Oligodendroglioma: Clinical Presentation, Pathology, Molecular Biology, Imaging, and Treatment features the latest "cutting-edge" molecular biology, molecular therapeutics, imaging, immunotherapy, and research methods on the topic of oligodendrogliomas. The most detailed and comprehensive resource on the subject, it provides up-to-date information on clinical presentation, pathology, molecular biology, and treatment methods, including immunotherapy. This book is a critical for students, physicians and researchers in the fields of neuroscience, neuro-oncology, neurosurgery, radiation oncology, medical oncology, and others working in research or with patients.
1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. Dedication - p. v 6. Contributors - p. xv 7. Foreword - p. xix 8. Section A: Clinical presentation and quality of life - p. xx 9. Chapter 1: Clinical presentation in adults—Brain - p. xx 10. Chapter 2: Clinical presentation of spinal oligodendrogliomas - p. 9 11. Chapter 3: Oligodendrogliomas—Atypical clinical presentations - p. 21 12. Chapter 4: Clinical presentation of pediatric oligodendrogliomas - p. 37 13. Chapter 5: Seizures, oligodendrogliomas, and brain-tumor-related epilepsy - p. 41 14. Chapter 6: Living with oligodendroglioma - p. 54 15. Section B: Pathology and molecular biology - p. 75 16. Chapter 7: Origin and development of oligodendroglioma - p. 75 17. Chapter 8: Histopathology and molecular biology of oligodendrogliomas - p. 87 18. Chapter 9: The role of biomarkers in the diagnosis and treatment of oligodendrogliomas - p. 107 19. Chapter 10: Prospects of translational proteomics and protein microarrays in oligodendroglioma - p. 115 20. Chapter 11: Pathology of pediatric oligodendroglioma - p. 127 21. Section C: Neuro-imaging - p. 135 22. Chapter 12: CT imaging of oligodendroglioma - p. 135 23. Chapter 13: Routine and advanced magnetic resonance imaging of oligodendrogliomas - p. 146 24. Chapter 14: Advanced [11C]methionine and [18F]FDG positron emission tomography for diagnosis, treatment, and follow-up of oligodendrogliomas - p. 156 25. Chapter 15: Neuroimaging of pediatric oligodendrogliomas - p. 171 26. Section D: Surgical therapy - p. 180 27. Chapter 16: Oligodendrogliomas: Basic techniques in surgery - p. 180 28. Chapter 17: Oligodendrogliomas: Advanced techniques in surgery - p. 189 29. Chapter 18: Surgical management of 1p/19q co-deleted oligodendrogliomas WHO grade II and III - p. 208 30. Chapter 19: Surgical results in anaplastic oligodendroglioma (AO) and anaplastic oligoastrocytoma (AOA) - p. 218 31. Chapter 20: Surgical management of pediatric oligodendroglioma - p. 227 32. Section E: Radiation therapy - p. 242 33. Chapter 21: Basic principles of brain tumor radiotherapy - p. 242 34. Chapter 22: Standard external beam radiation therapy for oligodendroglioma - p. 262 35. Chapter 23: Stereotactic radiosurgery in the management of oligodendroglioma - p. 270 36. Chapter 24: Proton beam therapy for oligodendroglioma - p. 278 37. Chapter 25: Interstitial brachytherapy treatment for oligodendrogliomas - p. 286 38. Chapter 26: The role of radiation in pediatric oligodendrogliomas - p. 298 39. Section F: Chemotherapy and immunotherapy - p. 306 40. Chapter 27: Basic principles of brain tumor chemotherapy - p. 306 41. Chapter 28: The use of PCV chemotherapy in oligodendrogliomas - p. 330 42. Chapter 29: Temozolomide chemotherapy for oligodendroglial tumors - p. 339 43. Chapter 30: Miscellaneous chemotherapy approaches to oligodendroglial tumors - p. 351 44. Chapter 31: Molecular Therapy for Oligodendrogliomas - p. 357 45. Chapter 32: Bevacizumab for recurrent anaplastic oligodendroglial tumors - p. 366 46. Chapter 33: Pediatric oligodendroglioma - p. 377 47. Chapter 34: Immune checkpoint blockade in glioma - p. 386 48. Index - p. 397
Oligodendroglioma: Clinical Presentation, Pathology, Molecular Biology, Imaging, and Treatment features the latest "cutting-edge" molecular biology, molecular therapeutics, imaging, immunotherapy, and research methods on the topic of oligodendrogliomas. The most detailed and comprehensive resource on the subject, it provides up-to-date information on clinical presentation, pathology, molecular biology, and treatment methods, including immunotherapy. This book is a critical for students, physicians and researchers in the fields of neuroscience, neuro-oncology, neurosurgery, radiation oncology, medical oncology, and others working in research or with patients.
