Novel Platforms for Drug Delivery Applications covers diverse aspects in the design, synthesis and characterization of novel drug delivery platforms and devices. This book comprehensively details the development, application and performance of various novel molecular frameworks as potent drug delivery vehicles. Chapters cover a range of materials and molecular platforms for drug delivery, from hydrogels, nanocarriers and metal-organic-frameworks, to ?-cyclodextrin and polyphosphazene. Each chapter discusses the benefits and limitations of each drug delivery system, as well as toxicological and safety implications. This book offers an interdisciplinary approach to this fast-moving topic, bridging the disciplines of materials science and pharmacology.
1. Chapter 1 Introduction: state of the art, new challenges, and opportunities for drug delivery and its application - p. 1 2. Chapter 2 Drug delivery application: an outlook on past and present technologies - p. 9 3. Chapter 3 General mechanisms of drug loading and sustained release - p. 31 4. Chapter 4 Supramolecular hydrogels as drug delivery systems for nerve regeneration and wound healing - p. 59 5. Chapter 5 Molecularly imprinted polymeric carriers for controlled drug release - p. 85 6. Chapter 6 Engineered extracellular vesicles as drug delivery systems for the next generation of nanomedicine - p. 105 7. Chapter 7 Polyelectrolyte multilayer films for cancer therapy - p. 129 8. Chapter 8 Porous metal–organic framework nanoscale carriers as a potential platform for drug delivery - p. 153 9. Chapter 9 Stimulus-responsive liposomes as smart nanocarriers for drug delivery applications - p. 177 10. Chapter 10 Hybrid platforms for drug delivery applications - p. 217 11. Chapter 11 Self-nanoemulsifying drug delivery systems with bioavailability potential - p. 257 12. Chapter 12 Graphene-based nanomaterials for targeted drug delivery and tissue engineering - p. 277 13. Chapter 13 Bionanocomposites as a new platform for drug delivery systems - p. 289 14. Chapter 14 Nanotube platforms for effective drug delivery applications - p. 317 15. Chapter 15 Biodegradable polymeric nanoparticle drug for oral delivery applications - p. 333 16. Chapter 16 Delivery of radiopharmaceuticals and theranostic agents: targeted alpha therapy - p. 349 17. Chapter 17 Controlled drug release and drug delivery applications from mesoporous nanoparticles - p. 405 18. Chapter 18 Porous nanostructured metal oxides as potential scaffolds for drug delivery - p. 437 19. Chapter 19 Thin films as an emerging platform for drug delivery - p. 459 20. Chapter 20 Modeling and simulation in drug delivery - p. 491 21. Chapter 21 In-vivo drug release studies - p. 537 22. Chapter 22 Toxicity measurement and toxicity studies of drug delivery - p. 553 23. Chapter 23 Nasal and pulmonary routes of drug delivery - p. 569 24. Chapter 24 “Gene therapy”: ethical and regulatory issues - p. 607 25. Chapter 25 New challenges in drug discovery - p. 619 26. Index - p. 645
Novel Platforms for Drug Delivery Applications covers diverse aspects in the design, synthesis and characterization of novel drug delivery platforms and devices. This book comprehensively details the development, application and performance of various novel molecular frameworks as potent drug delivery vehicles. Chapters cover a range of materials and molecular platforms for drug delivery, from hydrogels, nanocarriers and metal-organic-frameworks, to ?-cyclodextrin and polyphosphazene. Each chapter discusses the benefits and limitations of each drug delivery system, as well as toxicological and safety implications. This book offers an interdisciplinary approach to this fast-moving topic, bridging the disciplines of materials science and pharmacology.
1. Chapter 1 Introduction: state of the art, new challenges, and opportunities for drug delivery and its application - p. 1 2. Chapter 2 Drug delivery application: an outlook on past and present technologies - p. 9 3. Chapter 3 General mechanisms of drug loading and sustained release - p. 31 4. Chapter 4 Supramolecular hydrogels as drug delivery systems for nerve regeneration and wound healing - p. 59 5. Chapter 5 Molecularly imprinted polymeric carriers for controlled drug release - p. 85 6. Chapter 6 Engineered extracellular vesicles as drug delivery systems for the next generation of nanomedicine - p. 105 7. Chapter 7 Polyelectrolyte multilayer films for cancer therapy - p. 129 8. Chapter 8 Porous metal–organic framework nanoscale carriers as a potential platform for drug delivery - p. 153 9. Chapter 9 Stimulus-responsive liposomes as smart nanocarriers for drug delivery applications - p. 177 10. Chapter 10 Hybrid platforms for drug delivery applications - p. 217 11. Chapter 11 Self-nanoemulsifying drug delivery systems with bioavailability potential - p. 257 12. Chapter 12 Graphene-based nanomaterials for targeted drug delivery and tissue engineering - p. 277 13. Chapter 13 Bionanocomposites as a new platform for drug delivery systems - p. 289 14. Chapter 14 Nanotube platforms for effective drug delivery applications - p. 317 15. Chapter 15 Biodegradable polymeric nanoparticle drug for oral delivery applications - p. 333 16. Chapter 16 Delivery of radiopharmaceuticals and theranostic agents: targeted alpha therapy - p. 349 17. Chapter 17 Controlled drug release and drug delivery applications from mesoporous nanoparticles - p. 405 18. Chapter 18 Porous nanostructured metal oxides as potential scaffolds for drug delivery - p. 437 19. Chapter 19 Thin films as an emerging platform for drug delivery - p. 459 20. Chapter 20 Modeling and simulation in drug delivery - p. 491 21. Chapter 21 In-vivo drug release studies - p. 537 22. Chapter 22 Toxicity measurement and toxicity studies of drug delivery - p. 553 23. Chapter 23 Nasal and pulmonary routes of drug delivery - p. 569 24. Chapter 24 “Gene therapy”: ethical and regulatory issues - p. 607 25. Chapter 25 New challenges in drug discovery - p. 619 26. Index - p. 645
