Nanotherapeutics in Cancer Vaccination and Challenges consolidates the current research on cancer nanomedicine and therapeutic cancer vaccination to explore the most effective and promising avenues. The book covers cancer vaccines before exploring nanotherapeutics, DNA and mRNA vaccines in cancer treatment. Finally, it considers regulatory and industrial perspectives on cancer vaccination and nanotherapeutics. This resource will be useful for pharmaceutical scientists and researchers focused on biomedical engineering, chemical engineering, vaccine development, and cancer immunotherapy, along with advanced students in these subjects.
Cancer is arguably the most complex and challenging disease known to mankind. Over the last two-decades, significant advancements have been made in new and novel concepts of cancer nanomedicines. Therapeutic cancer vaccines may be utilized to inhibit further growth of advanced cancers and/or relapsed tumors that are refractory to conventional therapies, such as surgery, radiation therapy and chemotherapy.
1. Nanotherapeutics in Cancer Vaccination and Challenges - p. iii 2. Cover - p. iii 3. Title Page - p. iii 4. Copyright - p. iv 5. Table of Contents - p. iv 6. Dedication - p. v 7. List of Contributors - p. xix 8. Preface - p. xxv 9. Acknowledgments - p. xxix 10. Chapter 1 Cancer vaccines - p. 1 11. Chapter 2 Inorganic nanoparticulate carriers in management of cancer - p. 13 12. Chapter 3 Recent developments in cancer vaccines - p. 29 13. Chapter 4 Application of nanotechnology assisted devices in cancer treatment - p. 77 14. Chapter 5 Advancement in protein-based nanocarriers in targeted anticancer therapy - p. 95 15. Chapter 6 Elastic liposomes as transcutaneous DNA vaccine vectors - p. 103 16. Chapter 7 Nanotechnology-based manipulation of dendritic cells for enhanced immunotherapy strategies - p. 129 17. Chapter 8 Peptide-based anticancer targeted therapeutics - p. 149 18. Chapter 9 Polyplexes-based delivery systems for cancer vaccine delivery - p. 167 19. Chapter 10 Lipopolyplex-based delivery system for cancer vaccine delivery - p. 193 20. Chapter 11 Inorganic nanoparticulate carriers in cancer vaccination - p. 217 21. Chapter 12 Functional nanomaterials and nanocomposite in cancer vaccines - p. 241 22. Chapter 13 DNA vaccines for cancer treatment - p. 259 23. Chapter 14 mRNA-based nanovaccines as newer treatment modalities in cancer - p. 279 24. Chapter 15 Cancer immunotherapy - p. 295 25. Chapter 16 Product development and scale-up challenges in cancer vaccine development - p. 313 26. Chapter 17 Regulatory landscape in the approval of cancer vaccine - p. 325 27. Chapter 18 Cross-presentation-based nanovaccine for cancer immunotherapy - p. 349 28. Chapter 19 Immunotherapy-based cancer vaccines - p. 397 29. Chapter 20 Therapeutic peptides in anticancer therapy - p. 413 30. Chapter 21 Inorganic nanoconjugates for cancer theragnosis - p. 427 31. Index - p. 447
Nanotherapeutics in Cancer Vaccination and Challenges consolidates the current research on cancer nanomedicine and therapeutic cancer vaccination to explore the most effective and promising avenues. The book covers cancer vaccines before exploring nanotherapeutics, DNA and mRNA vaccines in cancer treatment. Finally, it considers regulatory and industrial perspectives on cancer vaccination and nanotherapeutics. This resource will be useful for pharmaceutical scientists and researchers focused on biomedical engineering, chemical engineering, vaccine development, and cancer immunotherapy, along with advanced students in these subjects.
Cancer is arguably the most complex and challenging disease known to mankind. Over the last two-decades, significant advancements have been made in new and novel concepts of cancer nanomedicines. Therapeutic cancer vaccines may be utilized to inhibit further growth of advanced cancers and/or relapsed tumors that are refractory to conventional therapies, such as surgery, radiation therapy and chemotherapy.
1. Nanotherapeutics in Cancer Vaccination and Challenges - p. iii 2. Cover - p. iii 3. Title Page - p. iii 4. Copyright - p. iv 5. Table of Contents - p. iv 6. Dedication - p. v 7. List of Contributors - p. xix 8. Preface - p. xxv 9. Acknowledgments - p. xxix 10. Chapter 1 Cancer vaccines - p. 1 11. Chapter 2 Inorganic nanoparticulate carriers in management of cancer - p. 13 12. Chapter 3 Recent developments in cancer vaccines - p. 29 13. Chapter 4 Application of nanotechnology assisted devices in cancer treatment - p. 77 14. Chapter 5 Advancement in protein-based nanocarriers in targeted anticancer therapy - p. 95 15. Chapter 6 Elastic liposomes as transcutaneous DNA vaccine vectors - p. 103 16. Chapter 7 Nanotechnology-based manipulation of dendritic cells for enhanced immunotherapy strategies - p. 129 17. Chapter 8 Peptide-based anticancer targeted therapeutics - p. 149 18. Chapter 9 Polyplexes-based delivery systems for cancer vaccine delivery - p. 167 19. Chapter 10 Lipopolyplex-based delivery system for cancer vaccine delivery - p. 193 20. Chapter 11 Inorganic nanoparticulate carriers in cancer vaccination - p. 217 21. Chapter 12 Functional nanomaterials and nanocomposite in cancer vaccines - p. 241 22. Chapter 13 DNA vaccines for cancer treatment - p. 259 23. Chapter 14 mRNA-based nanovaccines as newer treatment modalities in cancer - p. 279 24. Chapter 15 Cancer immunotherapy - p. 295 25. Chapter 16 Product development and scale-up challenges in cancer vaccine development - p. 313 26. Chapter 17 Regulatory landscape in the approval of cancer vaccine - p. 325 27. Chapter 18 Cross-presentation-based nanovaccine for cancer immunotherapy - p. 349 28. Chapter 19 Immunotherapy-based cancer vaccines - p. 397 29. Chapter 20 Therapeutic peptides in anticancer therapy - p. 413 30. Chapter 21 Inorganic nanoconjugates for cancer theragnosis - p. 427 31. Index - p. 447
