Trust Lehne’s to make pharmacology more approachable! Known for its clear explanations of drug prototypes and how they work, Lehne's Pharmacology for Nursing Care, 11th Edition provides a solid understanding of key drugs and their implications for nursing care. A perennial student favorite, this book simplifies complex pharmacology concepts, using large and small print to distinguish need-to-know drug content from the material that’s merely nice to know. It also includes in-depth coverage of physiology, pathophysiology and drug therapy. Written by noted nursing educators Jacqueline Rosenjack Burchum and Laura Rosenthal, this text helps you understand and apply pharmacology principles as opposed to simply memorizing drug facts.
1. Unit I: Introduction - p. 1 2. Chapter 1. Orientation to Pharmacology - p. 1a 3. Chapter 2. Application of Pharmacology in Nursing Practice - p. 5 4. Chapter 3. Drug Regulation, Development, Names, and Information - p. 14 5. Unit II: Basic Principles of Pharmacology - p. 24 6. Chapter 4. Pharmacokinetics - p. 24a 7. Chapter 5. Pharmacodynamics - p. 44 8. Chapter 6. Drug Interactions - p. 55 9. Chapter 7. Adverse Drug Reactions and Medication Errors - p. 63 10. Chapter 8. Individual Variation in Drug Responses - p. 74 11. Chapter 9. Genetic and Genomic Considerations - p. 79 12. Chapter 10. Introduction to Immunomodulators - p. 85 13. Unit III: Drug Therapy Across The Life Span - p. 90 14. Chapter 11. Drug Therapy During Pregnancy and Breast-Feeding - p. 90a 15. Chapter 12. Drug Therapy in Pediatric Patients - p. 98 16. Chapter 13. Drug Therapy in Older Adults - p. 102 17. Unit IV: Peripheral Nervous System Drugs - p. 108 18. Section 1: Introduction - p. 108a 19. Chapter 14. Basic Principles of Neuropharmacology - p. 108b 20. Chapter 15. Physiology of the Peripheral Nervous System - p. 113 21. Section 2: Cholinergic Drugs - p. 126 22. Chapter 16. Muscarinic Agonists - p. 126a 23. Chapter 17. Muscarinic Antagonists - p. 131 24. Chapter 18. Cholinesterase Inhibitors and Their Use in Myasthenia Gravis - p. 141 25. Chapter 19. Drugs That Block Nicotinic Cholinergic Transmission - p. 148 26. Section 3: Adrenergic Drugs - p. 157 27. Chapter 20. Adrenergic Agonists - p. 157a 28. Chapter 21. Adrenergic Antagonists - p. 170 29. Chapter 22. Indirect-Acting Antiadrenergic Agents - p. 183 30. Unit V: Central Nervous System Drugs - p. 188 31. Section 4: Introduction - p. 188a 32. Chapter 23. Introduction to Central Nervous System Pharmacology - p. 188b 33. Section 5: Drugs for Neurodegenerative Disorders - p. 191 34. Chapter 24. Drugs for Parkinson Disease - p. 191a 35. Chapter 25. Drugs for Alzheimer Disease - p. 209 36. Chapter 26. Drugs for Multiple Sclerosis - p. 216 37. Section 6: Neurologic Drugs - p. 234 38. Chapter 27. Drugs for Seizure Disorders - p. 234a 39. Chapter 28. Drugs for Muscle Spasm and Spasticity - p. 262 40. Section 7: Drugs for Pain - p. 271 41. Chapter 29. Local Anesthetics - p. 271a 42. Chapter 30. General Anesthetics - p. 277 43. Chapter 31. Opioid Analgesics, Opioid Antagonists, and Nonopioid Centrally Acting Analgesics - p. 286 