Discovery and Development of Anti-inflammatory Agents from Natural Products, the latest volume in the Natural Product Drug Discovery series, presents cutting-edge research advances in the field of bioactive natural products and natural drug formulations, with this volume focusing on molecules of natural origin and their synthetic analogues that have the potential to act against the pathogens responsible for inflammatory diseases. All aspects of each are covered, including isolations and structure elucidations, in vitro and in vivo biological activity, synthetic optimization, investigations of pharmacodynamics and kinetics, and the structure-activity relationships of anti-inflammatory natural products.
Written by active researchers and leading experts, this book brings together an overview of current discoveries and trends in this field. It will be a valuable resource for researchers working to discover promising leads for the development of pharmaceuticals in the prevention and treatment of anti-inflammatory diseases.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iv 5. Dedication - p. v 6. Contributors - p. xiii 7. Editor Biography - p. xv 8. Foreword - p. xix 9. Preface - p. xxi 10. Chapter 1. Discovery and development of anti-inflammatory agents from natural products: An overview - p. 1 11. Chapter 2. Curcumin: Current evidence of its therapeutic potential as a lead candidate for anti-inflammatory drugs—an overview - p. 7 12. Chapter 3. Anti-inflammatory efficacy of some potentially bioactive natural products against rheumatoid arthritis - p. 61 13. Chapter 4. Natural anti-inflammatory agents for the management of osteoarthritis - p. 101 14. Chapter 5. Portrait of the synthesis of some potent anti-inflammatory natural products - p. 141 15. Chapter 6. Recent developments in the anti-inflammatory potential of sesquiterpene lactones and their semisynthetic analogs - p. 185 16. Chapter 7. Hesperetin and naringenin: Protective effects against metabolic syndrome–associated inflammation - p. 207 17. Chapter 8. Therapeutic implications of anti-inflammatory natural products in Alzheimer’s disease - p. 241 18. Chapter 9. Anti-inflammatory effects of probiotics - p. 259 19. Chapter 10. 6-Gingerol: A therapeutically potent lead candidate in anti-inflammatory drug discovery - p. 283 20. Index - p. 297
Discovery and Development of Anti-inflammatory Agents from Natural Products, the latest volume in the Natural Product Drug Discovery series, presents cutting-edge research advances in the field of bioactive natural products and natural drug formulations, with this volume focusing on molecules of natural origin and their synthetic analogues that have the potential to act against the pathogens responsible for inflammatory diseases. All aspects of each are covered, including isolations and structure elucidations, in vitro and in vivo biological activity, synthetic optimization, investigations of pharmacodynamics and kinetics, and the structure-activity relationships of anti-inflammatory natural products.
Written by active researchers and leading experts, this book brings together an overview of current discoveries and trends in this field. It will be a valuable resource for researchers working to discover promising leads for the development of pharmaceuticals in the prevention and treatment of anti-inflammatory diseases.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iv 5. Dedication - p. v 6. Contributors - p. xiii 7. Editor Biography - p. xv 8. Foreword - p. xix 9. Preface - p. xxi 10. Chapter 1. Discovery and development of anti-inflammatory agents from natural products: An overview - p. 1 11. Chapter 2. Curcumin: Current evidence of its therapeutic potential as a lead candidate for anti-inflammatory drugs—an overview - p. 7 12. Chapter 3. Anti-inflammatory efficacy of some potentially bioactive natural products against rheumatoid arthritis - p. 61 13. Chapter 4. Natural anti-inflammatory agents for the management of osteoarthritis - p. 101 14. Chapter 5. Portrait of the synthesis of some potent anti-inflammatory natural products - p. 141 15. Chapter 6. Recent developments in the anti-inflammatory potential of sesquiterpene lactones and their semisynthetic analogs - p. 185 16. Chapter 7. Hesperetin and naringenin: Protective effects against metabolic syndrome–associated inflammation - p. 207 17. Chapter 8. Therapeutic implications of anti-inflammatory natural products in Alzheimer’s disease - p. 241 18. Chapter 9. Anti-inflammatory effects of probiotics - p. 259 19. Chapter 10. 6-Gingerol: A therapeutically potent lead candidate in anti-inflammatory drug discovery - p. 283 20. Index - p. 297