Molecular Nutrition: Vitamins presents the nutritional and molecular aspects of vitamins with a specific focus on vitamins A, B1 (thiamine), B2 (riboflavin), B# (niacin), B5 (pantothenic acid), B6, (pyridoxine), B7 (biotin), B9 (folate), B12 (colbamin), C, D, E, and K. As part of the Molecular Nutrition series, this book discusses introductory aspects and general coverage of vitamins and nutrition, the molecular biology of the cell, including signaling, transporters, oxidative stress, receptors, uptake, immunity, proliferation, endoplasmic reticulum, differentiation, carcinogenesis and apoptosis. Final sections cover genetic machinery and its function, transcriptional processes, homeostasis genes, cancer, gene expression, mutations, and more.
Emerging fields of molecular biology and important discoveries related to diet and nutritional health are also covered, rounding out the book.
1. Cover image - p. Cover 2. Title page - p. iii 3. Table of Contents - p. iii 4. Copyright - p. iv 5. List of Contributors - p. xvii 6. Series Preface - p. xxv 7. Preface - p. xxvii 8. Part I: General and Introductory Aspects - p. xxviii 9. Chapter 1. Reference dietary requirements of vitamins in different stages of life - p. 3 10. Chapter 2. Bioactive vitamin–metal compounds: other potential applications of vitamins - p. 33 11. Chapter 3. Vitamin E: an overview - p. 51 12. Chapter 4. Vitamin E: structure and forms - p. 67 13. Chapter 5. Riboflavin-enriched fermented soy milk for redox-mediated gut modulation: in the search of novel prebiotics - p. 91 14. Chapter 6. A review of vitamin B12 - p. 105 15. Chapter 7. Nutrigenomic aspects of dietary pyridoxine (vitamin B6) and selenium interaction and their implications in reproduction - p. 131 16. Chapter 8. Vitamin K2 is a key regulator of clinically relevant molecular processes - p. 153 17. Chapter 9. Biotin status screening - p. 173 18. Part II: Molecular Biology of the Cell - p. 180 19. Chapter 10. Vitamin B1 and the pyruvate dehydrogenase complex - p. 185 20. Chapter 11. Thiamine, oxidative stress, and ethanol - p. 207 21. Chapter 12. Riboflavin (vitamin B2) and mitochondrial energy - p. 225 22. Chapter 13. Linking homocysteine, B vitamins, and choline to ischemic stroke risk - p. 245 23. Chapter 14. Niacin and hyperlipidemia - p. 263 24. Chapter 15. Novel preventive mechanisms of vitamin B6 against inflammation, inflammasome, and chronic diseases - p. 283 25. Chapter 16. New properties of vitamin B6 or pyridoxine in experimental oxidative stress in the brain - p. 301 26. Chapter 17. Nonalcoholic fatty liver disease and use of folate - p. 323 27. Chapter 18. Folates transport in placentas - p. 345 28. Chapter 19. Cobalamin (vitamin B12) malabsorption - p. 367 29. Chapter 20. γ-Tocotrienol reversal of the Warburg effect in breast cancer cells is associated with 5′-AMP-activated kinase activation - p. 387 30. Chapter 21. Vitamin D receptor activation and prevention of arterial aging - p. 409 31. Chapter 22. Vitamin D in immune regulation and diabetes mellitus - p. 427 32. Chapter 23. Vitamin E: nutritional aspects - p. 447 33. Chapter 24. Vitamin E: metabolism and molecular aspects - p. 487 34. Chapter 25. Linking vitamin E and nitric oxide in liver disease - p. 519 35. Chapter 26. Vitamin E and reproductive health - p. 543 36. Chapter 27. Vitamins in chronic kidney disease - p. 561 37. Chapter 28. Inflammatory bowel disorders and fat-soluble vitamins - p. 583 38. Chapter 29. Prostate cancer and applications of vitamin K - p. 613 39. Part III: Genetic Machinery and its Function - p. 626 40. Chapter 30. Vitamins and epigenetics - p. 633 41. Chapter 31. Transcriptional control of cells by vitamin D and its role in liver health and disease - p. 651 42. Chapter 32. Vitamin B3: niacin and transcriptome analysis in relation to the GPR109A receptor - p. 673 43. Chapter 33. Vitamin C: epigenetic roles and cancer - p. 691 44. Author Index - p. 711 45. Subject Index - p. 735
Molecular Nutrition: Vitamins presents the nutritional and molecular aspects of vitamins with a specific focus on vitamins A, B1 (thiamine), B2 (riboflavin), B# (niacin), B5 (pantothenic acid), B6, (pyridoxine), B7 (biotin), B9 (folate), B12 (colbamin), C, D, E, and K. As part of the Molecular Nutrition series, this book discusses introductory aspects and general coverage of vitamins and nutrition, the molecular biology of the cell, including signaling, transporters, oxidative stress, receptors, uptake, immunity, proliferation, endoplasmic reticulum, differentiation, carcinogenesis and apoptosis. Final sections cover genetic machinery and its function, transcriptional processes, homeostasis genes, cancer, gene expression, mutations, and more.
