Be prepared to diagnose and manage any condition you encounter in your practice! This bestselling reference gives you direct access to a complete range of full-color clinical images and patient radiographs that illustrate the differentiating characteristics of lesions in the oral and maxillofacial region. Significantly revised and updated content throughout this edition brings you the latest information on the etiology, clinical features, histopathology, treatment, and prognosis of each disease entity, as well as cutting-edge topics such as bisphosphonate osteonecrosis, the oral complications associated with methamphetamine abuse, solitary fibrous tumors, gene mutation, and plasminogen deficiency.
1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. iv 5. Dedication - p. v 6. Contributors - p. vi 7. Preface - p. vii 8. 1 Developmental Defects of the Oral and Maxillofacial Region - p. 1 9. 2 Abnormalities of Teeth - p. 49 10. Environmental Alterations of Teeth - p. 49 11. Developmental Alterations of Teeth - p. 70 12. Bibliography - p. 105 13. 3 Pulpal and Periapical Disease - p. 111 14. 4 Periodontal Diseases - p. 140 15. 5 Bacterial Infections - p. 164 16. 6 Fungal and Protozoal Diseases - p. 191 17. 7 Viral Infections - p. 218 18. 8 Physical and Chemical Injuries - p. 259 19. 9 Allergies and Immunologic Diseases - p. 303 20. 10 Epithelial Pathology - p. 331 21. ◆ Benign Epithelial Lesions Associated with Human Papillomavirus - p. 331 22. ◆ Molluscum Contagiosum - p. 340 23. ◆ Verruciform Xanthoma - p. 341 24. ◆ Seborrheic Keratosis - p. 342 25. ◆ Sebaceous Hyperplasia - p. 344 26. ◆ Ephelis (Freckle) - p. 345 27. ◆ Actinic Lentigo (Lentigo Solaris; Solar Lentigo; Age Spot; Liver Spot; Senile Lentigo) - p. 345 28. ◆ Lentigo Simplex - p. 346 29. ◆ Melasma (Mask of Pregnancy; Chloasma) - p. 347 30. ◆ Oral Melanotic Macule (Focal Melanosis) - p. 348 31. ◆ Oral Melanoacanthoma (Melanoacanthosis) - p. 349 32. ◆ Acquired Melanocytic Nevus (Nevocellular Nevus; Mole) - p. 350 33. ◆ Melanocytic Nevus Variants - p. 353 34. ◆ Leukoplakia (Leukokeratosis; Erythroleukoplakia) - p. 355 35. ◆ Erythroplakia (Erythroplasia; Erythroplasia of Queyrat) - p. 363 36. ◆ Smokeless Tobacco Use and Smokeless Tobacco Keratosis (Snuff Pouch; Snuff Dipper's Lesion; Tobacco Pouch Keratosis; Spit Tobacco Keratosis) - p. 364 37. ◆ Oral Submucous Fibrosis - p. 366 38. ◆ Nicotine Stomatitis (Nicotine Palatinus; Smoker's Palate) - p. 368 39. ◆ Actinic Keratosis (Solar Keratosis) - p. 369 40. ◆ Actinic Cheilosis (Actinic Cheilitis; Solar Cheilosis) - p. 370 41. ◆ Keratoacanthoma (“Self-Healing” Carcinoma; Pseudocarcinoma; Keratocarcinoma; Squamous Cell Carcinoma, Keratoacanthoma Type) - p. 372 42. ◆ Squamous Cell Carcinoma - p. 374 43. ◆ Verrucous Carcinoma (Snuff Dipper's Cancer; Ackerman's Tumor) - p. 389 44. ◆ Spindle Cell Carcinoma (Sarcomatoid Squamous Cell Carcinoma; Polypoid Squamous Cell Carcinoma; Carcinosarcoma; Pseudosarcoma) - p. 391 45. ◆ Adenosquamous Carcinoma - p. 392 46. ◆ Basaloid Squamous Carcinoma (Basaloid Squamous Cell Carcinoma) - p. 392 47. ◆ Carcinoma of the Maxillary Sinus - p. 393 48. ◆ Sinonasal Undifferentiated Carcinoma - p. 394 49. ◆ Nasopharyngeal Carcinoma - p. 395 50. ◆ Basal Cell Carcinoma (Basal Cell Epithelioma; Rodent Ulcer) - p. 397 51. ◆ Merkel Cell Carcinoma (Merkel Cell Tumor; Neuroendocrine Carcinoma of Skin; Small Cell Carcinoma of Skin; Trabecular Carcinoma of Skin) - p. 399 52. ◆ Melanoma (Malignant Melanoma; Melanocarcinoma) - p. 401 53. Bibliography - p. 407 54. 11 Salivary Gland Pathology - p. 422 55. Salivary Gland Tumors - p. 440 56. Bibliography - p. 466 57. 