1. Introduction - p. 1 2. • Chapter 1 Ruminant History, Physical Examination, Welfare Assessment, and Records - p. 2 3. • Chapter 2 Equine History, Physical Examination, Records, and Recognizing Abuse or Neglect in Patients* - p. 14 4. Part 2 Manifestations of Disease - p. 22.e1 5. Introduction - p. 23 6. • Chapter 3 Pain - p. 24 7. • Chapter 4 Alterations in Body Temperature - p. 33 8. • Chapter 5 Alterations in Respiratory Function - p. 43 9. Cough - p. 43 10. Nasal Discharge - p. 51 11. Epistaxis and Hemoptysis - p. 57 12. Tachypnea - p. 60 13. Respiratory Distress (Dyspnea) - p. 60 14. Cyanosis - p. 68 15. Abnormal Respiratory Noise (Stridor) - p. 71 16. Exercise Intolerance and Poor Performance in Horses - p. 75 17. References - p. 81.e1 18. • Chapter 6 Alterations in Cardiovascular and Hemolymphatic Systems* - p. 82 19. • Chapter 7 Alterations in Alimentary and Hepatic Function - p. 95 20. • Chapter 8 Localization and Differentiation of Neurologic Diseases - p. 116 21. • Chapter 9 Alterations in Body Weight or Size - p. 141 22. • Chapter 10 Alterations in Urinary Function - p. 166 23. • Chapter 11 Alterations in the Skin* - p. 174 24. • Chapter 12 Alterations in Sexual Function - p. 189 25. • Chapter 13 Musculoskeletal Abnormalities - p. 212 26. • Chapter 14 Collapse and Sudden Death - p. 227 27. Part 3 Disorders and Management of the Neonate - p. 235.e1 28. Introduction - p. 236 29. • Chapter 15 The Equine Peripartum Period - p. 237 30. • Chapter 16 Assessment of the Newborn Foal - p. 247 31. • Chapter 17 Manifestations and Management of Disease in Neonatal Foals - p. 262 32. General Principles of Treatment and Care of the Abnormal Foal - p. 262 33. Sepsis - p. 267 34. Septic Arthritis and Osteomyelitis - p. 274 35. Noninfectious Causes of Lameness - p. 280 36. Seizures - p. 281 37. Neonatal Encephalopathy - p. 281 38. Other Neurologic Conditions - p. 288 39. Anemia - p. 289 40. Maturity - p. 290 41. Respiration - p. 294 42. Diarrhea in Neonatal Foals - p. 299 43. References - p. 306.e1 44. • Chapter 18 The Peripartum Ruminant - p. 307 45. • Chapter 19 Initial Management and Clinical Investigation of Neonatal Ruminants - p. 315 46. • Chapter 20 Manifestations and Management of Disease in Neonatal Ruminants - p. 335 47. Weakness and/or Depressed Mentation - p. 335 48. Respiratory Difficulty - p. 343 49. Abdominal Distention - p. 347 50. Diarrhea - p. 351 51. Lameness and Reluctance to Walk - p. 378 52. Umbilical Enlargement - p. 379 53. Anemia - p. 380 54. Fever - p. 380 55. Cyanosis - p. 380 56. Heart Murmur - p. 381 57. Icterus - p. 381 58. Bleeding Disorders - p. 381 59. Failure to Thrive: Cachexia and Weak Calf Syndrome - p. 381 60. References - p. 381.e1 61. • Chapter 21 Colostrum and Milk Replacers - p. 382 62. Part 4 Collection of Samples and Interpretation of Laboratory Tests - p. 393.e2 63. Introduction - p. 394 64. • Chapter 22 Clinical Chemistry Tests* - p. 395 65. • Chapter 23 Collection and Submission of Samples for Hematologic and Cytologic Evaluation* - p. 421 66. • Chapter 24 Alterations in the Erythron - p. 424 67. • Chapter 25 Alterations in the Leukogram* - p. 429 68. • Chapter 26 Alterations in Blood Proteins - p. 435 69. • Chapter 27 Alterations in Hemostasis - p. 442 70. • Chapter 28 Collection and Analysis of Bone Marrow - p. 449 71. • Chapter 29 Molecular Diagnostics - p. 462 72. Part 5 Disorders of the Organ Systems - p. 476.e3 73. Introduction - p. 477 74. • Chapter 30 Diseases of the Cardiovascular System* - p. 478 75. Performing the Electrocardiogram - p. 478 76. Use of Echocardiography in Large Animals - p. 479 77. Cardiac Catheterization in Large Animals - p. 481 78. Congenital Cardiovascular Disease - p. 482 79. Valvular Heart Disease - p. 488 80. Brisket Disease, Cor Pulmonale, and Pulmonary Hypertension - p. 493 81. Myocardial Disease: Myocarditis and Cardiomyopathy - p. 495 82. Pericarditis - p. 499 83. Cardiac Tumors - p. 503 84. Vascular Disease: Aneurysms, Thrombosis, and