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Ideal for neurologists and other health care professionals who treat patients with neuromuscular diseases, Neuromuscular Case Studies, 2nd Edition, presents more than 100 cases of both common and rare neuromuscular disorders. Dr. Tulio E. Bertorini provides the latest tools and strategies for diagnosis and management that minimize disability and maximize quality of life for your patients, including up-to-date coverage of numerous recent advances in the field. Using a multidisciplinary approach, this practical text contains two parts: the first includes basic aspects of anatomy, physiology, diagnostic tests, and therapeutic strategies; the second describes specific cases and their diagnosis and management.

1. Introduction - p. 1 2. 1. Neuromuscular Anatomy and Function - p. 2 3. 2. Neurologic Evaluation and Ancillary Tests - p. 26 4. 3. Therapy in Neuromuscular Diseases - p. 74 5. Case Studies - p. 95 6. Case 1. An Elderly Woman With Numbness in the Hands - p. 96 7. Case 2. A Diabetic Man With Arm Swelling, Pain, and Numbness - p. 98 8. Case 3. A Diabetic Man With Hand Numbness and Fainting Spells - p. 105 9. Case 4. A Man With Hand Pain - p. 109 10. Case 5. A Woman With Hand Weakness, Numbness, and Pain After Cardiac Catheterization - p. 114 11. Case 6. A Man Who Practices Karate and Has Forearm Pain - p. 116 12. Case 7. A Man With a History of Polio Who Developed Hand Weakness and Numbness - p. 120 13. Case 8. A Young Woman With Multiple Sclerosis and Hand Numbness - p. 126 14. Case 9. A Woman With a Wrist Drop and a Mass in the Arm - p. 130 15. Case 10. A Man With Bilateral Arm Weakness After Lumbar Surgery - p. 135 16. Case 11. A Woman With Acute Onset of Shoulder Pain and Weakness - p. 140 17. Case 12. A Man With Lymphoma and Numbness in the Fingers of One Hand - p. 144 18. Case 13. A Woman With Arm Weakness After Treatment for Breast Cancer - p. 148 19. Case 14. A Diabetic Man With Shoulder Pain and Weakness - p. 151 20. Case 15. A Woman With Arm Weakness and a Skin Rash - p. 155 21. Case 16. A Woman With Neck and Arm Pain - p. 158 22. Case 17. A Woman With Neck Pain and a Weak Arm - p. 160 23. Case 18. A Woman With Back Pain and Leg Weakness - p. 164 24. Case 19. A Woman With Back Pain and Weakness - p. 168 25. Case 20. A Woman With Back Pain and Unusual Nerve Conduction Tests - p. 170 26. Case 21. A Man With Pheochromocytoma and Back Pain - p. 175 27. Case 22. A Diabetic Man With Back and Leg Pain - p. 178 28. Case 23. A Man With Leg Pain While Walking - p. 181 29. Case 24. A Man With Foot Pain - p. 185 30. Case 25. A Man With Unilateral Proximal Leg Weakness After Heart Catheterization - p. 189 31. Case 26. A Woman With Uterine Cancer and Unilateral Leg Weakness - p. 193 32. Case 27. A Man With Burning Sensations in the Thigh - p. 197 33. Case 28. A Man With Weakness and Fasciculations in the Lower Extremities - p. 200 34. Case 29. A Woman With Unilateral Facial Weakness - p. 203 35. Case 30. A Diabetic Woman With Muscle Weakness and Ophthalmoplegia - p. 207 36. Case 31. A Man With a Dropped Head - p. 212 37. Case 32. A Man in the “Barrel” - p. 219 38. Case 33A. A Man With a Long History of Muscle Weakness in One Arm - p. 223 39. Case 33B. A Young Man With Longstanding Weakness in Both Arms - p. 226 40. Case 34. A Man With Progressive Leg Muscle Weakness 20 Years After an Acute Paralysis - p. 230 41. Case 35. A Man With One Large Calf - p. 234 42. Case 36. A Man With Muscle Spasms