sleep-Related Breathing and Cardiovascular Disorders - p. 1867 218. Chapter 201: Sleep Telemedicine and Remote PAP Adherence Monitoring - p. 1882 219. Chapter 202: Cardiopulmonary Coupling - p. 1891 220. Chapter 203: Pulse Wave Analysis - p. 1902 221. Chapter 204: Recording and Scoring Sleep-Related Movements - p. 1911 222. Chapter 205: Home Sleep Testing for Sleep-Related Breathing Disorders - p. 1925 223. Chapter 206: Consumer Sleep Tracking - p. 1930 224. Chapter 207: Evaluating Sleepiness and Fatigue - p. 1941 225. Chapter 208: The Assessment of Insomnia - p. 1951 226. Chapter 209: Surveys, Sampling, and Polling Methods for Sleep and Public Health - p. 1966 227. Chapter 210: Techniques for Clinical Assessment of Circadian Rhythm Disorders - p. 1974 228. Chapter 211: Actigraphy Methods and Technical Issues - p. 1984 229. Chapter 212: Imaging - p. 1992 230. Section 24. Late Breaking - p. 1998.e3 231. Chapter 213: COVID-19 and Sleep - p. 1999 232. Index - p. I-1
**Selected for 2025 Doody’s Core Titles® in Psychiatry**
Offering today’s most authoritative, comprehensive coverage of sleep disorders, Kryger’s Principles and Practice of Sleep Medicine, 7th Edition, is a must-have resource for sleep medicine specialists, fellows, trainees, and technicians, as well as pulmonologists, neurologists, and other clinicians who see patients with sleep-related issues. It provides a solid understanding of underlying basic science as well as complete coverage of emerging advances in management and treatment for a widely diverse patient population. Evidence-based content, hundreds of full-color illustrations, and a wealth of additional resources online help you make well-informed clinical decisions and offer your patients the best possible care.
1. Chapter 6: Introduction/Defining Sleep - p. 52 2. Chapter 7: Neural Control of Sleep in Mammals - p. 54 3. Chapter 8: Rapid Eye Movement Sleep Control and Function - p. 68 4. Chapter 9: Deep-Brain Imaging of Brain Neurons and Glia during Sleep - p. 87 5. Chapter 10: Evolution of Mammalian Sleep - p. 93 6. Chapter 11: Sleep in Nonmammalian Vertebrates - p. 106 7. Section 3. Genetics and Genomic Basis of Sleep - p. 120.e5 8. Chapter 12: Introduction - p. 121 9. Chapter 13: Genetics and Genomics of Circadian Clocks - p. 123 10. Chapter 14: Genetics and Genomic Basis of Sleep in Simple Model Organisms - p. 133 11. Chapter 15: Genetic and Genomic Basis of Sleep in Rodents - p. 148 12. Chapter 16: Genetics and Genomic Basis of Sleep in Healthy Humans - p. 164 13. Chapter 17: Genetics and Genomic Basis of Sleep Disorders in Humans - p. 175 14. Section 4. Physiology in Sleep - p. 192.e8 15. Chapter 18: Introduction to Physiology in Sleep - p. 193 16. Chapter 19: What Neuroimaging Reveals about the Brain Areas Generating, Maintaining, and Regulating Sleep - p. 195 17. Chapter 20: Cardiovascular Physiology and Coupling with Respiration - p. 209 18. Chapter 21: Cardiovascular Physiology - p. 221 19. Chapter 22: Respiratory Physiology - p. 233 20. Chapter 23: Respiratory Physiology - p. 245 21. Chapter 24: Physiology of Upper and Lower Airways - p. 252 22. Chapter 25: Respiratory Physiology - p. 260 23. Chapter 26: Sleep and Host Defense - p. 274 24. Chapter 27: Endocrine Physiology in Relation to Sleep and Sleep Disturbances - p. 284 25. Chapter 