Embolism - p. 505 85. Atrial Fibrillation - p. 508 86. Ventricular Tachycardia - p. 512 87. References - p. 514.e1 88. • Chapter 31 Diseases of the Respiratory System - p. 515 89. Disorders of the Lung - p. 526 90. Diseases of Lymph Nodes, Vasculature, and Pharynx - p. 609 91. Guttural Pouch Diseases - p. 614 92. Diseases of the Paranasal Sinuses - p. 618 93. Disorders of the Equine Soft Palate - p. 622 94. Disorders of the Trachea - p. 625 95. Upper Respiratory Tract Diseases* - p. 636 96. Diseases of the Sinuses* - p. 639 97. Diseases of the Pharynx, Larynx, and Trachea* - p. 641 98. Lower Respiratory Tract Diseases* - p. 645 99. The Interstitial Pneumonias* - p. 679 100. Chronic Progressive Pneumonias of Sheep and Goats - p. 687 101. Parasitic Bronchitis and Pneumonia* - p. 691 102. Bovine Tuberculosis - p. 695 103. Other Pneumonias* - p. 698 104. Diseases of the Thoracic Wall and Cavity* - p. 699 105. Miscellaneous Conditions* - p. 701 106. References - p. 701.e1 107. Color Plates - p. 701.e41 108. • Chapter 32 Diseases of the Alimentary Tract - p. 702 109. Examination and Imaging of the Equine Alimentary System - p. 702 110. Ruminant Alimentary Disease - p. 804 111. References - p. 920.e1 112. Color Plates - p. 920.e34 113. • Chapter 33 Diseases of the Hepatobiliary System - p. 921 114. Diagnosis of Liver Disease* - p. 921 115. Infectious, Toxic, and Parasitic Liver Disease - p. 927 116. Hepatic Lipidosis* - p. 942 117. Congenital Hyperbilirubinemia - p. 948 118. Miscellaneous Liver Diseases - p. 948 119. Gallbladder and Biliary Tract Disease - p. 951 120. Therapy of Liver Failure - p. 952 121. Pancreatic Disease - p. 954 122. References - p. 955.e1 123. • Chapter 34 Diseases of the Renal System - p. 956 124. Acute Renal Failure - p. 956 125. Chronic Renal Failure - p. 963 126. Ulcerative Posthitis and Vulvitis - p. 983 127. Urolithiasis - p. 984 128. Urachal Disorders - p. 991 129. Urinary Bladder Eversion and Prolapse - p. 992 130. Pelvic Entrapment of the Bladder - p. 992 131. Enzootic Hematuria - p. 993 132. Urinary Tract Infection - p. 994 133. Amyloidosis - p. 996 134. Glomerulonephritis - p. 996 135. Congenital Defects - p. 997 136. Neoplasia - p. 998 137. Hemolytic Uremic Syndrome - p. 998 138. Tubular Necrosis - p. 999 139. Leptospirosis - p. 1002 140. References - p. 1005.e1 141. • Chapter 35 Diseases of the Nervous System - p. 1006 142. Cerebrospinal Fluid - p. 1006 143. Electrodiagnostic Testing - p. 1008 144. Diseases Manifesting Principally With Forebrain Dysfunction or Multiple-Level Brain Dysfunction - p. 1013 145. Diseases Manifesting Principally With Brainstem and Cranial Nerve Dysfunction - p. 1062 146. Diseases Manifesting Principally With Spinal Cord or Peripheral Nerve Signs - p. 1079 147. References - p. 1117.e1 148. • Chapter 36 Mammary Gland Health and Disorders - p. 1118 149. Mammary Gland Health of Dairy Cattle - p. 1118 150. Economic Impact of Mastitis of Dairy Cattle - p. 1118 151. Anatomic Structures of the Bovine Mammary Gland - p. 1119 152. Diagnosis and Detection of Mastitis - p. 1122 153. Prevention and Control of Mastitis - p. 1134 154. Mastitis Therapy: Antimicrobial Drugs - p. 1138 155. Mastitis in Beef Cows - p. 1147 156. Mastitis in Small Ruminants - p. 1147 157. Mastitis in Horses - p. 1149 158. References - p. 1150.e1 159. • Chapter 37 Diseases of the Hematopoietic and Hemolymphatic Systems - p. 1151 160. Diseases Associated With Blood Loss or Hemostatic Dysfunction - p. 1151 161. Hemoperitoneum in Horses - p. 1152 162. Chronic Blood Loss - p. 1152 163. Gastric Ulceration - p. 1153 164. Hemostatic Dysfunction - p. 1153 165. Inherited Coagulation Disorders - p. 1154 166. Thrombasthenias - p. 1156 167. Acquired Hemostatic Disorders - p. 1157 168. Anaplasma Phagocytophila Infection in Horses - p. 1158 169. Thrombocytopenia - p. 1159 170. Disorders of Coagulation Factors - p. 1160 171. Diseases Associated With Increased Erythrocyte Destruction (Hemolytic