Neurobiology of Infectious Diseases covers mechanisms underlying infectious diseases. It is divided into six distinct sections, beginning with the foundations of Neuroinfection. This section includes chapters on the role microbiota-gut-brain axis and specialized blood-neuronal barriers play in neurobiology of infectious diseases. The next three sections detail various bacterial infections, parasitic infections, viral infections, and fungal infections of the central nervous system. The last section reviews the proteins and other peripheral mediators that affect the central nervous system. Internationally contributed by experts in the field this book sets the foundation of neurobiology and infectious disease. Neurobiology is the study of cells of the nervous system and the organization of these cells into functional circuits that process information and mediate behavior. Current research is vital for determining pharmaceutical and medicinal treatments for neurological disorders, psychiatric disorders and diseases.
1. Cover image - p. Cover 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Contributors - p. iii 6. Foreword - p. iii 7. List of Illustrations - p. iii 8. List of Tables - p. iii 9. Section I: Foundations of neuroinfection - p. iii 10. Chapter 1: Anatomical Organization of central nervous system (CNS) - p. iii 11. Chapter 2: The enteric nervous system's (ENS) impact on the neurobiology of infectious diseases - p. 24 12. Chapter 3: The role of the microbiota–gut–brain axis on the neurobiology of infectious diseases - p. 37 13. Chapter 4: The role and function of specialized blood–neuronal barriers: Blood–CSF, blood–retinal, blood–spinal cord, blood–labyrinth, blood–nerve barriers, and blood–brain barrier (BBB) - p. 46 14. Chapter 5: Neuroimmune interactions in the neurobiology of infectious diseases - p. 59 15. Chapter 6: The routes and mechanisms of microbial translocation to the central nervous system - p. 79 16. Section II: Bacterial infections of CNS - p. 97 17. Chapter 7: Brain infections, encephalitis and meningitis: Streptococcus pneumoniae - p. 97 18. Chapter 8: Brain infections, encephalitis, and meningitis: Neisseria meningitidis - p. 128 19. Chapter 9: Brain infection, encephalitis, and meningitis: Streptococcus agalactiae - p. 148 20. Chapter 10: Brain infections, encephalitis, and meningitis: Mycobacterium tuberculosis - p. 161 21. Chapter 11: Neurosyphilis - p. 179 22. Chapter 12: Brain infections, encephalitis, and meningitis: Lyme disease–Lyme borreliosis - p. 197 23. Chapter 13: Brain infections, encephalitis, and meningitis: Brucelosis - p. 208 24. Chapter 14: Brain infections, encephalitis, and meningitis: Listeria monocytogenes–Listeriosis - p. 219 25. Chapter 15: Sepsis-associated encephalopathy: Understanding the brain dysfunction in sepsis - p. 235 26. Section III: Parasitic infections of CNS - p. 252 27. Chapter 16: African trypanosomiasis: Comprehending the parasite pathogenesis in the brain - p. 252 28. Chapter 17: Cerebral malaria: Understanding the parasite pathogenesis in the brain - p. 278 29. Chapter 18: Neurocysticercosis - p. 299 30. Chapter 19: Free-living amoebae: Pathogens and the central nervous system (CNS) disease - p. 313 31. Chapter 20: Pathophysiological mechanisms of Toxoplasma gondii infection in the central nervous system (CNS) - p. 328 32. Section IV: Viral infections of CNS - p. 343 33. Chapter 21: HIV-infected human brain: Implications in HIV infection and immune response - p. 343 34. Chapter 22: SARS-CoV-2 and nervous system: From pathogenesis of disease to clinical manifestations - p. 356 35. Chapter 23: The neurobiology of herpes simplex virus infection - p. 367 36. Chapter 24: Zika virus: Infection of the central nervous system (CNS) - p. 382 37. Chapter 25: Dengue fever and its neurological complications - p. 393 38. Chapter 26: Japanese encephalitis - p. 415 39. Chapter 27: West Nile viruses: Infection of the central nervous system (CNS) - p. 434 40. Chapter 28: Tick-borne encephalitis (TBE) - p. 445 41. Chapter 29: Chikungunya virus: Infection of the central nervous system - p. 464 42. Section V: Fungal infections of CNS - p. 482 43. Chapter 30: Brain infections, encephalitis, and meningitis: Cryptococcus sp. - p. 482 44. Chapter 31: Central nervous system infection due to Histoplasma capsulatum - p. 493 45. Chapter 32: Brain infections, encephalitis, and meningitis: Coccidioides sp. - p. 503 46. Chapter 33: Brain infections, encephalitis, and meningitis: Candida sp. - p. 512 47. Section VI: Proteins and other peripheral mediators that affect the CNS - p. 524 48. Chapter 34: Overview of human transmissible spongiform encephalopathies - p. 524 49. Chapter 35: Prion-like proteins in health and disease - p. 537 50. Chapter 36: Autoimmune encephalitis - p. 552 51. Chapter 37: Encephalitis: from mechanisms to management - p. 571 52. Index - p. 587
Neurobiology of Infectious Diseases covers mechanisms underlying infectious diseases. It is divided into six distinct sections, beginning with the foundations of Neuroinfection. This section includes chapters on the role microbiota-gut-brain axis and specialized blood-neuronal barriers play in neurobiology of infectious diseases. The next three sections detail various bacterial infections, parasitic infections, viral infections, and fungal infections of the central nervous system. The last section reviews the proteins and other peripheral mediators that affect the central nervous system. Internationally contributed by experts in the field this book sets the foundation of neurobiology and infectious disease. Neurobiology is the study of cells of the nervous system and the organization of these cells into functional circuits that process information and mediate behavior. Current research is vital for determining pharmaceutical and medicinal treatments for neurological disorders, psychiatric disorders and diseases.