28: Thermoregulation in Sleep and Hibernation - p. 301 26. Chapter 29: Memory Processing in Relation to Sleep - p. 311 27. Chapter 30: Sensory and Motor Processing during Sleep and Wakefulness - p. 321 28. Chapter 31: Local and Use-Dependent Aspects of Sleep - p. 333 29. Chapter 32: Pathophysiology of Sleep-Wake Disturbances after Traumatic Brain Injury - p. 339 30. Section 5. Chronobiology - p. 348.e5 31. Chapter 33: Introduction - p. 349 32. Chapter 34: Master Circadian Clock and Master Circadian Rhythm - p. 351 33. Chapter 35: Anatomy of the Mammalian Circadian System - p. 354 34. Chapter 36: Physiology of the Mammalian Circadian System - p. 362 35. Chapter 37: Human Circadian Timing System and Sleep-Wake Regulation - p. 375 36. Chapter 38: Sleep Homeostasis and Models of Sleep Regulation - p. 390 37. Chapter 39: Circadian Rhythms in Sleepiness, Alertness, and Performance - p. 407 38. Chapter 40: Central and Peripheral Circadian Clocks - p. 415 39. Chapter 41: Circadian Dysregulation and Cardiometabolic and Immune Health - p. 423 40. Chapter 42: Circadian Dysregulation in Brain Aging and Neuropsychiatric Health - p. 433 41. Chapter 43: Circadian Disorders of the Sleep-Wake Cycle - p. 441 42. Section 6. Pharmacology - p. 450.e6 43. Chapter 44: Introduction - p. 451 44. Chapter 45: Adenosinergic Control of Sleep - p. 452 45. Chapter 46: Catecholamines - p. 460 46. Chapter 47: GABA - p. 472 47. Chapter 48: Histamine - p. 483 48. Chapter 49: Orexin/Hypocretin - p. 488 49. Chapter 50: Serotonin and Sleep - p. 497 50. Chapter 51: Melatonin - p. 506 51. Chapter 52: Opioid Actions on Sleep and Breathing - p. 510 52. Chapter 53: Clinical Pharmacology of Drugs that Affect Sleep and Wake - p. 519 53. Section 7. Psychobiology and Dreaming - p. 547.e9 54. Chapter 54: Introduction - p. 548 55. Chapter 55: Why We Dream - p. 551 56. Chapter 56: Dream Content - p. 557 57. Chapter 57: Neural Correlates of Dreaming - p. 564 58. Chapter 58: The Neurobiology of Dreaming - p. 569 59. Chapter 59: Lucid Dreaming - p. 579 60. Chapter 60: What Is the Function of Nightmares? - p. 586 61. Chapter 61: Dreams and Nightmares in Posttraumatic Stress Disorder - p. 594 62. Chapter 62: Incorporation of Waking Experiences into Dreams - p. 600 63. Chapter 63: Emotion, Motivation, and Reward in Relation to Dreaming - p. 606 64. Chapter 64: Dreaming during Pregnancy - p. 610 65. Practice of Sleep Medicine - p. 618.e4 66. Section 8. Impact, Presentation, and Diagnosis - p. 618.e4 67. Chapter 65: Approach to the Patient with Disordered Sleep - p. 622 68. Chapter 66: Cardinal Manifestations of Sleep Disorders - p. 625 69. Chapter 67: Physical Examination in Sleep Medicine - p. 636 70. Chapter 68: Clinical Tools and Tests in Sleep Medicine - p. 666 71. Chapter 69: Classification of Sleep Disorders - p. 678 72. Chapter 70: Epidemiology of Sleep Medicine - p. 689 73. Chapter 71: Sleep Medicine, Public Policy, and Public Health - p. 699 74. Section 9. Legal Aspects of Sleep Medicine - p. 707.e4 75. Chapter 72: Introduction - p. 708 76. Chapter 73: Sleep Forensics - p. 709 77. Chapter 74: Legal Obligations of Persons Who Have Sleep Disorders or Who Treat or Hire Them - p. 717 78. Chapter 75: Legal Aspects of Fatigue- and Safety-Sensitive Professions - p. 723 79. Chapter 76: Sleep Medicine Clinical Practice and