Written by two leaders in the field of pediatric dermatology, this classic text provides both detailed content for the specialist and easily accessible information for the non-dermatologist and less experienced clinician. Paller and Mancini – Hurwitz Clinical Pediatric Dermatology, 6th Edition, comprehensively covers the full range of skin disorders in children, offering authoritative, practical guidance on diagnosis and treatment in a single volume. This award-winning, evidence-based text has been fully revised and updated, and is an essential resource for anyone who sees children with skin disorders.
1. Cover image - p. cover 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Dedication - p. v 6. Preface - p. vi 7. List of Tables - p. vii 8. List of Illustrations - p. viii 9. Multimedia Resources - p. vi 10. 1. An overview of dermatologic diagnosis and procedures - p. viii 11. 2. Cutaneous disorders of the newborn - p. 10 12. Neonatal skin - p. 10 13. Physiologic phenomena of the newborn - p. 11 14. Cephalohematoma - p. 13 15. Caput succedaneum - p. 13 16. Complications from fetal and neonatal diagnostic procedures - p. 13 17. Abnormalities of subcutaneous tissue - p. 14 18. Miscellaneous cutaneous disorders - p. 16 19. Developmental abnormalities of the newborn - p. 26 20. Congenital infections of the newborn - p. 33 21. Key references - p. 41 22. References - p. 41 23. 3. Eczematous eruptions in childhood - p. 41 24. Atopic dermatitis - p. 41 25. Pityriasis alba - p. 61 26. Hyperimmunoglobulinemia E syndrome - p. 61 27. Wiskott–Aldrich syndrome - p. 63 28. Lichen simplex chronicus - p. 63 29. Seborrheic dermatitis - p. 64 30. Intertrigo - p. 66 31. Dyshidrotic eczema - p. 66 32. Juvenile plantar dermatosis - p. 67 33. Frictional lichenoid dermatitis - p. 67 34. Nummular dermatitis - p. 67 35. Winter eczema - p. 68 36. Lichen striatus - p. 68 37. Contact dermatitis - p. 68 38. Key references - p. 81 39. References - p. 81 40. 4. Papulosquamous and related disorders - p. 81 41. Childhood psoriasis - p. 81 42. Reactive arthritis - p. 95 43. Pityriasis rubra pilaris - p. 97 44. Pityriasis lichenoides - p. 99 45. Pityriasis rosea - p. 100 46. Lichen planus - p. 102 47. Lichen nitidus - p. 105 48. Keratosis lichenoides chronica - p. 106 49. Key references - p. 107 50. References - p. 107 51. 5. Hereditary disorders of cornification (the ichthyoses and palmoplantar keratodermas) - p. 107 52. Nonsyndromic forms of ichthyosis - p. 107 53. Syndromic forms of ichthyosis - p. 120 54. Treatment of nonsyndromic and syndromic ichthyoses - p. 127 55. Other disorders of differentiation - p. 129 56. Porokeratoses - p. 130 57. Palmoplantar keratodermas - p. 133 58. Key references - p. 138 59. References - p. 138 60. 6. Hereditary disorders of the dermis - p. 138 61. Ehlers–Danlos syndrome - p. 138 62. Marfan syndrome - p. 143 63. Osteogenesis imperfecta - p. 145 64. Cutis laxa - p. 147 65. Pseudoxanthoma elasticum - p. 151 66. Elastosis perforans serpiginosa - p. 152 67. Focal dermal hypoplasia - p. 153 68. Laminopathies - p. 154 69. Restrictive dermopathy - p. 155 70. Werner syndrome - p. 156 71. Stiff skin syndrome - p. 156 72. Winchester syndrome - p. 156 73. Buschke–Ollendorff syndrome - p. 157 74. Lipoid proteinosis - p. 157 75. Infantile systemic hyalinosis and juvenile hyaline fibromatosis - p. 159 76. Key references - p. 159 77. References - p. 159 78. 7. Disorders of hair and nails - p. 159 79. Hair - p. 159 80. Neonatal hair - p. 159 81. Tools for diagnosis of hair loss disorders - p. 159 82. Alopecias - p. 160 83. Eruptive vellus hair cysts - p. 187 84. Hypertrichosis and hirsutism - p. 188 85. Pigmentary changes of hair - p. 192 86. Nails - p. 193 87. Key references - p. 204 88. References - p. 204 89. 