**Selected for Doody’s Core Titles® 2024 in Clinical Genetics**
Medical Epigenetics, Second Edition provides a comprehensive analysis of epigenetics in health management, across a broad spectrum of disease categories and specialties, and with a focus on human systems, epigenetic diseases that affect these systems, and evolving modes of epigenetic-based treatment. Here, more than 40 leading researchers examine how each human system is affected by epigenetic maladies, offering an all-in-one resource on medical epigenetics not only for those directly involved with health care, but investigators in life sciences, biotech companies, graduate students, and others who are interested in applied aspects of epigenetics. Incorporating both diagnostic and prognostic epigenetic approaches, this volume also fully supports the application of epigenetics in precision medicine.
This second edition of Medical Epigenetics, a volume in the Translational Epigenetics series, has been fully revised to address recent advances in disease epigenetics and role of epigenetics in precision medicine, with all-new chapters on skin cancer epigenetics, network analysis in medical epigenetics, machine learning in epigenetic diseases, and clinical trials of epigenetics drugs.
1. Medical Epigenetics - p. Page i 2. Cover - p. Page i 3. Front Matter - p. Page i 4. Table of Contents - p. Page iv 5. Copyright - p. Page v 6. Contributors - p. Page v 7. Preface - p. Page ix 8. List of Illustrations - p. Page x 9. List of Tables - p. Page xi 10. Chapter 1 : Advances in medical epigenetics - p. Page xi 11. Chapter 2 : Environmental epigenetic epidemiology - p. Page 8 12. Chapter 3 : Lifestyle and preventive medical epigenetics - p. Page 26 13. Chapter 4 : Environmental medical epigenetics: A review of epigenetically induced medical risks generated from exposures in our air, food, and personal products - p. Page 43 14. Chapter 5 : Behavioral medical epigenetics - p. Page 73 15. Chapter 6 : Medical epigenetics and twins - p. Page 96 16. Chapter 7 : Epigenetic biomarkers of disease - p. Page 112 17. Chapter 8 : Prognostic epigenetics - p. Page 136 18. Chapter 9 : Autoimmune disease and epigenetics - p. Page 162 19. Chapter 10 : Epigenetics of pulmonary diseases - p. Page 178 20. Chapter 11 : Cardiovascular disorders and epigenetics - p. Page 194 21. Chapter 12 : Epigenomics of intestinal disease - p. Page 207 22. Chapter 13 : Epigenetics of skin disorders - p. Page 226 23. Chapter 14 : Epigenetics in bone and joint disorders - p. Page 245 24. Chapter 15 : Epigenetics of muscle disorders - p. Page 271 25. Chapter 16 : Reproductive disease epigenetics - p. Page 298 26. Chapter 17 : Epigenetics in ocular medicine - p. Page 334 27. Chapter 18 : Pediatric diseases and epigenetics - p. Page 363 28. Chapter 19 : Epigenetics of infectious diseases - p. Page 397 29. Chapter 20 : Clinical utility of solid tumor epigenetics - p. Page 419 30. Chapter 21 : Epigenetics in acute myeloid leukemia - p. Page 440 31. Chapter 22 : Epigenetic regulation in cancer metastasis - p. Page 461 32. Chapter 23 : Epigenetics in exercise science and sports medicine - p. Page 483 33. Chapter 24 : Machine learning in epigenetic diseases - p. Page 504 34. Chapter 25 : Epigenetics in toxicology and drug development - p. Page 524 35. Chapter 26 : Pharmacoepigenomics in neurodegenerative diseases - p. Page 553 36. Chapter 27 : Therapeutics and DNA methylation inhibitors - p. Page 576 37. Chapter 28 : Histone deacetylase inhibitors in medical therapeutics - p. Page 593 38. Chapter 29 : +Sirtuins as NAD - p. Page 621 39. Chapter 30 : Experimental approaches toward histone acetyltransferase modulators as therapeutics - p. Page 656 40. Chapter 31 : Histone methylation modifiers in medical therapeutics - p. Page 684 41. Chapter 32 : Modulation of noncoding RNAs (ncRNAs) and their potential role as therapeutics - p. Page 712 42. Chapter 33 : Nutrients and phytonutrients as promising epigenetic nutraceuticals - p. Page 732 43. Chapter 34 : Epigenetics of pain management - p. Page 796 44. Chapter 35 : Precision medical epigenetics - p. Page 831 45. Chapter 36 : Epigenetics and regenerative medicine - p. Page 849 46. Chapter 37 : Stem cell epigenetics in medical therapy - p. Page 866 47. Chapter 38 : The clinical landscape of HDAC inhibitors - p. Page 881 48. Chapter 39 : Epigenetics: Future prospective in human disorders and therapeutics - p. Page 896 49. Chapter 40 : Prospective advances in medical epigenetics - p. Page 914 50. Index - p. Page 932
**Selected for Doody’s Core Titles® 2024 in Clinical Genetics**
Medical Epigenetics, Second Edition provides a comprehensive analysis of epigenetics in health management, across a broad spectrum of disease categories and specialties, and with a focus on human systems, epigenetic diseases that affect these systems, and evolving modes of epigenetic-based treatment. Here, more than 40 leading researchers examine how each human system is affected by epigenetic maladies, offering an all-in-one resource on medical epigenetics not only for those directly involved with health care, but investigators in life sciences, biotech companies, graduate students, and others who are interested in applied aspects of epigenetics. Incorporating both diagnostic and prognostic epigenetic approaches, this volume also fully supports the application of epigenetics in precision medicine.