Anemia) - p. 1163 172. Bovine Anaplasmosis - p. 1164 173. Babesiosis - p. 1165 174. Haemobartonellosis (Eperythrozoonosis) - p. 1168 175. Theileriasis - p. 1168 176. Leptospirosis - p. 1169 177. Bacillary Hemoglobinuria (Red Water) - p. 1169 178. Equine Infectious Anemia - p. 1169 179. Autoimmune Hemolytic Anemia - p. 1171 180. Neonatal Isoerythrolysis in Horse and Mule Foals - p. 1172 181. Intravascular Hemolysis Following Cutaneous Burns - p. 1173 182. l-Tryptophan-Indol Intoxication - p. 1174 183. Water Intoxication - p. 1174 184. Postparturient Hemoglobinuria - p. 1174 185. Hemolytic Syndrome in Horses With Liver Failure - p. 1176 186. Congenital Erythropoietic Porphyria - p. 1176 187. Depression Anemia - p. 1177 188. Iron Deficiency Anemia - p. 1177 189. Vitamin B12 and Folic Acid Deficiency - p. 1178 190. Anemia of Inflammatory Disease - p. 1178 191. Anemia Secondary to Organ Dysfunction - p. 1178 192. Myeloid and Megakaryocytic Bone Marrow Hypoplasia - p. 1179 193. Aplastic Anemia - p. 1179 194. Paradoxical Erythroid Hypoplasia - p. 1179 195. Erythrocytosis (Polycythemia) - p. 1179 196. Bovine Lymphoma - p. 1180 197. Lymphoma in Horses - p. 1184 198. Leukemia in the Horse - p. 1186 199. Myeloma in the Horse - p. 1187 200. Lymphangioma in the Horse - p. 1188 201. Anthrax - p. 1188 202. Lyme Disease - p. 1190 203. Tularemia - p. 1191 204. Corynebacterium pseudotuberculosis Infection - p. 1192 205. References - p. 1196.e1 206. • Chapter 38 Diseases of the Bones, Joints, and Connective Tissues - p. 1197 207. Physitis (Epiphysitis) - p. 1197 208. Osteochondrosis - p. 1198 209. Angular Limb Deformities - p. 1200 210. Ovine Hereditary Chondrodysplasia (Spider Lamb Syndrome) - p. 1205 211. Septic (Infectious) Arthritis and Osteomyelitis - p. 1207 212. Mycoplasma Polyarthritis in Goats - p. 1214 213. Caprine Arthritis Encephalitis Virus - p. 1215 214. Osteoarthritis - p. 1216 215. Sprains, Subluxations, and Luxations - p. 1219 216. Arthrogryposis - p. 1221 217. Ankylosis - p. 1222 218. Osteomyelitis - p. 1223 219. Heel and Foot Pain - p. 1226 220. Spondylitis and Diskospondylitis - p. 1233 221. Spondylosis - p. 1234 222. Laminitis - p. 1235 223. Fluorosis - p. 1239 224. Hypertrophic Osteopathy - p. 1240 225. Fescue Foot - p. 1241 226. Interdigital Necrobacillosis (Foot Rot) in Cattle - p. 1242 227. Infectious Foot Rot in Small Ruminants - p. 1243 228. Other Infectious Conditions of the Foot - p. 1244 229. Fistulous Withers - p. 1248 230. Flexural Limb Deformities - p. 1249 231. Tendinitis - p. 1252 232. Suspensory Ligament Desmitis - p. 1253 233. Fractures - p. 1255 234. Spontaneous Fractures in Ruminants - p. 1260 235. Dorsal Metacarpal Disease in the Horse - p. 1261 236. Silicate Associated Osteoporosis - p. 1263 237. Temporohyoid Osteoarthropathy - p. 1265 238. References - p. 1266.e1 239. • Chapter 39 Diseases of the Eye - p. 1267 240. Ophthalmic History and Examination* - p. 1267 241. Signs of Ocular Disease* - p. 1272 242. Ocular Trauma* - p. 1277 243. Infectious Ocular Diseases - p. 1282 244. Immune-Mediated Ocular Diseases - p. 1296 245. Ocular Parasites* - p. 1305 246. Ocular Neoplasia* - p. 1308 247. References - p. 1315.e1 248. Color Plates - p. 1315.e12 249. • Chapter 40 Diseases of the Skin* - p. 1316 250. Autoimmune Skin Disorders - p. 1316 251. Hypersensitivity Disorders - p. 1317 252. Bacterial Diseases - p. 1322 253. Viral Diseases - p. 1327 254. Fungal Diseases - p. 1329 255. Parasitic Skin Diseases - p. 1331 256. Tumors and Cysts - p. 1338 257. Environmental Diseases - p. 1344 258. Skin Disorders of Unknown or Genetic Origin - p. 1345 259. References - p. 1351.e1 260. Color Plates - p. 1351.e10 261. • Chapter 41 Endocrine and Metabolic Diseases - p. 1352 262. Pituitary and Hypothalamus - p. 1352 263. Adrenal Glands - p. 1358 264. Anhidrosis - p. 1361 265. Thyroid Gland - p. 1364 266. Equine Metabolic Syndrome - p. 1368 267. Endocrinopathic Laminitis - p. 1373 268. Parathyroid Gland, Calcium, and