A companion to the classic Adler’s Physiology of the Eye— correlating basic science and clinical management to describe the how and why of eye disease processes and the related best management protocols. Covers all major areas of ophthalmic disease, the concise chapter structure features line artworks, call-out boxes and summaries for easy navigation and understanding. This resource provides you with a better and more practical understanding of the science behind eye disease and its relation to treatment.
1. Cover image - p. Cover 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. List of Contributors - p. iii 6. Dedication - p. iii 7. Foreword - p. iii 8. Preface - p. iii 9. SECTION 1: Cornea - p. iii 10. List of Illustrations - p. iii 11. List of Tables - p. iii 12. Chapter 1: Loss of corneal transparency - p. iii 13. Chapter 2: Abnormalities of corneal wound healing - p. 8 14. Chapter 3: Wound healing after laser in situ keratomileusis and photorefractive keratectomy - p. 15 15. Chapter 4: Genetics and mechanisms of hereditary corneal dystrophies - p. 21 16. Chapter 5: Fuchs’ endothelial corneal dystrophy - p. 33 17. Chapter 6: Keratoconus - p. 41 18. Chapter 7: Infectious keratitis - p. 48 19. Chapter 8: Corneal graft rejection - p. 55 20. Chapter 9: Corneal edema - p. 63 21. Chapter 10: Corneal angiogenesis and lymphangiogenesis - p. 73 22. Chapter 11: Ocular surface restoration - p. 82 23. Chapter 12: Herpetic keratitis - p. 90 24. Chapter 13: Ocular allergy - p. 97 25. SECTION 2: Dry eye - p. 104 26. Chapter 14: The lacrimal gland and dry-eye disease - p. 104 27. Chapter 15: Immune mechanisms of dry-eye disease - p. 113 28. Chapter 16: Disruption of tear film and blink dynamics - p. 122 29. Chapter 17: Abnormalities of eyelid and tear film lipid - p. 130 30. Chapter 18: Dry eye: abnormalities of tear film mucins - p. 137 31. SECTION 3: Glaucoma - p. 145 32. Chapter 19: Steroid-induced glaucoma - p. 145 33. Chapter 20: Biomechanical changes of the optic disc - p. 152 34. Chapter 21: Pigmentary dispersion syndrome and glaucoma - p. 164 35. Chapter 22: Abnormal trabecular meshwork outflow - p. 170 36. Chapter 23: Pressure-induced optic nerve damage - p. 177 37. Chapter 24: Exfoliation (pseudoexfoliation) syndrome - p. 183 38. Chapter 25: Angle closure glaucoma - p. 192 39. Chapter 26: Central nervous system changes in glaucoma - p. 199 40. Chapter 27: Retinal ganglion cell death in glaucoma - p. 206 41. Chapter 28: Wound-healing responses to glaucoma surgery - p. 213 42. Chapter 29: Blood flow changes in glaucoma - p. 222 43. SECTION 4: Lens - p. 230 44. Chapter 30: Biochemical mechanisms of age-related cataract - p. 230 45. Chapter 31: Posterior capsule opacification - p. 237 46. Chapter 32: Diabetes-associated cataracts - p. 242 47. Chapter 33: Steroid-induced cataract - p. 249 48. Chapter 34: Presbyopia - p. 257 49. Chapter 35: Restoration of accommodation - p. 266 50. Chapter 36: Intraoperative floppy iris syndrome - p. 273 51. SECTION 5: Neuro-Ophthalmology - p. 277 52. Chapter 37: Optic neuritis - p. 277 53. Chapter 38: Abnormal ocular motor control - p. 288 54. Chapter 39: Idiopathic intracranial hypertension (idiopathic pseudotumor cerebri) - p. 297 55. Chapter 40: Giant cell arteritis - p. 305 56. Chapter 41: Ischemic optic neuropathy - p. 312 57. Chapter 42: Optic nerve axonal injury - p. 321 58. Chapter 43: Leber’s hereditary optic neuropathy - p. 329 59. Chapter 44: Optic atrophy - p. 336 60. Chapter 45: Nystagmus - p. 343 61. Chapter 46: Toxic optic nerve neuropathies - p. 356 62. SECTION 6: Oncology - p. 361 63. Chapter 47: Uveal melanoma - p. 361 64. Chapter 48: Genetics of hereditary retinoblastoma - p. 368 65. Chapter 49: Molecular basis of low-penetrance retinoblastoma - p. 376 66. Chapter 50: Vasculogenic mimicry - p. 382 67. Chapter 51: Treatment of choroidal