Nanocarriers for Drug-Targeting Brain Tumors covers different types of nanocarriers and their design and development for targeting drugs to the brain. The book also presents case studies and the mechanism of action of nanocarriers in drug targeting to a specific site. This helps researchers and clinicians understand the design, development and mechanism of action of nanocarriers. As brain tumors continue to be a significant health problem globally, and very complex for targeting drugs, conventional dosage forms are not very effective and side-effects are a major concern. Functionalized nanocarriers can address these problems.
Furthermore, the targeting of nanocarriers is preferred for reducing toxicity and improving the effectiveness of the drugs. However, there is a need for understanding the design and development of formulation with the mechanism of action of nanocarriers for brain targeting.
1. Nanocarriers for Drug-Targeting Brain Tumors - p. Page i 2. Cover - p. Page i 3. Front Matter - p. Page i 4. Table of Contents - p. Page iv 5. Copyright - p. Page v 6. Dedication - p. Page vi 7. Contributors - p. Page vi 8. Preface - p. Page x 9. List of Illustrations - p. Page xii 10. List of Tables - p. Page xiii 11. 1 : An overview of the anatomy and physiology of the brain - p. Page xiii 12. 2 : Blood-brain barrier and central nervous system drug delivery: Challenges and opportunities - p. Page 24 13. 3 : Challenges in targeting to brain and brain tumors - p. Page 47 14. 4 : Potential targeting sites in brain and brain tumors - p. Page 64 15. 5 : Drug resistance problems in chemotherapy - p. Page 106 16. 6 : An overview on nanocarriers - p. Page 130 17. 7 : Biomedical applications of nanocarriers in brain tumor targeting - p. Page 189 18. 8 : Solid lipid nanoparticles based drug delivery for targeting brain tumors - p. Page 223 19. 9 : Nanostructured lipid carriers as an alternative carrier with high drug loading for targeting to brain tumors - p. Page 264 20. 10 : Liposomes in drug targeting to brain tumors - p. Page 294 21. 11 : Niosomes based drug delivery in targeting brain tumors - p. Page 321 22. 12 : Nanoemulsions as effective carriers for targeting brain tumors - p. Page 339 23. 13 : Mechanism of polymeric micelles for drug targeting to brain tumors - p. Page 359 24. 14 : Dendrimers as carriers for active targeting of brain tumors - p. Page 394 25. 15 : Multifunctional polymeric nanocarriers for targeting brain tumors - p. Page 422 26. 16 : Polymersomes for targeting to brain tumors - p. Page 447 27. 17 : Development and applications of gold nanoparticles for targeting brain tumors - p. Page 476 28. 18 : Gold nanoparticles in cancer theranostics - p. Page 506 29. 19 : Silver nanoparticles in brain tumor targeting - p. Page 521 30. 20 : Hybrid nanoparticles to cross the blood–brain barrier - p. Page 557 31. 21 : Targeting of lipid/polymeric (hybrid) nanoparticles to brain tumors - p. Page 583 32. 22 : Nano-enabled systems for neural tissue regenerative applications - p. Page 617 33. 23 : Multifunctional liposome-quantum dot hybrid nanocarriers for drug targeting to brain tumors - p. Page 641 34. 24 : Drug-loaded nanoclusters for brain targeting - p. Page 671 35. 25 : Nanomedicines for tropical diseases affecting the central nervous system - p. Page 691 36. 26 : Brain specific delivery of phytoconstituents through nanodrug wagons approach - p. Page 721 37. 27 : Multifunctional nanocarrier systems targeting brain tumors: A review - p. Page 748 38. 28 : Expert opinion on current challenges and future directions of nanocarriers for brain targeted drug delivery - p. Page 769 39. 29 : Biological nanodrugs for brain targeting - p. Page 793 40. Index - p. Page 816
Nanocarriers for Drug-Targeting Brain Tumors covers different types of nanocarriers and their design and development for targeting drugs to the brain. The book also presents case studies and the mechanism of action of nanocarriers in drug targeting to a specific site. This helps researchers and clinicians understand the design, development and mechanism of action of nanocarriers. As brain tumors continue to be a significant health problem globally, and very complex for targeting drugs, conventional dosage forms are not very effective and side-effects are a major concern. Functionalized nanocarriers can address these problems.
Furthermore, the targeting of nanocarriers is preferred for reducing toxicity and improving the effectiveness of the drugs. However, there is a need for understanding the design and development of formulation with the mechanism of action of nanocarriers for brain targeting.
1. Nanocarriers for Drug-Targeting Brain Tumors - p. Page i 2. Cover - p. Page i 3. Front Matter - p. Page i 4. Table of Contents - p. Page iv 5. Copyright - p. Page v 6. Dedication - p. Page vi 7. Contributors - p. Page vi 8. Preface - p. Page x 9. List of Illustrations - p. Page xii 10. List of Tables - p. Page xiii 11. 1 : An overview of the anatomy and physiology of the brain - p. Page xiii 12. 2 : Blood-brain barrier and central nervous system drug delivery: Challenges and opportunities - p. Page 24 13. 3 : Challenges in targeting to brain and brain tumors - p. Page 47 14. 4 : Potential targeting sites in brain and brain tumors - p. Page 64 15. 5 : Drug resistance problems in chemotherapy - p. Page 106 16. 6 : An overview on nanocarriers - p. Page 130 17. 7 : Biomedical applications of nanocarriers in brain tumor targeting - p. Page 189 18. 8 : Solid lipid nanoparticles based drug delivery for targeting brain tumors - p. Page 223 19. 9 : Nanostructured lipid carriers as an alternative carrier with high drug loading for targeting to brain tumors - p. Page 264 20. 10 : Liposomes in drug targeting to brain tumors - p. Page 294 21. 11 : Niosomes based drug delivery in targeting brain tumors - p. Page 321 22. 12 : Nanoemulsions as effective carriers for targeting brain tumors - p. Page 339 23. 13 : Mechanism of polymeric micelles for drug targeting to brain tumors - p. Page 359 24. 14 : Dendrimers as carriers for active targeting of brain tumors - p. Page 394 25. 15 : Multifunctional polymeric nanocarriers for targeting brain tumors - p. Page 422 26. 16 : Polymersomes for targeting to brain tumors - p. Page 447 27. 17 : Development and applications of gold nanoparticles for targeting brain tumors - p. Page 476 28. 18 : Gold nanoparticles in cancer theranostics - p. Page 506 29. 19 : Silver nanoparticles in brain tumor targeting - p. Page 521 30. 20 : Hybrid nanoparticles to cross the blood–brain barrier - p. Page 557 31. 21 : Targeting of lipid/polymeric (hybrid) nanoparticles to brain tumors - p. Page 583 32. 22 : Nano-enabled systems for neural tissue regenerative applications - p. Page 617 33. 23 : Multifunctional liposome-quantum dot hybrid nanocarriers for drug targeting to brain tumors - p. Page 641 34. 24 : Drug-loaded nanoclusters for brain targeting - p. Page 671 35. 25 : Nanomedicines for tropical diseases affecting the central nervous system - p. Page 691 36. 26 : Brain specific delivery of phytoconstituents through nanodrug wagons approach - p. Page 721 37. 27 : Multifunctional nanocarrier systems targeting brain tumors: A review - p. Page 748 38. 28 : Expert opinion on current challenges and future directions of nanocarriers for brain targeted drug delivery - p. Page 769 39. 29 : Biological nanodrugs for brain targeting - p. Page 793 40. Index - p. Page 816
