Molecular and Cellular Therapies for Motor Neuron Diseases discusses the basics of the diseases, also covering advances in research and clinical trials. The book provides a resource for students that will help them learn the basics in a detailed manner that is required for scientists and clinicians.
Users will find a comprehensive overview of the background of Amyotrophic Lateral Sclerosis (ALS/Lou Gehrig’s Disease) and Spinal Muscular Atrophy (SMA), along with the current understanding of their genetics and mechanisms. In addition, the book details gene and cell therapies that have been developed and their translation to clinical trials.
1. Chapter 5 : An Introduction to the Natural History, Genetic Mapping, and Clinical Spectrum of Spinal Muscular Atrophy - p. Page 88 2. Chapter 6 : Genetics of Spinal Muscular Atrophy - p. Page 116 3. Chapter 7 : Introduction to Gene and Stem-Cell Therapy - p. Page 135 4. Chapter 8 : Gene Therapy for Amyotrophic Lateral Sclerosis: Therapeutic Transgenes - p. Page 157 5. Chapter 9 : Stem Cell Therapy for Amyotrophic Lateral Sclerosis - p. Page 194 6. Chapter 10 : Gene Therapy for Spinal Muscular Atrophy - p. Page 223 7. Chapter 11 : Cellular Therapy for Spinal Muscular Atrophy: Pearls and Pitfalls - p. Page 246 8. Chapter 12 : Clinical Trials to Date - p. Page 270 9. Index - p. Page 305
Molecular and Cellular Therapies for Motor Neuron Diseases discusses the basics of the diseases, also covering advances in research and clinical trials. The book provides a resource for students that will help them learn the basics in a detailed manner that is required for scientists and clinicians.
Users will find a comprehensive overview of the background of Amyotrophic Lateral Sclerosis (ALS/Lou Gehrig’s Disease) and Spinal Muscular Atrophy (SMA), along with the current understanding of their genetics and mechanisms. In addition, the book details gene and cell therapies that have been developed and their translation to clinical trials.
1. Chapter 5 : An Introduction to the Natural History, Genetic Mapping, and Clinical Spectrum of Spinal Muscular Atrophy - p. Page 88 2. Chapter 6 : Genetics of Spinal Muscular Atrophy - p. Page 116 3. Chapter 7 : Introduction to Gene and Stem-Cell Therapy - p. Page 135 4. Chapter 8 : Gene Therapy for Amyotrophic Lateral Sclerosis: Therapeutic Transgenes - p. Page 157 5. Chapter 9 : Stem Cell Therapy for Amyotrophic Lateral Sclerosis - p. Page 194 6. Chapter 10 : Gene Therapy for Spinal Muscular Atrophy - p. Page 223 7. Chapter 11 : Cellular Therapy for Spinal Muscular Atrophy: Pearls and Pitfalls - p. Page 246 8. Chapter 12 : Clinical Trials to Date - p. Page 270 9. Index - p. Page 305
