Microbial biofilms: Role in Human Infectious Diseases focuses on new and emerging concepts in microbial biofilm research, such as the mechanisms of biofilm formation, biofilm-induced pathogenesis, biofilm detection/and diagnosis, gene exchange within biofilms, strategies to control microbial biofilms and the burden of biofilm associated infections. In addition, it highlights the various anti-biofilm strategies such as surface coating, signal quenching, novel compounds that can be translated to curb biofilm-associated infections and the escalation of antimicrobial resistance determinants.
Microbial biofilms can be a serious problem in medical settings as they are associated with significant mortality and morbidity. Infection related to biofilms increases recovery time and the cost of disease management. Biofilms are resistant to known antibiotics and human defense mechanism. In addition, due to close proximity of microbes within biofilms, increase genetic transformation has been detected results in increases frequency of antibiotic gene spread. With the advancement in science and technology, novel strategies have been proposed to combat the impact of biofilms on human health.
1. Microbial Biofilms - p. Page i 2. Cover - p. Page i 3. Title page - p. Page ii 4. Table of Contents - p. Page iii 5. Copyright - p. Page iii 6. Contents - p. Page vi 7. List of contributors - p. Page vii 8. List of Illustrations - p. Page viii 9. List of Tables - p. Page ix 10. 1 : Application of nanoparticles to combat dental biofilms - p. Page ix 11. 2 : Streptococcus biofilms: role in human infectious diseases - p. Page 17 12. 3 : Single-species and multispecies biofilms causing infections - p. Page 32 13. 4 : Gut microbiota: role of biofilms in human health - p. Page 50 14. 5 : Natural compounds to combat microbial biofilms - p. Page 76 15. 6 : Vaginal microbiota biofilm in pregnancy and birth outcome: function and prospects - p. Page 112 16. 7 : Microbial biofilms and their role in acute and chronic pathogenesis - p. Page 131 17. 8 : Surface modification: strategies to prevent microbial growth on medical implants - p. Page 148 18. 9 : Microbial biofilms and the skin microbiome - p. Page 162 19. 10 : Cell-to-cell interaction and cell signaling in biofilm formation - p. Page 174 20. 11 : A concise review on genes involved in biofilm-related disease and differential gene expression in medical-related biofilms - p. Page 206 21. 12 : Next-generation sequencing: role in microbial biofilm study - p. Page 228 22. 13 : Electrical signaling in growth dynamics of microbial biofilms - p. Page 245 23. Index - p. Page 259
Microbial biofilms: Role in Human Infectious Diseases focuses on new and emerging concepts in microbial biofilm research, such as the mechanisms of biofilm formation, biofilm-induced pathogenesis, biofilm detection/and diagnosis, gene exchange within biofilms, strategies to control microbial biofilms and the burden of biofilm associated infections. In addition, it highlights the various anti-biofilm strategies such as surface coating, signal quenching, novel compounds that can be translated to curb biofilm-associated infections and the escalation of antimicrobial resistance determinants.
Microbial biofilms can be a serious problem in medical settings as they are associated with significant mortality and morbidity. Infection related to biofilms increases recovery time and the cost of disease management. Biofilms are resistant to known antibiotics and human defense mechanism. In addition, due to close proximity of microbes within biofilms, increase genetic transformation has been detected results in increases frequency of antibiotic gene spread. With the advancement in science and technology, novel strategies have been proposed to combat the impact of biofilms on human health.
1. Microbial Biofilms - p. Page i 2. Cover - p. Page i 3. Title page - p. Page ii 4. Table of Contents - p. Page iii 5. Copyright - p. Page iii 6. Contents - p. Page vi 7. List of contributors - p. Page vii 8. List of Illustrations - p. Page viii 9. List of Tables - p. Page ix 10. 1 : Application of nanoparticles to combat dental biofilms - p. Page ix 11. 2 : Streptococcus biofilms: role in human infectious diseases - p. Page 17 12. 3 : Single-species and multispecies biofilms causing infections - p. Page 32 13. 4 : Gut microbiota: role of biofilms in human health - p. Page 50 14. 5 : Natural compounds to combat microbial biofilms - p. Page 76 15. 6 : Vaginal microbiota biofilm in pregnancy and birth outcome: function and prospects - p. Page 112 16. 7 : Microbial biofilms and their role in acute and chronic pathogenesis - p. Page 131 17. 8 : Surface modification: strategies to prevent microbial growth on medical implants - p. Page 148 18. 9 : Microbial biofilms and the skin microbiome - p. Page 162 19. 10 : Cell-to-cell interaction and cell signaling in biofilm formation - p. Page 174 20. 11 : A concise review on genes involved in biofilm-related disease and differential gene expression in medical-related biofilms - p. Page 206 21. 12 : Next-generation sequencing: role in microbial biofilm study - p. Page 228 22. 13 : Electrical signaling in growth dynamics of microbial biofilms - p. Page 245 23. Index - p. Page 259