44. Chapter 32. Pain Management in Patients With Cancer - p. 307 45. Chapter 33. Drugs for Headache - p. 323 46. Section 8: Psychotherapeutic Drugs - p. 334 47. Chapter 34. Antipsychotic Agents and Their Use in Schizophrenia - p. 334a 48. Chapter 35. Antidepressants - p. 351 49. Chapter 36. Drugs for Bipolar Disorder - p. 372 50. Chapter 37. Sedative-Hypnotic Drugs - p. 380 51. Chapter 38. Management of Anxiety Disorders - p. 395 52. Chapter 39. Central Nervous System Stimulants and Attention-Deficit/Hyperactivity Disorder - p. 402 53. Section 9: Substance Use Disorders - p. 412 54. Chapter 40. Substance Use Disorders I: Basic Considerations - p. 412a 55. Chapter 41. Substance Use Disorders II: Alcohol - p. 419 56. Chapter 42. Substance Use Disorders III: Nicotine - p. 430 57. Chapter 43. Substance Use Disorders IV: Major Drugs of Abuse Other Than Alcohol and Nicotine - p. 438 58. Unit VI: Drugs That Affect Fluid and Electrolyte Balance - p. 454 59. Chapter 44. Diuretics - p. 454a 60. Chapter 45. Agents Affecting the Volume and Ion Content of Body Fluids - p. 466 61. Unit VII: Drugs That Affect The Heart, Blood Vessels, and Blood - p. 471 62. Chapter 46. Review of Hemodynamics - p. 471a 63. Chapter 47. Drugs Acting on the Renin-Angiotensin-Aldosterone System - p. 477 64. Chapter 48. Calcium Channel Blockers - p. 492 65. Chapter 49. Vasodilators - p. 500 66. Chapter 50. Drugs for Hypertension - p. 505 67. Chapter 51. Drugs for Heart Failure - p. 523 68. Chapter 52. Antidysrhythmic Drugs - p. 540 69. Chapter 53. Drugs That Help Normalize Cholesterol and Triglyceride Levels - p. 559 70. Chapter 54. Drugs for Angina Pectoris - p. 581 71. Chapter 55. Anticoagulant, Antiplatelet, and Thrombolytic Drugs - p. 594 72. Chapter 56. Management of ST-Elevation Myocardial Infarction - p. 620 73. Chapter 57. Drugs for Hemophilia - p. 627 74. Chapter 58. Drugs for Deficiency Anemias - p. 635 75. Chapter 59. Hematopoietic Agents - p. 650 76. Unit VIII: Drugs for Endocrine Disorders - p. 660 77. Chapter 60. Drugs for Diabetes Mellitus - p. 660a 78. Chapter 61. Drugs for Thyroid Disorders - p. 694 79. Chapter 62. Drugs Related to Hypothalamic and Pituitary Function - p. 705 80. Chapter 63. Drugs for Disorders of the Adrenal Cortex - p. 713 81. Unit IX: Women’s Health - p. 720 82. Chapter 64. Estrogens and Progestins: Basic Pharmacology and Noncontraceptive Applications - p. 720a 83. Chapter 65. Birth Control - p. 734 84. Chapter 66. Drug Therapy for Infertility - p. 749 85. Chapter 67. Drugs That Affect Uterine Function - p. 757 86. Unit X: Men’s Health - p. 769 87. Chapter 68. Androgens - p. 769a 88. Chapter 69. Drugs for Male Sexual Dysfunction and Benign Prostatic Hyperplasia - p. 778 89. Unit XI: Antiinflammatory, Antiallergic, and Immunologic Drugs - p. 791 90. Chapter 70. Review of the Immune System - p. 791a 91. Chapter 71. Childhood Immunization - p. 802 92. Chapter 72. Immunosuppressants - p. 818 93. Chapter 73. Antihistamines - p. 828 94. Chapter 74. Cyclooxygenase Inhibitors: Nonsteroidal Antiinflammatory Drugs and Acetaminophen - p. 836 95. Chapter 75. Glucocorticoids in