Ligands for Targeted Drug Delivery: Basic Fundamentals and Applications is a comprehensive reference focused on the many ways drug carriers can be functionalized to target specific organs, tissues, cells, and sub-cellular compartments. Chapters cover the basic concepts of targeted drug delivery, describing multiple levels of targets and challenges, along with approaches for target-specific drug delivery and a thorough overview of the challenges in design and application of ligands. Following sections discuss nanoparticles and the main ligand classes with their respective applications. The final chapters discuss future prospects of the technology and clinical aspects of ligand modified drug delivery systems.
This is a key reference to drug delivery researchers dealing with the application of ligands to overcome challenges in delivering their active principles to the target structure. Biomedical engineers, materials scientists, and chemists can also benefit from the through description of ligand classes and their potential to improve drug delivery efficiency.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. List of contributors - p. xvii 7. About the editors - p. xxiii 8. Chapter 1. Basic concepts and levels of drug targeting - p. 1 9. Chapter 2. Ligand-based approaches for target-specific drug delivery - p. 53 10. Chapter 3. Challenges in the design of ligand-targeted drug delivery systems - p. 101 11. Chapter 4. Ligand conjugation strategies - p. 159 12. Chapter 5. Aptamers: applications for targeted drug delivery - p. 191 13. Chapter 6. Sugar as a ligand and applications in drug delivery - p. 227 14. Chapter 7. Proteins, peptides and its derivatives as ligand and applications in drug delivery - p. 257 15. Chapter 8. Biological ligands and applications in drug delivery - p. 285 16. Chapter 9. Polymers as ligand and applications in drug delivery - p. 313 17. Chapter 10. Approaches for tight junction opening - p. 339 18. Chapter 11. Future prospects of targeted drug delivery - p. 377 19. Chapter 12. Clinical aspects of ligand-modified drug delivery systems - p. 403 20. Index - p. 419
Ligands for Targeted Drug Delivery: Basic Fundamentals and Applications is a comprehensive reference focused on the many ways drug carriers can be functionalized to target specific organs, tissues, cells, and sub-cellular compartments. Chapters cover the basic concepts of targeted drug delivery, describing multiple levels of targets and challenges, along with approaches for target-specific drug delivery and a thorough overview of the challenges in design and application of ligands. Following sections discuss nanoparticles and the main ligand classes with their respective applications. The final chapters discuss future prospects of the technology and clinical aspects of ligand modified drug delivery systems.
This is a key reference to drug delivery researchers dealing with the application of ligands to overcome challenges in delivering their active principles to the target structure. Biomedical engineers, materials scientists, and chemists can also benefit from the through description of ligand classes and their potential to improve drug delivery efficiency.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. List of contributors - p. xvii 7. About the editors - p. xxiii 8. Chapter 1. Basic concepts and levels of drug targeting - p. 1 9. Chapter 2. Ligand-based approaches for target-specific drug delivery - p. 53 10. Chapter 3. Challenges in the design of ligand-targeted drug delivery systems - p. 101 11. Chapter 4. Ligand conjugation strategies - p. 159 12. Chapter 5. Aptamers: applications for targeted drug delivery - p. 191 13. Chapter 6. Sugar as a ligand and applications in drug delivery - p. 227 14. Chapter 7. Proteins, peptides and its derivatives as ligand and applications in drug delivery - p. 257 15. Chapter 8. Biological ligands and applications in drug delivery - p. 285 16. Chapter 9. Polymers as ligand and applications in drug delivery - p. 313 17. Chapter 10. Approaches for tight junction opening - p. 339 18. Chapter 11. Future prospects of targeted drug delivery - p. 377 19. Chapter 12. Clinical aspects of ligand-modified drug delivery systems - p. 403 20. Index - p. 419
