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Mitochondrial Physiology and Vegetal Molecules: Therapeutic potential of natural compounds on mitochondrial health provides a comprehensive overview of mitochondrial physiology throughout the human life span, as well as the effect of molecules of vegetal origin on mitochondrial health. The editor has lined up a team of worldwide experts to cover the most exciting and high-impact advancements of research in this area.

This book is structured into two parts that provide a balance of both foundational and applied content. Part I provides an overview of mitochondrial physiology including its structure, dynamics, biogenesis, membranes, DNA transcription, and translation in the mitochondria. Part I also covers other themes such as apoptosis. Part II then covers the effect of specific vegetable-derived molecules on mitochondrial health, including anthocyanins, caffeine, cannabinoids, carnosic and rosmarinic acids, citrus flavonoids, polyphenols, pterostilbene, resveratrol, and sulforaphane, among others.

Mitochondrial Physiology and Vegetal Molecules: Therapeutic potential of natural compounds on mitochondrial health is a complete resource for researchers in this exciting field. Its comprehensive coverage makes it particularly interesting to bioscience researchers willing to understand the foundations of mitochondrial physiology throughout the human life span. Clinician researchers, MDs, nutritionists, pharmacologists, and sports scientists may be attracted to the detailed information on the health effects of vegetal origin molecules on the organelle.

  • Contains detailed information on plant products and their effect on mitochondria
  • Proposes therapies and reviews mechanisms of absorption at the cellular level
  • Discusses the limited bioavailability of plant molecules/compounds in the human organism
  • Includes coverage of specific conditions such as Sports and affective disorders, among others
  • Presents the protective effects of plant products in mitochondrial health through all stages of life

1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iii 6. Dedication - p. iii 7. Contributors - p. xxv 8. About the editor - p. xxxiii 9. Preface - p. xxxvii 10. Acknowledgments - p. xli 11. Part I: Overview of mitochondrial physiology - p. xli 12. Chapter 1. Mitochondria: Ultrastructure, dynamics, biogenesis, and main functions - p. 3 13. Chapter 2. Mitochondrial biogenesis and mitophagy - p. 35 14. Chapter 3. DNA transcription and translation in mitochondria - p. 91 15. Chapter 4. Mitochondrial redox biology: Reactive species production and antioxidant defenses - p. 105 16. Chapter 5. Mitochondria and apoptosis - p. 127 17. Chapter 6. Mitochondria-associated membranes in the maintenance of cell homeostasis - p. 151 18. Part II: The effects of plant molecules on the mitochondria in health and disease - p. 169 19. Chapter 7. Biopharmaceutical properties of natural products - p. 173 20. Chapter 8. Carnosic acid and brain mitochondria - p. 191 21. Chapter 9. Rosmarinic acid and mitochondria - p. 215 22. Chapter 10. Sulforaphane and mitochondria - p. 233 23. Chapter 11. Cannabinoids and mitochondria - p. 247 24. Chapter 12. Anthocyanins, effects in mitochondria and metabolism - p. 267 25. Chapter 13. Preclinical evidence of the therapeutic role of pterostilbene: Focus on the mitochondria - p. 301 26. Chapter 14. Polyphenols attenuate mitochondrial dysfunction induced by amyloid peptides - p. 324 27. Chapter 15. Plant molecules to treat eye mitochondria - p. 339 28. Chapter 16. Mitochondria as a target for monoterpenes - p. 359 29. Baccharis trimera phytochemicals and the mitochondria - p. 379 30. Chapter 18. Citrus flavonoids and the mitochondria - p. 395 31. Chapter 19. Caffeine and mitochondria with a focus on the central nervous system - p. 413 32. Chapter 20. Curcumin and mitochondria - p. 439 33. Chapter 21. Catechins, neuroprotection, and brain mitochondria - p. 455 34. Chapter 22. The effects of catechins on the cardiac mitochondria - p. 471 35. Chapter 23. Possible roles of garlic and its bioactive components on mitochondrial function in physiological and pathological conditions - p. 491 36. Chapter 24. Resveratrol effects on skeletal muscle mitochondria and contractile function - p. 543 37. Chapter 25. Antiaging effects of natural agents in the skin: Focus on mitochondria - p. 557 38. Chapter 26. Role of quercetin in the glial mitochondria: Implications for health and disease - p. 577 39. Chapter 27. The therapeutic effects of lycopene on mitochondrial function in human diseases - p. 593 40. Chapter 28. Ascorbic acid and the mitochondria - p. 613 41. Chapter 29. Soy isoflavones, mitochondria and cell fate - p. 625 42. Chapter 30. Resveratrol and brain mitochondria - p. 645 43. Chapter 31. Plant-derived molecules for the prevention and treatment of mitochondria-related diseases - p. 693 44. Chapter 32. Mitochondrial toxicity induced by plant molecules - p. 709 45. Chapter 33. Mitohormesis - p. 729 46. Index - p. 747

Descripcion
Descripción

Mitochondrial Physiology and Vegetal Molecules: Therapeutic potential of natural compounds on mitochondrial health provides a comprehensive overview of mitochondrial physiology throughout the human life span, as well as the effect of molecules of vegetal origin on mitochondrial health. The editor has lined up a team of worldwide experts to cover the most exciting and high-impact advancements of research in this area.