melanoma - p. 388 68. Chapter 52: Sebaceous cell carcinoma - p. 395 69. Chapter 53: Neurofibromatosis - p. 407 70. SECTION 7: Other - p. 414 71. Chapter 54: Phthisis bulbi - p. 414 72. Chapter 55: Myopia - p. 423 73. Chapter 56: Pathogenesis of Graves’ ophthalmopathy - p. 432 74. SECTION 8: Pediatrics - p. 437 75. Chapter 57: Duane syndrome - p. 437 76. Chapter 58: Amblyopia - p. 444 77. Chapter 59: Strabismus - p. 453 78. Chapter 60: Albinism - p. 460 79. Chapter 61: Aniridia - p. 471 80. SECTION 9: Retina - p. 477 81. Chapter 62: Color vision defects - p. 477 82. Chapter 63: Acute retinal vascular occlusive disorders - p. 485 83. Chapter 64: Retinal photic injury: Laboratory and clinical findings - p. 498 84. Chapter 65: Vascular damage in diabetic retinopathy - p. 505 85. Chapter 66: Neovascularization in diabetic retinopathy - p. 513 86. Chapter 67: Diabetic macular edema - p. 518 87. Chapter 68: Dry age-related macular degeneration and age-related macular degeneration pathogenesis - p. 526 88. Chapter 69: Neovascular age-related macular degeneration - p. 535 89. Chapter 70: Inhibition of angiogenesis - p. 543 90. Chapter 71: Retinal detachment - p. 553 91. Chapter 72: Retinopathy of prematurity - p. 561 92. Chapter 73: Retinal energy metabolism - p. 571 93. Chapter 74: Retinitis pigmentosa and related disorders - p. 578 94. Chapter 75: Visual prostheses and other assistive devices - p. 589 95. Chapter 76: Paraneoplastic retinal degeneration - p. 598 96. Chapter 77: Cellular repopulation of the retina - p. 606 97. Chapter 78: Proliferative vitreoretinopathy - p. 611 98. SECTION 10: Uveitis - p. 617 99. Chapter 79: Immunologic mechanisms of uveitis - p. 617 100. Chapter 80: Herpesvirus retinitis - p. 627 101. Chapter 81: Sympathetic ophthalmia - p. 634 102. Chapter 82: Scleritis - p. 641 103. Chapter 83: Infectious uveitis - p. 653 104. Chapter 84: Ocular sarcoidosis - p. 665 105. Index - p. 671
A companion to the classic Adler’s Physiology of the Eye— correlating basic science and clinical management to describe the how and why of eye disease processes and the related best management protocols. Covers all major areas of ophthalmic disease, the concise chapter structure features line artworks, call-out boxes and summaries for easy navigation and understanding. This resource provides you with a better and more practical understanding of the science behind eye disease and its relation to treatment.
1. Cover image - p. Cover 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. List of Contributors - p. iii 6. Dedication - p. iii 7. Foreword - p. iii 8. Preface - p. iii 9. SECTION 1: Cornea - p. iii 10. List of Illustrations - p. iii 11. List of Tables - p. iii 12. Chapter 1: Loss of corneal transparency - p. iii 13. Chapter 2: Abnormalities of corneal wound healing - p. 8 14. Chapter 3: Wound healing after laser in situ keratomileusis and photorefractive keratectomy - p. 15 15. Chapter 4: Genetics and mechanisms of hereditary corneal dystrophies - p. 21 16. Chapter 5: Fuchs’ endothelial corneal dystrophy - p. 33 17. Chapter 6: Keratoconus - p. 41 18. Chapter 7: Infectious keratitis - p. 48 19. Chapter 8: Corneal graft rejection - p. 55 20. Chapter 9: Corneal edema - p. 63 21. Chapter 10: Corneal angiogenesis and lymphangiogenesis - p. 73 22. Chapter 11: Ocular surface restoration - p. 82 23. Chapter 12: Herpetic keratitis - p. 90 24. Chapter 13: Ocular allergy - p. 97 25. SECTION 2: Dry eye - p. 104 26. Chapter 14: The lacrimal gland and dry-eye disease - p. 104 27. Chapter 15: Immune mechanisms of dry-eye disease - p. 113 28. Chapter 16: Disruption of tear film and blink dynamics - p. 122 29. Chapter 17: Abnormalities of eyelid and tear film lipid - p. 130 30. Chapter 18: Dry eye: abnormalities of tear film mucins - p. 137 31. SECTION 3: Glaucoma - p. 145 32. Chapter 19: Steroid-induced