Phosphorus Regulation in Horses - p. 1376 269. Endocrine Dysfunction in Critical Illness - p. 1386 270. Macromineral and Bone Problems of Ruminants - p. 1392 271. Hyperketonemia in Dairy Cattle (Ketosis) - p. 1408 272. Bovine Somatotropin - p. 1414 273. References - p. 1420.e1 274. • Chapter 42 Diseases of Muscle - p. 1421 275. Classification of Muscle Disorders - p. 1424 276. Disorders of Muscle Tone - p. 1426 277. Nonexertional Rhabdomyolysis - p. 1432 278. Exertional Myopathies in Horses - p. 1444 279. Hereditary and Congenital Myopathies - p. 1454 280. References - p. 1455.e1 281. • Chapter 43 Diseases of the Reproductive System - p. 1456 282. Nonpathogenic Infertility - p. 1456 283. Infertility Caused by Abnormalities of the Female Genital Organs - p. 1464 284. Abnormalities of the Ovaries - p. 1466 285. Infertility Caused by Abnormalities of the Female Tubular Genitalia - p. 1471 286. Abortion - p. 1488 287. Infertility Caused by Diseases of the Penis and Prepuce - p. 1505 288. Infertility Caused by Diseases of the Scrotum and Testes - p. 1513 289. Infertility Caused by Diseases of the Spermatic Cord - p. 1516 290. Infertility Caused by Diseases of the Epididymis and Accessory Sex Glands - p. 1517 291. References - p. 1519.e1 292. Part 6 Preventive and Therapeutic Strategies - p. 1519.e10 293. Introduction - p. 1520 294. • Chapter 44 Critical Care and Fluid Therapy - p. 1521 295. • Chapter 45 Rational Antimicrobial Therapy - p. 1545 296. • Chapter 46 Biosecurity and Infection Control - p. 1563 297. • Chapter 47 Prevention, Detection, and Response to Transboundary (Foreign) Animal Diseases - p. 1593 298. • Chapter 48 Use of Biologics in the Prevention of Infectious Diseases - p. 1599 299. Current Concepts in Equine Vaccination and Infectious Disease Control - p. 1599 300. Ovine and Caprine Vaccination Programs - p. 1628 301. Bovine Vaccines and Herd Vaccination Programs - p. 1635 302. Bovine Herpesvirus Type 1: Infectious Bovine Rhinotracheitis Virus - p. 1641 303. Bovine Virus Diarrhea Virus Vaccines - p. 1645 304. Bovine Respiratory Syncytial Virus Vaccines - p. 1647 305. Parainfluenza Type 3 Virus Vaccines - p. 1648 306. Mannheimia haemolytica, Pasteurella multocida, Histophilus somni, and Bibersteinia trehalosi - p. 1649 307. Bovine Reproductive Disease Vaccines - p. 1653 308. Neonatal Calf Enteric Disease Vaccines - p. 1655 309. Bacterial Scours Vaccines - p. 1658 310. Clostridial Vaccines - p. 1661 311. Miscellaneous Bovine Rickettsial, Bacterial, and Viral Disease Vaccines - p. 1664 312. References - p. 1668.e1 313. • Chapter 49 Parasite Control Programs - p. 1669 314. Equine Parasitic Disease - p. 1669 315. Gastrointestinal Nematode Infections in Cattle - p. 1676 316. Gastrointestinal Nematode Infections in Sheep and Goats - p. 1680 317. Evaluation of Parasite Control Programs - p. 1685 318. Lungworm Infection in Large Animals - p. 1686 319. Coccidiosis in Food Animals - p. 1689 320. Anthelmintic Use - p. 1692 321. Anthelmintic Drugs (see Table 49.4), - p. 1692 322. References - p. 1693.e1 323. • Chapter 50 Nutrition of the Sick Animal - p. 1694 324. Part 7 Congenital, Hereditary, Immunologic, and Toxic Disorders - p. 1702.e2 325. Introduction - p. 1703 326. • Chapter 51 Genetic Disorders - p. 1704 327. • Chapter 52 Genetic Tests for Large Animals - p. 1709 328. • Chapter 53 Immunologic Disorders - p. 1717 329. Equine Immunologic Disorders - p. 1717 330. Diseases Caused by Allogeneic Incompatibilities (Horses and Ruminants) - p. 1751 331. Ruminant Immunologic Disorders - p. 1759 332. References - p. 1763.e1 333. • Chapter 54 Disorders Caused by Toxicants* - p. 1764 334. Poisonous Plants - p. 1766 335. Metals and Other Inorganic Compounds - p. 1793 336. Medications, Therapeutic Agents, and Illicit Substances - p. 1797 337. Pesticides and Rodenticides - p. 1802 338. References - p. 1809.e1 339. Color Plates - p. 1809.e7 340. Index - p. 1810 341. Endsheet 6 - p. IBC1 342. Endsheet 7 - p. IBC2