1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. Dedication - p. v 6. Contributors - p. xv 7. Foreword - p. xix 8. Section A: Clinical presentation and quality of life - p. xx 9. Chapter 1: Clinical presentation in adults—Brain - p. xx 10. Chapter 2: Clinical presentation of spinal oligodendrogliomas - p. 9 11. Chapter 3: Oligodendrogliomas—Atypical clinical presentations - p. 21 12. Chapter 4: Clinical presentation of pediatric oligodendrogliomas - p. 37 13. Chapter 5: Seizures, oligodendrogliomas, and brain-tumor-related epilepsy - p. 41 14. Chapter 6: Living with oligodendroglioma - p. 54 15. Section B: Pathology and molecular biology - p. 75 16. Chapter 7: Origin and development of oligodendroglioma - p. 75 17. Chapter 8: Histopathology and molecular biology of oligodendrogliomas - p. 87 18. Chapter 9: The role of biomarkers in the diagnosis and treatment of oligodendrogliomas - p. 107 19. Chapter 10: Prospects of translational proteomics and protein microarrays in oligodendroglioma - p. 115 20. Chapter 11: Pathology of pediatric oligodendroglioma - p. 127 21. Section C: Neuro-imaging - p. 135 22. Chapter 12: CT imaging of oligodendroglioma - p. 135 23. Chapter 13: Routine and advanced magnetic resonance imaging of oligodendrogliomas - p. 146 24. Chapter 14: Advanced [11C]methionine and [18F]FDG positron emission tomography for diagnosis, treatment, and follow-up of oligodendrogliomas - p. 156 25. Chapter 15: Neuroimaging of pediatric oligodendrogliomas - p. 171 26. Section D: Surgical therapy - p. 180 27. Chapter 16: Oligodendrogliomas: Basic techniques in surgery - p. 180 28. Chapter 17: Oligodendrogliomas: Advanced techniques in surgery - p. 189 29. Chapter 18: Surgical management of 1p/19q co-deleted oligodendrogliomas WHO grade II and III - p. 208 30. Chapter 19: Surgical results in anaplastic oligodendroglioma (AO) and anaplastic oligoastrocytoma (AOA) - p. 218 31. Chapter 20: Surgical management of pediatric oligodendroglioma - p. 227 32. Section E: Radiation therapy - p. 242 33. Chapter 21: Basic principles of brain tumor radiotherapy - p. 242 34. Chapter 22: Standard external beam radiation therapy for oligodendroglioma - p. 262 35. Chapter 23: Stereotactic radiosurgery in the management of oligodendroglioma - p. 270 36. Chapter 24: Proton beam therapy for oligodendroglioma - p. 278 37. Chapter 25: Interstitial brachytherapy treatment for oligodendrogliomas - p. 286 38. Chapter 26: The role of radiation in pediatric oligodendrogliomas - p. 298 39. Section F: Chemotherapy and immunotherapy - p. 306 40. Chapter 27: Basic principles of brain tumor chemotherapy - p. 306 41. Chapter 28: The use of PCV chemotherapy in oligodendrogliomas - p. 330 42. Chapter 29: Temozolomide chemotherapy for oligodendroglial tumors - p. 339 43. Chapter 30: Miscellaneous chemotherapy approaches to oligodendroglial tumors - p. 351 44. Chapter 31: Molecular Therapy for Oligodendrogliomas - p. 357 45. Chapter 32: Bevacizumab for recurrent anaplastic oligodendroglial tumors - p. 366 46. Chapter 33: Pediatric oligodendroglioma - p. 377 47. Chapter 34: Immune checkpoint blockade in glioma - p. 386 48. Index - p. 397