Nonendocrine Disorders - p. 853 96. Unit XII: Drugs for Bone and Joint Disorders - p. 863 97. Chapter 76. Drug Therapy for Rheumatoid Arthritis - p. 863a 98. Chapter 77. Drug Therapy for Gout - p. 879 99. Chapter 78. Drugs Affecting Calcium Levels and Bone Mineralization - p. 886 100. Unit XIII: Respiratory Tract Drugs - p. 911 101. Chapter 79. Drugs for Asthma and Chronic Obstructive Pulmonary Disease - p. 911a 102. Chapter 80. Drugs for Allergic Rhinitis, Cough, and Colds - p. 939 103. Unit XIV: Gastrointestinal Drugs - p. 947 104. Chapter 81. Drugs for Peptic Ulcer Disease - p. 947a 105. Chapter 82. Laxatives - p. 960 106. Chapter 83. Other Gastrointestinal Drugs - p. 969 107. Unit XV: Nutrition and Complementary Therapy - p. 983 108. Chapter 84. Vitamins - p. 983a 109. Chapter 85. Drugs for Weight Loss - p. 996 110. Chapter 86. Complementary and Alternative Therapy - p. 1005 111. Unit XVI: Drugs for Infectious Diseases - p. 1020 112. Chapter 87. Basic Principles of Antimicrobial Therapy - p. 1020a 113. Chapter 88. Drugs That Weaken the Bacterial Cell Wall I: Penicillins - p. 1034 114. Chapter 89. Drugs That Weaken the Bacterial Cell Wall II: Other Drugs - p. 1042 115. Chapter 90. Bacteriostatic Inhibitors of Protein Synthesis: Tetracyclines, Macrolides, and Others - p. 1053 116. Chapter 91. Aminoglycosides: Bactericidal Inhibitors of Protein Synthesis - p. 1062 117. Chapter 92. Sulfonamide Antibiotics and Trimethoprim - p. 1069 118. Chapter 93. Drug Therapy for Urinary Tract Infections - p. 1078 119. Chapter 94. Antimycobacterial Agents - p. 1083 120. Chapter 95. Miscellaneous Antibacterial Drugs - p. 1100 121. Chapter 96. Antifungal Agents - p. 1106 122. Chapter 97. Antiviral Agents I: Drugs for Non-HIV Viral Infections - p. 1117 123. Chapter 98. Antiviral Agents II: Drugs for HIV Infection and Related Opportunistic Infections - p. 1141 124. Chapter 99. Drug Therapy for Sexually Transmitted Infections - p. 1177 125. Chapter 100. Antiseptics and Disinfectants - p. 1186 126. Unit XVII: Drugs for Parasitic Diseases - p. 1193 127. Chapter 101. Anthelmintics - p. 1193a 128. Chapter 102. Antiprotozoal Drugs I: Antimalarial Agents - p. 1200 129. Chapter 103. Antiprotozoal Drugs II: Miscellaneous Agents - p. 1210 130. Chapter 104. Ectoparasiticides - p. 1215 131. Unit XVIII: Cancer Therapy - p. 1221 132. Chapter 105. Basic Principles of Cancer Therapy - p. 1221a 133. Chapter 106. Anticancer Drugs I: Cytotoxic Agents - p. 1235 134. Chapter 107. Anticancer Drugs II: Noncytotoxic Agents - p. 1256 135. Unit XIX: Drugs For Eyes, Ears, And Skin - p. 1278 136. Chapter 108. Drugs for Eye Conditions and Diseases - p. 1278a 137. Chapter 109. Drugs for Skin Conditions - p. 1291 138. Chapter 110. Drugs for Ear Conditions - p. 1314 139. Unit XX: Toxicology - p. 1321 140. Chapter 111. Management of Poisoning - p. 1321a 141. Chapter 112. Potential Weapons of Biologic, Radiologic, and Chemical Terrorism - p. 1326 142. Appendix A. Canadian Drug Information* - p. 1336 143. Appendix B. Prototype Drugs and Their Major Uses - p. 1340 144. Index - p. 1348 145. Special Interest Topics - p. IBC1