and Elevated Serum Creatine Kinase - p. 239 43. Case 37. A Man With Muscle Twitching and Poor Balance - p. 244 44. Case 38. A Floppy Child - p. 250 45. Case 39. A Man With Acute Areflexic Paralysis and Central Nervous System Symptoms - p. 257 46. Case 40. A Man With Acute Muscle Weakness and Respiratory Failure - p. 263 47. Case 41. A Young Woman With Acute Onset of Clumsiness and Ophthalmoplegia - p. 268 48. Case 42. A Woman With Seafood Poisoning in Catfish Country - p. 272 49. Case 43. A Woman With a Kingly Disease - p. 276 50. Case 44. A Myasthenic Woman With Persistent Weakness - p. 283 51. Case 45. A Woman With COVID-19 Infection and Quadriparesis - p. 288 52. Case 46. A Man With Neck Pain and Numbness in the Hands - p. 291 53. Case 47. A Woman With Peripheral Neuropathy and Frequent Falls - p. 293 54. Case 48. A Woman With Progressive Four Limb Paresthesias - p. 298 55. Case 49. An Elderly Woman With Frequent Falls and Abnormal MRI - p. 301 56. Case 50. A Man With Weakness in the Legs - p. 303 57. Case 51. An Elderly Woman With Asymmetric Weakness and a Monoclonal Gammopathy - p. 306 58. Case 52. A Man With Progressive Weakness and Fasciculations - p. 309 59. Case 53. A Man With Diabetic Polyneuropathy Who Developed Rapidly Progressive Weakness - p. 320 60. Case 54A. An Older Man With Leg Numbness - p. 325 61. Case 54B. An Elderly Man With a Peripheral Neuropathy Like His Sister - p. 329 62. Case 55. A Man With Progressive Lower Extremity Weakness and Monoclonal Gammopathy - p. 333 63. Case 56. A Woman With a Neuropathy and Symptoms of a Central Nervous System Disease - p. 340 64. Case 57. A Man With Progressive Weakness After a Gastroplasty - p. 344 65. Case 58. A Diabetic Woman With Unilateral Proximal Leg Weakness and Pain - p. 348 66. Case 59. A Diabetic Man With Bilateral Arm Weakness - p. 352 67. Case 60. A Diabetic Man With Acute Onset of Pain and Swelling in the Thigh - p. 356 68. Case 61. A Uremic Man With Burning Feet - p. 358 69. Case 62A. A Woman With Leg Numbness, Pain, Weakness, and Slow Nerve Conduction Velocities - p. 362 70. Case 62B. A Boy With Leg Weakness - p. 365 71. Case 63. A Man With Hand Weakness and Numbness After Skiing - p. 374 72. Case 64. A Man With Recurrent Foot Drop - p. 376 73. Case 65. An Elderly Woman With Foot Drop and Hand Weakness - p. 382 74. Case 66. A Woman With Rheumatoid Arthritis Who Developed Numbness and Pain in the Feet - p. 387 75. Case 67. A Woman With Granulomatous Lesions in the Lungs and a Peripheral Neuropathy - p. 392 76. Case 68. A Man With a Neuropathy, Weight Loss, and Lung Nodules - p. 397 77. Case 69. A Woman With Difficulty Walking and Ataxia - p. 401 78. Case 70A. A Man With Progressive Neuropathy and Congestive Heart Failure - p. 407 79. Case 70B. A Woman With a Demyelinating and Axonal Neuropathy - p. 412 80. Case 71. An Elderly Woman With a Progressive Neuropathy - p. 415 81. Case 72A. A Young Woman With Difficulty Swallowing - p. 418 82. Case 72B. A Young Woman With Intermittent Weakness and a Positive Family History of Similar Problems - p. 421 83. Case 73. A Weak Woman With a Weak Baby - p. 428 84. Case 74. A Woman With Muscle Weakness and Areflexia - p. 430 85. Case 75. An Elderly Woman With Proximal Weakness - p. 433 86. Case 76. An Elderly Woman With Ptosis, Areflexia, and Weakness - p. 438 87. Case 77. A Young Woman With Distal Upper Extremity Weakness - p. 441 88. Case78. A Young Man With Episodic Weakness - p. 450 89. Case 79. An African American Man With