12 Soft Tissue Tumors - p. 473 58. Soft Tissue Sarcomas - p. 515 59. Bibliography - p. 526 60. 13 Hematologic Disorders - p. 533 61. 14 Bone Pathology - p. 572 62. Fibro-Osseous Lesions of the Jaws - p. 592 63. Bibliography - p. 623 64. 15 Odontogenic Cysts and Tumors - p. 632 65. Odontogenic Cysts - p. 632 66. Odontogenic Tumors - p. 652 67. Tumors of Odontogenic Epithelium - p. 653 68. Mixed Odontogenic Tumors - p. 669 69. Tumors of Odontogenic Ectomesenchyme - p. 675 70. Bibliography - p. 681 71. 16 Dermatologic Diseases - p. 690 72. ◆ Ectodermal Dysplasia - p. 690 73. ◆ White Sponge Nevus (Cannon Disease; Familial White Folded Dysplasia) - p. 691 74. ◆ Hereditary Benign Intraepithelial Dyskeratosis (Witkop-Von Sallmann Syndrome) - p. 692 75. ◆ Pachyonychia Congenita (Jadassohn-Lewandowsky Type; Jackson-Lawler Type) - p. 693 76. ◆ Dyskeratosis Congenita (Cole-Engman Syndrome; Zinsser-Cole-Engman Syndrome) - p. 695 77. ◆ Xeroderma Pigmentosum - p. 696 78. ◆ Hereditary Mucoepithelial Dysplasia - p. 697 79. ◆ Incontinentia Pigmenti (Bloch-Sulzberger Syndrome) - p. 698 80. ◆ Darier Disease (Keratosis Follicularis; Dyskeratosis Follicularis; Darier-White Disease) - p. 699 81. ◆ Warty Dyskeratoma (Isolated Darier Disease; Isolated Dyskeratosis Follicularis; Focal Acantholytic Dyskeratosis; Follicular Dyskeratoma) - p. 700 82. ◆ Peutz-Jeghers Syndrome - p. 701 83. ◆ Hereditary Hemorrhagic Telangiectasia (Osler-Weber-Rendu Syndrome) - p. 702 84. ◆ Ehlers-Danlos Syndromes - p. 703 85. ◆ Tuberous Sclerosis (Epiloia; Bourneville-Pringle Syndrome) - p. 705 86. ◆ Multiple Hamartoma Syndrome (Cowden Syndrome; PTEN Hamartoma-Tumor Syndrome) - p. 707 87. ◆ Epidermolysis Bullosa - p. 708 88. ◆ Pemphigus - p. 712 89. ◆ Paraneoplastic Pemphigus (Neoplasia-Induced Pemphigus; Paraneoplastic Autoimmune Multiorgan Syndrome) - p. 716 90. ◆ Mucous Membrane Pemphigoid (Cicatricial Pemphigoid; Benign Mucous Membrane Pemphigoid) - p. 718 91. ◆ Bullous Pemphigoid - p. 722 92. ◆ Erythema Multiforme - p. 723 93. ◆ Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis - p. 725 94. ◆ Erythema Migrans (Geographic Tongue; Benign Migratory Glossitis; Wandering Rash of the Tongue; Erythema Areata Migrans; Stomatitis Areata Migrans) - p. 726 95. ◆ Reactive Arthritis (Reiter Syndrome) - p. 728 96. ◆ Lichen Planus - p. 729 97. ◆ Chronic Ulcerative Stomatitis - p. 734 98. ◆ Graft-Versus-Host Disease - p. 736 99. ◆ Psoriasis - p. 739 100. ◆ Lupus Erythematosus - p. 740 101. ◆ Systemic Sclerosis (Progressive Systemic Sclerosis; Scleroderma; Hide-Bound Disease) - p. 744 102. ◆ CREST Syndrome (Acrosclerosis; Limited Scleroderma) - p. 747 103. ◆ Acanthosis Nigricans - p. 748 104. Bibliography - p. 750 105. 17 Oral Manifestations of Systemic Diseases - p. 761 106. 18 Facial Pain and Neuromuscular Diseases - p. 801 107. 19 Forensic Dentistry - p. 819 108. Appendix Differential Diagnosis of Oral and Maxillofacial Diseases - p. 849 109. Index - p. 872
Be prepared to diagnose and manage any condition you encounter in your practice! This bestselling reference gives you direct access to a complete range of full-color clinical images and patient radiographs that illustrate the differentiating characteristics of lesions in the oral and maxillofacial region. Significantly revised and updated content throughout this edition brings you the latest information on the etiology, clinical features, histopathology, treatment, and prognosis of each disease entity, as well as cutting-edge topics such as bisphosphonate osteonecrosis, the oral complications associated with methamphetamine abuse, solitary fibrous tumors, gene mutation, and plasminogen deficiency.
