Covering every aspect of general pediatric practice, as well as details for many pediatric subspecialists, Nelson Textbook of Pediatrics, 22nd Edition, brings you fully up to date with everything from rapidly changing diagnostic and treatment protocols to new technologies to the wide range of biologic, psychologic, and social problems faced by children today. Edited and written by experts and prominent members of the pediatric medical community, this comprehensive two-volume reference covers both the science and art of pediatric practice. It remains the reference of choice among pediatricians, pediatric residents, and others involved in the care of young patients, delivering the information you need in a concise, easy-to-use format for everyday reference and study.
1. Chapter 557. Introduction to Glomerular Diseases - p. 3180 2. Section 2. Conditions Particularly Associated With Hematuria - p. 3183.e1 3. Chapter 558. Clinical Evaluation of the Child with Hematuria - p. 3184 4. Chapter 559. Isolated Glomerular Diseases Associated with Recurrent Gross Hematuria - p. 3187 5. Chapter 560. Multisystem Disease Associated with Hematuria - p. 3196 6. Chapter 561. Tubulointerstitial Disease Associated with Hematuria - p. 3205 7. Chapter 562. Vascular Diseases Associated with Hematuria - p. 3211 8. Chapter 563. Anatomic Abnormalities Associated with Hematuria - p. 3213 9. Chapter 564. Lower Urinary Tract Causes of Hematuria - p. 3217.e2 10. Section 3. Conditions Particularly Associated With Proteinuria - p. 3218.e2 11. Chapter 565. Clinical Evaluation of the Child with Proteinuria - p. 3218 12. Chapter 566. Conditions Associated with Proteinuria - p. 3220 13. Chapter 567. Nephrotic Syndrome - p. 3222 14. Section 4. Tubular Disorders - p. 3232.e2 15. Chapter 568. Tubular Function - p. 3233 16. Chapter 569. Renal Tubular Acidosis - p. 3234 17. Chapter 570. Nephrogenic Diabetes Insipidus - p. 3238 18. Chapter 571. Inherited Tubular Transport Abnormalities - p. 3240 19. Chapter 572. Renal Failure - p. 3242 20. Chapter 573. Renal Transplantation - p. 3253 21. Part XXII. Urologic Disorders in Infants and Children - p. 3259.e1 22. Chapter 574. Congenital Anomalies and Dysgenesis of the Kidneys - p. 3260 23. Chapter 575. Urinary Tract Infections - p. 3263 24. Chapter 576. Vesicoureteral Reflux - p. 3270 25. Chapter 577. Obstruction of the Urinary Tract - p. 3275 26. Chapter 578. Anomalies of the Bladder - p. 3285 27. Chapter 579. Neuropathic Bladder - p. 3288 28. Chapter 580. Enuresis and Voiding Dysfunction - p. 3291 29. Chapter 581. Anomalies of the Penis and Urethra - p. 3296 30. Chapter 582. Disorders and Anomalies of the Scrotal Contents - p. 3302 31. Chapter 583. Trauma to the Genitourinary Tract - p. 3309 32. Chapter 584. Urinary Lithiasis - p. 3311 33. Part XXIII. Gynecologic Problems of Childhood - p. 3316.e1 34. Chapter 585. Gynecologic History and Physical Examination - p. 3317 35. Chapter 586. Vulvovaginitis - p. 3320 36. Chapter 587. Vaginal Bleeding in the Prepubertal Child - p. 3326 37. Chapter 588. Breast Health - p. 3328 38. Chapter 589. Polycystic Ovary Syndrome and Hirsutism - p. 3334 39. Chapter 590. Gynecologic Neoplasms and Prevention Methods for Human Papillomavirus Infections in Adolescents - p. 3338 40. Chapter 591. Vulvovaginal and Müllerian Anomalies - p. 3347 41. Chapter 592. Gynecologic Care for Adolescents with Special Needs - p. 3355 42. Chapter 593. Female Genital Mutilation - p. 3357 43. The Endocrine System - p. 3358.e1 44. Section 1. Disorders of the Hypothalamus and Pituitary Gland - p. 3358.e1 45. Chapter 594. Hormones of the Hypothalamus and Pituitary - p. 3359 46. Chapter 595. Hypopituitarism - p. 3364 47. Chapter 596. Diabetes Insipidus - p. 3372 48. Chapter 597. Other Abnormalities of Arginine Vasopressin Metabolism and Action - p. 3375 49. Chapter 598. Hyperpituitarism - p. 3378 