Hyperthyroidism and Acute Paralysis - p. 455 90. Case 80. A Boy With Large Muscles, Leg Pain, and Elevated Serum Creatine Kinase - p. 457 91. Case 81. A Woman With Proximal Muscle Weakness, Calf Hypertrophy, Heel Contractures, and Elevated Serum Creatine Kinase - p. 465 92. Case 82. A Young Man With Distal Leg Wasting and Normal Sensation - p. 469 93. Case 83. A Boy With Proximal Weakness and Cardiomyopathy - p. 476 94. Case 84. A Woman With Droopy Eyelids and Difficulty Swallowing - p. 483 95. Case 85. A Man With Facial and Shoulder Muscle Weakness - p. 486 96. Case 86. A Boy Born Floppy With Severe Weakness and, Later, Contractures - p. 491 97. Case 87. A Woman With Long-standing Weakness and Foot Deformities - p. 498 98. Case 88 - p. 502 99. Case 89. A Woman With Droopy Eyelids and Ophthalmoplegia - p. 507 100. Case 90. A Man With Weakness and Swelling in the Neck - p. 513 101. Case 91. A Woman With Muscle Pains and Dark Urine - p. 517 102. Case 92. A Woman With Progressive Proximal Muscle Weakness - p. 523 103. Case 93. A Sedentary Man With Acute Respiratory Failure and Myoglobinuria - p. 529 104. Case 94. An Elderly Man With New Onset Weakness - p. 534 105. Case 95. A Uremic Man With Proximal Muscle Weakness - p. 538 106. Case 96. A Woman With Weakness, Elevated Cholesterol, and Serum Creatine Kinase Levels - p. 542 107. Case 97. An Older Woman With Leg Weakness and Atrophic Muscle Fibers on Biopsy - p. 545 108. Case 98A. A Woman With Muscle Weakness and a Skin Rash - p. 550 109. Case 98B. A Child With Muscle Weakness and a Skin Rash - p. 553 110. Case 99. A Man With Muscle Pains - p. 558 111. Case 100A. An Older Woman With Progressive Muscle Weakness - p. 562 112. Case 100B. An Elderly Man With Weakness Diagnosed as Having a Myopathy and a Neuropathy - p. 567 113. Case 101. An HIV-Infected Man With Muscle Weakness and Spasms - p. 570 114. Case 102. A Patient With Rapidly Progressive Muscle Weakness and Rather Elevated Creatine Kinase - p. 574 115. Case 103. A Woman With Painful and Swollen Legs - p. 577 116. Case 104. A Man With a Bent Spine - p. 580 117. Case 105. A Man With Muscle Stiffness and Later With Diplopia - p. 584 118. Case 106. A Woman With Muscle Cramps and Fasciculations - p. 590 119. Case 107. A Young Man With Large and Stiff Muscles - p. 596 120. Case 108. A Woman With Generalized Increased Insertional Activity on EMG - p. 602 121. Case 109. A Boy With Short Stature, Small Jaw, Muscle Hypertrophy, and Stiffness - p. 605 122. Case 110. An Elderly Woman With Muscle Spasms - p. 608 123. Case 111. A Woman With Proximal Muscle Weakness and Neuromuscular Irritability - p. 611 124. Case 112. A Woman With Focal Spontaneous Muscle Movements - p. 615 125. Index of Cases by Diagnosis - p. 619 126. Index - p. 623

Descripcion
Descripción

Ideal for neurologists and other health care professionals who treat patients with neuromuscular diseases, Neuromuscular Case Studies, 2nd Edition, presents more than 100 cases of both common and rare neuromuscular disorders. Dr. Tulio E. Bertorini provides the latest tools and strategies for diagnosis and management that minimize disability and maximize quality of life for your patients, including up-to-date coverage of numerous recent advances in the field. Using a multidisciplinary approach, this practical text contains two parts: the first includes basic aspects of anatomy, physiology, diagnostic tests, and therapeutic strategies; the second describes specific cases and their diagnosis and management.