1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. iv 5. Dedication - p. v 6. Contributors - p. vi 7. Preface - p. vii 8. 1 Developmental Defects of the Oral and Maxillofacial Region - p. 1 9. 2 Abnormalities of Teeth - p. 49 10. Environmental Alterations of Teeth - p. 49 11. Developmental Alterations of Teeth - p. 70 12. Bibliography - p. 105 13. 3 Pulpal and Periapical Disease - p. 111 14. 4 Periodontal Diseases - p. 140 15. 5 Bacterial Infections - p. 164 16. 6 Fungal and Protozoal Diseases - p. 191 17. 7 Viral Infections - p. 218 18. 8 Physical and Chemical Injuries - p. 259 19. 9 Allergies and Immunologic Diseases - p. 303 20. 10 Epithelial Pathology - p. 331 21. ◆ Benign Epithelial Lesions Associated with Human Papillomavirus - p. 331 22. ◆ Molluscum Contagiosum - p. 340 23. ◆ Verruciform Xanthoma - p. 341 24. ◆ Seborrheic Keratosis - p. 342 25. ◆ Sebaceous Hyperplasia - p. 344 26. ◆ Ephelis (Freckle) - p. 345 27. ◆ Actinic Lentigo (Lentigo Solaris; Solar Lentigo; Age Spot; Liver Spot; Senile Lentigo) - p. 345 28. ◆ Lentigo Simplex - p. 346 29. ◆ Melasma (Mask of Pregnancy; Chloasma) - p. 347 30. ◆ Oral Melanotic Macule (Focal Melanosis) - p. 348 31. ◆ Oral Melanoacanthoma (Melanoacanthosis) - p. 349 32. ◆ Acquired Melanocytic Nevus (Nevocellular Nevus; Mole) - p. 350 33. ◆ Melanocytic Nevus Variants - p. 353 34. ◆ Leukoplakia (Leukokeratosis; Erythroleukoplakia) - p. 355 35. ◆ Erythroplakia (Erythroplasia; Erythroplasia of Queyrat) - p. 363 36. ◆ Smokeless Tobacco Use and Smokeless Tobacco Keratosis (Snuff Pouch; Snuff Dipper's Lesion; Tobacco Pouch Keratosis; Spit Tobacco Keratosis) - p. 364 37. ◆ Oral Submucous Fibrosis - p. 366 38. ◆ Nicotine Stomatitis (Nicotine Palatinus; Smoker's Palate) - p. 368 39. ◆ Actinic Keratosis (Solar Keratosis) - p. 369 40. ◆ Actinic Cheilosis (Actinic Cheilitis; Solar Cheilosis) - p. 370 41. ◆ Keratoacanthoma (“Self-Healing” Carcinoma; Pseudocarcinoma; Keratocarcinoma; Squamous Cell Carcinoma, Keratoacanthoma Type) - p. 372 42. ◆ Squamous Cell Carcinoma - p. 374 43. ◆ Verrucous Carcinoma (Snuff Dipper's Cancer; Ackerman's Tumor) - p. 389 44. ◆ Spindle Cell Carcinoma (Sarcomatoid Squamous Cell Carcinoma; Polypoid Squamous Cell Carcinoma; Carcinosarcoma; Pseudosarcoma) - p. 391 45. ◆ Adenosquamous Carcinoma - p. 392 46. ◆ Basaloid Squamous Carcinoma (Basaloid Squamous Cell Carcinoma) - p. 392 47. ◆ Carcinoma of the Maxillary Sinus - p. 393 48. ◆ Sinonasal Undifferentiated Carcinoma - p. 394 49. ◆ Nasopharyngeal Carcinoma - p. 395 50. ◆ Basal Cell Carcinoma (Basal Cell Epithelioma; Rodent Ulcer) - p. 397 51. ◆ Merkel Cell Carcinoma (Merkel Cell Tumor; Neuroendocrine Carcinoma of Skin; Small Cell Carcinoma of Skin; Trabecular Carcinoma of Skin) - p. 399 52. ◆ Melanoma (Malignant Melanoma; Melanocarcinoma) - p. 401 53. Bibliography - p. 407 54. 11 Salivary Gland Pathology - p. 422 55. Salivary Gland Tumors - p. 440 56. Bibliography - p. 466 57. 