50. Chapter 599. Physiology of Puberty - p. 3385 51. Chapter 600. Disorders of Pubertal Development - p. 3386 52. Section 2. Disorders of the Thyroid Gland - p. 3399.e1 53. Chapter 601. Thyroid Development and Physiology - p. 3400 54. Chapter 602. Disorders of Thyroxine-Binding Globulin - p. 3400 55. Chapter 603. Hypothyroidism - p. 3402 56. Chapter 604. Thyroiditis - p. 3411 57. Chapter 605. Goiter - p. 3413 58. Chapter 606. Thyrotoxicosis - p. 3416 59. Chapter 607. Carcinoma of the Thyroid - p. 3422 60. Chapter 608. Autoimmune Polyglandular Syndromes - p. 3425 61. Chapter 609. Multiple Endocrine Neoplasia Syndromes - p. 3431 62. Section 3. Disorders of the Parathyroid Gland - p. 3432.e1 63. Chapter 610. Hormones and Peptides of Calcium Homeostasis and Bone Metabolism - p. 3433 64. Chapter 611. Hypoparathyroidism - p. 3434 65. Chapter 612. Pseudohypoparathyroidism - p. 3439 66. Chapter 613. Hyperparathyroidism - p. 3440 67. Section 4. Disorders of the Adrenal Gland - p. 3443.e1 68. Chapter 614. Physiology of the Adrenal Gland - p. 3444 69. Chapter 615. Adrenocortical Insufficiency and Altered Sensitivity to Corticosteroids - p. 3450 70. Chapter 616. Congenital Adrenal Hyperplasia and Related Disorders - p. 3462 71. Chapter 617. Adrenocortical Tumors and Masses - p. 3472 72. Chapter 618. Virilizing and Feminizing Adrenal Tumors - p. 3474.e1 73. Chapter 619. Cushing Syndrome - p. 3475 74. Chapter 620. Primary Aldosteronism - p. 3478 75. Chapter 621. Pheochromocytoma - p. 3480 76. Section 5. Disorders of the Gonads - p. 3480 77. Chapter 622. Development and Function of the Gonads - p. 3481 78. Chapter 623. Hypofunction of the Testes - p. 3487 79. Chapter 624. Pseudoprecocity Resulting from Tumors of the Testes - p. 3494 80. Chapter 625. Gynecomastia - p. 3495 81. Chapter 626. Hypofunction of the Ovaries - p. 3496 82. Chapter 627. Pseudoprecocity Resulting from Lesions of the Ovary - p. 3502 83. Chapter 628. Disorders of Sex Development - p. 3503 84. Section 6. Diabetes Mellitus in Children - p. 3513 85. Chapter 629. Diabetes Mellitus - p. 3515 86. 629.1. Classification of Diabetes Mellitus - p. 3515 87. 629.2. Type 1 Diabetes Mellitus (Immune Mediated) - p. 3517 88. 629.3. Type 2 Diabetes Mellitus - p. 3538 89. 629.4. Other Specific Types of Diabetes - p. 3542 90. Part XXV. The Nervous System - p. 3549.e4 91. Chapter 630. Neurologic Evaluation - p. 3550 92. Chapter 631. Congenital Anomalies of the Central Nervous System - p. 3561 93. Chapter 632. Deformational Plagiocephaly - p. 3584 94. Chapter 633. Seizures in Childhood - p. 3588 95. EVALUATION OF THE FIRST SEIZURE - p. 3589 96. 633.1. Febrile Seizures - p. 3595 97. 633.2. Unprovoked Seizures - p. 3597 98. 633.3. Focal Seizures and Related Epilepsy Syndromes - p. 3599 99. 633.4. Generalized Seizures and Related Epilepsy Syndromes - p. 3600 100. 633.5. Mechanisms of Seizures - p. 3603 101. 633.6. Treatment of Seizures and Epilepsy - p. 3604 102. 633.7. Neonatal Seizures - p. 3616 103. 633.8. Status Epilepticus - p. 3623 104. 633.9. Reflex Seizures (Stimulus-Precipitated Seizures) - p. 3629 105. 633.10. Nodding Syndrome - p. 3629 106. Chapter 634. Conditions That Mimic Seizures - p. 3631 107. Chapter 635. Headaches - p. 3639 108. Chapter 636. Neurocutaneous Syndromes - p. 3652 109. Chapter 637. Movement Disorders - p. 3664 110. Chapter 638. Encephalopathies - p. 3688 111. Chapter 639. Neurodegenerative Disorders of Childhood - p. 3711 112. Chapter 640. Demyelinating Disorders of the Central Nervous System - p. 3723 113. Chapter 641. Pediatric Stroke - p. 3742 114. Chapter 642. Central Nervous System Vasculitis - p. 3754 115. Chapter 643. Central Nervous System Infections - p. 3758 116. Chapter 644. Brain Abscess - p. 3779 117. Chapter 645. Idiopathic Intracranial Hypertension (Pseudotumor Cerebri) - p. 3782 118. Chapter 646. Spinal Cord Disorders - p. 3785 