Chronic Heart Failure: Pathophysiology, Risk factors, and Mechanisms is the first of two separate but closely related volumes which aim to provide an inclusive overview on Chronic Heart Failure (CHF).
This first volume is focused on the epidemiology, classification, molecular mechanisms, pathophysiology, causes, identification and interactions of heart failure. It will explain the uncertainties and issues in Heart Failure by helping readers understand the physiopathology of CHF in the light of behavioural risk factors. 2D and 3D speckle tracking echocardiography have been used to quantify regional alterations of longitudinal strain and area strain, through their polar projection, which allows a further evaluation of both the site and extent of myocardial damage. The analysis of strain can identify subclinical cardiac failure (myocyte remodelling) which is a major issue in CHF. Myocardial Strain, measure by speckle tracking echocardiography, is frequently attenuated in these conditions and can be utilized for the evaluation of disease progression and the effect of therapeutic interventions as well as prevention because it could be a manifestation of behavioural risk factors.
These 2 separate volumes serves as essential references to both researchers and practicing clinicians, proposing novel methods of research by using behavioural and environmental risk factors as intervention agent, as well as discussing deficiency in the present approaches in management of HF and proposing new methods of early diagnosis and therapies for the clinical management of CHF.
1. Pathophysiology, Risk Factors, and Management of Chronic Heart Failure - p. ii 2. Cover - p. ii 3. Title Page - p. ii 4. Copyright Page - p. iv 5. Table of Contents - p. iv 6. List of Contributors - p. xv 7. About the Editors - p. xix 8. Foreword by Naranjan S. Dhalla - p. xxi 9. Foreword by Navin C. Nanda - p. xxiii 10. Preface - p. xxv 11. Editorial: The six stages of chronic heart failure - p. xxvii 12. Chapter 1 History of medicine from ancient times to present - p. 3 13. Chapter 2 Epidemiology and mortality due to heart failure - p. 23 14. Chapter 3 Behavioral risk factors of chronic heart failure - p. 41 15. Chapter 4 Nutritional factors in the pathogenesis of heart failure: a review - p. 53 16. Chapter 5 Evolution of the natural history of myocardial twist and diastolic dysfunction as cardiac dysfunction - p. 65 17. Chapter 6 Preheart failure: a stage of chronic heart failure - p. 81 18. Chapter 7 Classification of chronic heart failure as per New York Heart Association - p. 95 19. Chapter 8 Molecular and cellular biology and genetic factors in chronic heart failure - p. 103 20. Chapter 9 Pathophysiology of chronic heart failure - p. 115 21. Chapter 10 Circadian dysfunction in the pathogenesis of heart failure - p. 121 22. Chapter 11 Cardiac remodeling in chronic heart failure: pathophysiological implications - p. 135 23. Chapter 12 Pathophysiology of abnormalities involving calcium signalling during cardiac muscle contraction - p. 149 24. Chapter 13 Abnormalities in the cardiac relaxation - p. 159 25. Chapter 14 Renal dysfunction and heart disease: elucidating the cardiorenal relationship approaches leading to heart failure - p. 171 26. Chapter 15 Role of brain with reference to autonomic nervous system dysfunctions, as predisposing factor of chronic heart failure? - p. 177 27. Chapter 16 Heart failure in chronic kidney disease - p. 187 28. Chapter 17 Role of noninvasive imaging with reference to speckle-tracking echocardiography - p. 197 29. Chapter 18 Advances in echocardiographic imaging in chronic heart failure - p. 211 30. Chapter 19 Congenital heart diseases - p. 235 31. Chapter 20 Cardiac magnetic resonance imaging in chronic heart failure - p. 243 32. Chapter 21 Role of pulmonary ultrasound in heart failure - p. 261 33. Chapter 22 Physical training in heart failure - p. 267 34. Chapter 23 Nutritional management in heart failure - p. 279 35. Chapter 24 Management of arrhythmia in chronic heart failure - p. 295 36. Chapter 25 Ivabradine: sinus rhythm control in heart failure - p. 311 37. Chapter 26 Guidelines for the management of chronic heart failure - p. 325 38. Chapter 27 Renin–angiotensin–aldosterone system inhibitors in the heart failure management - p. 343 39. Chapter 28 Beta-blocker therapy among patients with heart failure - p. 351 40. Chapter 29 Treatment of heart failure using angiotensin receptor neprilysin inhibitor - p. 361 41. Chapter 30 Effects of mineralocorticoid antagonist therapy in heart failure - p. 369 42. Chapter 31 Sodium glucose transporters inhibitors in the management of heart failure - p. 377 43. Chapter 32 Role of vasodilators and digitalis in heart failure - p. 389 44. Chapter 33 Vericiguat as part of a multidrug approach following a worsening heart failure event - p. 397 45. Index - p. 409 46. Index - Continued - p. 417
Chronic Heart Failure: Pathophysiology, Risk factors, and Mechanisms is the first of two separate but closely related volumes which aim to provide an inclusive overview on Chronic Heart Failure (CHF).