8. Acne vulgaris and other disorders of the sebaceous and sweat glands - p. 204 90. Disorders of the sebaceous glands - p. 204 91. Disorders of the apocrine glands - p. 221 92. Disorders of the eccrine glands - p. 223 93. Key references - p. 226 94. References - p. 226 95. 9. Cutaneous tumors and tumor syndromes - p. 226 96. Pigmented lesions - p. 226 97. Melanocytic nevi - p. 226 98. Tumors of the epidermis - p. 239 99. Tumors of the oral mucosa - p. 245 100. Tumors of the epidermal appendages - p. 246 101. Dermal tumors - p. 250 102. Fibromatoses - p. 256 103. Tumors of fat, muscles, and bone - p. 258 104. Miscellaneous - p. 263 105. Key references - p. 267 106. References - p. 267 107. 10. Histiocytoses and malignant skin diseases - p. 267 108. Langerhans cell histiocytosis - p. 267 109. Juvenile Xanthogranuloma - p. 273 110. Xanthoma Disseminatum - p. 274 111. Benign Cephalic Histiocytosis - p. 275 112. Necrobiotic Xanthogranuloma - p. 275 113. Generalized Eruptive Histiocytoma - p. 275 114. Progressive nodular histiocytoma - p. 275 115. Multicentric reticulohistiocytosis - p. 276 116. Hemophagocytic lymphohistiocytosis - p. 276 117. Sinus histiocytosis with massive lymphadenopathy (Rosai–Dorfman disease) - p. 276 118. Cutaneous pseudolymphoma - p. 276 119. Leukemia cutis - p. 277 120. Lymphomatoid papulosis - p. 279 121. Lymphoma cutis - p. 280 122. Cutaneous T-cell lymphoma - p. 281 123. Neuroblastoma - p. 284 124. Rhabdomyosarcoma - p. 284 125. Key references - p. 286 126. References - p. 286 127. 11. Disorders of pigmentation - p. 286 128. Disorders of abnormal pigmentation - p. 287 129. Disorders of hyperpigmentation - p. 309 130. Key references - p. 325 131. References - p. 325 132. 12. Infantile hemangiomas, vascular malformations, and other vascular disorders of infancy and childhood - p. 325 133. Classification of vascular lesions - p. 325 134. Vascular tumors and tumor syndromes - p. 325 135. Vascular malformations and malformation syndromes - p. 345 136. Disorders of lymphatic vessels - p. 354 137. Disorders associated with vascular dilation or constriction - p. 358 138. Pigmented purpuric eruptions - p. 364 139. Purpura fulminans - p. 366 140. Gardner–Diamond syndrome - p. 366 141. Scurvy - p. 368 142. Key references - p. 368 143. References - p. 368 144. 13. Bullous disorders of childhood - p. 368 145. Hereditary blistering disorders - p. 368 146. Key references - p. 390 147. References - p. 390 148. 14. Bacterial, mycobacterial, and protozoal infections of the skin - p. 390 149. Bacterial infections - p. 391 150. Nontuberculous (“atypical”) mycobacterial infections - p. 405 151. Tuberculosis of the skin - p. 407 152. The tuberculid disorders - p. 408 153. Leprosy - p. 409 154. Anthrax - p. 410 155. Cat-scratch disease - p. 411 156. Disorders resulting from fungus-like bacteria - p. 411 157. Treponemal infections - p. 413 158. Protozoal disorders - p. 417 159. Key references - p. 419 160. References - p. 419 161. 15. Viral diseases of the skin - p. 419 162. Herpes simplex virus infection - p. 419 163. Herpes zoster - p. 424 164. Viral-like disorders of the oral mucosa - p. 426 165. Warts - p. 428 166. Molluscum contagiosum - p. 435 167. Cowpox and pseudocowpox - p. 438 168. Orf - p. 439 169. Smallpox - p. 439 170. Acquired immunodeficiency syndrome in children - p. 440 171. Key references - p. 443 172. References - p. 443 173. 