1. Introduction - p. 1 2. 1. Neuromuscular Anatomy and Function - p. 2 3. 2. Neurologic Evaluation and Ancillary Tests - p. 26 4. 3. Therapy in Neuromuscular Diseases - p. 74 5. Case Studies - p. 95 6. Case 1. An Elderly Woman With Numbness in the Hands - p. 96 7. Case 2. A Diabetic Man With Arm Swelling, Pain, and Numbness - p. 98 8. Case 3. A Diabetic Man With Hand Numbness and Fainting Spells - p. 105 9. Case 4. A Man With Hand Pain - p. 109 10. Case 5. A Woman With Hand Weakness, Numbness, and Pain After Cardiac Catheterization - p. 114 11. Case 6. A Man Who Practices Karate and Has Forearm Pain - p. 116 12. Case 7. A Man With a History of Polio Who Developed Hand Weakness and Numbness - p. 120 13. Case 8. A Young Woman With Multiple Sclerosis and Hand Numbness - p. 126 14. Case 9. A Woman With a Wrist Drop and a Mass in the Arm - p. 130 15. Case 10. A Man With Bilateral Arm Weakness After Lumbar Surgery - p. 135 16. Case 11. A Woman With Acute Onset of Shoulder Pain and Weakness - p. 140 17. Case 12. A Man With Lymphoma and Numbness in the Fingers of One Hand - p. 144 18. Case 13. A Woman With Arm Weakness After Treatment for Breast Cancer - p. 148 19. Case 14. A Diabetic Man With Shoulder Pain and Weakness - p. 151 20. Case 15. A Woman With Arm Weakness and a Skin Rash - p. 155 21. Case 16. A Woman With Neck and Arm Pain - p. 158 22. Case 17. A Woman With Neck Pain and a Weak Arm - p. 160 23. Case 18. A Woman With Back Pain and Leg Weakness - p. 164 24. Case 19. A Woman With Back Pain and Weakness - p. 168 25. Case 20. A Woman With Back Pain and Unusual Nerve Conduction Tests - p. 170 26. Case 21. A Man With Pheochromocytoma and Back Pain - p. 175 27. Case 22. A Diabetic Man With Back and Leg Pain - p. 178 28. Case 23. A Man With Leg Pain While Walking - p. 181 29. Case 24. A Man With Foot Pain - p. 185 30. Case 25. A Man With Unilateral Proximal Leg Weakness After Heart Catheterization - p. 189 31. Case 26. A Woman With Uterine Cancer and Unilateral Leg Weakness - p. 193 32. Case 27. A Man With Burning Sensations in the Thigh - p. 197 33. Case 28. A Man With Weakness and Fasciculations in the Lower Extremities - p. 200 34. Case 29. A Woman With Unilateral Facial Weakness - p. 203 35. Case 30. A Diabetic Woman With Muscle Weakness and Ophthalmoplegia - p. 207 36. Case 31. A Man With a Dropped Head - p. 212 37. Case 32. A Man in the “Barrel” - p. 219 38. Case 33A. A Man With a Long History of Muscle Weakness in One Arm - p. 223 39. Case 33B. A Young Man With Longstanding Weakness in Both Arms - p. 226 40. Case 34. A Man With Progressive Leg Muscle Weakness 20 Years After an Acute Paralysis - p. 230 41. Case 35. A Man With One Large Calf - p. 234 42. Case 36. A Man With Muscle Spasms and Elevated Serum Creatine Kinase - p. 239 43. Case 37. A Man With Muscle Twitching and Poor Balance - p. 244 44. Case 38. A Floppy Child - p. 250 45. Case 39. A Man With Acute Areflexic Paralysis and Central Nervous System Symptoms - p. 257 46. Case 40. A Man With Acute Muscle