1. Introduction - p. 1 2. • Chapter 1 Ruminant History, Physical Examination, Welfare Assessment, and Records - p. 2 3. • Chapter 2 Equine History, Physical Examination, Records, and Recognizing Abuse or Neglect in Patients* - p. 14 4. Part 2 Manifestations of Disease - p. 22.e1 5. Introduction - p. 23 6. • Chapter 3 Pain - p. 24 7. • Chapter 4 Alterations in Body Temperature - p. 33 8. • Chapter 5 Alterations in Respiratory Function - p. 43 9. Cough - p. 43 10. Nasal Discharge - p. 51 11. Epistaxis and Hemoptysis - p. 57 12. Tachypnea - p. 60 13. Respiratory Distress (Dyspnea) - p. 60 14. Cyanosis - p. 68 15. Abnormal Respiratory Noise (Stridor) - p. 71 16. Exercise Intolerance and Poor Performance in Horses - p. 75 17. References - p. 81.e1 18. • Chapter 6 Alterations in Cardiovascular and Hemolymphatic Systems* - p. 82 19. • Chapter 7 Alterations in Alimentary and Hepatic Function - p. 95 20. • Chapter 8 Localization and Differentiation of Neurologic Diseases - p. 116 21. • Chapter 9 Alterations in Body Weight or Size - p. 141 22. • Chapter 10 Alterations in Urinary Function - p. 166 23. • Chapter 11 Alterations in the Skin* - p. 174 24. • Chapter 12 Alterations in Sexual Function - p. 189 25. • Chapter 13 Musculoskeletal Abnormalities - p. 212 26. • Chapter 14 Collapse and Sudden Death - p. 227 27. Part 3 Disorders and Management of the Neonate - p. 235.e1 28. Introduction - p. 236 29. • Chapter 15 The Equine Peripartum Period - p. 237 30. • Chapter 16 Assessment of the Newborn Foal - p. 247 31. • Chapter 17 Manifestations and Management of Disease in Neonatal Foals - p. 262 32. General Principles of Treatment and Care of the Abnormal Foal - p. 262 33. Sepsis - p. 267 34. Septic Arthritis and Osteomyelitis - p. 274 35. Noninfectious Causes of Lameness - p. 280 36. Seizures - p. 281 37. Neonatal Encephalopathy - p. 281 38. Other Neurologic Conditions - p. 288 39. Anemia - p. 289 40. Maturity - p. 290 41. Respiration - p. 294 42. Diarrhea in Neonatal Foals - p. 299 43. References - p. 306.e1 44. • Chapter 18 The Peripartum Ruminant - p. 307 45. • Chapter 19 Initial Management and Clinical Investigation of Neonatal Ruminants - p. 315 46. • Chapter 20 Manifestations and Management of Disease in Neonatal Ruminants - p. 335 47. Weakness and/or Depressed Mentation - p. 335 48. Respiratory Difficulty - p. 343 49. Abdominal Distention - p. 347 50. Diarrhea - p. 351 51. Lameness and Reluctance to Walk - p. 378 52. Umbilical Enlargement - p. 379 53. Anemia - p. 380 54. Fever - p. 380 55. Cyanosis - p. 380 56. Heart Murmur - p. 381 57. Icterus - p. 381 58. Bleeding Disorders - p. 381 59. Failure to Thrive: Cachexia and Weak Calf Syndrome - p. 381 60. References - p. 381.e1 61. • Chapter 21 Colostrum and Milk Replacers - p. 382 62. Part 4 Collection of Samples and Interpretation of Laboratory Tests - p. 393.e2 63. Introduction - p. 394 64. • Chapter 22 Clinical Chemistry Tests* - p. 395 65. • Chapter 23 Collection and Submission of Samples for Hematologic and Cytologic Evaluation* - p. 421 66. • Chapter 24 Alterations in the Erythron - p. 424 67. • Chapter 25 Alterations in the Leukogram* - p. 429 68. • Chapter 26 Alterations in Blood Proteins - p. 435 69. • Chapter 27 Alterations in Hemostasis - p. 442 70. • Chapter 28 Collection and Analysis of Bone Marrow - p. 449 71. • Chapter 29 Molecular Diagnostics - p. 462 72. Part 5 Disorders of the Organ Systems - p. 476.e3 73. Introduction - p. 477 74. • Chapter 30 Diseases of the Cardiovascular System* - p. 478 75. Performing the Electrocardiogram - p. 478 76. Use of Echocardiography in Large Animals - p. 479 77. Cardiac Catheterization in Large Animals - p. 481 78. Congenital Cardiovascular Disease - p. 482 79. Valvular Heart Disease - p. 488 80. Brisket Disease, Cor Pulmonale, and Pulmonary Hypertension - p. 493 81. Myocardial Disease: Myocarditis and Cardiomyopathy - p. 495 82. Pericarditis - p. 499 83. Cardiac Tumors - p. 503 84. Vascular Disease: Aneurysms, Thrombosis, and