16. Exanthematous diseases of childhood - p. 443 174. Varicella (chickenpox) - p. 443 175. Rubeola (measles) - p. 446 176. Scarlet fever - p. 449 177. Rubella (German measles) - p. 450 178. Filatow–Dukes disease - p. 451 179. Erythema infectiosum - p. 451 180. Roseola infantum - p. 453 181. Other viral exanthems - p. 455 182. Exanthems associated with mycoplasma pneumoniae infection - p. 462 183. Rickettsial diseases - p. 462 184. Key references - p. 466 185. References - p. 466 186. 17. Skin disorders caused by fungi - p. 466 187. Superficial fungal infections - p. 466 188. Candidiasis - p. 482 189. Deep fungal disorders - p. 487 190. Key references - p. 496 191. References - p. 496 192. 18. Infestations, bites, and stings - p. 496 193. Arthropods - p. 496 194. Other cutaneous parasites - p. 515 195. Seabather’s eruption - p. 516 196. Jellyfish stings - p. 517 197. Key references - p. 519 198. References - p. 519 199. 19. Photosensitivity and photoreactions - p. 519 200. Tanning and sunburn reactions - p. 519 201. Photodermatoses - p. 522 202. Photosensitivity induced by exogenous sources - p. 526 203. Genetic disorders associated with photosensitivity - p. 528 204. Pellagra - p. 534 205. The porphyrias - p. 534 206. Key references - p. 540 207. References - p. 540 208. 20. Urticarias and other hypersensitivity disorders - p. 540 209. Allergic reactions - p. 541 210. Urticaria - p. 541 211. Contact urticaria - p. 545 212. Physical urticarias - p. 545 213. Anaphylaxis - p. 547 214. Angioedema - p. 548 215. C1 inhibitor–hereditary angioneurotic edema - p. 549 216. Scombroid and ciguatera fish poisoning - p. 549 217. Serum sickness and serum sickness–like reactions - p. 550 218. Exanthematous eruptions - p. 551 219. Drug reaction with eosinophilia and systemic symptoms - p. 551 220. Stevens–Johnson syndrome and toxic epidermal necrolysis - p. 553 221. Reactive infectious mucocutaneous or mucosal-predominant eruption - p. 556 222. Fixed drug eruption - p. 556 223. Acute generalized exanthematous pustulosis - p. 557 224. Erythema multiforme - p. 558 225. Annular erythemas - p. 559 226. Panniculitis - p. 560 227. Erythema nodosum - p. 563 228. Eccrine hidradenitis - p. 563 229. Cutaneous reactions to cold - p. 564 230. Cutaneous reactions to heat - p. 566 231. Sweet syndrome (acute febrile neutrophilic dermatosis) - p. 567 232. Bowel-associated dermatosis-arthritis syndrome - p. 568 233. Hypereosinophilic syndrome - p. 569 234. Wells syndrome - p. 569 235. Pregnancy and pregnancy-related dermatoses - p. 569 236. Autoimmune progesterone dermatitis - p. 571 237. Key references - p. 571 238. References - p. 571 239. 21. Vasculitic disorders - p. 571 240. 22. Collagen vascular disorders - p. 587 241. Juvenile idiopathic arthritis - p. 587 242. Systemic lupus erythematosus - p. 590 243. Cutaneous lupus erythematosus - p. 590 244. Nonspecific clinical manifestations of SLE - p. 594 245. Laboratory features in the diagnosis of SLE - p. 596 246. Drug-induced lupus erythematosus - p. 596 247. Prognosis and therapy for SLE - p. 597 248. Neonatal lupus erythematosus - p. 598 249. Antiphospholipid antibody syndrome - p. 601 250. Degos disease - p. 601 251. Juvenile dermatomyositis - p. 601 252. Systemic sclerosis (scleroderma) - p. 607 253. Eosinophilic fasciitis - p. 611 254. Nephrogenic systemic fibrosis - p. 611 255. Scleredema - p. 612 256. Morphea - p. 612 257. Lichen sclerosus et atrophicus - p. 616 258. Anetoderma - p. 618 259. Relapsing polychondritis - p. 619 260. Sjögren syndrome - p. 619 261. Mixed connective tissue disease - p. 620 262. Key references - p. 622 263. References - p. 622 264. 