glaucoma - p. 145 33. Chapter 20: Biomechanical changes of the optic disc - p. 152 34. Chapter 21: Pigmentary dispersion syndrome and glaucoma - p. 164 35. Chapter 22: Abnormal trabecular meshwork outflow - p. 170 36. Chapter 23: Pressure-induced optic nerve damage - p. 177 37. Chapter 24: Exfoliation (pseudoexfoliation) syndrome - p. 183 38. Chapter 25: Angle closure glaucoma - p. 192 39. Chapter 26: Central nervous system changes in glaucoma - p. 199 40. Chapter 27: Retinal ganglion cell death in glaucoma - p. 206 41. Chapter 28: Wound-healing responses to glaucoma surgery - p. 213 42. Chapter 29: Blood flow changes in glaucoma - p. 222 43. SECTION 4: Lens - p. 230 44. Chapter 30: Biochemical mechanisms of age-related cataract - p. 230 45. Chapter 31: Posterior capsule opacification - p. 237 46. Chapter 32: Diabetes-associated cataracts - p. 242 47. Chapter 33: Steroid-induced cataract - p. 249 48. Chapter 34: Presbyopia - p. 257 49. Chapter 35: Restoration of accommodation - p. 266 50. Chapter 36: Intraoperative floppy iris syndrome - p. 273 51. SECTION 5: Neuro-Ophthalmology - p. 277 52. Chapter 37: Optic neuritis - p. 277 53. Chapter 38: Abnormal ocular motor control - p. 288 54. Chapter 39: Idiopathic intracranial hypertension (idiopathic pseudotumor cerebri) - p. 297 55. Chapter 40: Giant cell arteritis - p. 305 56. Chapter 41: Ischemic optic neuropathy - p. 312 57. Chapter 42: Optic nerve axonal injury - p. 321 58. Chapter 43: Leber’s hereditary optic neuropathy - p. 329 59. Chapter 44: Optic atrophy - p. 336 60. Chapter 45: Nystagmus - p. 343 61. Chapter 46: Toxic optic nerve neuropathies - p. 356 62. SECTION 6: Oncology - p. 361 63. Chapter 47: Uveal melanoma - p. 361 64. Chapter 48: Genetics of hereditary retinoblastoma - p. 368 65. Chapter 49: Molecular basis of low-penetrance retinoblastoma - p. 376 66. Chapter 50: Vasculogenic mimicry - p. 382 67. Chapter 51: Treatment of choroidal melanoma - p. 388 68. Chapter 52: Sebaceous cell carcinoma - p. 395 69. Chapter 53: Neurofibromatosis - p. 407 70. SECTION 7: Other - p. 414 71. Chapter 54: Phthisis bulbi - p. 414 72. Chapter 55: Myopia - p. 423 73. Chapter 56: Pathogenesis of Graves’ ophthalmopathy - p. 432 74. SECTION 8: Pediatrics - p. 437 75. Chapter 57: Duane syndrome - p. 437 76. Chapter 58: Amblyopia - p. 444 77. Chapter 59: Strabismus - p. 453 78. Chapter 60: Albinism - p. 460 79. Chapter 61: Aniridia - p. 471 80. SECTION 9: Retina - p. 477 81. Chapter 62: Color vision defects - p. 477 82. Chapter 63: Acute retinal vascular occlusive disorders - p. 485 83. Chapter 64: Retinal photic injury: Laboratory and clinical findings - p. 498 84. Chapter 65: Vascular damage in diabetic retinopathy - p. 505 85. Chapter 66: Neovascularization in diabetic retinopathy - p. 513 86. Chapter 67: Diabetic macular edema - p. 518 87. Chapter 68: Dry age-related macular degeneration and age-related macular degeneration pathogenesis - p. 526 88. Chapter 69: Neovascular age-related macular degeneration - p. 535 89. Chapter 70: Inhibition of angiogenesis - p. 543 90. Chapter 71: Retinal detachment - p. 553 91. Chapter 72: Retinopathy of prematurity - p. 561 92. Chapter 73: Retinal energy metabolism - p. 571 93. Chapter 74: Retinitis pigmentosa and related disorders - p. 578 94. Chapter 75: Visual prostheses and other assistive devices - p. 589 95. Chapter 76: Paraneoplastic retinal degeneration - p. 598 96. Chapter 77: Cellular repopulation of the retina - p. 606 97. Chapter 78: Proliferative vitreoretinopathy - p. 611 98. SECTION 10: Uveitis - p. 617 99. Chapter 79: Immunologic mechanisms of uveitis - p. 617 100. Chapter 80: Herpesvirus retinitis - p. 627 101. Chapter 81: Sympathetic ophthalmia - p. 634 102. Chapter 82: Scleritis - p. 641 103. Chapter 83: Infectious uveitis - p. 653 104. Chapter 84: Ocular sarcoidosis - p. 665 105. Index - p. 671
