Medications for Older Persons: Recommendations, Harms, Evidence provides a comprehensive resource detailing the benefits of medications for older individuals. It also addresses the potential harms associated with the prescription of potentially inappropriate medications or omissions in prescribing and examines how many adverse events, rehospitalizations, and deaths can be attributed to these medications. The book opens with a summary of medications that most benefit older patients, followed by the impact of older persons’ alcohol consumption, self-medication, and medication list accuracy and how these factors correlate to health outcomes.
The remainder of the book is devoted to the assessment of medication groups focusing on Numbers Needed to Treat, Numbers Needed to Harm, and characteristics and numbers of adverse events. Medication groups covered include cardiovascular, central nervous system, renal, gastrointestinal, musculoskeletal, respiratory, endocrine, pain, and fall prevention.
1. Introduction - p. xxiii 2. 1. STOPP criteria and Beers' criteria for potentially inappropriate medications (PIMs), and START criteria for potential prescribing omissions (PPOs) - p. 1 3. 2. “Potentially inappropriate medications” and “potential prescribing omissions” of patients ≥65 hospitalized in Calgary, Canada, 2013–21, most strongly associated with readmissions and mortality, and costs compared to New Zealand, the lowest-cost OECD country - p. 17 4. 3. How STOPP/START and American Geriatrics Society criteria medications are metabolized by the P450 enzyme system and medication metabolism varies by genome - p. 31 5. 4. Methods to identify adverse drug interactions and events - p. 49 6. 5. Alcohol–medication interactions in older people - p. 71 7. 6. Improving medication list accuracy across transitions of care: Impacts on PIMs, PPOs, and adverse events in older adults - p. 89 8. 7. Hypertensive medications for older persons - p. 105 9. 8. Pharmacologic management of diabetes in older adults - p. 123 10. 9. Medications for anti-coagulation in stroke prevention - p. 141 11. 10. Medications for anxiety - p. 155 12. 11. Medications for insomnia - p. 177 13. 12. Neuroleptic/antipsychotic medications - p. 221 14. 13. Prevention and treatment of delirium in older persons - p. 231 15. 14. Efficacy and harms of nonsteroidal antiinflammatory drugs (NSAIDs) and opioids for musculoskeletal pain in older persons - p. 249 16. 15. Medications for osteoporosis - p. 277 17. 16. Prescribing to prevent falls - p. 307 18. Index - p. 325
Medications for Older Persons: Recommendations, Harms, Evidence provides a comprehensive resource detailing the benefits of medications for older individuals. It also addresses the potential harms associated with the prescription of potentially inappropriate medications or omissions in prescribing and examines how many adverse events, rehospitalizations, and deaths can be attributed to these medications. The book opens with a summary of medications that most benefit older patients, followed by the impact of older persons’ alcohol consumption, self-medication, and medication list accuracy and how these factors correlate to health outcomes.
The remainder of the book is devoted to the assessment of medication groups focusing on Numbers Needed to Treat, Numbers Needed to Harm, and characteristics and numbers of adverse events. Medication groups covered include cardiovascular, central nervous system, renal, gastrointestinal, musculoskeletal, respiratory, endocrine, pain, and fall prevention.
1. Introduction - p. xxiii 2. 1. STOPP criteria and Beers' criteria for potentially inappropriate medications (PIMs), and START criteria for potential prescribing omissions (PPOs) - p. 1 3. 2. “Potentially inappropriate medications” and “potential prescribing omissions” of patients ≥65 hospitalized in Calgary, Canada, 2013–21, most strongly associated with readmissions and mortality, and costs compared to New Zealand, the lowest-cost OECD country - p. 17 4. 3. How STOPP/START and American Geriatrics Society criteria medications are metabolized by the P450 enzyme system and medication metabolism varies by genome - p. 31 5. 4. Methods to identify adverse drug interactions and events - p. 49 6. 5. Alcohol–medication interactions in older people - p. 71 7. 6. Improving medication list accuracy across transitions of care: Impacts on PIMs, PPOs, and adverse events in older adults - p. 89 8. 7. Hypertensive medications for older persons - p. 105 9. 8. Pharmacologic management of diabetes in older adults - p. 123 10. 9. Medications for anti-coagulation in stroke prevention - p. 141 11. 10. Medications for anxiety - p. 155 12. 11. Medications for insomnia - p. 177 13. 12. Neuroleptic/antipsychotic medications - p. 221 14. 13. Prevention and treatment of delirium in older persons - p. 231 15. 14. Efficacy and harms of nonsteroidal antiinflammatory drugs (NSAIDs) and opioids for musculoskeletal pain in older persons - p. 249 16. 15. Medications for osteoporosis - p. 277 17. 16. Prescribing to prevent falls - p. 307 18. Index - p. 325