This second edition of Medical Epigenetics, a volume in the Translational Epigenetics series, has been fully revised to address recent advances in disease epigenetics and role of epigenetics in precision medicine, with all-new chapters on skin cancer epigenetics, network analysis in medical epigenetics, machine learning in epigenetic diseases, and clinical trials of epigenetics drugs.
1. Medical Epigenetics - p. Page i 2. Cover - p. Page i 3. Front Matter - p. Page i 4. Table of Contents - p. Page iv 5. Copyright - p. Page v 6. Contributors - p. Page v 7. Preface - p. Page ix 8. List of Illustrations - p. Page x 9. List of Tables - p. Page xi 10. Chapter 1 : Advances in medical epigenetics - p. Page xi 11. Chapter 2 : Environmental epigenetic epidemiology - p. Page 8 12. Chapter 3 : Lifestyle and preventive medical epigenetics - p. Page 26 13. Chapter 4 : Environmental medical epigenetics: A review of epigenetically induced medical risks generated from exposures in our air, food, and personal products - p. Page 43 14. Chapter 5 : Behavioral medical epigenetics - p. Page 73 15. Chapter 6 : Medical epigenetics and twins - p. Page 96 16. Chapter 7 : Epigenetic biomarkers of disease - p. Page 112 17. Chapter 8 : Prognostic epigenetics - p. Page 136 18. Chapter 9 : Autoimmune disease and epigenetics - p. Page 162 19. Chapter 10 : Epigenetics of pulmonary diseases - p. Page 178 20. Chapter 11 : Cardiovascular disorders and epigenetics - p. Page 194 21. Chapter 12 : Epigenomics of intestinal disease - p. Page 207 22. Chapter 13 : Epigenetics of skin disorders - p. Page 226 23. Chapter 14 : Epigenetics in bone and joint disorders - p. Page 245 24. Chapter 15 : Epigenetics of muscle disorders - p. Page 271 25. Chapter 16 : Reproductive disease epigenetics - p. Page 298 26. Chapter 17 : Epigenetics in ocular medicine - p. Page 334 27. Chapter 18 : Pediatric diseases and epigenetics - p. Page 363 28. Chapter 19 : Epigenetics of infectious diseases - p. Page 397 29. Chapter 20 : Clinical utility of solid tumor epigenetics - p. Page 419 30. Chapter 21 : Epigenetics in acute myeloid leukemia - p. Page 440 31. Chapter 22 : Epigenetic regulation in cancer metastasis - p. Page 461 32. Chapter 23 : Epigenetics in exercise science and sports medicine - p. Page 483 33. Chapter 24 : Machine learning in epigenetic diseases - p. Page 504 34. Chapter 25 : Epigenetics in toxicology and drug development - p. Page 524 35. Chapter 26 : Pharmacoepigenomics in neurodegenerative diseases - p. Page 553 36. Chapter 27 : Therapeutics and DNA methylation inhibitors - p. Page 576 37. Chapter 28 : Histone deacetylase inhibitors in medical therapeutics - p. Page 593 38. Chapter 29 : +Sirtuins as NAD - p. Page 621 39. Chapter 30 : Experimental approaches toward histone acetyltransferase modulators as therapeutics - p. Page 656 40. Chapter 31 : Histone methylation modifiers in medical therapeutics - p. Page 684 41. Chapter 32 : Modulation of noncoding RNAs (ncRNAs) and their potential role as therapeutics - p. Page 712 42. Chapter 33 : Nutrients and phytonutrients as promising epigenetic nutraceuticals - p. Page 732 43. Chapter 34 : Epigenetics of pain management - p. Page 796 44. Chapter 35 : Precision medical epigenetics - p. Page 831 45. Chapter 36 : Epigenetics and regenerative medicine - p. Page 849 46. Chapter 37 : Stem cell epigenetics in medical therapy - p. Page 866 47. Chapter 38 : The clinical landscape of HDAC inhibitors - p. Page 881 48. Chapter 39 : Epigenetics: Future prospective in human disorders and therapeutics - p. Page 896 49. Chapter 40 : Prospective advances in medical epigenetics - p. Page 914 50. Index - p. Page 932