23. Endocrine disorders and the skin - p. 622 265. Thyroid disorders - p. 622 266. Parathyroid disorders - p. 623 267. Disorders of the adrenal glands - p. 626 268. Disorders of androgen excess - p. 630 269. Gonadal dysgenesis/Turner syndrome - p. 632 270. Pituitary disorders - p. 633 271. Multiple Endocrine Neoplasia Syndromes - p. 633 272. Autoimmune Polyglandular syndromes - p. 635 273. Mccune–Albright syndrome - p. 636 274. Disorders associated with diabetes mellitus - p. 637 275. Scleredema diabeticorum - p. 642 276. Glucagonoma syndrome - p. 642 277. Key references - p. 643 278. References - p. 643 279. 24. Inborn errors of metabolism - p. 643 280. Phenylketonuria - p. 643 281. Disorders of tyrosine metabolism - p. 643 282. Cobalamin deficiency - p. 644 283. Homocystinuria - p. 644 284. Trimethylaminuria - p. 645 285. Wilson disease (Hepatolenticular degeneration) - p. 645 286. Lesch–Nyhan syndrome - p. 645 287. Dermatitis from nutritional abnormalities - p. 646 288. Disorders that resemble acrodermatitis enteropathica - p. 647 289. The hyperlipidemias - p. 650 290. The mucopolysaccharidoses - p. 656 291. Other storage disorders - p. 658 292. Key references - p. 661 293. References - p. 661 294. 25. Skin signs of other systemic diseases - p. 661 295. Primary immunodeficiency disorders - p. 661 296. Graft-Versus-Host Disease - p. 666 297. Anorexia nervosa and bulimia - p. 671 298. Autoinflammatory disorders - p. 671 299. Polygenic forms of autoinflammatory disorders - p. 673 300. Amicrobial pustulosis of the folds - p. 675 301. Behçet disease - p. 675 302. Sarcoidosis - p. 679 303. Other inflammasomopathies - p. 683 304. Inflammasomopathies with pyoderma gangrenosum - p. 684 305. CANDLE syndrome - p. 685 306. The ubiquitinopathies (relopathies) - p. 685 307. LUBAC component deficiency - p. 685 308. Key references - p. 689 309. References - p. 689 310. 26. Abuse and factitial disorders - p. 689 311. Index - p. 705
Written by two leaders in the field of pediatric dermatology, this classic text provides both detailed content for the specialist and easily accessible information for the non-dermatologist and less experienced clinician. Paller and Mancini – Hurwitz Clinical Pediatric Dermatology, 6th Edition, comprehensively covers the full range of skin disorders in children, offering authoritative, practical guidance on diagnosis and treatment in a single volume. This award-winning, evidence-based text has been fully revised and updated, and is an essential resource for anyone who sees children with skin disorders.
1. Cover image - p. cover 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Dedication - p. v 6. Preface - p. vi 7. List of Tables - p. vii 8. List of Illustrations - p. viii 9. Multimedia Resources - p. vi 10. 1. An overview of dermatologic diagnosis and procedures - p. viii 11. 2. Cutaneous disorders of the newborn - p. 10 12. Neonatal skin - p. 10 13. Physiologic phenomena of the newborn - p. 11 14. Cephalohematoma - p. 13 15. Caput succedaneum - p. 13 16. Complications from fetal and neonatal diagnostic procedures - p. 13 17. Abnormalities of subcutaneous tissue - p. 14 18. Miscellaneous cutaneous disorders - p. 16 19. Developmental abnormalities of the newborn - p. 26 20. Congenital infections of the newborn - p. 33 21. Key references - p. 41 22. References - p. 41 23. 3. Eczematous eruptions in childhood - p. 41 24. Atopic dermatitis - p. 41 25. Pityriasis alba - p. 61 26. Hyperimmunoglobulinemia E syndrome - p. 61 27. Wiskott–Aldrich syndrome - p. 63 28. Lichen simplex chronicus - p. 63 29. Seborrheic dermatitis - p. 64 30. Intertrigo - p. 66 31. Dyshidrotic eczema - p. 66 32. Juvenile plantar dermatosis - p. 67 33. Frictional lichenoid dermatitis - p. 67 34. Nummular dermatitis - p. 67 35. Winter eczema - p. 68 36. Lichen striatus - p. 68 37. Contact dermatitis - p. 68 38. Key references - p. 81 39. References - p. 81 40. 