A number of areas within liver transplant continue to evolve as the field matures. The advent of increasingly effective therapy for HCV will dramatically reduce the burden of recurrent disease within the next few years. HCC has become a well established indication for transplant with an increasing emphasis on adjuvant therapies to reduce the risk of tumor recurrence and potentially expand the acceptable limits of tumor burden amenable to liver transplant. Renal dysfunction is a frequent complication of decompensated liver disease and an important predictor of diminished post-transplant survival. Newer approached to therapy including terlipressin will reduce the impact of renal dysfunction in liver transplant candidates and potentially reduce the need for combined liver/kidney transplant. Increasing attention is being paid to role of comorbidities such as diabetes and hypertension on long-term recipient outcomes. Retransplantation remains a challenge with a variety of models available to predict outcomes. Cardiac disease pretransplant is an area of active investigation with newer entities such as cirrhotic cardiomyopathy a growing concern. These are some of many evolving issues in liver transplant which will be addressed to update our readers and which in turn will enhance the care of patients with liver disease.
1. Cover image - p. 1 2. Title page - p. 2 3. Table of Contents - p. 3 4. Contributors - p. 4 5. Contents - p. 5 6. Forthcoming Issues - p. 7 7. Liver Transplantation: Update of Concepts and Practice - p. 8 8. Evolving Trends in Liver Transplantation - p. 9 9. Cardiac and Pulmonary Issues in LT Assessment Candidates - p. 14 10. Renal Dysfunction in End-Stage Liver Disease and Post–Liver Transplant - p. 20 11. Acute-On-Chronic Liver Failure - p. 31 12. Hepatitis Viruses and Liver Transplantation - p. 39 13. Liver Transplant for Hepatocellular Cancer - p. 53 14. The Adolescent Liver Transplant Patient - p. 58 15. Expanded Criteria Donors - p. 66 16. Challenges in Living Donor Liver Transplantation - p. 76 17. Multivisceral Transplantation - p. 83 18. Recurrence of Nonviral Liver Diseases After Liver Transplantation - p. 90 19. Immunosuppression - p. 95 20. Improving Long-Term Outcomes After Liver Transplantation - p. 108 21. Hepatic Retransplant - p. 116 22. Index - p. 128
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A number of areas within liver transplant continue to evolve as the field matures. The advent of increasingly effective therapy for HCV will dramatically reduce the burden of recurrent disease within the next few years. HCC has become a well established indication for transplant with an increasing emphasis on adjuvant therapies to reduce the risk of tumor recurrence and potentially expand the acceptable limits of tumor burden amenable to liver transplant. Renal dysfunction is a frequent complication of decompensated liver disease and an important predictor of diminished post-transplant survival. Newer approached to therapy including terlipressin will reduce the impact of renal dysfunction in liver transplant candidates and potentially reduce the need for combined liver/kidney transplant. Increasing attention is being paid to role of comorbidities such as diabetes and hypertension on long-term recipient outcomes. Retransplantation remains a challenge with a variety of models available to predict outcomes. Cardiac disease pretransplant is an area of active investigation with newer entities such as cirrhotic cardiomyopathy a growing concern. These are some of many evolving issues in liver transplant which will be addressed to update our readers and which in turn will enhance the care of patients with liver disease.
1. Cover image - p. 1 2. Title page - p. 2 3. Table of Contents - p. 3 4. Contributors - p. 4 5. Contents - p. 5 6. Forthcoming Issues - p. 7 7. Liver Transplantation: Update of Concepts and Practice - p. 8 8. Evolving Trends in Liver Transplantation - p. 9 9. Cardiac and Pulmonary Issues in LT Assessment Candidates - p. 14 10. Renal Dysfunction in End-Stage Liver Disease and Post–Liver Transplant - p. 20 11. Acute-On-Chronic Liver Failure - p. 31 12. Hepatitis Viruses and Liver Transplantation - p. 39 13. Liver Transplant for Hepatocellular Cancer - p. 53 14. The Adolescent Liver Transplant Patient - p. 58 15. Expanded Criteria Donors - p. 66 16. Challenges in Living Donor Liver Transplantation - p. 76 17. Multivisceral Transplantation - p. 83 18. Recurrence of Nonviral Liver Diseases After Liver Transplantation - p. 90 19. Immunosuppression - p. 95 20. Improving Long-Term Outcomes After Liver Transplantation - p. 108 21. Hepatic Retransplant - p. 116 22. Index - p. 128
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