Embolism - p. 505 85. Atrial Fibrillation - p. 508 86. Ventricular Tachycardia - p. 512 87. References - p. 514.e1 88. • Chapter 31 Diseases of the Respiratory System - p. 515 89. Disorders of the Lung - p. 526 90. Diseases of Lymph Nodes, Vasculature, and Pharynx - p. 609 91. Guttural Pouch Diseases - p. 614 92. Diseases of the Paranasal Sinuses - p. 618 93. Disorders of the Equine Soft Palate - p. 622 94. Disorders of the Trachea - p. 625 95. Upper Respiratory Tract Diseases* - p. 636 96. Diseases of the Sinuses* - p. 639 97. Diseases of the Pharynx, Larynx, and Trachea* - p. 641 98. Lower Respiratory Tract Diseases* - p. 645 99. The Interstitial Pneumonias* - p. 679 100. Chronic Progressive Pneumonias of Sheep and Goats - p. 687 101. Parasitic Bronchitis and Pneumonia* - p. 691 102. Bovine Tuberculosis - p. 695 103. Other Pneumonias* - p. 698 104. Diseases of the Thoracic Wall and Cavity* - p. 699 105. Miscellaneous Conditions* - p. 701 106. References - p. 701.e1 107. Color Plates - p. 701.e41 108. • Chapter 32 Diseases of the Alimentary Tract - p. 702 109. Examination and Imaging of the Equine Alimentary System - p. 702 110. Ruminant Alimentary Disease - p. 804 111. References - p. 920.e1 112. Color Plates - p. 920.e34 113. • Chapter 33 Diseases of the Hepatobiliary System - p. 921 114. Diagnosis of Liver Disease* - p. 921 115. Infectious, Toxic, and Parasitic Liver Disease - p. 927 116. Hepatic Lipidosis* - p. 942 117. Congenital Hyperbilirubinemia - p. 948 118. Miscellaneous Liver Diseases - p. 948 119. Gallbladder and Biliary Tract Disease - p. 951 120. Therapy of Liver Failure - p. 952 121. Pancreatic Disease - p. 954 122. References - p. 955.e1 123. • Chapter 34 Diseases of the Renal System - p. 956 124. Acute Renal Failure - p. 956 125. Chronic Renal Failure - p. 963 126. Ulcerative Posthitis and Vulvitis - p. 983 127. Urolithiasis - p. 984 128. Urachal Disorders - p. 991 129. Urinary Bladder Eversion and Prolapse - p. 992 130. Pelvic Entrapment of the Bladder - p. 992 131. Enzootic Hematuria - p. 993 132. Urinary Tract Infection - p. 994 133. Amyloidosis - p. 996 134. Glomerulonephritis - p. 996 135. Congenital Defects - p. 997 136. Neoplasia - p. 998 137. Hemolytic Uremic Syndrome - p. 998 138. Tubular Necrosis - p. 999 139. Leptospirosis - p. 1002 140. References - p. 1005.e1 141. • Chapter 35 Diseases of the Nervous System - p. 1006 142. Cerebrospinal Fluid - p. 1006 143. Electrodiagnostic Testing - p. 1008 144. Diseases Manifesting Principally With Forebrain Dysfunction or Multiple-Level Brain Dysfunction - p. 1013 145. Diseases Manifesting Principally With Brainstem and Cranial Nerve Dysfunction - p. 1062 146. Diseases Manifesting Principally With Spinal Cord or Peripheral Nerve Signs - p. 1079 147. References - p. 1117.e1 148. • Chapter 36 Mammary Gland Health and Disorders - p. 1118 149. Mammary Gland Health of Dairy Cattle - p. 1118 150. Economic Impact of Mastitis of Dairy Cattle - p. 1118 151. Anatomic Structures of the Bovine Mammary Gland - p. 1119 152. Diagnosis and Detection of Mastitis - p. 1122 153. Prevention and Control of Mastitis - p. 1134 154. Mastitis Therapy: Antimicrobial Drugs - p. 1138 155. Mastitis in Beef Cows - p. 1147 156. Mastitis in Small Ruminants - p. 1147 157. Mastitis in Horses - p. 1149 158. References - p. 1150.e1 159. • Chapter 37 Diseases of the Hematopoietic and Hemolymphatic Systems - p. 1151 160. Diseases Associated With Blood Loss or Hemostatic Dysfunction - p. 1151 161. Hemoperitoneum in Horses - p. 1152 162. Chronic Blood Loss - p. 1152 163. Gastric Ulceration - p. 1153 164. Hemostatic Dysfunction - p. 1153 165. Inherited Coagulation Disorders - p. 1154 166. Thrombasthenias - p. 1156 167. Acquired Hemostatic Disorders - p. 1157 168. Anaplasma Phagocytophila Infection in Horses - p. 1158 169. Thrombocytopenia - p. 1159 170. Disorders of Coagulation Factors - p. 1160 171. Diseases Associated With Increased Erythrocyte Destruction (Hemolytic