4. Papulosquamous and related disorders - p. 81 41. Childhood psoriasis - p. 81 42. Reactive arthritis - p. 95 43. Pityriasis rubra pilaris - p. 97 44. Pityriasis lichenoides - p. 99 45. Pityriasis rosea - p. 100 46. Lichen planus - p. 102 47. Lichen nitidus - p. 105 48. Keratosis lichenoides chronica - p. 106 49. Key references - p. 107 50. References - p. 107 51. 5. Hereditary disorders of cornification (the ichthyoses and palmoplantar keratodermas) - p. 107 52. Nonsyndromic forms of ichthyosis - p. 107 53. Syndromic forms of ichthyosis - p. 120 54. Treatment of nonsyndromic and syndromic ichthyoses - p. 127 55. Other disorders of differentiation - p. 129 56. Porokeratoses - p. 130 57. Palmoplantar keratodermas - p. 133 58. Key references - p. 138 59. References - p. 138 60. 6. Hereditary disorders of the dermis - p. 138 61. Ehlers–Danlos syndrome - p. 138 62. Marfan syndrome - p. 143 63. Osteogenesis imperfecta - p. 145 64. Cutis laxa - p. 147 65. Pseudoxanthoma elasticum - p. 151 66. Elastosis perforans serpiginosa - p. 152 67. Focal dermal hypoplasia - p. 153 68. Laminopathies - p. 154 69. Restrictive dermopathy - p. 155 70. Werner syndrome - p. 156 71. Stiff skin syndrome - p. 156 72. Winchester syndrome - p. 156 73. Buschke–Ollendorff syndrome - p. 157 74. Lipoid proteinosis - p. 157 75. Infantile systemic hyalinosis and juvenile hyaline fibromatosis - p. 159 76. Key references - p. 159 77. References - p. 159 78. 7. Disorders of hair and nails - p. 159 79. Hair - p. 159 80. Neonatal hair - p. 159 81. Tools for diagnosis of hair loss disorders - p. 159 82. Alopecias - p. 160 83. Eruptive vellus hair cysts - p. 187 84. Hypertrichosis and hirsutism - p. 188 85. Pigmentary changes of hair - p. 192 86. Nails - p. 193 87. Key references - p. 204 88. References - p. 204 89. 8. Acne vulgaris and other disorders of the sebaceous and sweat glands - p. 204 90. Disorders of the sebaceous glands - p. 204 91. Disorders of the apocrine glands - p. 221 92. Disorders of the eccrine glands - p. 223 93. Key references - p. 226 94. References - p. 226 95. 9. Cutaneous tumors and tumor syndromes - p. 226 96. Pigmented lesions - p. 226 97. Melanocytic nevi - p. 226 98. Tumors of the epidermis - p. 239 99. Tumors of the oral mucosa - p. 245 100. Tumors of the epidermal appendages - p. 246 101. Dermal tumors - p. 250 102. Fibromatoses - p. 256 103. Tumors of fat, muscles, and bone - p. 258 104. Miscellaneous - p. 263 105. Key references - p. 267 106. References - p. 267 107. 10. Histiocytoses and malignant skin diseases - p. 267 108. Langerhans cell histiocytosis - p. 267 109. Juvenile Xanthogranuloma - p. 273 110. Xanthoma Disseminatum - p. 274 111. Benign Cephalic Histiocytosis - p. 275 112. Necrobiotic Xanthogranuloma - p. 275 113. Generalized Eruptive Histiocytoma - p. 275 114. Progressive nodular histiocytoma - p. 275 115. Multicentric reticulohistiocytosis - p. 276 116. Hemophagocytic lymphohistiocytosis - p. 276 117. Sinus histiocytosis with massive lymphadenopathy (Rosai–Dorfman disease) - p. 276 118. Cutaneous pseudolymphoma - p. 276 119. Leukemia cutis - p. 277 120. Lymphomatoid papulosis - p. 279 121. Lymphoma cutis - p. 280 122. Cutaneous T-cell lymphoma - p. 281 123. Neuroblastoma - p. 284 124. Rhabdomyosarcoma - p. 284 125. Key references - p. 286 126. References - p. 286 127. 11. Disorders of pigmentation - p. 286 128. Disorders of abnormal pigmentation - p. 287 129. Disorders of hyperpigmentation - p. 309 130. Key references - p. 325 131. References - p. 325 132. 