Emerging fields of molecular biology and important discoveries related to diet and nutritional health are also covered, rounding out the book.
1. Cover image - p. Cover 2. Title page - p. iii 3. Table of Contents - p. iii 4. Copyright - p. iv 5. List of Contributors - p. xvii 6. Series Preface - p. xxv 7. Preface - p. xxvii 8. Part I: General and Introductory Aspects - p. xxviii 9. Chapter 1. Reference dietary requirements of vitamins in different stages of life - p. 3 10. Chapter 2. Bioactive vitamin–metal compounds: other potential applications of vitamins - p. 33 11. Chapter 3. Vitamin E: an overview - p. 51 12. Chapter 4. Vitamin E: structure and forms - p. 67 13. Chapter 5. Riboflavin-enriched fermented soy milk for redox-mediated gut modulation: in the search of novel prebiotics - p. 91 14. Chapter 6. A review of vitamin B12 - p. 105 15. Chapter 7. Nutrigenomic aspects of dietary pyridoxine (vitamin B6) and selenium interaction and their implications in reproduction - p. 131 16. Chapter 8. Vitamin K2 is a key regulator of clinically relevant molecular processes - p. 153 17. Chapter 9. Biotin status screening - p. 173 18. Part II: Molecular Biology of the Cell - p. 180 19. Chapter 10. Vitamin B1 and the pyruvate dehydrogenase complex - p. 185 20. Chapter 11. Thiamine, oxidative stress, and ethanol - p. 207 21. Chapter 12. Riboflavin (vitamin B2) and mitochondrial energy - p. 225 22. Chapter 13. Linking homocysteine, B vitamins, and choline to ischemic stroke risk - p. 245 23. Chapter 14. Niacin and hyperlipidemia - p. 263 24. Chapter 15. Novel preventive mechanisms of vitamin B6 against inflammation, inflammasome, and chronic diseases - p. 283 25. Chapter 16. New properties of vitamin B6 or pyridoxine in experimental oxidative stress in the brain - p. 301 26. Chapter 17. Nonalcoholic fatty liver disease and use of folate - p. 323 27. Chapter 18. Folates transport in placentas - p. 345 28. Chapter 19. Cobalamin (vitamin B12) malabsorption - p. 367 29. Chapter 20. γ-Tocotrienol reversal of the Warburg effect in breast cancer cells is associated with 5′-AMP-activated kinase activation - p. 387 30. Chapter 21. Vitamin D receptor activation and prevention of arterial aging - p. 409 31. Chapter 22. Vitamin D in immune regulation and diabetes mellitus - p. 427 32. Chapter 23. Vitamin E: nutritional aspects - p. 447 33. Chapter 24. Vitamin E: metabolism and molecular aspects - p. 487 34. Chapter 25. Linking vitamin E and nitric oxide in liver disease - p. 519 35. Chapter 26. Vitamin E and reproductive health - p. 543 36. Chapter 27. Vitamins in chronic kidney disease - p. 561 37. Chapter 28. Inflammatory bowel disorders and fat-soluble vitamins - p. 583 38. Chapter 29. Prostate cancer and applications of vitamin K - p. 613 39. Part III: Genetic Machinery and its Function - p. 626 40. Chapter 30. Vitamins and epigenetics - p. 633 41. Chapter 31. Transcriptional control of cells by vitamin D and its role in liver health and disease - p. 651 42. Chapter 32. Vitamin B3: niacin and transcriptome analysis in relation to the GPR109A receptor - p. 673 43. Chapter 33. Vitamin C: epigenetic roles and cancer - p. 691 44. Author Index - p. 711 45. Subject Index - p. 735