This first volume is focused on the epidemiology, classification, molecular mechanisms, pathophysiology, causes, identification and interactions of heart failure. It will explain the uncertainties and issues in Heart Failure by helping readers understand the physiopathology of CHF in the light of behavioural risk factors. 2D and 3D speckle tracking echocardiography have been used to quantify regional alterations of longitudinal strain and area strain, through their polar projection, which allows a further evaluation of both the site and extent of myocardial damage. The analysis of strain can identify subclinical cardiac failure (myocyte remodelling) which is a major issue in CHF. Myocardial Strain, measure by speckle tracking echocardiography, is frequently attenuated in these conditions and can be utilized for the evaluation of disease progression and the effect of therapeutic interventions as well as prevention because it could be a manifestation of behavioural risk factors.
These 2 separate volumes serves as essential references to both researchers and practicing clinicians, proposing novel methods of research by using behavioural and environmental risk factors as intervention agent, as well as discussing deficiency in the present approaches in management of HF and proposing new methods of early diagnosis and therapies for the clinical management of CHF.
1. Pathophysiology, Risk Factors, and Management of Chronic Heart Failure - p. ii 2. Cover - p. ii 3. Title Page - p. ii 4. Copyright Page - p. iv 5. Table of Contents - p. iv 6. List of Contributors - p. xv 7. About the Editors - p. xix 8. Foreword by Naranjan S. Dhalla - p. xxi 9. Foreword by Navin C. Nanda - p. xxiii 10. Preface - p. xxv 11. Editorial: The six stages of chronic heart failure - p. xxvii 12. Chapter 1 History of medicine from ancient times to present - p. 3 13. Chapter 2 Epidemiology and mortality due to heart failure - p. 23 14. Chapter 3 Behavioral risk factors of chronic heart failure - p. 41 15. Chapter 4 Nutritional factors in the pathogenesis of heart failure: a review - p. 53 16. Chapter 5 Evolution of the natural history of myocardial twist and diastolic dysfunction as cardiac dysfunction - p. 65 17. Chapter 6 Preheart failure: a stage of chronic heart failure - p. 81 18. Chapter 7 Classification of chronic heart failure as per New York Heart Association - p. 95 19. Chapter 8 Molecular and cellular biology and genetic factors in chronic heart failure - p. 103 20. Chapter 9 Pathophysiology of chronic heart failure - p. 115 21. Chapter 10 Circadian dysfunction in the pathogenesis of heart failure - p. 121 22. Chapter 11 Cardiac remodeling in chronic heart failure: pathophysiological implications - p. 135 23. Chapter 12 Pathophysiology of abnormalities involving calcium signalling during cardiac muscle contraction - p. 149 24. Chapter 13 Abnormalities in the cardiac relaxation - p. 159 25. Chapter 14 Renal dysfunction and heart disease: elucidating the cardiorenal relationship approaches leading to heart failure - p. 171 26. Chapter 15 Role of brain with reference to autonomic nervous system dysfunctions, as predisposing factor of chronic heart failure? - p. 177 27. Chapter 16 Heart failure in chronic kidney disease - p. 187 28. Chapter 17 Role of noninvasive imaging with reference to speckle-tracking echocardiography - p. 197 29. Chapter 18 Advances in echocardiographic imaging in chronic heart failure - p. 211 30. Chapter 19 Congenital heart diseases - p. 235 31. Chapter 20 Cardiac magnetic resonance imaging in chronic heart failure - p. 243 32. Chapter 21 Role of pulmonary ultrasound in heart failure - p. 261 33. Chapter 22 Physical training in heart failure - p. 267 34. Chapter 23 Nutritional management in heart failure - p. 279 35. Chapter 24 Management of arrhythmia in chronic heart failure - p. 295 36. Chapter 25 Ivabradine: sinus rhythm control in heart failure - p. 311 37. Chapter 26 Guidelines for the management of chronic heart failure - p. 325 38. Chapter 27 Renin–angiotensin–aldosterone system inhibitors in the heart failure management - p. 343 39. Chapter 28 Beta-blocker therapy among patients with heart failure - p. 351 40. Chapter 29 Treatment of heart failure using angiotensin receptor neprilysin inhibitor - p. 361 41. Chapter 30 Effects of mineralocorticoid antagonist therapy in heart failure - p. 369 42. Chapter 31 Sodium glucose transporters inhibitors in the management of heart failure - p. 377 43. Chapter 32 Role of vasodilators and digitalis in heart failure - p. 389 44. Chapter 33 Vericiguat as part of a multidrug approach following a worsening heart failure event - p. 397 45. Index - p. 409 46. Index - Continued - p. 417