12. Infantile hemangiomas, vascular malformations, and other vascular disorders of infancy and childhood - p. 325 133. Classification of vascular lesions - p. 325 134. Vascular tumors and tumor syndromes - p. 325 135. Vascular malformations and malformation syndromes - p. 345 136. Disorders of lymphatic vessels - p. 354 137. Disorders associated with vascular dilation or constriction - p. 358 138. Pigmented purpuric eruptions - p. 364 139. Purpura fulminans - p. 366 140. Gardner–Diamond syndrome - p. 366 141. Scurvy - p. 368 142. Key references - p. 368 143. References - p. 368 144. 13. Bullous disorders of childhood - p. 368 145. Hereditary blistering disorders - p. 368 146. Key references - p. 390 147. References - p. 390 148. 14. Bacterial, mycobacterial, and protozoal infections of the skin - p. 390 149. Bacterial infections - p. 391 150. Nontuberculous (“atypical”) mycobacterial infections - p. 405 151. Tuberculosis of the skin - p. 407 152. The tuberculid disorders - p. 408 153. Leprosy - p. 409 154. Anthrax - p. 410 155. Cat-scratch disease - p. 411 156. Disorders resulting from fungus-like bacteria - p. 411 157. Treponemal infections - p. 413 158. Protozoal disorders - p. 417 159. Key references - p. 419 160. References - p. 419 161. 15. Viral diseases of the skin - p. 419 162. Herpes simplex virus infection - p. 419 163. Herpes zoster - p. 424 164. Viral-like disorders of the oral mucosa - p. 426 165. Warts - p. 428 166. Molluscum contagiosum - p. 435 167. Cowpox and pseudocowpox - p. 438 168. Orf - p. 439 169. Smallpox - p. 439 170. Acquired immunodeficiency syndrome in children - p. 440 171. Key references - p. 443 172. References - p. 443 173. 16. Exanthematous diseases of childhood - p. 443 174. Varicella (chickenpox) - p. 443 175. Rubeola (measles) - p. 446 176. Scarlet fever - p. 449 177. Rubella (German measles) - p. 450 178. Filatow–Dukes disease - p. 451 179. Erythema infectiosum - p. 451 180. Roseola infantum - p. 453 181. Other viral exanthems - p. 455 182. Exanthems associated with mycoplasma pneumoniae infection - p. 462 183. Rickettsial diseases - p. 462 184. Key references - p. 466 185. References - p. 466 186. 17. Skin disorders caused by fungi - p. 466 187. Superficial fungal infections - p. 466 188. Candidiasis - p. 482 189. Deep fungal disorders - p. 487 190. Key references - p. 496 191. References - p. 496 192. 18. Infestations, bites, and stings - p. 496 193. Arthropods - p. 496 194. Other cutaneous parasites - p. 515 195. Seabather’s eruption - p. 516 196. Jellyfish stings - p. 517 197. Key references - p. 519 198. References - p. 519 199. 19. Photosensitivity and photoreactions - p. 519 200. Tanning and sunburn reactions - p. 519 201. Photodermatoses - p. 522 202. Photosensitivity induced by exogenous sources - p. 526 203. Genetic disorders associated with photosensitivity - p. 528 204. Pellagra - p. 534 205. The porphyrias - p. 534 206. Key references - p. 540 207. References - p. 540 208. 20. Urticarias and other hypersensitivity disorders - p. 540 209. Allergic reactions - p. 541 210. Urticaria - p. 541 211. Contact urticaria - p. 545 212. Physical urticarias - p. 545 213. Anaphylaxis - p. 547 214. Angioedema - p. 548 215. C1 inhibitor–hereditary angioneurotic edema - p. 549 216. Scombroid and ciguatera fish poisoning - p. 549 217. Serum sickness and serum sickness–like reactions - p. 550 218. Exanthematous eruptions - p. 551 219. Drug reaction with eosinophilia and systemic symptoms - p. 551 220. Stevens–Johnson syndrome and toxic epidermal necrolysis - p. 553 221. Reactive infectious mucocutaneous or mucosal-predominant eruption - p. 