Weakness and Respiratory Failure - p. 263 47. Case 41. A Young Woman With Acute Onset of Clumsiness and Ophthalmoplegia - p. 268 48. Case 42. A Woman With Seafood Poisoning in Catfish Country - p. 272 49. Case 43. A Woman With a Kingly Disease - p. 276 50. Case 44. A Myasthenic Woman With Persistent Weakness - p. 283 51. Case 45. A Woman With COVID-19 Infection and Quadriparesis - p. 288 52. Case 46. A Man With Neck Pain and Numbness in the Hands - p. 291 53. Case 47. A Woman With Peripheral Neuropathy and Frequent Falls - p. 293 54. Case 48. A Woman With Progressive Four Limb Paresthesias - p. 298 55. Case 49. An Elderly Woman With Frequent Falls and Abnormal MRI - p. 301 56. Case 50. A Man With Weakness in the Legs - p. 303 57. Case 51. An Elderly Woman With Asymmetric Weakness and a Monoclonal Gammopathy - p. 306 58. Case 52. A Man With Progressive Weakness and Fasciculations - p. 309 59. Case 53. A Man With Diabetic Polyneuropathy Who Developed Rapidly Progressive Weakness - p. 320 60. Case 54A. An Older Man With Leg Numbness - p. 325 61. Case 54B. An Elderly Man With a Peripheral Neuropathy Like His Sister - p. 329 62. Case 55. A Man With Progressive Lower Extremity Weakness and Monoclonal Gammopathy - p. 333 63. Case 56. A Woman With a Neuropathy and Symptoms of a Central Nervous System Disease - p. 340 64. Case 57. A Man With Progressive Weakness After a Gastroplasty - p. 344 65. Case 58. A Diabetic Woman With Unilateral Proximal Leg Weakness and Pain - p. 348 66. Case 59. A Diabetic Man With Bilateral Arm Weakness - p. 352 67. Case 60. A Diabetic Man With Acute Onset of Pain and Swelling in the Thigh - p. 356 68. Case 61. A Uremic Man With Burning Feet - p. 358 69. Case 62A. A Woman With Leg Numbness, Pain, Weakness, and Slow Nerve Conduction Velocities - p. 362 70. Case 62B. A Boy With Leg Weakness - p. 365 71. Case 63. A Man With Hand Weakness and Numbness After Skiing - p. 374 72. Case 64. A Man With Recurrent Foot Drop - p. 376 73. Case 65. An Elderly Woman With Foot Drop and Hand Weakness - p. 382 74. Case 66. A Woman With Rheumatoid Arthritis Who Developed Numbness and Pain in the Feet - p. 387 75. Case 67. A Woman With Granulomatous Lesions in the Lungs and a Peripheral Neuropathy - p. 392 76. Case 68. A Man With a Neuropathy, Weight Loss, and Lung Nodules - p. 397 77. Case 69. A Woman With Difficulty Walking and Ataxia - p. 401 78. Case 70A. A Man With Progressive Neuropathy and Congestive Heart Failure - p. 407 79. Case 70B. A Woman With a Demyelinating and Axonal Neuropathy - p. 412 80. Case 71. An Elderly Woman With a Progressive Neuropathy - p. 415 81. Case 72A. A Young Woman With Difficulty Swallowing - p. 418 82. Case 72B. A Young Woman With Intermittent Weakness and a Positive Family History of Similar Problems - p. 421 83. Case 73. A Weak Woman With a Weak Baby - p. 428 84. Case 74. A Woman With Muscle Weakness and Areflexia - p. 430 85. Case 75. An Elderly Woman With Proximal Weakness - p. 433 86. Case 76. An Elderly Woman With Ptosis, Areflexia, and