119. Part XXVI. Neuromuscular Disorders - p. 3790.e2 120. Chapter 647. Evaluation and Investigation of Neuromuscular Disorders - p. 3791 121. Chapter 648. Developmental Disorders of Muscle - p. 3805 122. Chapter 649. Muscular Dystrophies - p. 3828 123. Chapter 650. Endocrine and Toxic Myopathies - p. 3846 124. Chapter 651. Metabolic Myopathies and Channelopathies - p. 3848 125. Chapter 652. Disorders of Neuromuscular Transmission and of Motor Neurons - p. 3858 126. Chapter 653. Hereditary Motor-Sensory Neuropathies - p. 3876 127. Chapter 654. Toxic Neuropathies - p. 3892 128. Chapter 655. Autonomic Neuropathies - p. 3896 129. Chapter 656. Guillain-Barré Syndrome - p. 3900 130. Chapter 657. Bell Palsy - p. 3907 131. Part XXVII. Disorders of the Eye - p. 3908.e1 132. Chapter 658. Growth and Development of the Eye - p. 3908.e1 133. Chapter 659. Examination of the Eye - p. 3909 134. Chapter 660. Abnormalities of Refraction and Accommodation - p. 3912 135. Chapter 661. Disorders of Vision - p. 3915 136. Chapter 662. Abnormalities of Pupil and Iris - p. 3920 137. Chapter 663. Disorders of Eye Movement and Alignment - p. 3925 138. Chapter 664. Abnormalities of the Lids - p. 3933 139. Chapter 665. Disorders of the Lacrimal System - p. 3936 140. Chapter 666. Disorders of the Conjunctiva - p. 3939 141. Chapter 667. Abnormalities of the Cornea - p. 3943 142. Chapter 668. Abnormalities of the Lens - p. 3949 143. Chapter 669. Disorders of the Uveal Tract - p. 3952 144. Chapter 670. Disorders of the Retina and Vitreous - p. 3955 145. Chapter 671. Abnormalities of the Optic Nerve - p. 3963 146. Chapter 672. Childhood Glaucoma - p. 3968 147. Chapter 673. Orbital Abnormalities - p. 3971 148. Chapter 674. Orbital Infections - p. 3973 149. Chapter 675. Injuries to the Eye - p. 3976 150. Part XXVIII. The Ear - p. 3980.e1 151. Chapter 676. General Considerations and Evaluation of the Ear - p. 3981 152. Chapter 677. Hearing Loss - p. 3983 153. Chapter 678. Congenital Malformations of the Ear - p. 3995 154. Chapter 679. External Otitis (Otitis Externa) - p. 3999 155. Chapter 680. Otitis Media - p. 4003 156. Chapter 681. Acute Mastoiditis - p. 4016 157. Chapter 682. The Inner Ear and Diseases of the Bony Labyrinth - p. 4020 158. Chapter 683. Traumatic Injuries of the Ear and Temporal Bone - p. 4021 159. Chapter 684. Tumors of the Ear and Temporal Bone - p. 4023 160. Part XXIX. The Skin - p. 4024.e1 161. Chapter 685. Morphology of the Skin - p. 4025 162. Chapter 686. Dermatologic Evaluation of the Patient - p. 4027 163. Chapter 687. Principles of Dermatologic Therapy - p. 4038 164. Chapter 688. Dermatologic Diseases of the Neonate - p. 4041 165. Chapter 689. Cutaneous Defects - p. 4043 166. Chapter 690. Ectodermal Dysplasias - p. 4046 167. Chapter 691. Vascular Anomalies - p. 4050 168. Chapter 692. Cutaneous Nevi - p. 4061 169. Chapter 693. Hyperpigmented Lesions - p. 4067 170. Chapter 694. Hypopigmented Lesions - p. 4071 171. Chapter 695. Vesiculobullous Disorders - p. 4076 172. Chapter 696. Eczematous Disorders - p. 4087 173. Chapter 697. Photosensitivity - p. 4093 174. Chapter 698. Diseases of the Epidermis - p. 4098 175. Chapter 699. Disorders of Keratinization - p. 4110 176. Chapter 700. Diseases of the Dermis - p. 4119 177. Chapter 701. Diseases of Subcutaneous Tissue - p. 4129 178. Chapter 702. Disorders of the Sweat Glands - p. 4134 179. Chapter 703. Disorders of Hair - p. 4137 180. Chapter 704. Disorders of the Nails - p. 4142 181. Chapter 705. Disorders of the Mucous Membranes - p. 4147 182. Chapter 706. Cutaneous Bacterial Infections - p. 4150 183. Chapter 707. Cutaneous Fungal Infections - p. 4159 184. Chapter 708. Cutaneous Viral Infections - p. 4166 185. Chapter 709. Arthropod Bites and Infestations - p. 4170 186. Chapter 710. Acne - p. 4177 187. Chapter 711. Tumors of the Skin - p. 4185 188. Chapter 712. Nutritional