12 Soft Tissue Tumors - p. 473 58. Soft Tissue Sarcomas - p. 515 59. Bibliography - p. 526 60. 13 Hematologic Disorders - p. 533 61. 14 Bone Pathology - p. 572 62. Fibro-Osseous Lesions of the Jaws - p. 592 63. Bibliography - p. 623 64. 15 Odontogenic Cysts and Tumors - p. 632 65. Odontogenic Cysts - p. 632 66. Odontogenic Tumors - p. 652 67. Tumors of Odontogenic Epithelium - p. 653 68. Mixed Odontogenic Tumors - p. 669 69. Tumors of Odontogenic Ectomesenchyme - p. 675 70. Bibliography - p. 681 71. 16 Dermatologic Diseases - p. 690 72. ◆ Ectodermal Dysplasia - p. 690 73. ◆ White Sponge Nevus (Cannon Disease; Familial White Folded Dysplasia) - p. 691 74. ◆ Hereditary Benign Intraepithelial Dyskeratosis (Witkop-Von Sallmann Syndrome) - p. 692 75. ◆ Pachyonychia Congenita (Jadassohn-Lewandowsky Type; Jackson-Lawler Type) - p. 693 76. ◆ Dyskeratosis Congenita (Cole-Engman Syndrome; Zinsser-Cole-Engman Syndrome) - p. 695 77. ◆ Xeroderma Pigmentosum - p. 696 78. ◆ Hereditary Mucoepithelial Dysplasia - p. 697 79. ◆ Incontinentia Pigmenti (Bloch-Sulzberger Syndrome) - p. 698 80. ◆ Darier Disease (Keratosis Follicularis; Dyskeratosis Follicularis; Darier-White Disease) - p. 699 81. ◆ Warty Dyskeratoma (Isolated Darier Disease; Isolated Dyskeratosis Follicularis; Focal Acantholytic Dyskeratosis; Follicular Dyskeratoma) - p. 700 82. ◆ Peutz-Jeghers Syndrome - p. 701 83. ◆ Hereditary Hemorrhagic Telangiectasia (Osler-Weber-Rendu Syndrome) - p. 702 84. ◆ Ehlers-Danlos Syndromes - p. 703 85. ◆ Tuberous Sclerosis (Epiloia; Bourneville-Pringle Syndrome) - p. 705 86. ◆ Multiple Hamartoma Syndrome (Cowden Syndrome; PTEN Hamartoma-Tumor Syndrome) - p. 707 87. ◆ Epidermolysis Bullosa - p. 708 88. ◆ Pemphigus - p. 712 89. ◆ Paraneoplastic Pemphigus (Neoplasia-Induced Pemphigus; Paraneoplastic Autoimmune Multiorgan Syndrome) - p. 716 90. ◆ Mucous Membrane Pemphigoid (Cicatricial Pemphigoid; Benign Mucous Membrane Pemphigoid) - p. 718 91. ◆ Bullous Pemphigoid - p. 722 92. ◆ Erythema Multiforme - p. 723 93. ◆ Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis - p. 725 94. ◆ Erythema Migrans (Geographic Tongue; Benign Migratory Glossitis; Wandering Rash of the Tongue; Erythema Areata Migrans; Stomatitis Areata Migrans) - p. 726 95. ◆ Reactive Arthritis (Reiter Syndrome) - p. 728 96. ◆ Lichen Planus - p. 729 97. ◆ Chronic Ulcerative Stomatitis - p. 734 98. ◆ Graft-Versus-Host Disease - p. 736 99. ◆ Psoriasis - p. 739 100. ◆ Lupus Erythematosus - p. 740 101. ◆ Systemic Sclerosis (Progressive Systemic Sclerosis; Scleroderma; Hide-Bound Disease) - p. 744 102. ◆ CREST Syndrome (Acrosclerosis; Limited Scleroderma) - p. 747 103. ◆ Acanthosis Nigricans - p. 748 104. Bibliography - p. 750 105. 17 Oral Manifestations of Systemic Diseases - p. 761 106. 18 Facial Pain and Neuromuscular Diseases - p. 801 107. 19 Forensic Dentistry - p. 819 108. Appendix Differential Diagnosis of Oral and Maxillofacial Diseases - p. 849 109. Index - p. 872