Anemia) - p. 1163 172. Bovine Anaplasmosis - p. 1164 173. Babesiosis - p. 1165 174. Haemobartonellosis (Eperythrozoonosis) - p. 1168 175. Theileriasis - p. 1168 176. Leptospirosis - p. 1169 177. Bacillary Hemoglobinuria (Red Water) - p. 1169 178. Equine Infectious Anemia - p. 1169 179. Autoimmune Hemolytic Anemia - p. 1171 180. Neonatal Isoerythrolysis in Horse and Mule Foals - p. 1172 181. Intravascular Hemolysis Following Cutaneous Burns - p. 1173 182. l-Tryptophan-Indol Intoxication - p. 1174 183. Water Intoxication - p. 1174 184. Postparturient Hemoglobinuria - p. 1174 185. Hemolytic Syndrome in Horses With Liver Failure - p. 1176 186. Congenital Erythropoietic Porphyria - p. 1176 187. Depression Anemia - p. 1177 188. Iron Deficiency Anemia - p. 1177 189. Vitamin B12 and Folic Acid Deficiency - p. 1178 190. Anemia of Inflammatory Disease - p. 1178 191. Anemia Secondary to Organ Dysfunction - p. 1178 192. Myeloid and Megakaryocytic Bone Marrow Hypoplasia - p. 1179 193. Aplastic Anemia - p. 1179 194. Paradoxical Erythroid Hypoplasia - p. 1179 195. Erythrocytosis (Polycythemia) - p. 1179 196. Bovine Lymphoma - p. 1180 197. Lymphoma in Horses - p. 1184 198. Leukemia in the Horse - p. 1186 199. Myeloma in the Horse - p. 1187 200. Lymphangioma in the Horse - p. 1188 201. Anthrax - p. 1188 202. Lyme Disease - p. 1190 203. Tularemia - p. 1191 204. Corynebacterium pseudotuberculosis Infection - p. 1192 205. References - p. 1196.e1 206. • Chapter 38 Diseases of the Bones, Joints, and Connective Tissues - p. 1197 207. Physitis (Epiphysitis) - p. 1197 208. Osteochondrosis - p. 1198 209. Angular Limb Deformities - p. 1200 210. Ovine Hereditary Chondrodysplasia (Spider Lamb Syndrome) - p. 1205 211. Septic (Infectious) Arthritis and Osteomyelitis - p. 1207 212. Mycoplasma Polyarthritis in Goats - p. 1214 213. Caprine Arthritis Encephalitis Virus - p. 1215 214. Osteoarthritis - p. 1216 215. Sprains, Subluxations, and Luxations - p. 1219 216. Arthrogryposis - p. 1221 217. Ankylosis - p. 1222 218. Osteomyelitis - p. 1223 219. Heel and Foot Pain - p. 1226 220. Spondylitis and Diskospondylitis - p. 1233 221. Spondylosis - p. 1234 222. Laminitis - p. 1235 223. Fluorosis - p. 1239 224. Hypertrophic Osteopathy - p. 1240 225. Fescue Foot - p. 1241 226. Interdigital Necrobacillosis (Foot Rot) in Cattle - p. 1242 227. Infectious Foot Rot in Small Ruminants - p. 1243 228. Other Infectious Conditions of the Foot - p. 1244 229. Fistulous Withers - p. 1248 230. Flexural Limb Deformities - p. 1249 231. Tendinitis - p. 1252 232. Suspensory Ligament Desmitis - p. 1253 233. Fractures - p. 1255 234. Spontaneous Fractures in Ruminants - p. 1260 235. Dorsal Metacarpal Disease in the Horse - p. 1261 236. Silicate Associated Osteoporosis - p. 1263 237. Temporohyoid Osteoarthropathy - p. 1265 238. References - p. 1266.e1 239. • Chapter 39 Diseases of the Eye - p. 1267 240. Ophthalmic History and Examination* - p. 1267 241. Signs of Ocular Disease* - p. 1272 242. Ocular Trauma* - p. 1277 243. Infectious Ocular Diseases - p. 1282 244. Immune-Mediated Ocular Diseases - p. 1296 245. Ocular Parasites* - p. 1305 246. Ocular Neoplasia* - p. 1308 247. References - p. 1315.e1 248. Color Plates - p. 1315.e12 249. • Chapter 40 Diseases of the Skin* - p. 1316 250. Autoimmune Skin Disorders - p. 1316 251. Hypersensitivity Disorders - p. 1317 252. Bacterial Diseases - p. 1322 253. Viral Diseases - p. 1327 254. Fungal Diseases - p. 1329 255. Parasitic Skin Diseases - p. 1331 256. Tumors and Cysts - p. 1338 257. Environmental Diseases - p. 1344 258. Skin Disorders of Unknown or Genetic Origin - p. 1345 259. References - p. 1351.e1 260. Color Plates - p. 1351.e10 261. • Chapter 41 Endocrine and Metabolic Diseases - p. 1352 262. Pituitary and Hypothalamus - p. 1352 263. Adrenal Glands - p. 1358 264. Anhidrosis - p. 1361 265. Thyroid Gland - p. 1364 266. Equine Metabolic Syndrome - p. 1368 267. Endocrinopathic Laminitis - p. 1373 268. Parathyroid Gland, Calcium, and