Dermatoses - p. 4189 189. Bone and Joint Disorders - p. 4192.e1 190. Section 1. Orthopedic Problems - p. 4192.e1 191. Chapter 713. Orthopedic Growth and Development - p. 4193 192. Chapter 714. Orthopedic Evaluation of the Child - p. 4195 193. Chapter 715. The Foot and Toes - p. 4201 194. Chapter 716. Torsional and Angular Deformities of the Limb - p. 4212 195. Chapter 717. Leg-Length Discrepancy - p. 4219 196. Chapter 718. The Knee - p. 4224 197. Chapter 719. The Hip - p. 4231 198. Chapter 720. The Spine - p. 4242 199. Chapter 721. The Neck - p. 4258 200. Chapter 722. The Upper Limb - p. 4263 201. Chapter 723. Arthrogryposis - p. 4271 202. Chapter 724. Common Fractures - p. 4276 203. Chapter 725. Osteomyelitis - p. 4284 204. Chapter 726. Septic Arthritis - p. 4291 205. Section 2. Sports Medicine - p. 4294.e1 206. Chapter 727. Prevention of Injuries - p. 4294 207. Chapter 728. Management of Musculoskeletal Injury - p. 4297 208. Chapter 729. Sports-Related Traumatic Brain Injury (Concussion) - p. 4314 209. Chapter 730. Cervical Spine Injuries - p. 4318 210. Chapter 731. Heat Injuries - p. 4320 211. Chapter 732. Nutrition and Endocrine Conditions in Athletes - p. 4322 212. Chapter 733. Performance-Enhancing Aids - p. 4325 213. Chapter 734. Specific Sports and Associated Injuries - p. 4326 214. Section 3. The Skeletal Dysplasias - p. 4332.e2 215. Chapter 735. General Considerations in Skeletal Dysplasias - p. 4333 216. Chapter 736. Disorders Involving Cartilage Matrix Proteins - p. 4340 217. Chapter 737. Disorders Involving Transmembrane Receptors - p. 4345 218. Chapter 738. Disorders Involving Ion Transporters - p. 4347 219. Chapter 739. Disorders Involving Transcription Factors - p. 4349 220. Chapter 740. Osteopetrosis and Other Disorders Involving Defective Bone Resorption - p. 4350 221. Chapter 741. Other Inherited Disorders of Skeletal Development - p. 4354 222. Chapter 742. Osteogenesis Imperfecta - p. 4359 223. Section 4. Connective Tissue Disorders - p. 4363.e1 224. Chapter 743. Marfan Syndrome - p. 4363 225. Chapter 744. Ehlers-Danlos Syndrome - p. 4369 226. Chapter 745. Cutis Laxa - p. 4375 227. Section 5. Metabolic Bone Disease - p. 4377.e1 228. Chapter 746. Bone Structure, Growth, and Hormonal Regulation - p. 4377 229. Chapter 747. Hypophosphatasia - p. 4380 230. Chapter 748. Hyperphosphatasia - p. 4382.e1 231. Chapter 749. Osteoporosis - p. 4383 232. Part XXXI. Rehabilitation Medicine - p. 4385.e1 233. Chapter 750. Rehabilitation for Traumatic Brain Injury - p. 4386 234. Chapter 751. Spinal Cord Injury and Autonomic Dysreflexia Management - p. 4389 235. Chapter 752. Spasticity - p. 4394 236. Chapter 753. Birth Brachial Plexus Palsy - p. 4397 237. Chapter 754. Meningomyelocele (Spina Bifida) - p. 4400 238. Chapter 755. Upper and Lower Extremity Assistive Devices - p. 4402 239. Chapter 756. Health and Wellness for Children with Disabilities - p. 4404 240. Part XXXII. Environmental Health - p. 4408.e1 241. Chapter 757. Overview of Environmental Health and Children - p. 4409 242. Chapter 758. Biologic Effects of Ionizing Radiation on Children - p. 4413 243. Chapter 759. Chemical Pollutants - p. 4422 244. Chapter 760. Heavy Metal Intoxication - p. 4431 245. Chapter 761. Lead Poisoning - p. 4436 246. Chapter 762. Nonbacterial Food Poisoning - p. 4441 247. Chapter 763. Biological and Chemical Terrorism - p. 4446 248. Chapter 764. Mass Psychogenic Illness - p. 4456 249. Chapter 765. Animal and Human Bites - p. 4457 250. Chapter 766. Rat Bite Fever - p. 4460 251. Chapter 767. Mpox (Monkeypox) - p. 4461 252. Chapter 768. Envenomations - p. 4466 253. Part XXXIII. Laboratory Medicine (available in digital format only) - p. 4472.e1 254. Chapter 769. Laboratory Testing in Infants and Children - p. 4472.e2 255. Chapter 770. Reference Intervals for Laboratory Tests and Procedures - p. 4472.e7 256. Index - p. I-2