Trust Lehne’s to make pharmacology more approachable! Known for its clear explanations of drug prototypes and how they work, Lehne's Pharmacology for Nursing Care, 11th Edition provides a solid understanding of key drugs and their implications for nursing care. A perennial student favorite, this book simplifies complex pharmacology concepts, using large and small print to distinguish need-to-know drug content from the material that’s merely nice to know. It also includes in-depth coverage of physiology, pathophysiology and drug therapy. Written by noted nursing educators Jacqueline Rosenjack Burchum and Laura Rosenthal, this text helps you understand and apply pharmacology principles as opposed to simply memorizing drug facts.
1. Unit I: Introduction - p. 1 2. Chapter 1. Orientation to Pharmacology - p. 1a 3. Chapter 2. Application of Pharmacology in Nursing Practice - p. 5 4. Chapter 3. Drug Regulation, Development, Names, and Information - p. 14 5. Unit II: Basic Principles of Pharmacology - p. 24 6. Chapter 4. Pharmacokinetics - p. 24a 7. Chapter 5. Pharmacodynamics - p. 44 8. Chapter 6. Drug Interactions - p. 55 9. Chapter 7. Adverse Drug Reactions and Medication Errors - p. 63 10. Chapter 8. Individual Variation in Drug Responses - p. 74 11. Chapter 9. Genetic and Genomic Considerations - p. 79 12. Chapter 10. Introduction to Immunomodulators - p. 85 13. Unit III: Drug Therapy Across The Life Span - p. 90 14. Chapter 11. Drug Therapy During Pregnancy and Breast-Feeding - p. 90a 15. Chapter 12. Drug Therapy in Pediatric Patients - p. 98 16. Chapter 13. Drug Therapy in Older Adults - p. 102 17. Unit IV: Peripheral Nervous System Drugs - p. 108 18. Section 1: Introduction - p. 108a 19. Chapter 14. Basic Principles of Neuropharmacology - p. 108b 20. Chapter 15. Physiology of the Peripheral Nervous System - p. 113 21. Section 2: Cholinergic Drugs - p. 126 22. Chapter 16. Muscarinic Agonists - p. 126a 23. Chapter 17. Muscarinic Antagonists - p. 131 24. Chapter 18. Cholinesterase Inhibitors and Their Use in Myasthenia Gravis - p. 141 25. Chapter 19. Drugs That Block Nicotinic Cholinergic Transmission - p. 148 26. Section 3: Adrenergic Drugs - p. 157 27. Chapter 20. Adrenergic Agonists - p. 157a 28. Chapter 21. Adrenergic Antagonists - p. 170 29. Chapter 22. Indirect-Acting Antiadrenergic Agents - p. 183 30. Unit V: Central Nervous System Drugs - p. 188 31. Section 4: Introduction - p. 188a 32. Chapter 23. Introduction to Central Nervous System Pharmacology - p. 188b 33. Section 5: Drugs for Neurodegenerative Disorders - p. 191 34. Chapter 24. Drugs for Parkinson Disease - p. 191a 35. Chapter 25. Drugs for Alzheimer Disease - p. 209 36. Chapter 26. Drugs for Multiple Sclerosis - p. 216 37. Section 6: Neurologic Drugs - p. 234 38. Chapter 27. Drugs for Seizure Disorders - p. 234a 39. Chapter 28. Drugs for Muscle Spasm and Spasticity - p. 262 40. Section 7: Drugs for Pain - p. 271 41. Chapter 29. Local Anesthetics - p. 271a 42. Chapter 30. General Anesthetics - p. 277 43. Chapter 31. Opioid Analgesics, Opioid Antagonists, and Nonopioid Centrally Acting Analgesics - p. 286 