Weakness - p. 438 87. Case 77. A Young Woman With Distal Upper Extremity Weakness - p. 441 88. Case78. A Young Man With Episodic Weakness - p. 450 89. Case 79. An African American Man With Hyperthyroidism and Acute Paralysis - p. 455 90. Case 80. A Boy With Large Muscles, Leg Pain, and Elevated Serum Creatine Kinase - p. 457 91. Case 81. A Woman With Proximal Muscle Weakness, Calf Hypertrophy, Heel Contractures, and Elevated Serum Creatine Kinase - p. 465 92. Case 82. A Young Man With Distal Leg Wasting and Normal Sensation - p. 469 93. Case 83. A Boy With Proximal Weakness and Cardiomyopathy - p. 476 94. Case 84. A Woman With Droopy Eyelids and Difficulty Swallowing - p. 483 95. Case 85. A Man With Facial and Shoulder Muscle Weakness - p. 486 96. Case 86. A Boy Born Floppy With Severe Weakness and, Later, Contractures - p. 491 97. Case 87. A Woman With Long-standing Weakness and Foot Deformities - p. 498 98. Case 88 - p. 502 99. Case 89. A Woman With Droopy Eyelids and Ophthalmoplegia - p. 507 100. Case 90. A Man With Weakness and Swelling in the Neck - p. 513 101. Case 91. A Woman With Muscle Pains and Dark Urine - p. 517 102. Case 92. A Woman With Progressive Proximal Muscle Weakness - p. 523 103. Case 93. A Sedentary Man With Acute Respiratory Failure and Myoglobinuria - p. 529 104. Case 94. An Elderly Man With New Onset Weakness - p. 534 105. Case 95. A Uremic Man With Proximal Muscle Weakness - p. 538 106. Case 96. A Woman With Weakness, Elevated Cholesterol, and Serum Creatine Kinase Levels - p. 542 107. Case 97. An Older Woman With Leg Weakness and Atrophic Muscle Fibers on Biopsy - p. 545 108. Case 98A. A Woman With Muscle Weakness and a Skin Rash - p. 550 109. Case 98B. A Child With Muscle Weakness and a Skin Rash - p. 553 110. Case 99. A Man With Muscle Pains - p. 558 111. Case 100A. An Older Woman With Progressive Muscle Weakness - p. 562 112. Case 100B. An Elderly Man With Weakness Diagnosed as Having a Myopathy and a Neuropathy - p. 567 113. Case 101. An HIV-Infected Man With Muscle Weakness and Spasms - p. 570 114. Case 102. A Patient With Rapidly Progressive Muscle Weakness and Rather Elevated Creatine Kinase - p. 574 115. Case 103. A Woman With Painful and Swollen Legs - p. 577 116. Case 104. A Man With a Bent Spine - p. 580 117. Case 105. A Man With Muscle Stiffness and Later With Diplopia - p. 584 118. Case 106. A Woman With Muscle Cramps and Fasciculations - p. 590 119. Case 107. A Young Man With Large and Stiff Muscles - p. 596 120. Case 108. A Woman With Generalized Increased Insertional Activity on EMG - p. 602 121. Case 109. A Boy With Short Stature, Small Jaw, Muscle Hypertrophy, and Stiffness - p. 605 122. Case 110. An Elderly Woman With Muscle Spasms - p. 608 123. Case 111. A Woman With Proximal Muscle Weakness and Neuromuscular Irritability - p. 611 124. Case 112. A Woman With Focal Spontaneous Muscle Movements - p. 615 125. Index of Cases by Diagnosis - p. 619 126. Index - p. 623

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