Covering every aspect of general pediatric practice, as well as details for many pediatric subspecialists, Nelson Textbook of Pediatrics, 22nd Edition, brings you fully up to date with everything from rapidly changing diagnostic and treatment protocols to new technologies to the wide range of biologic, psychologic, and social problems faced by children today. Edited and written by experts and prominent members of the pediatric medical community, this comprehensive two-volume reference covers both the science and art of pediatric practice. It remains the reference of choice among pediatricians, pediatric residents, and others involved in the care of young patients, delivering the information you need in a concise, easy-to-use format for everyday reference and study.
1. Chapter 557. Introduction to Glomerular Diseases - p. 3180 2. Section 2. Conditions Particularly Associated With Hematuria - p. 3183.e1 3. Chapter 558. Clinical Evaluation of the Child with Hematuria - p. 3184 4. Chapter 559. Isolated Glomerular Diseases Associated with Recurrent Gross Hematuria - p. 3187 5. Chapter 560. Multisystem Disease Associated with Hematuria - p. 3196 6. Chapter 561. Tubulointerstitial Disease Associated with Hematuria - p. 3205 7. Chapter 562. Vascular Diseases Associated with Hematuria - p. 3211 8. Chapter 563. Anatomic Abnormalities Associated with Hematuria - p. 3213 9. Chapter 564. Lower Urinary Tract Causes of Hematuria - p. 3217.e2 10. Section 3. Conditions Particularly Associated With Proteinuria - p. 3218.e2 11. Chapter 565. Clinical Evaluation of the Child with Proteinuria - p. 3218 12. Chapter 566. Conditions Associated with Proteinuria - p. 3220 13. Chapter 567. Nephrotic Syndrome - p. 3222 14. Section 4. Tubular Disorders - p. 3232.e2 15. Chapter 568. Tubular Function - p. 3233 16. Chapter 569. Renal Tubular Acidosis - p. 3234 17. Chapter 570. Nephrogenic Diabetes Insipidus - p. 3238 18. Chapter 571. Inherited Tubular Transport Abnormalities - p. 3240 19. Chapter 572. Renal Failure - p. 3242 20. Chapter 573. Renal Transplantation - p. 3253 21. Part XXII. Urologic Disorders in Infants and Children - p. 3259.e1 22. Chapter 574. Congenital Anomalies and Dysgenesis of the Kidneys - p. 3260 23. Chapter 575. Urinary Tract Infections - p. 3263 24. Chapter 576. Vesicoureteral Reflux - p. 3270 25. Chapter 577. Obstruction of the Urinary Tract - p. 3275 26. Chapter 578. Anomalies of the Bladder - p. 3285 27. Chapter 579. Neuropathic Bladder - p. 3288 28. Chapter 580. Enuresis and Voiding Dysfunction - p. 3291 29. Chapter 581. Anomalies of the Penis and Urethra - p. 3296 30. Chapter 582. Disorders and Anomalies of the Scrotal Contents - p. 3302 31. Chapter 583. Trauma to the Genitourinary Tract - p. 3309 32. Chapter 584. Urinary Lithiasis - p. 3311 33. Part XXIII. Gynecologic Problems of Childhood - p. 3316.e1 34. Chapter 585. Gynecologic History and Physical Examination - p. 3317 35. Chapter 586. Vulvovaginitis - p. 3320 36. Chapter 587. Vaginal Bleeding in the Prepubertal Child - p. 3326 37. Chapter 588. Breast Health - p. 3328 38. Chapter 589. Polycystic Ovary Syndrome and Hirsutism - p. 3334 39. Chapter 590. Gynecologic Neoplasms and Prevention Methods for Human Papillomavirus Infections in Adolescents - p. 3338 40. Chapter 591. Vulvovaginal and Müllerian Anomalies - p. 3347 41. Chapter 592. Gynecologic Care for Adolescents with Special Needs - p. 3355 42. Chapter 593. Female Genital Mutilation - p. 3357 43. The Endocrine System - p. 3358.e1 44. Section 1. Disorders of the Hypothalamus and Pituitary Gland - p. 3358.e1 45. Chapter 594. Hormones of the Hypothalamus and Pituitary - p. 3359 46. Chapter 595. Hypopituitarism - p. 3364 47. Chapter 596. Diabetes Insipidus - p. 3372 48. Chapter 597. Other Abnormalities of Arginine Vasopressin Metabolism and Action - p. 3375 49. Chapter 598. Hyperpituitarism - p. 3378 