Phosphorus Regulation in Horses - p. 1376 269. Endocrine Dysfunction in Critical Illness - p. 1386 270. Macromineral and Bone Problems of Ruminants - p. 1392 271. Hyperketonemia in Dairy Cattle (Ketosis) - p. 1408 272. Bovine Somatotropin - p. 1414 273. References - p. 1420.e1 274. • Chapter 42 Diseases of Muscle - p. 1421 275. Classification of Muscle Disorders - p. 1424 276. Disorders of Muscle Tone - p. 1426 277. Nonexertional Rhabdomyolysis - p. 1432 278. Exertional Myopathies in Horses - p. 1444 279. Hereditary and Congenital Myopathies - p. 1454 280. References - p. 1455.e1 281. • Chapter 43 Diseases of the Reproductive System - p. 1456 282. Nonpathogenic Infertility - p. 1456 283. Infertility Caused by Abnormalities of the Female Genital Organs - p. 1464 284. Abnormalities of the Ovaries - p. 1466 285. Infertility Caused by Abnormalities of the Female Tubular Genitalia - p. 1471 286. Abortion - p. 1488 287. Infertility Caused by Diseases of the Penis and Prepuce - p. 1505 288. Infertility Caused by Diseases of the Scrotum and Testes - p. 1513 289. Infertility Caused by Diseases of the Spermatic Cord - p. 1516 290. Infertility Caused by Diseases of the Epididymis and Accessory Sex Glands - p. 1517 291. References - p. 1519.e1 292. Part 6 Preventive and Therapeutic Strategies - p. 1519.e10 293. Introduction - p. 1520 294. • Chapter 44 Critical Care and Fluid Therapy - p. 1521 295. • Chapter 45 Rational Antimicrobial Therapy - p. 1545 296. • Chapter 46 Biosecurity and Infection Control - p. 1563 297. • Chapter 47 Prevention, Detection, and Response to Transboundary (Foreign) Animal Diseases - p. 1593 298. • Chapter 48 Use of Biologics in the Prevention of Infectious Diseases - p. 1599 299. Current Concepts in Equine Vaccination and Infectious Disease Control - p. 1599 300. Ovine and Caprine Vaccination Programs - p. 1628 301. Bovine Vaccines and Herd Vaccination Programs - p. 1635 302. Bovine Herpesvirus Type 1: Infectious Bovine Rhinotracheitis Virus - p. 1641 303. Bovine Virus Diarrhea Virus Vaccines - p. 1645 304. Bovine Respiratory Syncytial Virus Vaccines - p. 1647 305. Parainfluenza Type 3 Virus Vaccines - p. 1648 306. Mannheimia haemolytica, Pasteurella multocida, Histophilus somni, and Bibersteinia trehalosi - p. 1649 307. Bovine Reproductive Disease Vaccines - p. 1653 308. Neonatal Calf Enteric Disease Vaccines - p. 1655 309. Bacterial Scours Vaccines - p. 1658 310. Clostridial Vaccines - p. 1661 311. Miscellaneous Bovine Rickettsial, Bacterial, and Viral Disease Vaccines - p. 1664 312. References - p. 1668.e1 313. • Chapter 49 Parasite Control Programs - p. 1669 314. Equine Parasitic Disease - p. 1669 315. Gastrointestinal Nematode Infections in Cattle - p. 1676 316. Gastrointestinal Nematode Infections in Sheep and Goats - p. 1680 317. Evaluation of Parasite Control Programs - p. 1685 318. Lungworm Infection in Large Animals - p. 1686 319. Coccidiosis in Food Animals - p. 1689 320. Anthelmintic Use - p. 1692 321. Anthelmintic Drugs (see Table 49.4), - p. 1692 322. References - p. 1693.e1 323. • Chapter 50 Nutrition of the Sick Animal - p. 1694 324. Part 7 Congenital, Hereditary, Immunologic, and Toxic Disorders - p. 1702.e2 325. Introduction - p. 1703 326. • Chapter 51 Genetic Disorders - p. 1704 327. • Chapter 52 Genetic Tests for Large Animals - p. 1709 328. • Chapter 53 Immunologic Disorders - p. 1717 329. Equine Immunologic Disorders - p. 1717 330. Diseases Caused by Allogeneic Incompatibilities (Horses and Ruminants) - p. 1751 331. Ruminant Immunologic Disorders - p. 1759 332. References - p. 1763.e1 333. • Chapter 54 Disorders Caused by Toxicants* - p. 1764 334. Poisonous Plants - p. 1766 335. Metals and Other Inorganic Compounds - p. 1793 336. Medications, Therapeutic Agents, and Illicit Substances - p. 1797 337. Pesticides and Rodenticides - p. 1802 338. References - p. 1809.e1 339. Color Plates - p. 1809.e7 340. Index - p. 1810 341. Endsheet 6 - p. IBC1 342. Endsheet 7 - p. IBC2
