Known for its up-to-date coverage of both basic science and clinical application, Medical Genetics and Genomics, 7th Edition, has been fully revised to reflect recent advances in the genetics of common diseases, as well as current progress in genetic testing and gene therapy. This accessible, practical text integrates key concepts with clinical practice, highlighted by numerous illustrations, tables, concept summaries, and more—all designed to enhance effective learning and retention of complex material.
1. Cover image - p. c 2. Title page - p. iii 3. Copyright - p. iv 4. Dedication - p. v 5. Preface - p. vi 6. Acknowledgments - p. vii 7. Contents - p. viii 8. 1 Background and History - p. 1 9. 2 Basic Cell Biology - p. 5 10. 3 Genetic Variation: - p. 25 11. 4 Autosomal Dominant and Recessive Inheritance - p. 53 12. 5 Sex-Linked and Nontraditional Modes of Inheritance - p. 71 13. 6 Clinical Cytogenetics - p. 94 14. 7 Biochemical Genetics: - p. 122 15. 8 Disease-Gene Identification - p. 142 16. 9 Immunogenetics - p. 165 17. 10 Genetic Basis of Development - p. 180 18. 11 Cancer Genetics - p. 200 19. 12 Multifactorial Inheritance and Common Diseases - p. 220 20. 13 Genetic Testing and Gene Therapy - p. 244 21. 14 Genetics and Precision Medicine - p. 270 22. 15 Clinical Genetics and Genetic Counseling - p. 278 23. Glossary - p. 303 24. Answers to Study Questions - p. 319 25. Index - p. 329
Known for its up-to-date coverage of both basic science and clinical application, Medical Genetics and Genomics, 7th Edition, has been fully revised to reflect recent advances in the genetics of common diseases, as well as current progress in genetic testing and gene therapy. This accessible, practical text integrates key concepts with clinical practice, highlighted by numerous illustrations, tables, concept summaries, and more—all designed to enhance effective learning and retention of complex material.
1. Cover image - p. c 2. Title page - p. iii 3. Copyright - p. iv 4. Dedication - p. v 5. Preface - p. vi 6. Acknowledgments - p. vii 7. Contents - p. viii 8. 1 Background and History - p. 1 9. 2 Basic Cell Biology - p. 5 10. 3 Genetic Variation: - p. 25 11. 4 Autosomal Dominant and Recessive Inheritance - p. 53 12. 5 Sex-Linked and Nontraditional Modes of Inheritance - p. 71 13. 6 Clinical Cytogenetics - p. 94 14. 7 Biochemical Genetics: - p. 122 15. 8 Disease-Gene Identification - p. 142 16. 9 Immunogenetics - p. 165 17. 10 Genetic Basis of Development - p. 180 18. 11 Cancer Genetics - p. 200 19. 12 Multifactorial Inheritance and Common Diseases - p. 220 20. 13 Genetic Testing and Gene Therapy - p. 244 21. 14 Genetics and Precision Medicine - p. 270 22. 15 Clinical Genetics and Genetic Counseling - p. 278 23. Glossary - p. 303 24. Answers to Study Questions - p. 319 25. Index - p. 329