50. Chapter 599. Physiology of Puberty - p. 3385 51. Chapter 600. Disorders of Pubertal Development - p. 3386 52. Section 2. Disorders of the Thyroid Gland - p. 3399.e1 53. Chapter 601. Thyroid Development and Physiology - p. 3400 54. Chapter 602. Disorders of Thyroxine-Binding Globulin - p. 3400 55. Chapter 603. Hypothyroidism - p. 3402 56. Chapter 604. Thyroiditis - p. 3411 57. Chapter 605. Goiter - p. 3413 58. Chapter 606. Thyrotoxicosis - p. 3416 59. Chapter 607. Carcinoma of the Thyroid - p. 3422 60. Chapter 608. Autoimmune Polyglandular Syndromes - p. 3425 61. Chapter 609. Multiple Endocrine Neoplasia Syndromes - p. 3431 62. Section 3. Disorders of the Parathyroid Gland - p. 3432.e1 63. Chapter 610. Hormones and Peptides of Calcium Homeostasis and Bone Metabolism - p. 3433 64. Chapter 611. Hypoparathyroidism - p. 3434 65. Chapter 612. Pseudohypoparathyroidism - p. 3439 66. Chapter 613. Hyperparathyroidism - p. 3440 67. Section 4. Disorders of the Adrenal Gland - p. 3443.e1 68. Chapter 614. Physiology of the Adrenal Gland - p. 3444 69. Chapter 615. Adrenocortical Insufficiency and Altered Sensitivity to Corticosteroids - p. 3450 70. Chapter 616. Congenital Adrenal Hyperplasia and Related Disorders - p. 3462 71. Chapter 617. Adrenocortical Tumors and Masses - p. 3472 72. Chapter 618. Virilizing and Feminizing Adrenal Tumors - p. 3474.e1 73. Chapter 619. Cushing Syndrome - p. 3475 74. Chapter 620. Primary Aldosteronism - p. 3478 75. Chapter 621. Pheochromocytoma - p. 3480 76. Section 5. Disorders of the Gonads - p. 3480 77. Chapter 622. Development and Function of the Gonads - p. 3481 78. Chapter 623. Hypofunction of the Testes - p. 3487 79. Chapter 624. Pseudoprecocity Resulting from Tumors of the Testes - p. 3494 80. Chapter 625. Gynecomastia - p. 3495 81. Chapter 626. Hypofunction of the Ovaries - p. 3496 82. Chapter 627. Pseudoprecocity Resulting from Lesions of the Ovary - p. 3502 83. Chapter 628. Disorders of Sex Development - p. 3503 84. Section 6. Diabetes Mellitus in Children - p. 3513 85. Chapter 629. Diabetes Mellitus - p. 3515 86. 629.1. Classification of Diabetes Mellitus - p. 3515 87. 629.2. Type 1 Diabetes Mellitus (Immune Mediated) - p. 3517 88. 629.3. Type 2 Diabetes Mellitus - p. 3538 89. 629.4. Other Specific Types of Diabetes - p. 3542 90. Part XXV. The Nervous System - p. 3549.e4 91. Chapter 630. Neurologic Evaluation - p. 3550 92. Chapter 631. Congenital Anomalies of the Central Nervous System - p. 3561 93. Chapter 632. Deformational Plagiocephaly - p. 3584 94. Chapter 633. Seizures in Childhood - p. 3588 95. EVALUATION OF THE FIRST SEIZURE - p. 3589 96. 633.1. Febrile Seizures - p. 3595 97. 633.2. Unprovoked Seizures - p. 3597 98. 633.3. Focal Seizures and Related Epilepsy Syndromes - p. 3599 99. 633.4. Generalized Seizures and Related Epilepsy Syndromes - p. 3600 100. 633.5. Mechanisms of Seizures - p. 3603 101. 633.6. Treatment of Seizures and Epilepsy - p. 3604 102. 633.7. Neonatal Seizures - p. 3616 103. 633.8. Status Epilepticus - p. 3623 104. 633.9. Reflex Seizures (Stimulus-Precipitated Seizures) - p. 3629 105. 633.10. Nodding Syndrome - p. 3629 106. Chapter 634. Conditions That Mimic Seizures - p. 3631 107. Chapter 635. Headaches - p. 3639 108. Chapter 636. Neurocutaneous Syndromes - p. 3652 109. Chapter 637. Movement Disorders - p. 3664 110. Chapter 638. Encephalopathies - p. 3688 111. Chapter 639. Neurodegenerative Disorders of Childhood - p. 3711 112. Chapter 640. Demyelinating Disorders of the Central Nervous System - p. 3723 113. Chapter 641. Pediatric Stroke - p. 3742 114. Chapter 642. Central Nervous System Vasculitis - p. 3754 115. Chapter 643. Central Nervous System Infections - p. 3758 116. Chapter 644. Brain Abscess - p. 3779 117. Chapter 645. Idiopathic Intracranial Hypertension (Pseudotumor Cerebri) - p. 3782 118. Chapter 646. Spinal Cord Disorders - p. 3785 