Compliance—United States - p. 727 80. Chapter 77: Sleep Medicine Clinical Practice and Compliance—Europe - p. 734 81. Section 10. Occupational Sleep Medicine - p. 738 82. Chapter 78: Introduction - p. 739 83. Chapter 79: Performance Deficits During Sleep Loss and Their Operational Consequences - p. 742 84. Chapter 80: Sleep and Sleep Disorders in Operational Settings - p. 750 85. Chapter 81: Shift Work, Shift-Work Disorder, Jet Lag, and Jet Lag Disorder - p. 761 86. Chapter 82: Fatigue Countermeasures - p. 774 87. Chapter 83: Sleep, Sleepiness, and Performance Prediction Modeling - p. 780 88. Chapter 84: Fatigue Risk Management Systems - p. 788 89. Chapter 85: Safety Cases and Assessing Alternative Means of Regulatory Compliance in Fatigue Risk Management - p. 796 90. Chapter 86: Fatigue Proofing - p. 804 91. Chapter 87: Sleep Health in Athlete Populations - p. 809 92. Chapter 88: Assessment of the Occupational Sleep Medicine Field - p. 814 93. Section 11. Insomnia - p. 820.e3 94. Chapter 89: Advances in Insomnia Pathophysiology and Treatment - p. 821 95. Chapter 90: Insomnia - p. 825 96. Chapter 91: Etiology and Pathophysiology of Insomnia - p. 835 97. Chapter 92: Pediatric Insomnia and Its Developmental Trajectories - p. 850 98. Chapter 93: Insomnia Diagnosis, Assessment, and Evaluation - p. 858 99. Chapter 94: Insomnia with Short Sleep Duration and Multidimensional Sleep Health - p. 867 100. Chapter 95: Behavioral Treatment I - p. 883 101. Chapter 96: Behavioral Treatment II - p. 890 102. Chapter 97: Behavioral Treatment III - p. 896 103. Chapter 98: Pharmacologic Treatment I - p. 902 104. Chapter 99: Pharmacologic Treatment II - p. 911 105. Chapter 100: Pharmacologic Treatment III - p. 922 106. Section 12. Neurologic Disorders - p. 934.e4 107. Chapter 101: Introduction - p. 935 108. Chapter 102: Parkinsonism - p. 937 109. Chapter 103: Sleep-Wake Disturbances and Stroke - p. 949 110. Chapter 104: Sleep and Neuromuscular Diseases - p. 959 111. Chapter 105: Alzheimer Disease and Other Dementias - p. 968 112. Chapter 106: Epilepsy, Sleep, and Sleep Disorders - p. 977 113. Chapter 107: Sleep and Headache - p. 985 114. Chapter 108: Sleep Disorders after Traumatic Brain Injury - p. 995 115. 109: Autoimmune Disorders (Autoimmune Encephalitides and Multiple Sclerosis) - p. 1006 116. Section 13. Hypersomnias - p. 1017.e4 117. Chapter 110: Central Disorders of Hypersomnolence - p. 1018 118. Chapter 111: Narcolepsy - p. 1020 119. Chapter 112: Narcolepsy - p. 1038 120. Chapter 113: Idiopathic Hypersomnia - p. 1048 121. Chapter 114: Kleine-Levin Syndrome - p. 1057 122. Section 14. Parasomnias - p. 1065.e4 123. Chapter 115: Parasomnias and Sleep-Related Movement Disorders - p. 1066 124. Chapter 116: Disorders of Arousal - p. 1071 125. Chapter 117: Sleep-Related Eating Disorder - p. 1087 126. Chapter 118: Rapid Eye Movement Sleep Parasomnias - p. 1093 127. Chapter 119: Nightmares and Dream Disturbances - p. 1102 128. Chapter 120: Other Parasomnias - p. 1110 129. Chapter 121: Restless Legs Syndrome (Willis-Ekbom Disease) and Periodic Limb Movements during Sleep - p. 1119 130. Chapter 122: Sleep-Related Movement Disorders and Their Unique Motor Manifestations - p. 1132 131. Section 15. Sleep Breathing Disorders - p. 1139.e3 132. Chapter 123: Introduction - p. 1140 133. Chapter 