Molecular Pharmaceutics and Nano Drug Delivery: Fundamentals and Challenges provides a thorough resource for both beginners and established scientists, bringing fundamental knowledge about key challenges of these carriers down to the molecular level. The book satisfies the need of availability of literature at single platform with the detailed knowledge to understand crucial aspects, such as regulatory, clinical, toxicological and the formulation requirements of these carriers. This is a valuable resource for graduates, pharmaceutical researchers and anyone working on aspects of pharmaceutics, molecular pharmaceutics and nano-drug/gene delivery.
So called ‘novel drug delivery systems’ are numerous, with each having different approaches to their production, characterization and evaluation. The proper understanding of these dosage forms, as well as their critical attributes such as toxicity and regulatory requirements are aspects which researchers should know before they begin working on these carriers. This book provides this critical information.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. List of contributors - p. ix 7. Preface - p. xiii 8. Chapter 1. Protein and enzyme-based nanoformulations - p. 1 9. Chapter 2. Vaccines and sera - p. 15 10. Chapter 3. Aptamers and antisense oligonucleotide-based delivery - p. 63 11. Chapter 4. Monoclonal antibodies: recent development in drug delivery - p. 79 12. Chapter 5. Hormonal delivery systems - p. 103 13. Chapter 6. Vesicular drug delivery systems: a novel approach in current nanomedicine - p. 135 14. Chapter 7. Polymeric micelles in drug delivery and targeting - p. 161 15. Chapter 8. Physicochemical characterization of drug delivery systems based on nanomaterials - p. 183 16. Chapter 9. Inorganic and metal-based nanoparticles - p. 203 17. Chapter 10. Dendrimers: promises and challenges in drug delivery - p. 237 18. Chapter 11. Development of advanced diagnostic platform for detection of infectious diseases - p. 269 19. Chapter 12. Fundamentals of a targeted drug delivery system - p. 289 20. Chapter 13. Assessment of nanotoxicology through in vitro techniques and image-based assays - p. 311 21. Chapter 14. Gene therapy: advocacies, perspectives, and ethical provocations - p. 341 22. Index - p. 365
Molecular Pharmaceutics and Nano Drug Delivery: Fundamentals and Challenges provides a thorough resource for both beginners and established scientists, bringing fundamental knowledge about key challenges of these carriers down to the molecular level. The book satisfies the need of availability of literature at single platform with the detailed knowledge to understand crucial aspects, such as regulatory, clinical, toxicological and the formulation requirements of these carriers. This is a valuable resource for graduates, pharmaceutical researchers and anyone working on aspects of pharmaceutics, molecular pharmaceutics and nano-drug/gene delivery.
So called ‘novel drug delivery systems’ are numerous, with each having different approaches to their production, characterization and evaluation. The proper understanding of these dosage forms, as well as their critical attributes such as toxicity and regulatory requirements are aspects which researchers should know before they begin working on these carriers. This book provides this critical information.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. List of contributors - p. ix 7. Preface - p. xiii 8. Chapter 1. Protein and enzyme-based nanoformulations - p. 1 9. Chapter 2. Vaccines and sera - p. 15 10. Chapter 3. Aptamers and antisense oligonucleotide-based delivery - p. 63 11. Chapter 4. Monoclonal antibodies: recent development in drug delivery - p. 79 12. Chapter 5. Hormonal delivery systems - p. 103 13. Chapter 6. Vesicular drug delivery systems: a novel approach in current nanomedicine - p. 135 14. Chapter 7. Polymeric micelles in drug delivery and targeting - p. 161 15. Chapter 8. Physicochemical characterization of drug delivery systems based on nanomaterials - p. 183 16. Chapter 9. Inorganic and metal-based nanoparticles - p. 203 17. Chapter 10. Dendrimers: promises and challenges in drug delivery - p. 237 18. Chapter 11. Development of advanced diagnostic platform for detection of infectious diseases - p. 269 19. Chapter 12. Fundamentals of a targeted drug delivery system - p. 289 20. Chapter 13. Assessment of nanotoxicology through in vitro techniques and image-based assays - p. 311 21. Chapter 14. Gene therapy: advocacies, perspectives, and ethical provocations - p. 341 22. Index - p. 365