119. Part XXVI. Neuromuscular Disorders - p. 3790.e2 120. Chapter 647. Evaluation and Investigation of Neuromuscular Disorders - p. 3791 121. Chapter 648. Developmental Disorders of Muscle - p. 3805 122. Chapter 649. Muscular Dystrophies - p. 3828 123. Chapter 650. Endocrine and Toxic Myopathies - p. 3846 124. Chapter 651. Metabolic Myopathies and Channelopathies - p. 3848 125. Chapter 652. Disorders of Neuromuscular Transmission and of Motor Neurons - p. 3858 126. Chapter 653. Hereditary Motor-Sensory Neuropathies - p. 3876 127. Chapter 654. Toxic Neuropathies - p. 3892 128. Chapter 655. Autonomic Neuropathies - p. 3896 129. Chapter 656. Guillain-Barré Syndrome - p. 3900 130. Chapter 657. Bell Palsy - p. 3907 131. Part XXVII. Disorders of the Eye - p. 3908.e1 132. Chapter 658. Growth and Development of the Eye - p. 3908.e1 133. Chapter 659. Examination of the Eye - p. 3909 134. Chapter 660. Abnormalities of Refraction and Accommodation - p. 3912 135. Chapter 661. Disorders of Vision - p. 3915 136. Chapter 662. Abnormalities of Pupil and Iris - p. 3920 137. Chapter 663. Disorders of Eye Movement and Alignment - p. 3925 138. Chapter 664. Abnormalities of the Lids - p. 3933 139. Chapter 665. Disorders of the Lacrimal System - p. 3936 140. Chapter 666. Disorders of the Conjunctiva - p. 3939 141. Chapter 667. Abnormalities of the Cornea - p. 3943 142. Chapter 668. Abnormalities of the Lens - p. 3949 143. Chapter 669. Disorders of the Uveal Tract - p. 3952 144. Chapter 670. Disorders of the Retina and Vitreous - p. 3955 145. Chapter 671. Abnormalities of the Optic Nerve - p. 3963 146. Chapter 672. Childhood Glaucoma - p. 3968 147. Chapter 673. Orbital Abnormalities - p. 3971 148. Chapter 674. Orbital Infections - p. 3973 149. Chapter 675. Injuries to the Eye - p. 3976 150. Part XXVIII. The Ear - p. 3980.e1 151. Chapter 676. General Considerations and Evaluation of the Ear - p. 3981 152. Chapter 677. Hearing Loss - p. 3983 153. Chapter 678. Congenital Malformations of the Ear - p. 3995 154. Chapter 679. External Otitis (Otitis Externa) - p. 3999 155. Chapter 680. Otitis Media - p. 4003 156. Chapter 681. Acute Mastoiditis - p. 4016 157. Chapter 682. The Inner Ear and Diseases of the Bony Labyrinth - p. 4020 158. Chapter 683. Traumatic Injuries of the Ear and Temporal Bone - p. 4021 159. Chapter 684. Tumors of the Ear and Temporal Bone - p. 4023 160. Part XXIX. The Skin - p. 4024.e1 161. Chapter 685. Morphology of the Skin - p. 4025 162. Chapter 686. Dermatologic Evaluation of the Patient - p. 4027 163. Chapter 687. Principles of Dermatologic Therapy - p. 4038 164. Chapter 688. Dermatologic Diseases of the Neonate - p. 4041 165. Chapter 689. Cutaneous Defects - p. 4043 166. Chapter 690. Ectodermal Dysplasias - p. 4046 167. Chapter 691. Vascular Anomalies - p. 4050 168. Chapter 692. Cutaneous Nevi - p. 4061 169. Chapter 693. Hyperpigmented Lesions - p. 4067 170. Chapter 694. Hypopigmented Lesions - p. 4071 171. Chapter 695. Vesiculobullous Disorders - p. 4076 172. Chapter 696. Eczematous Disorders - p. 4087 173. Chapter 697. Photosensitivity - p. 4093 174. Chapter 698. Diseases of the Epidermis - p. 4098 175. Chapter 699. Disorders of Keratinization - p. 4110 176. Chapter 700. Diseases of the Dermis - p. 4119 177. Chapter 701. Diseases of Subcutaneous Tissue - p. 4129 178. Chapter 702. Disorders of the Sweat Glands - p. 4134 179. Chapter 703. Disorders of Hair - p. 4137 180. Chapter 704. Disorders of the Nails - p. 4142 181. Chapter 705. Disorders of the Mucous Membranes - p. 4147 182. Chapter 706. Cutaneous Bacterial Infections - p. 4150 183. Chapter 707. Cutaneous Fungal Infections - p. 4159 184. Chapter 708. Cutaneous Viral Infections - p. 4166 185. Chapter 709. Arthropod Bites and Infestations - p. 4170 186. Chapter 710. Acne - p. 4177 187. Chapter 711. Tumors of the Skin - p. 4185 188. Chapter 712. Nutritional