This book is structured into two parts that provide a balance of both foundational and applied content. Part I provides an overview of mitochondrial physiology including its structure, dynamics, biogenesis, membranes, DNA transcription, and translation in the mitochondria. Part I also covers other themes such as apoptosis. Part II then covers the effect of specific vegetable-derived molecules on mitochondrial health, including anthocyanins, caffeine, cannabinoids, carnosic and rosmarinic acids, citrus flavonoids, polyphenols, pterostilbene, resveratrol, and sulforaphane, among others.

Mitochondrial Physiology and Vegetal Molecules: Therapeutic potential of natural compounds on mitochondrial health is a complete resource for researchers in this exciting field. Its comprehensive coverage makes it particularly interesting to bioscience researchers willing to understand the foundations of mitochondrial physiology throughout the human life span. Clinician researchers, MDs, nutritionists, pharmacologists, and sports scientists may be attracted to the detailed information on the health effects of vegetal origin molecules on the organelle.

  • Contains detailed information on plant products and their effect on mitochondria
  • Proposes therapies and reviews mechanisms of absorption at the cellular level
  • Discusses the limited bioavailability of plant molecules/compounds in the human organism
  • Includes coverage of specific conditions such as Sports and affective disorders, among others
  • Presents the protective effects of plant products in mitochondrial health through all stages of life

1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iii 6. Dedication - p. iii 7. Contributors - p. xxv 8. About the editor - p. xxxiii 9. Preface - p. xxxvii 10. Acknowledgments - p. xli 11. Part I: Overview of mitochondrial physiology - p. xli 12. Chapter 1. Mitochondria: Ultrastructure, dynamics, biogenesis, and main functions - p. 3 13. Chapter 2. Mitochondrial biogenesis and mitophagy - p. 35 14. Chapter 3. DNA transcription and translation in mitochondria - p. 91 15. Chapter 4. Mitochondrial redox biology: Reactive species production and antioxidant defenses - p. 105 16. Chapter 5. Mitochondria and apoptosis - p. 127 17. Chapter 6. Mitochondria-associated membranes in the maintenance of cell homeostasis - p. 151 18. Part II: The effects of plant molecules on the mitochondria in health and disease - p. 169 19. Chapter 7. Biopharmaceutical properties of natural products - p. 173 20. Chapter 8. Carnosic acid and brain mitochondria - p. 191 21. Chapter 9. Rosmarinic acid and mitochondria - p. 215 22. Chapter 10. Sulforaphane and mitochondria - p. 233 23. Chapter 11. Cannabinoids and mitochondria - p. 247 24. Chapter 12. Anthocyanins, effects in mitochondria and metabolism - p. 267 25. Chapter 13. Preclinical evidence of the therapeutic role of pterostilbene: Focus on the mitochondria - p. 301 26. Chapter 14. Polyphenols attenuate mitochondrial dysfunction induced by amyloid peptides - p. 324 27. Chapter 15. Plant molecules to treat eye mitochondria - p. 339 28. Chapter 16. Mitochondria as a target for monoterpenes - p. 359 29. Baccharis trimera phytochemicals and the mitochondria - p. 379 30. Chapter 18. Citrus flavonoids and the mitochondria - p. 395 31. Chapter 19. Caffeine and mitochondria with a focus on the central nervous system - p. 413 32. Chapter 20. Curcumin and mitochondria - p. 439 33. Chapter 21. Catechins, neuroprotection, and brain mitochondria - p. 455 34. Chapter 22. The effects of catechins on the cardiac mitochondria - p. 471 35. Chapter 23. Possible roles of garlic and its bioactive components on mitochondrial function in physiological and pathological conditions - p. 491 36. Chapter 24. Resveratrol effects on skeletal muscle mitochondria and contractile function - p. 543 37. Chapter 25. Antiaging effects of natural agents in the skin: Focus on mitochondria - p. 557 38. Chapter 26. Role of quercetin in the glial mitochondria: Implications for health and disease - p. 577 39. Chapter 27. The therapeutic effects of lycopene on mitochondrial function in human diseases - p. 593 40. Chapter 28. Ascorbic acid and the mitochondria - p. 613 41. Chapter 29. Soy isoflavones, mitochondria and cell fate - p. 625 42. Chapter 30. Resveratrol and brain mitochondria - p. 645 43. Chapter 31. Plant-derived molecules for the prevention and treatment of mitochondria-related diseases - p. 693 44. Chapter 32. Mitochondrial toxicity induced by plant molecules - p. 709 45. Chapter 33. Mitohormesis - p. 729 46. Index - p. 747

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Ficha Técnica