This issue of Neurosurgery Clinics, guest edited by Drs. Edjah Nduom and Jeff Olson, will focus on Metastases to the Central Nervous System. This issue is one of four selected each year by our series consulting editors, Dr. Russell R. Lonser and Dr. Daniel K. Resnick. Topics discussed in this issue will include: Epidemiology of metastatic CNS disease, Initial approach to the patient with a newly diagnosed solitary brain metastasis, Initial approach to the patient with multiple newly diagnosed brain metastases, When to consider a stereotactic biopsy for brain metastases, Techniques for open surgical resection of cerebral metastases, Laser ablation for cerebral metastases, Histopathological features and laboratory markers of common brain metastases, Recurrence vs radiation necrosis – evaluation and treatment, Anti-epileptic drugs for the management of cerebral metastases, Chemotherapy for the management of cerebral metastases, Approach to the management of metastatic leptomeningeal disease, Immune therapy for CNS metastases, Novel therapeutic targets for the treatment of cerebral metastases, Skull base metastases – diagnosis and management, and more.
1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. Neurosurgery Clinics of North America - p. xii 7. Preface - p. xiii 8. Epidemiology of Brain Metastases - p. 481 9. Initial Approach to Patients with a Newly Diagnosed Solitary Brain Metastasis - p. 489 10. Initial Approach to the Patient with Multiple Newly Diagnosed Brain Metastases - p. 505 11. The Role of Stereotactic Biopsy in Brain Metastases - p. 515 12. Techniques for Open Surgical Resection of Brain Metastases - p. 527 13. Laser Ablation for Cerebral Metastases - p. 537 14. Pathological Features of Brain Metastases - p. 549 15. Whole-Brain Radiation Therapy Versus Stereotactic Radiosurgery for Cerebral Metastases - p. 565 16. Brain Metastasis Recurrence Versus Radiation Necrosis: Evaluation and Treatment - p. 575 17. Antiepileptic Drugs in the Management of Cerebral Metastases - p. 589 18. Chemotherapy for the Management of Cerebral Metastases - p. 603 19. Leptomeningeal Carcinomatosis: Molecular Landscape, Current Management, and Emerging Therapies - p. 613 20. Immune Therapy for Central Nervous System Metastasis - p. 627 21. Targeting the Tumor Microenvironment in Brain Metastasis - p. 641 22. Sellar Metastases: Diagnosis and Management - p. 651 23. Management of Skull Base Metastases - p. 659
This issue of Neurosurgery Clinics, guest edited by Drs. Edjah Nduom and Jeff Olson, will focus on Metastases to the Central Nervous System. This issue is one of four selected each year by our series consulting editors, Dr. Russell R. Lonser and Dr. Daniel K. Resnick. Topics discussed in this issue will include: Epidemiology of metastatic CNS disease, Initial approach to the patient with a newly diagnosed solitary brain metastasis, Initial approach to the patient with multiple newly diagnosed brain metastases, When to consider a stereotactic biopsy for brain metastases, Techniques for open surgical resection of cerebral metastases, Laser ablation for cerebral metastases, Histopathological features and laboratory markers of common brain metastases, Recurrence vs radiation necrosis – evaluation and treatment, Anti-epileptic drugs for the management of cerebral metastases, Chemotherapy for the management of cerebral metastases, Approach to the management of metastatic leptomeningeal disease, Immune therapy for CNS metastases, Novel therapeutic targets for the treatment of cerebral metastases, Skull base metastases – diagnosis and management, and more.
1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. Neurosurgery Clinics of North America - p. xii 7. Preface - p. xiii 8. Epidemiology of Brain Metastases - p. 481 9. Initial Approach to Patients with a Newly Diagnosed Solitary Brain Metastasis - p. 489 10. Initial Approach to the Patient with Multiple Newly Diagnosed Brain Metastases - p. 505 11. The Role of Stereotactic Biopsy in Brain Metastases - p. 515 12. Techniques for Open Surgical Resection of Brain Metastases - p. 527 13. Laser Ablation for Cerebral Metastases - p. 537 14. Pathological Features of Brain Metastases - p. 549 15. Whole-Brain Radiation Therapy Versus Stereotactic Radiosurgery for Cerebral Metastases - p. 565 16. Brain Metastasis Recurrence Versus Radiation Necrosis: Evaluation and Treatment - p. 575 17. Antiepileptic Drugs in the Management of Cerebral Metastases - p. 589 18. Chemotherapy for the Management of Cerebral Metastases - p. 603 19. Leptomeningeal Carcinomatosis: Molecular Landscape, Current Management, and Emerging Therapies - p. 613 20. Immune Therapy for Central Nervous System Metastasis - p. 627 21. Targeting the Tumor Microenvironment in Brain Metastasis - p. 641 22. Sellar Metastases: Diagnosis and Management - p. 651 23. Management of Skull Base Metastases - p. 659