Dermatoses - p. 4189 189. Bone and Joint Disorders - p. 4192.e1 190. Section 1. Orthopedic Problems - p. 4192.e1 191. Chapter 713. Orthopedic Growth and Development - p. 4193 192. Chapter 714. Orthopedic Evaluation of the Child - p. 4195 193. Chapter 715. The Foot and Toes - p. 4201 194. Chapter 716. Torsional and Angular Deformities of the Limb - p. 4212 195. Chapter 717. Leg-Length Discrepancy - p. 4219 196. Chapter 718. The Knee - p. 4224 197. Chapter 719. The Hip - p. 4231 198. Chapter 720. The Spine - p. 4242 199. Chapter 721. The Neck - p. 4258 200. Chapter 722. The Upper Limb - p. 4263 201. Chapter 723. Arthrogryposis - p. 4271 202. Chapter 724. Common Fractures - p. 4276 203. Chapter 725. Osteomyelitis - p. 4284 204. Chapter 726. Septic Arthritis - p. 4291 205. Section 2. Sports Medicine - p. 4294.e1 206. Chapter 727. Prevention of Injuries - p. 4294 207. Chapter 728. Management of Musculoskeletal Injury - p. 4297 208. Chapter 729. Sports-Related Traumatic Brain Injury (Concussion) - p. 4314 209. Chapter 730. Cervical Spine Injuries - p. 4318 210. Chapter 731. Heat Injuries - p. 4320 211. Chapter 732. Nutrition and Endocrine Conditions in Athletes - p. 4322 212. Chapter 733. Performance-Enhancing Aids - p. 4325 213. Chapter 734. Specific Sports and Associated Injuries - p. 4326 214. Section 3. The Skeletal Dysplasias - p. 4332.e2 215. Chapter 735. General Considerations in Skeletal Dysplasias - p. 4333 216. Chapter 736. Disorders Involving Cartilage Matrix Proteins - p. 4340 217. Chapter 737. Disorders Involving Transmembrane Receptors - p. 4345 218. Chapter 738. Disorders Involving Ion Transporters - p. 4347 219. Chapter 739. Disorders Involving Transcription Factors - p. 4349 220. Chapter 740. Osteopetrosis and Other Disorders Involving Defective Bone Resorption - p. 4350 221. Chapter 741. Other Inherited Disorders of Skeletal Development - p. 4354 222. Chapter 742. Osteogenesis Imperfecta - p. 4359 223. Section 4. Connective Tissue Disorders - p. 4363.e1 224. Chapter 743. Marfan Syndrome - p. 4363 225. Chapter 744. Ehlers-Danlos Syndrome - p. 4369 226. Chapter 745. Cutis Laxa - p. 4375 227. Section 5. Metabolic Bone Disease - p. 4377.e1 228. Chapter 746. Bone Structure, Growth, and Hormonal Regulation - p. 4377 229. Chapter 747. Hypophosphatasia - p. 4380 230. Chapter 748. Hyperphosphatasia - p. 4382.e1 231. Chapter 749. Osteoporosis - p. 4383 232. Part XXXI. Rehabilitation Medicine - p. 4385.e1 233. Chapter 750. Rehabilitation for Traumatic Brain Injury - p. 4386 234. Chapter 751. Spinal Cord Injury and Autonomic Dysreflexia Management - p. 4389 235. Chapter 752. Spasticity - p. 4394 236. Chapter 753. Birth Brachial Plexus Palsy - p. 4397 237. Chapter 754. Meningomyelocele (Spina Bifida) - p. 4400 238. Chapter 755. Upper and Lower Extremity Assistive Devices - p. 4402 239. Chapter 756. Health and Wellness for Children with Disabilities - p. 4404 240. Part XXXII. Environmental Health - p. 4408.e1 241. Chapter 757. Overview of Environmental Health and Children - p. 4409 242. Chapter 758. Biologic Effects of Ionizing Radiation on Children - p. 4413 243. Chapter 759. Chemical Pollutants - p. 4422 244. Chapter 760. Heavy Metal Intoxication - p. 4431 245. Chapter 761. Lead Poisoning - p. 4436 246. Chapter 762. Nonbacterial Food Poisoning - p. 4441 247. Chapter 763. Biological and Chemical Terrorism - p. 4446 248. Chapter 764. Mass Psychogenic Illness - p. 4456 249. Chapter 765. Animal and Human Bites - p. 4457 250. Chapter 766. Rat Bite Fever - p. 4460 251. Chapter 767. Mpox (Monkeypox) - p. 4461 252. Chapter 768. Envenomations - p. 4466 253. Part XXXIII. Laboratory Medicine (available in digital format only) - p. 4472.e1 254. Chapter 769. Laboratory Testing in Infants and Children - p. 4472.e2 255. Chapter 770. Reference Intervals for Laboratory Tests and Procedures - p. 4472.e7 256. Index - p. I-2