1. Cover image - p. Cover 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Contributors - p. iii 6. Foreword - p. iii 7. List of Illustrations - p. iii 8. List of Tables - p. iii 9. Section I: Foundations of neuroinfection - p. iii 10. Chapter 1: Anatomical Organization of central nervous system (CNS) - p. iii 11. Chapter 2: The enteric nervous system's (ENS) impact on the neurobiology of infectious diseases - p. 24 12. Chapter 3: The role of the microbiota–gut–brain axis on the neurobiology of infectious diseases - p. 37 13. Chapter 4: The role and function of specialized blood–neuronal barriers: Blood–CSF, blood–retinal, blood–spinal cord, blood–labyrinth, blood–nerve barriers, and blood–brain barrier (BBB) - p. 46 14. Chapter 5: Neuroimmune interactions in the neurobiology of infectious diseases - p. 59 15. Chapter 6: The routes and mechanisms of microbial translocation to the central nervous system - p. 79 16. Section II: Bacterial infections of CNS - p. 97 17. Chapter 7: Brain infections, encephalitis and meningitis: Streptococcus pneumoniae - p. 97 18. Chapter 8: Brain infections, encephalitis, and meningitis: Neisseria meningitidis - p. 128 19. Chapter 9: Brain infection, encephalitis, and meningitis: Streptococcus agalactiae - p. 148 20. Chapter 10: Brain infections, encephalitis, and meningitis: Mycobacterium tuberculosis - p. 161 21. Chapter 11: Neurosyphilis - p. 179 22. Chapter 12: Brain infections, encephalitis, and meningitis: Lyme disease–Lyme borreliosis - p. 197 23. Chapter 13: Brain infections, encephalitis, and meningitis: Brucelosis - p. 208 24. Chapter 14: Brain infections, encephalitis, and meningitis: Listeria monocytogenes–Listeriosis - p. 219 25. Chapter 15: Sepsis-associated encephalopathy: Understanding the brain dysfunction in sepsis - p. 235 26. Section III: Parasitic infections of CNS - p. 252 27. Chapter 16: African trypanosomiasis: Comprehending the parasite pathogenesis in the brain - p. 252 28. Chapter 17: Cerebral malaria: Understanding the parasite pathogenesis in the brain - p. 278 29. Chapter 18: Neurocysticercosis - p. 299 30. Chapter 19: Free-living amoebae: Pathogens and the central nervous system (CNS) disease - p. 313 31. Chapter 20: Pathophysiological mechanisms of Toxoplasma gondii infection in the central nervous system (CNS) - p. 328 32. Section IV: Viral infections of CNS - p. 343 33. Chapter 21: HIV-infected human brain: Implications in HIV infection and immune response - p. 343 34. Chapter 22: SARS-CoV-2 and nervous system: From pathogenesis of disease to clinical manifestations - p. 356 35. Chapter 23: The neurobiology of herpes simplex virus infection - p. 367 36. Chapter 24: Zika virus: Infection of the central nervous system (CNS) - p. 382 37. Chapter 25: Dengue fever and its neurological complications - p. 393 38. Chapter 26: Japanese encephalitis - p. 415 39. Chapter 27: West Nile viruses: Infection of the central nervous system (CNS) - p. 434 40. Chapter 28: Tick-borne encephalitis (TBE) - p. 445 41. Chapter 29: Chikungunya virus: Infection of the central nervous system - p. 464 42. Section V: Fungal infections of CNS - p. 482 43. Chapter 30: Brain infections, encephalitis, and meningitis: Cryptococcus sp. - p. 482 44. Chapter 31: Central nervous system infection due to Histoplasma capsulatum - p. 493 45. Chapter 32: Brain infections, encephalitis, and meningitis: Coccidioides sp. - p. 503 46. Chapter 33: Brain infections, encephalitis, and meningitis: Candida sp. - p. 512 47. Section VI: Proteins and other peripheral mediators that affect the CNS - p. 524 48. Chapter 34: Overview of human transmissible spongiform encephalopathies - p. 524 49. Chapter 35: Prion-like proteins in health and disease - p. 537 50. Chapter 36: Autoimmune encephalitis - p. 552 51. Chapter 37: Encephalitis: from mechanisms to management - p. 571 52. Index - p. 587