44. Chapter 32. Pain Management in Patients With Cancer - p. 307 45. Chapter 33. Drugs for Headache - p. 323 46. Section 8: Psychotherapeutic Drugs - p. 334 47. Chapter 34. Antipsychotic Agents and Their Use in Schizophrenia - p. 334a 48. Chapter 35. Antidepressants - p. 351 49. Chapter 36. Drugs for Bipolar Disorder - p. 372 50. Chapter 37. Sedative-Hypnotic Drugs - p. 380 51. Chapter 38. Management of Anxiety Disorders - p. 395 52. Chapter 39. Central Nervous System Stimulants and Attention-Deficit/Hyperactivity Disorder - p. 402 53. Section 9: Substance Use Disorders - p. 412 54. Chapter 40. Substance Use Disorders I: Basic Considerations - p. 412a 55. Chapter 41. Substance Use Disorders II: Alcohol - p. 419 56. Chapter 42. Substance Use Disorders III: Nicotine - p. 430 57. Chapter 43. Substance Use Disorders IV: Major Drugs of Abuse Other Than Alcohol and Nicotine - p. 438 58. Unit VI: Drugs That Affect Fluid and Electrolyte Balance - p. 454 59. Chapter 44. Diuretics - p. 454a 60. Chapter 45. Agents Affecting the Volume and Ion Content of Body Fluids - p. 466 61. Unit VII: Drugs That Affect The Heart, Blood Vessels, and Blood - p. 471 62. Chapter 46. Review of Hemodynamics - p. 471a 63. Chapter 47. Drugs Acting on the Renin-Angiotensin-Aldosterone System - p. 477 64. Chapter 48. Calcium Channel Blockers - p. 492 65. Chapter 49. Vasodilators - p. 500 66. Chapter 50. Drugs for Hypertension - p. 505 67. Chapter 51. Drugs for Heart Failure - p. 523 68. Chapter 52. Antidysrhythmic Drugs - p. 540 69. Chapter 53. Drugs That Help Normalize Cholesterol and Triglyceride Levels - p. 559 70. Chapter 54. Drugs for Angina Pectoris - p. 581 71. Chapter 55. Anticoagulant, Antiplatelet, and Thrombolytic Drugs - p. 594 72. Chapter 56. Management of ST-Elevation Myocardial Infarction - p. 620 73. Chapter 57. Drugs for Hemophilia - p. 627 74. Chapter 58. Drugs for Deficiency Anemias - p. 635 75. Chapter 59. Hematopoietic Agents - p. 650 76. Unit VIII: Drugs for Endocrine Disorders - p. 660 77. Chapter 60. Drugs for Diabetes Mellitus - p. 660a 78. Chapter 61. Drugs for Thyroid Disorders - p. 694 79. Chapter 62. Drugs Related to Hypothalamic and Pituitary Function - p. 705 80. Chapter 63. Drugs for Disorders of the Adrenal Cortex - p. 713 81. Unit IX: Women’s Health - p. 720 82. Chapter 64. Estrogens and Progestins: Basic Pharmacology and Noncontraceptive Applications - p. 720a 83. Chapter 65. Birth Control - p. 734 84. Chapter 66. Drug Therapy for Infertility - p. 749 85. Chapter 67. Drugs That Affect Uterine Function - p. 757 86. Unit X: Men’s Health - p. 769 87. Chapter 68. Androgens - p. 769a 88. Chapter 69. Drugs for Male Sexual Dysfunction and Benign Prostatic Hyperplasia - p. 778 89. Unit XI: Antiinflammatory, Antiallergic, and Immunologic Drugs - p. 791 90. Chapter 70. Review of the Immune System - p. 791a 91. Chapter 71. Childhood Immunization - p. 802 92. Chapter 72. Immunosuppressants - p. 818 93. Chapter 73. Antihistamines - p. 828 94. Chapter 74. Cyclooxygenase Inhibitors: Nonsteroidal Antiinflammatory Drugs and Acetaminophen - p. 836 95. Chapter 75. Glucocorticoids in