556 222. Fixed drug eruption - p. 556 223. Acute generalized exanthematous pustulosis - p. 557 224. Erythema multiforme - p. 558 225. Annular erythemas - p. 559 226. Panniculitis - p. 560 227. Erythema nodosum - p. 563 228. Eccrine hidradenitis - p. 563 229. Cutaneous reactions to cold - p. 564 230. Cutaneous reactions to heat - p. 566 231. Sweet syndrome (acute febrile neutrophilic dermatosis) - p. 567 232. Bowel-associated dermatosis-arthritis syndrome - p. 568 233. Hypereosinophilic syndrome - p. 569 234. Wells syndrome - p. 569 235. Pregnancy and pregnancy-related dermatoses - p. 569 236. Autoimmune progesterone dermatitis - p. 571 237. Key references - p. 571 238. References - p. 571 239. 21. Vasculitic disorders - p. 571 240. 22. Collagen vascular disorders - p. 587 241. Juvenile idiopathic arthritis - p. 587 242. Systemic lupus erythematosus - p. 590 243. Cutaneous lupus erythematosus - p. 590 244. Nonspecific clinical manifestations of SLE - p. 594 245. Laboratory features in the diagnosis of SLE - p. 596 246. Drug-induced lupus erythematosus - p. 596 247. Prognosis and therapy for SLE - p. 597 248. Neonatal lupus erythematosus - p. 598 249. Antiphospholipid antibody syndrome - p. 601 250. Degos disease - p. 601 251. Juvenile dermatomyositis - p. 601 252. Systemic sclerosis (scleroderma) - p. 607 253. Eosinophilic fasciitis - p. 611 254. Nephrogenic systemic fibrosis - p. 611 255. Scleredema - p. 612 256. Morphea - p. 612 257. Lichen sclerosus et atrophicus - p. 616 258. Anetoderma - p. 618 259. Relapsing polychondritis - p. 619 260. Sjögren syndrome - p. 619 261. Mixed connective tissue disease - p. 620 262. Key references - p. 622 263. References - p. 622 264. 23. Endocrine disorders and the skin - p. 622 265. Thyroid disorders - p. 622 266. Parathyroid disorders - p. 623 267. Disorders of the adrenal glands - p. 626 268. Disorders of androgen excess - p. 630 269. Gonadal dysgenesis/Turner syndrome - p. 632 270. Pituitary disorders - p. 633 271. Multiple Endocrine Neoplasia Syndromes - p. 633 272. Autoimmune Polyglandular syndromes - p. 635 273. Mccune–Albright syndrome - p. 636 274. Disorders associated with diabetes mellitus - p. 637 275. Scleredema diabeticorum - p. 642 276. Glucagonoma syndrome - p. 642 277. Key references - p. 643 278. References - p. 643 279. 24. Inborn errors of metabolism - p. 643 280. Phenylketonuria - p. 643 281. Disorders of tyrosine metabolism - p. 643 282. Cobalamin deficiency - p. 644 283. Homocystinuria - p. 644 284. Trimethylaminuria - p. 645 285. Wilson disease (Hepatolenticular degeneration) - p. 645 286. Lesch–Nyhan syndrome - p. 645 287. Dermatitis from nutritional abnormalities - p. 646 288. Disorders that resemble acrodermatitis enteropathica - p. 647 289. The hyperlipidemias - p. 650 290. The mucopolysaccharidoses - p. 656 291. Other storage disorders - p. 658 292. Key references - p. 661 293. References - p. 661 294. 25. Skin signs of other systemic diseases - p. 661 295. Primary immunodeficiency disorders - p. 661 296. Graft-Versus-Host Disease - p. 666 297. Anorexia nervosa and bulimia - p. 671 298. Autoinflammatory disorders - p. 671 299. Polygenic forms of autoinflammatory disorders - p. 673 300. Amicrobial pustulosis of the folds - p. 675 301. Behçet disease - p. 675 302. Sarcoidosis - p. 679 303. Other inflammasomopathies - p. 683 304. Inflammasomopathies with pyoderma gangrenosum - p. 684 305. CANDLE syndrome - p. 685 306. The ubiquitinopathies (relopathies) - p. 685 307. LUBAC component deficiency - p. 685 308. Key references - p. 689 309. References - p. 689 310. 26. Abuse and factitial disorders - p. 689 311. Index - p. 705