124: Central Sleep Apnea - p. 1144 134. Chapter 125: Central Sleep Apnea - p. 1154 135. Chapter 126: Anatomy and Physiology of Upper Airway Obstruction - p. 1170 136. Chapter 127: Snoring and Pathologic Upper Airway Resistance Syndromes - p. 1184 137. Chapter 128: Obstructive Sleep Apnea - p. 1197 138. Chapter 129: Deep Phenotyping of Sleep Apnea - p. 1209 139. Chapter 130: Clinical and Physiologic Heterogeneity of Obstructive Sleep Apnea - p. 1238 140. Chapter 131: Obstructive Sleep Apnea - p. 1244 141. Chapter 132: Positive Airway Pressure Treatment for Obstructive Sleep Apnea - p. 1260 142. Chapter 133: Pharmacologic Treatments for Obstructive Sleep Apnea - p. 1284 143. Chapter 134: Alternative Strategies to Management of Sleep-Disordered Breathing - p. 1294 144. Chapter 135: Brain Health in Sleep Apnea - p. 1304 145. Chapter 136: Obstructive Sleep Apnea and Metabolic Disorders - p. 1318 146. Chapter 137: Overlap Syndromes of Sleep and Breathing Disorders - p. 1326 147. Chapter 138: Obesity-Hypoventilation Syndrome - p. 1337 148. Chapter 139: Obstructive Sleep Apnea, Obesity, and Bariatric Surgery - p. 1349 149. Chapter 140: Advanced Modes of Positive Pressure Therapy for Sleep-Disordered Breathing - p. 1363 150. Chapter 141: Sleep and Breathing at High Altitude - p. 1389 151. Chapter 142: Evolution of Sleep-Disordered Breathing across the Adult Years - p. 1401 152. Section 16. Cardiovascular Disorders - p. 1404.e5 153. Chapter 143: Introduction - p. 1405 154. Chapter 144: Sleep-Related Cardiac Risk - p. 1410 155. Chapter 145: Cardiac Arrhythmogenesis during Sleep - p. 1421 156. Chapter 146: Cardiovascular Effects of Sleep-Related Breathing Disorders - p. 1430 157. Chapter 147: Systemic and Pulmonary Hypertension in Obstructive Sleep Apnea - p. 1440 158. Chapter 148: Coronary Artery Disease and Obstructive Sleep Apnea - p. 1453 159. Chapter 149: Heart Failure - p. 1462 160. Chapter 150: Sleep-Disordered Breathing and Stroke - p. 1477 161. Chapter 151: Insomnia and Cardiovascular Disease - p. 1484 162. Section 17. Other Medical Disorders - p. 1489.e4 163. Chapter 152: Introduction - p. 1490 164. Chapter 153: Sleep and Cancer across the Life Span - p. 1492 165. Chapter 154: Fibromyalgia and Chronic Fatigue Syndromes - p. 1501 166. Chapter 155: Endocrine Disorders - p. 1507 167. Chapter 156: Pain and Sleep - p. 1519 168. Chapter 157: Sleep and Chronic Kidney Disease - p. 1533 169. Chapter 158: Sleep in the Critically Ill Patient - p. 1540 170. Chapter 159: Perioperative Sleep Medicine - p. 1552 171. Chapter 160: Sleep and Gastrointestinal Health - p. 1557 172. Section 18. Psychiatric Disorders - p. 1564.e7 173. Chapter 161: Introduction - p. 1565 174. Chapter 162: Emotion and Sleep - p. 1567 175. Chapter 163: Anxiety Disorders and Posttraumatic Stress Disorder - p. 1573 176. Chapter 164: Affective Disorders - p. 1584 177. Chapter 165: Schizophrenia and Sleep - p. 1591 178. Chapter 166: Substance Abuse - p. 1600 179. Section 19. Dentistry and Otorhinolaryngology - p. 1607.e5 180. Chapter 167: Dentistry and Otorhinolaryngology in Sleep Medicine - p. 1608 181. Chapter 168: Oronasopharyngeal Growth and Malformations with Orthodontic Management - p. 1610 182. Chapter 169: Sleep Bruxism - p. 1631 183. Chapter 170: Assessment of Sleep Bruxism - p. 1636 184. Chapter 171: Management of Sleep Bruxism - p. 1645 185. Chapter 172: Orofacial Pain/Temporomandibular Disorders in Relation to Sleep Bruxism and Breathing Disorders - p. 1651 186. Chapter 173: Oral Appliances for the Treatment of Sleep-Disordered Breathing - p. 1657 187. Chapter 174: Anesthesia in Upper Airway Surgery - p. 1671 188. Chapter 175: Upper Airway Surgery to Treat Obstructive Sleep-Disordered Breathing - p. 1677 189. Chapter 176: Pharmacotherapy and Behavioral, Complementary, and Alternative Medicine for Sleep Bruxism - p. 1692 190. Section 20. From Childhood to Adulthood - p. 1698.e5 191. Chapter 177: Overview - p. 1699 192. Chapter 178: Sleep-Related Breathing Disorders in Children - p. 1702 193. Chapter 179: Neuromuscular and Neurological Disorders - p. 1707 194. Chapter 180: Transitional Care for Adolescents with Narcolepsy and Other Central Disorders of Hypersomnolence - p. 1714 195. Chapter 181: Congenital Heart Disease - p. 1722 196. Chapter 182: Sleep in Intersex and Transgender Individuals - p. 1727 197. Section 21. Sleep in Women - p. 1730.e3 198. Chapter 183: Introduction - p. 1731 199. Chapter 184: Sex Effects and Differences in Circadian Rhythms and Sleep - p. 1734 200. Chapter 185: The Menstrual Cycle, Sleep, and Circadian Rhythms - p. 1742 201. Chapter 186: Sleep and Sleep Disorders Associated with Pregnancy - p. 1751 202. Chapter 187: Sleep-Disordered Breathing in Pregnancy - p. 1764 203. Chapter 188: Postpartum Period and Early Parenthood - p. 1773 204. Chapter 189: Sleep and Menopause - p. 1781 205. Section 22. Sleep Medicine in the Elderly - p. 1792.e6 206. Chapter 190: Introduction - p. 1793 207. Chapter 191: Psychiatric and Medical Comorbidities and Effects of Medications in Older Adults - p. 1795 208. Chapter 192: Obstructive Sleep Apnea in Older Adults - p. 1807 209. Chapter 193: Insomnia in Older Adults - p. 1814 210. Chapter 194: Circadian Rhythms in Older Adults - p. 1821 211. Chapter 195: Sleep in Long-Term Care Settings - p. 1825 212. Section 23. Methodology - p. 1834.e6 213. Chapter 196: Section Introduction - p. 1835 214. Chapter 197: Sleep Stage Scoring - p. 1839 215. Chapter 198: Central Nervous System Arousals and the Cyclic Alternating Pattern - p. 1848 216. Chapter 199: Neurologic Monitoring Techniques - p. 1857 217. Chapter 200: Monitoring Techniques for Evaluating Suspected Sleep-Related Breathing and Cardiovascular Disorders - p. 1867 218. Chapter 201: Sleep Telemedicine and Remote PAP Adherence Monitoring - p. 1882 219. Chapter 202: Cardiopulmonary Coupling - p. 1891 220. Chapter 203: Pulse Wave Analysis - p. 1902 221. Chapter 204: Recording and Scoring Sleep-Related Movements - p. 1911 222. Chapter 205: Home Sleep Testing for Sleep-Related Breathing Disorders - p. 1925 223. Chapter 206: Consumer Sleep Tracking - p. 1930 224. Chapter 207: Evaluating Sleepiness and Fatigue - p. 1941 225. Chapter 208: The Assessment of Insomnia - p. 1951 226. Chapter 209: Surveys, Sampling, and Polling Methods for Sleep and Public Health - p. 1966 227. Chapter 210: Techniques for Clinical Assessment of Circadian Rhythm Disorders - p. 1974 228. Chapter 211: Actigraphy Methods and Technical Issues - p. 1984 229. Chapter 212: Imaging - p. 1992 230. Section 24. Late Breaking - p. 1998.e3 231. Chapter 213: COVID-19 and Sleep - p. 1999 232. Index - p. I-1