Nonendocrine Disorders - p. 853 96. Unit XII: Drugs for Bone and Joint Disorders - p. 863 97. Chapter 76. Drug Therapy for Rheumatoid Arthritis - p. 863a 98. Chapter 77. Drug Therapy for Gout - p. 879 99. Chapter 78. Drugs Affecting Calcium Levels and Bone Mineralization - p. 886 100. Unit XIII: Respiratory Tract Drugs - p. 911 101. Chapter 79. Drugs for Asthma and Chronic Obstructive Pulmonary Disease - p. 911a 102. Chapter 80. Drugs for Allergic Rhinitis, Cough, and Colds - p. 939 103. Unit XIV: Gastrointestinal Drugs - p. 947 104. Chapter 81. Drugs for Peptic Ulcer Disease - p. 947a 105. Chapter 82. Laxatives - p. 960 106. Chapter 83. Other Gastrointestinal Drugs - p. 969 107. Unit XV: Nutrition and Complementary Therapy - p. 983 108. Chapter 84. Vitamins - p. 983a 109. Chapter 85. Drugs for Weight Loss - p. 996 110. Chapter 86. Complementary and Alternative Therapy - p. 1005 111. Unit XVI: Drugs for Infectious Diseases - p. 1020 112. Chapter 87. Basic Principles of Antimicrobial Therapy - p. 1020a 113. Chapter 88. Drugs That Weaken the Bacterial Cell Wall I: Penicillins - p. 1034 114. Chapter 89. Drugs That Weaken the Bacterial Cell Wall II: Other Drugs - p. 1042 115. Chapter 90. Bacteriostatic Inhibitors of Protein Synthesis: Tetracyclines, Macrolides, and Others - p. 1053 116. Chapter 91. Aminoglycosides: Bactericidal Inhibitors of Protein Synthesis - p. 1062 117. Chapter 92. Sulfonamide Antibiotics and Trimethoprim - p. 1069 118. Chapter 93. Drug Therapy for Urinary Tract Infections - p. 1078 119. Chapter 94. Antimycobacterial Agents - p. 1083 120. Chapter 95. Miscellaneous Antibacterial Drugs - p. 1100 121. Chapter 96. Antifungal Agents - p. 1106 122. Chapter 97. Antiviral Agents I: Drugs for Non-HIV Viral Infections - p. 1117 123. Chapter 98. Antiviral Agents II: Drugs for HIV Infection and Related Opportunistic Infections - p. 1141 124. Chapter 99. Drug Therapy for Sexually Transmitted Infections - p. 1177 125. Chapter 100. Antiseptics and Disinfectants - p. 1186 126. Unit XVII: Drugs for Parasitic Diseases - p. 1193 127. Chapter 101. Anthelmintics - p. 1193a 128. Chapter 102. Antiprotozoal Drugs I: Antimalarial Agents - p. 1200 129. Chapter 103. Antiprotozoal Drugs II: Miscellaneous Agents - p. 1210 130. Chapter 104. Ectoparasiticides - p. 1215 131. Unit XVIII: Cancer Therapy - p. 1221 132. Chapter 105. Basic Principles of Cancer Therapy - p. 1221a 133. Chapter 106. Anticancer Drugs I: Cytotoxic Agents - p. 1235 134. Chapter 107. Anticancer Drugs II: Noncytotoxic Agents - p. 1256 135. Unit XIX: Drugs For Eyes, Ears, And Skin - p. 1278 136. Chapter 108. Drugs for Eye Conditions and Diseases - p. 1278a 137. Chapter 109. Drugs for Skin Conditions - p. 1291 138. Chapter 110. Drugs for Ear Conditions - p. 1314 139. Unit XX: Toxicology - p. 1321 140. Chapter 111. Management of Poisoning - p. 1321a 141. Chapter 112. Potential Weapons of Biologic, Radiologic, and Chemical Terrorism - p. 1326 142. Appendix A. Canadian Drug Information* - p. 1336 143. Appendix B. Prototype Drugs and Their Major Uses - p. 1340 144. Index - p. 1348 145. Special Interest Topics - p. IBC1
